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Case Report Open Access

Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review

  • Authors:
    • Danli Ye
    • Min Wu
    • Jiawen Zong
    • Weipeng Zeng
    • Guangning Yan
    • Juan Zhou
    • Wei Wang
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, General Hospital of Southern Theater Command, People's Liberation Army of China, Guangzhou, Guangdong 510010, P.R. China, Department of Oncology, General Hospital of Southern Theater Command, People's Liberation Army of China, Guangzhou, Guangdong 510010, P.R. China
    Copyright: © Ye et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 115
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    Published online on: January 20, 2026
       https://doi.org/10.3892/ol.2026.15468
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Abstract

Rhabdomyosarcoma (RMS) with FUS RNA binding protein‑transcription factor cellular promoter 2 (FUS‑TFCP2) fusion is categorized as a subtype of spindle cell/sclerosing RMS. The current study reports a case of rib RMS with FUS‑TFCP2 fusion in a 29‑year‑old male patient who presented with a rib mass that had existed for 3 months without causing any discomfort. A computed tomography scan revealed an occupying lesion at the second rib bone with a surrounding soft‑tissue mass, along with left cervical lymph node metastasis. Histologically, the tumor was composed of fascicles of spindle to epithelioid cells, some of which showed eccentric nuclei resembling rhabdomyoblasts. The stroma was collagenous/sclerotic and occasionally myxoid. Immunohistochemistry revealed positive expression for desmin, myoblast determination protein 1 and smooth muscle actin, with partial expression of anaplastic lymphoma kinase, pan‑CK and myogenin. Next‑generation sequencing confirmed FUS‑TFCP2 fusion and showed deletions in cyclin‑dependent kinase inhibitor (CDKN)2A and CDKN2B. Fluorescence in situ hybridization using a break‑apart probe showed a translocation of TFCP2. Left cervical lymph node metastasis was confirmed. The patient succumbed to the disease 4 months after surgery. RMS with FUS‑TFCP2 fusion is rare, highly aggressive and associated with a poor prognosis.
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1 

Ishiyama T, Kato I, Ito J, Matsumura M, Saito K, Kawabata Y, Kato S, Takeyama M and Fujii S: Rhabdomyosarcoma with FUS::TFCP2 fusion in the scalp: A rare case report depicting round and spindle cell morphology. Int J Surg Pathol. 31:805–812. 2023. View Article : Google Scholar : PubMed/NCBI

2 

Alaggio R, Zhang L, Sung YS, Huang SC, Chen CL, Bisogno G, Zin A, Agaram NP, LaQuaglia MP, Wexler LH and Antonescu CR: A molecular study of pediatric spindle and sclerosing rhabdomyosarcoma: Identification of novel and recurrent VGLL2-related fusions in infantile cases. Am J Surg Pathol. 40:224–235. 2016. View Article : Google Scholar : PubMed/NCBI

3 

Karanian M, Pissaloux D, Gomez-Brouchet A, Chevenet C, Le Loarer F, Fernandez C, Minard V, Corradini N, Castex MP, Duc-Gallet A, et al: SRF-FOXO1 and SRF-NCOA1 fusion genes delineate a distinctive subset of well-differentiated rhabdomyosarcoma. Am J Surg Pathol. 44:607–616. 2020. View Article : Google Scholar : PubMed/NCBI

4 

Agaram NP, LaQuaglia MP, Alaggio R, Zhang L, Fujisawa Y, Ladanyi M, Wexler LH and Antonescu CR: MYOD1-mutant spindle cell and sclerosing rhabdomyosarcoma: An aggressive subtype irrespective of age. A reappraisal for molecular classification and risk stratification. Mod Pathol. 32:27–36. 2019. View Article : Google Scholar : PubMed/NCBI

5 

Agaram NP, Zhang L, Sung YS, Cavalcanti MS, Torrence D, Wexler L, Francis G, Sommerville S, Swanson D, Dickson BC, et al: Expanding the spectrum of intraosseous rhabdomyosarcoma: Correlation between 2 distinct gene fusions and phenotype. Am J Surg Pathol. 43:695–702. 2019. View Article : Google Scholar : PubMed/NCBI

6 

Watson S, Perrin V, Guillemot D, Reynaud S, Coindre JM, Karanian M, Guinebretiere JM, Freneaux P, Le Loarer F, Bouvet M, et al: Transcriptomic definition of molecular subgroups of small round cell sarcomas. J Pathol. 245:29–40. 2018. View Article : Google Scholar : PubMed/NCBI

7 

Le Loarer F, Cleven AHG, Bouvier C, Castex MP, Romagosa C, Moreau A, Salas S, Bonhomme B, Gomez-Brouchet A, Laurent C, et al: A subset of epithelioid and spindle cell rhabdomyosarcomas is associated with TFCP2 fusions and common ALK upregulation. Mod Pathol. 33:404–419. 2020. View Article : Google Scholar : PubMed/NCBI

8 

Dehner CA, Broski SM, Meis JM, Murugan P, Chrisinger JSA, Sosa C, Petersen M, Halling KC, Gupta S and Folpe AL: Fusion-driven spindle cell rhabdomyosarcomas of bone and soft tissue: A clinicopathologic and molecular genetic study of 25 cases. Mod Pathol. 36:1002712023. View Article : Google Scholar : PubMed/NCBI

9 

Si C, Wang Y and Zhu J: A rare case report of intraosseous spindle and epithelioid rhabdomyosarcoma with TFCP2 rearrangement: A pathological diagnostic conundrum and literature review. Int J Surg Pathol. 33:125–130. 2025. View Article : Google Scholar : PubMed/NCBI

10 

Panferova A, Sinichenkova KY, Abu Jabal M, Usman N, Sharlai A, Roshchin V, Konovalov D and Druy A: EWSR1-TFCP2 in an adolescent represents an extremely rare and aggressive form of intraosseous spindle cell rhabdomyosarcomas. Cold Spring Harb Mol Case Stud. 8:a0062092022. View Article : Google Scholar : PubMed/NCBI

11 

Duan FL, Yang H, Gong X, Zuo Z, Qin S, Ji J, Zhou C, Dai J, Guo P and Liu Y: Clinicopathological features of rhabdomyosarcoma with novel FET::TFCP2 and TIMP3::ALK fusion: Report of two cases and literature review. Histopathology. 82:478–484. 2023. View Article : Google Scholar : PubMed/NCBI

12 

Chen XY, Chen G, Zhu Q, Zhu WF, He C and Huang RF: Clinicopathological features of rhabdomyosarcoma with TFCP2 fusions. Zhonghua Bing Li Xue Za Zhi. 51:545–547. 2022.(In Chinese). PubMed/NCBI

13 

Li HL, Mo CH, Xie L, Wu YX, Zeng M and Mao RJ: Clinicopathological study of epithelioid and spindle cell rhabdomysarcoma with EWSR1/FUS-TFCP2 fusion. Zhonghua Bing Li Xue Za Zhi. 53:58–63. 2024.(In Chinese). PubMed/NCBI

14 

Carrillo-Ng H, Liang Y, Chang S, Afkhami M, Gernon T, Bell D and Arias-Stella JA: Complete mimicry: Rhabdomyosarcoma with FUS::TFCP2 fusion masquerading as carcinoma-diagnostic challenge and report of two cases. Genes Chromosomes Cancer. 62:430–436. 2023. View Article : Google Scholar : PubMed/NCBI

15 

Demirkesen C, Danyeli AE, Yildiz P, Ertekin SS, Yilmaz B, Karahan SI and Bahrami A: Cutaneous rhabdomyosarcoma with FUS::TFCP2 fusion: A case report emphasizing early detection. J Cutan Pathol. 50:1059–1064. 2023. View Article : Google Scholar : PubMed/NCBI

16 

Zhu G, Benayed R, Ho C, Mullaney K, Sukhadia P, Rios K, Berry R, Rubin BP, Nafa K, Wang L, et al: Diagnosis of known sarcoma fusions and novel fusion partners by targeted RNA sequencing with identification of a recurrent ACTB-FOSB fusion in pseudomyogenic hemangioendothelioma. Mod Pathol. 32:609–620. 2019. View Article : Google Scholar : PubMed/NCBI

17 

Haug L, Doll J, Appenzeller S, Kunzmann V, Rosenwald A, Maurus K and Gerhard-Hartmann E: Epithelioid and spindle cell rhabdomyosarcoma with EWSR1::TFCP2 fusion mimicking metastatic lung cancer: A case report and literature review. Pathol Res Pract. 249:1547792023. View Article : Google Scholar : PubMed/NCBI

18 

Chrisinger JSA, Wehrli B, Dickson BC, Fasih S, Hirbe AC, Shultz DB, Zadeh G, Gupta AA and Demicco EG: Epithelioid and spindle cell rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusion: Report of two cases. Virchows Arch. 477:725–732. 2020. View Article : Google Scholar : PubMed/NCBI

19 

Koutlas IG, Olson DR and Rawwas J: FET(EWSR1)-TFCP2 Rhabdomyosarcoma: An additional example of this aggressive variant with predilection for the gnathic bones. Head Neck Pathol. 15:374–380. 2021. View Article : Google Scholar : PubMed/NCBI

20 

Xu B, Suurmeijer AJH, Agaram NP, Zhang L and Antonescu CR: Head and neck rhabdomyosarcoma with TFCP2 fusions and ALK overexpression: A clinicopathological and molecular analysis of 11 cases. Histopathology. 79:347–357. 2021. View Article : Google Scholar : PubMed/NCBI

21 

Silva Cunha JL, Cavalcante IL, da Silva Barros CC, Alves PM, Nonaka CFW, Albuquerque AFM, de Almeida OP, de Andrade BAB and Cavalcante RB: Intraosseous rhabdomyosarcoma of the maxilla with TFCP2 fusion: A rare aggressive subtype with predilection for the gnathic bones. Oral Oncol. 130:1058762022. View Article : Google Scholar : PubMed/NCBI

22 

Valerio E, Furtado Costa JL, Perez Fraile NM, Credidio CH, Taveira Garcia MR, Neto CS and Costa FD: Intraosseous spindle Cell/Epithelioid rhabdomyosarcoma with TFCP2 rearrangement: A recent recognized subtype with partial response to alectinib. Int J Surg Pathol. 31:861–865. 2023. View Article : Google Scholar : PubMed/NCBI

23 

Chen F, Wang J, Sun Y and Zhang J: Mandibular rhabdomyosarcoma with TFCP2 rearrangement and osteogenic differentiation: A case misdiagnosed as fibrous dysplasia or low-grade central osteosarcoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 137:e143–e149. 2024. View Article : Google Scholar : PubMed/NCBI

24 

Schöpf J, Uhrig S, Heilig CE, Lee KS, Walther T, Carazzato A, Dobberkau AM, Weichenhan D, Plass C, Hartmann M, et al: Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions. Nat Commun. 15:512024. View Article : Google Scholar : PubMed/NCBI

25 

Machado I, Wardelmann E, Zhao M, Song J, Wang Y, Braun SA, Catasus L, Ferre M, Leoveanu I, Westhoff J, et al: Primary cutaneous rhabdomyosarcoma with EWSR1/FUS::TFCP2 fusion: Four new cases with distinctive morphology, immunophenotypic, and genetic profile. Virchows Arch. 486:1187–1198. 2025. View Article : Google Scholar : PubMed/NCBI

26 

Flaitz C and Hicks J: Primary Intraosseous Rhabdomyosarcoma: Rare Subtype Involving Mandible with Unique Translocation. Oral Surgery Oral Med Oral Pathol Oral Radiol. 133:1572022. View Article : Google Scholar

27 

Zhong P, Wei S, Xiao H and Zeng Y: Rhabdomyosarcoma with FUS::TFCP2 fusion in the mandible: A rare aggressive subtype, but can be misdiagnosed as ossifying fibroma. Int J Surg Pathol. 32:758–766. 2024. View Article : Google Scholar : PubMed/NCBI

28 

Gallagher KPD, Roza A, Tager E, Mariz B, Soares CD, Rocha AC, Abrahao AC, Romanach MJ, Carlos R, Hunter KD, et al: Rhabdomyosarcoma with TFCP2 rearrangement or typical Co-expression of AE1/AE3 and ALK: Report of three new cases in the head and neck region and literature review. Head Neck Pathol. 17:546–561. 2023. View Article : Google Scholar : PubMed/NCBI

29 

Tagami Y, Sugita S, Kubo T, Iesato N, Emori M, Takada K, Tsujiwaki M, Segawa K, Sugawara T, Kikuchi T and Hasegawa T: Spindle cell rhabdomyosarcoma in a lumbar vertebra with FUS-TFCP2 fusion. Pathol Res Pract. 215:1523992019. View Article : Google Scholar : PubMed/NCBI

30 

Dashti NK, Wehrs RN, Thomas BC, Nair A, Davila J, Buckner JC, Martinez AP, Sukov WR, Halling KC, Howe BM and Folpe AL: Spindle cell rhabdomyosarcoma of bone with FUS-TFCP2 fusion: Confirmation of a very recently described rhabdomyosarcoma subtype. Histopathology. 73:514–520. 2018. View Article : Google Scholar : PubMed/NCBI

31 

Bradova M, Mosaieby E, Michal M, Vanecek T, Ing SK, Grossmann P, Koshyk O, Kinkor Z, Laciok S, Nemcova A, et al: Spindle cell rhabdomyosarcomas: With TFCP2 rearrangements, and novel EWSR1::ZBTB41 and PLOD2::RBM6 gene fusions. A study of five cases and review of the literature. Histopathology. 84:776–793. 2024. View Article : Google Scholar : PubMed/NCBI

32 

Csizmok V, Grisdale CJ, Williamson LM, Lim HJ, Lee L, Renouf DJ, Jones SJM, Marra MA, Laskin J and Smrke A: Diagnostic and therapeutic implications of a FUS::TFCP2 fusion and ALK activation in a metastatic rhabdomyosarcoma. Genes Chromosomes Cancer. 63:e232592024. View Article : Google Scholar : PubMed/NCBI

33 

Li Y, Li D, Wang J and Tang J: Epithelioid and spindle rhabdomyosarcoma with TFCP2 rearrangement in abdominal wall: A distinctive entity with poor prognosis. Diagn Pathol. 18:412023. View Article : Google Scholar : PubMed/NCBI

34 

Fang Z, Duan C, Wang S, Fu L, Yang P, Yu T, Deel MD, Lau LMS, Ma X, Ni X and Su Y: Pediatric spindle cell/sclerosing rhabdomyosarcoma with FUS-TFCP2 fusion: A case report and literature review. Transl Pediatr. 13:178–191. 2024. View Article : Google Scholar : PubMed/NCBI

35 

Plotzke JM, Rabah R, Robinson DR, Edmonds A, Bloom DA, Mody R and Heider A: Primary intraosseous spindle cell rhabdomyosarcoma: A case report in an unusual location. Pediatr Dev Pathol. 27:597–602. 2024. View Article : Google Scholar : PubMed/NCBI

36 

Ma Y, Feng J, Ding D, Zhao J and Tian F: TFCP2-rearranged epithelioid and spindle cell rhabdomyosarcoma in the bladder: A rare case in an 8-year-old female child. Pediatr Blood Cancer. 70:e299352023. View Article : Google Scholar : PubMed/NCBI

37 

Brunac AC, Laprie A, Castex MP, Laurent C, Le Loarer F, Karanian M, Le Guellec S, Guillemot D, Pierron G and Gomez-Brouchet A: The combination of radiotherapy and ALK inhibitors is effective in the treatment of intraosseous rhabdomyosarcoma with FUS-TFCP2 fusion transcript. Pediatr Blood Cancer. 67:e281852020. View Article : Google Scholar : PubMed/NCBI

38 

Ginn MP, Denu RA, Ingram DR, Wani KM, Lazar AJ, Harrison DJ, Nakazawa MS, Conley AP, Patel S and Livingston JA: TFCP2 Fusion-Positive Rhabdomyosarcomas: A Report of 10 cases and a review of the literature. Cancers (Basel). 17:14412025. View Article : Google Scholar : PubMed/NCBI

39 

Kotarba G, Krzywinska E, Grabowska AI, Taracha A and Wilanowski T: TFCP2/TFCP2L1/UBP1 transcription factors in cancer. Cancer Lett. 420:72–79. 2018. View Article : Google Scholar : PubMed/NCBI

40 

Hsu WH, LaBella KA, Lin Y, Xu P, Lee R, Hsieh CE, Yang L, Zhou A, Blecher JM, Wu CJ, et al: Oncogenic KRAS drives lipofibrogenesis to promote angiogenesis and colon cancer progression. Cancer Discov. 13:2652–2673. 2023. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Ye D, Wu M, Zong J, Zeng W, Yan G, Zhou J and Wang W: Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review. Oncol Lett 31: 115, 2026.
APA
Ye, D., Wu, M., Zong, J., Zeng, W., Yan, G., Zhou, J., & Wang, W. (2026). Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review. Oncology Letters, 31, 115. https://doi.org/10.3892/ol.2026.15468
MLA
Ye, D., Wu, M., Zong, J., Zeng, W., Yan, G., Zhou, J., Wang, W."Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review". Oncology Letters 31.3 (2026): 115.
Chicago
Ye, D., Wu, M., Zong, J., Zeng, W., Yan, G., Zhou, J., Wang, W."Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review". Oncology Letters 31, no. 3 (2026): 115. https://doi.org/10.3892/ol.2026.15468
Copy and paste a formatted citation
x
Spandidos Publications style
Ye D, Wu M, Zong J, Zeng W, Yan G, Zhou J and Wang W: Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review. Oncol Lett 31: 115, 2026.
APA
Ye, D., Wu, M., Zong, J., Zeng, W., Yan, G., Zhou, J., & Wang, W. (2026). Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review. Oncology Letters, 31, 115. https://doi.org/10.3892/ol.2026.15468
MLA
Ye, D., Wu, M., Zong, J., Zeng, W., Yan, G., Zhou, J., Wang, W."Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review". Oncology Letters 31.3 (2026): 115.
Chicago
Ye, D., Wu, M., Zong, J., Zeng, W., Yan, G., Zhou, J., Wang, W."Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review". Oncology Letters 31, no. 3 (2026): 115. https://doi.org/10.3892/ol.2026.15468
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