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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

  • Authors:
    • Abdulrahman Alaseem
    • Hatim Khoja
    • Khalid Murrad
    • Sarah Alkhalife
    • Nouf Altwaijri
    • Abdullah Almawi
    • Abdulaziz Bin Dakhil
    • Abdulaziz Alhammad
    • Banan Alqady
    • Eman Najjar
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh 12372, Saudi Arabia, Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia, Department of Orthopedics, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia, Department of Orthopedics, King Saud Medical City, Riyadh 12746, Saudi Arabia, Department of Orthopedic Surgery, King Saud University Medical City, Riyadh 12372, Saudi Arabia, Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia, College of Medicine, King Saud University, Riyadh 12372, Saudi Arabia, Department of Radiology, Security Forces Hospital, Riyadh 12233, Saudi Arabia
    Copyright: © Alaseem et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 271
    |
    Published online on: April 28, 2026
       https://doi.org/10.3892/ol.2026.15626
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Abstract

Clear cell sarcoma (CCS) is an uncommon malignancy originating from neural crest cells; this type of cancer can mimic a number of other tumors and frequently presents in the lower limbs, but is occasionally found in atypical locations. The present study describes a rare case of a 14‑year‑old girl presenting with a subungual swelling on the right index finger, with the initial impression of a glomus tumor, who underwent unplanned surgical resection at another institution. The histopathological analysis revealed CCS with positive margins, and the patient was therefore referred to an orthopedic oncology specialist King Khalid University Hospital (King Saud University Medical City, Riyadh, Saudi Arabia), for further management. Local and systemic staging workups confirmed localized disease; hence, local control was achieved by amputation at the base of the middle phalanx level, with negative margins achieved without chemotherapy or radiation therapy. Finger tumors may impose diagnostic challenges due to their rarity and similarity with more common benign conditions. A high index of suspicion is important to make an early, accurate diagnosis, and to avoid inappropriate management and poor outcomes. The current case is one of the few published reports of CCS arising in the finger and, to the best of our knowledge, the second pediatric case. Therefore, the present study contributes to the limited literature on CCS presenting in an unusual location such as the hand, with the aim of avoiding errors in diagnosis and management.
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Copy and paste a formatted citation
Spandidos Publications style
Alaseem A, Khoja H, Murrad K, Alkhalife S, Altwaijri N, Almawi A, Bin Dakhil A, Alhammad A, Alqady B, Najjar E, Najjar E, et al: A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report. Oncol Lett 32: 271, 2026.
APA
Alaseem, A., Khoja, H., Murrad, K., Alkhalife, S., Altwaijri, N., Almawi, A. ... Najjar, E. (2026). A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report. Oncology Letters, 32, 271. https://doi.org/10.3892/ol.2026.15626
MLA
Alaseem, A., Khoja, H., Murrad, K., Alkhalife, S., Altwaijri, N., Almawi, A., Bin Dakhil, A., Alhammad, A., Alqady, B., Najjar, E."A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report". Oncology Letters 32.1 (2026): 271.
Chicago
Alaseem, A., Khoja, H., Murrad, K., Alkhalife, S., Altwaijri, N., Almawi, A., Bin Dakhil, A., Alhammad, A., Alqady, B., Najjar, E."A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report". Oncology Letters 32, no. 1 (2026): 271. https://doi.org/10.3892/ol.2026.15626
Copy and paste a formatted citation
x
Spandidos Publications style
Alaseem A, Khoja H, Murrad K, Alkhalife S, Altwaijri N, Almawi A, Bin Dakhil A, Alhammad A, Alqady B, Najjar E, Najjar E, et al: A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report. Oncol Lett 32: 271, 2026.
APA
Alaseem, A., Khoja, H., Murrad, K., Alkhalife, S., Altwaijri, N., Almawi, A. ... Najjar, E. (2026). A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report. Oncology Letters, 32, 271. https://doi.org/10.3892/ol.2026.15626
MLA
Alaseem, A., Khoja, H., Murrad, K., Alkhalife, S., Altwaijri, N., Almawi, A., Bin Dakhil, A., Alhammad, A., Alqady, B., Najjar, E."A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report". Oncology Letters 32.1 (2026): 271.
Chicago
Alaseem, A., Khoja, H., Murrad, K., Alkhalife, S., Altwaijri, N., Almawi, A., Bin Dakhil, A., Alhammad, A., Alqady, B., Najjar, E."A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report". Oncology Letters 32, no. 1 (2026): 271. https://doi.org/10.3892/ol.2026.15626
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