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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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August-2026 Volume 32 Issue 2

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

  • Authors:
    • Yuanyuan Kong
    • Liangxue Zhu
    • Yuelan Xiao
  • View Affiliations / Copyright

    Affiliations: Intensive Care Unit, Nanjing Gaochun People's Hospital, Nanjing, Jiangsu 211300, P.R. China, Department of Oncology, Nanjing Gaochun People's Hospital, Nanjing, Jiangsu 211300, P.R. China
  • Article Number: 327
    |
    Published online on: June 5, 2026
       https://doi.org/10.3892/ol.2026.15682
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Abstract

Although autoimmune hemolytic anemia (AIHA) is a well‑known paraneoplastic syndrome in hematologic malignancies, it has rarely been reported in solid tumors. Documented cases of secondary warm AIHA (wAIHA) linked to solid tumors, particularly cervical cancer, are exceedingly rare. The present study reports 1 case of wAIHA occurring in a 73‑year‑old patient following radical chemoradiotherapy for cervical cancer. To the best of our knowledge, this association between wAIHA and cervical cancer has not been previously reported. The present case report highlights cervical cancer as a novel etiology of secondary AIHA and emphasizes the need for clinical vigilance to avoid diagnostic delays in post‑treatment anemia.
View Figures

Figure 1

(A) H&E staining of cervical
biopsy tissue showing characteristic squamous cell carcinoma
(magnification, ×100; scale bar, 100 µm). (B) A soft tissue mass
measuring ~11×20×20 mm is observed on the anterior cervical wall,
with relatively well-defined margins. Early dynamic enhancement
showed notable contrast enhancement. The red arrow indicates the
location of the tumor. (C) Bone marrow smear cytology showed active
proliferation of nucleated cells with prominent erythroid
hyperplasia, notably with a marked increase in late-stage
erythrocytes (magnification, ×1,000; scale bar, 10 µm). The red
arrows indicate areas of active proliferation and late-stage
erythrocytes.
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Copy and paste a formatted citation
Spandidos Publications style
Kong Y, Zhu L and Xiao Y: Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report. Oncol Lett 32: 327, 2026.
APA
Kong, Y., Zhu, L., & Xiao, Y. (2026). Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report. Oncology Letters, 32, 327. https://doi.org/10.3892/ol.2026.15682
MLA
Kong, Y., Zhu, L., Xiao, Y."Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report". Oncology Letters 32.2 (2026): 327.
Chicago
Kong, Y., Zhu, L., Xiao, Y."Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report". Oncology Letters 32, no. 2 (2026): 327. https://doi.org/10.3892/ol.2026.15682
Copy and paste a formatted citation
x
Spandidos Publications style
Kong Y, Zhu L and Xiao Y: Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report. Oncol Lett 32: 327, 2026.
APA
Kong, Y., Zhu, L., & Xiao, Y. (2026). Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report. Oncology Letters, 32, 327. https://doi.org/10.3892/ol.2026.15682
MLA
Kong, Y., Zhu, L., Xiao, Y."Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report". Oncology Letters 32.2 (2026): 327.
Chicago
Kong, Y., Zhu, L., Xiao, Y."Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report". Oncology Letters 32, no. 2 (2026): 327. https://doi.org/10.3892/ol.2026.15682
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