|
1
|
Cao W, Chen HD, Yu YW, Li N and Chen WQ:
Changing profiles of cancer burden worldwide and in China: A
secondary analysis of the global cancer statistics 2020. Chin Med J
(Engl). 134:783–791. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bray F, Laversanne M, Sung H, Ferlay J,
Siegel RL, Soerjomataram I and Jemal A: Global cancer statistics
2022: GLOBOCAN estimates of incidence and mortality worldwide for
36 cancers in 185 countries. CA Cancer J Clin. 74:229–263.
2024.PubMed/NCBI
|
|
3
|
Dixon SJ, Lemberg KM, Lamprecht MR, Skouta
R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS,
et al: Ferroptosis: An iron-dependent form of nonapoptotic cell
death. Cell. 149:1060–1072. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Stockwell BR, Friedmann Angeli JP, Bayir
H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK,
Kagan VE, et al: Ferroptosis: A regulated cell death nexus linking
metabolism, redox biology, and disease. Cell. 171:273–285. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Jiang X, Stockwell BR and Conrad M:
Ferroptosis: Mechanisms, biology and role in disease. Nat Rev Mol
Cell Biol. 22:266–282. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Hassannia B, Vandenabeele P and Vanden
Berghe T: Targeting ferroptosis to iron out cancer. Cancer Cell.
35:830–849. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Lei G, Zhuang L and Gan B: Targeting
ferroptosis as a vulnerability in cancer. Nat Rev Cancer.
22:381–396. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Chen X, Kang R, Kroemer G and Tang D:
Broadening horizons: The role of ferroptosis in cancer. Nat Rev
Clin Oncol. 18:280–296. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ma R, Shimura T, Yin C, Okugawa Y,
Kitajima T, Koike Y, Okita Y, Ohi M, Uchida K, Goel A, et al:
Antitumor effects of Andrographis via ferroptosis-associated genes
in gastric cancer. Oncol Lett. 22:5232021. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Mancias JD, Wang X, Gygi SP, Harper JW and
Kimmelman AC: Quantitative proteomics identifies NCOA4 as the cargo
receptor mediating ferritinophagy. Nature. 509:105–109. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Doll S, Proneth B, Tyurina YY, Panzilius
E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A,
et al: ACSL4 dictates ferroptosis sensitivity by shaping cellular
lipid composition. Nat Chem Biol. 13:91–98. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kagan VE, Mao G, Qu F, Angeli JP, Doll S,
Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, et al: Oxidized
arachidonic and adrenic phosphatidylethanolamines navigate cells to
ferroptosis. Nat Chem Biol. 13:81–90. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Yang WS, SriRamaratnam R, Welsch ME,
Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji
AF, Clish CB, et al: Regulation of ferroptotic cancer cell death by
GPX4. Cell. 156:317–331. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Bersuker K, Hendricks JM, Li Z, Magtanong
L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, et al:
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit
ferroptosis. Nature. 575:688–692. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Doll S, Freitas FP, Shah R, Aldrovandi M,
da Silva MC, Ingold I, Goya Grocin A, Xavier da Silva TN, Panzilius
E, Scheel CH, et al: FSP1 is a glutathione-independent ferroptosis
suppressor. Nature. 575:693–698. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Jiang L, Kon N, Li T, Wang SJ, Su T,
Hibshoosh H, Baer R and Gu W: Ferroptosis as a p53-mediated
activity during tumour suppression. Nature. 520:57–62. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lagergren J, Smyth E, Cunningham D and
Lagergren P: Oesophageal cancer. Lancet. 390:2383–2396. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Maimaitizunong R, Wang K and Li H:
Ferroptosis and its emerging role in esophageal cancer. Front Mol
Biosci. 9:10279122022. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Yang JY, Lei XY, He KY, Guo JR, Liu MJ, Li
JQ, Li QT, Jiang ZH, Zhang L, Wu DH, et al: HMGA1 drives
chemoresistance in esophageal squamous cell carcinoma by
suppressing ferroptosis. Cell Death Dis. 15:1582024. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Tao H, Song SJ, Fan ZW, Li WT, Jin X,
Jiang W, Bai J and Shi ZZ: PKCiota inhibits the ferroptosis of
esophageal cancer cells via suppressing USP14-mediated autophagic
degradation of GPX4. Antioxidants (Basel). 13:1142024. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang S, Guo J, Zhang H, Tong L and Zhang
L: Gliotoxin induced ferroptosis by downregulating SUV39H1
expression in esophageal cancer cells. Recent Pat Anticancer Drug
Discov. 18:397–407. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wang XW, Yang ZY, Li T, Zhao XR, Li XZ and
Wang XX: Verteporfin exerts anticancer effects and reverses
resistance to paclitaxel via inducing ferroptosis in esophageal
squamous cell cancer cells. Mol Biotechnol. 66:2558–2568. 2024.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ballout F, Lu H, Chen Z, Hu T, Chen L,
Washington MK, El-Rifai W and Peng D: Targeting NRF2 sensitizes
esophageal adenocarcinoma cells to cisplatin through induction of
ferroptosis and apoptosis. Antioxidants (Basel). 11:18592022.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Liu CC, Li HH, Lin JH, Chiang MC, Hsu TW,
Li AF, Yen DH, Hsu HS and Hung SC: Esophageal cancer stem-like
cells resist ferroptosis-induced cell death by active Hsp27-GPX4
pathway. Biomolecules. 12:482021. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Zhang J, Wang N, Zhou Y, Wang K, Sun Y,
Yan H, Han W, Wang X, Wei B, Ke Y and Xu X: Oridonin induces
ferroptosis by inhibiting gamma-glutamyl cycle in TE1 cells.
Phytother Res. 35:494–503. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Newman DJ and Cragg GM: Natural products
as sources of new drugs over the nearly four decades from 01/1981
to 09/2019. J Nat Prod. 83:770–803. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Li S and Zhang B: Traditional Chinese
medicine network pharmacology: Theory, methodology and application.
Chin J Nat Med. 11:110–120. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Smyth EC, Nilsson M, Grabsch HI, van
Grieken NCT and Lordick F: Gastric cancer. Lancet. 396:635–648.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Yang Z, Zou S, Zhang Y, Zhang J, Zhang P,
Xiao L, Xie Y, Meng M, Feng J, Kang L, et al: ACTL6A protects
gastric cancer cells against ferroptosis through induction of
glutathione synthesis. Nat Commun. 14:41932023. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Jian H, Chen ZQ, Du H, Liao T, Sun YC, Ke
D and Yu Y: Inhibition of ferroptosis by POLE2 in gastric cancer
cells involves the activation of NRF2/GPX4 pathway. J Cell Mol Med.
28:e179832024. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Tu RH, Wu SZ, Huang ZN, Zhong Q, Ye YH,
Zheng CH, Xie JW, Wang JB, Lin JX, Chen QY, et al: Neurotransmitter
receptor HTR2B regulates lipid metabolism to inhibit ferroptosis in
gastric cancer. Cancer Res. 83:3868–3885. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zhang H, Deng T, Liu R, Ning T, Yang H,
Liu D, Zhang Q, Lin D, Ge S, Bai M, et al: CAF secreted miR-522
suppresses ferroptosis and promotes acquired chemo-resistance in
gastric cancer. Mol Cancer. 19:432020. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Lee JY, Nam M, Son HY, Hyun K, Jang SY,
Kim JW, Kim MW, Jung Y, Jang E, Yoon SJ, et al: Polyunsaturated
fatty acid biosynthesis pathway determines ferroptosis sensitivity
in gastric cancer. Proc Natl Acad Sci USA. 117:32433–32442. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Guan X, Wang Y, Yu W, Wei Y, Lu Y, Dai E,
Dong X, Zhao B, Hu C, Yuan L, et al: Blocking ubiquitin-specific
peptidase 7 induces ferroptosis in gastric cancer via targeting
stearoyl-CoA desaturase. Adv Sci (Weinh). 11:e23078992024.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Zhao L, Peng Y, He S, Li R, Wang Z, Huang
J, Lei X, Li G and Ma Q: Apatinib induced ferroptosis by lipid
peroxidation in gastric cancer. Gastric Cancer. 24:642–654. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Peng Y, Lei X, Yang Q, Zhang G, He S, Wang
M, Ling R, Zheng B, He J, Chen X, et al: Helicobacter pylori
CagA-mediated ether lipid biosynthesis promotes ferroptosis
susceptibility in gastric cancer. Exp Mol Med. 56:441–452. 2024.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Hu C, Zu D, Xu J, Xu H, Yuan L, Chen J,
Wei Q, Zhang Y, Han J, Lu T, et al: Polyphyllin B suppresses
gastric tumor growth by modulating iron metabolism and inducing
ferroptosis. Int J Biol Sci. 19:1063–1079. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Ding L, Dang S, Sun M, Zhou D, Sun Y, Li
E, Peng S, Li J and Li G: Quercetin induces ferroptosis in gastric
cancer cells by targeting SLC1A5 and regulating the p-Camk2/p-DRP1
and NRF2/GPX4 axes. Free Radic Biol Med. 213:150–163. 2024.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Yuan J, Khan SU, Yan J, Lu J, Yang C and
Tong Q: Baicalin enhances the efficacy of 5-fluorouracil in gastric
cancer by promoting ROS-mediated ferroptosis. Biomed Pharmacother.
164:1149862023. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Ye C, Yao Z, Wang Y and Zhang C:
Asiaticoside promoted ferroptosis and suppressed immune escape in
gastric cancer cells by downregulating the Wnt/β-catenin pathway.
Int Immunopharmacol. 134:1121752024. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Ni H, Ruan G, Sun C, Yang X, Miao Z, Li J,
Chen Y, Qin H, Liu Y, Zheng L, et al: Tanshinone IIA inhibits
gastric cancer cell stemness through inducing ferroptosis. Environ
Toxicol. 37:192–200. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Llovet JM, Kelley RK, Villanueva A, Singal
AG, Pikarsky E, Roayaie S, Lencioni R, Koike K, Zucman-Rossi J and
Finn RS: Hepatocellular carcinoma. Nat Rev Dis Primers. 7:62021.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Zhang D, Man D, Lu J, Jiang Y, Ding B, Su
R, Tong R, Chen J, Yang B, Zheng S, et al: Mitochondrial TSPO
promotes hepatocellular carcinoma progression through ferroptosis
inhibition and immune evasion. Adv Sci (Weinh). 10:e22066692023.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Yang M, Wu X, Hu J, Wang Y, Wang Y, Zhang
L, Huang W, Wang X, Li N, Liao L, et al: COMMD10 inhibits HIF1α/CP
loop to enhance ferroptosis and radiosensitivity by disrupting
Cu-Fe balance in hepatocellular carcinoma. J Hepatol. 76:1138–1150.
2022. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Hu X, He Y, Han Z, Liu W, Liu D, Zhang X,
Chen L, Qi L, Chen L, Luo Y, et al: PNO1 inhibits
autophagy-mediated ferroptosis by GSH metabolic reprogramming in
hepatocellular carcinoma. Cell Death Dis. 13:10102022. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Bi F, Qiu Y, Wu Z, Liu S, Zuo D, Huang Z,
Li B, Yuan Y, Niu Y and Qiu J: METTL9-SLC7A11 axis promotes
hepatocellular carcinoma progression through ferroptosis
inhibition. Cell Death Discov. 9:4282023. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Suzuki S, Venkatesh D, Kanda H, Nakayama
A, Hosokawa H, Lee E, Miki T, Stockwell BR, Yokote K, Tanaka T and
Prives C: GLS2 is a tumor suppressor and a regulator of ferroptosis
in hepatocellular carcinoma. Cancer Res. 82:3209–3222. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Chen Y, Li L, Lan J, Cui Y, Rao X, Zhao J,
Xing T, Ju G, Song G, Lou J and Liang J: CRISPR screens uncover
protective effect of PSTK as a regulator of chemotherapy-induced
ferroptosis in hepatocellular carcinoma. Mol Cancer. 21:112022.
View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Huang SC, Chen YM, Hu YY, Shi YJ, Xiao QW,
Li Z, Kang JL, Zhou Q, Shen G and Jia HY: Downregulation of MCF2L
promoted the ferroptosis of hepatocellular carcinoma cells through
PI3K/mTOR pathway in a RhoA/Rac1 dependent manner. Dis Markers.
2022:61389412022. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Li ZJ, Dai HQ, Huang XW, Feng J, Deng JH,
Wang ZX, Yang XM, Liu YJ, Wu Y, Chen PH, et al: Artesunate
synergizes with sorafenib to induce ferroptosis in hepatocellular
carcinoma. Acta Pharmacol Sin. 42:301–310. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Chen GQ, Benthani FA, Wu J, Liang D, Bian
ZX and Jiang X: Artemisinin compounds sensitize cancer cells to
ferroptosis by regulating iron homeostasis. Cell Death Differ.
27:242–254. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Jiang X, Li H and Liu Y: Cyclovirobuxine D
inhibits hepatocellular carcinoma growth by inducing ferroptosis of
hepatocellular carcinoma cells. Discov Oncol. 15:962024. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Luo P, Zhang Q, Shen S, An Y, Yuan L, Wong
YK, Huang S, Huang S, Huang J, Cheng G, et al: Mechanistic
engineering of celastrol liposomes induces ferroptosis and
apoptosis by directly targeting VDAC2 in hepatocellular carcinoma.
Asian J Pharm Sci. 18:1008742023.PubMed/NCBI
|
|
54
|
Xie J, Wang H, Xie W, Liu Y and Chen Y:
Gallic acid promotes ferroptosis in hepatocellular carcinoma via
inactivating Wnt/β-catenin signaling pathway. Naunyn Schmiedebergs
Arch Pharmacol. 397:2437–2445. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Wu W, Zhao Y, Qin B, Jiang X, Wang C, Hu
R, Ma R, Lee MH, Liu H, Li K and Yuan P: Non-canonical role of
UCKL1 on ferroptosis defence in colorectal cancer. EBioMedicine.
93:1046502023. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Liu W, Liu C, Xiao J, Qian C, Chen Z, Lin
W, Zhang Y, Wu J, Zhou R and Zhao L: HTRA1 interacts with SLC7A11
to modulate colorectal cancer chemosensitivity by inhibiting
ferroptosis. Cell Death Discov. 10:2282024. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Zhang Q, Deng T, Zhang H, Zuo D, Zhu Q,
Bai M, Liu R, Ning T, Zhang L, Yu Z, et al: Adipocyte-derived
exosomal MTTP suppresses ferroptosis and promotes chemoresistance
in colorectal cancer. Adv Sci (Weinh). 9:e22033572022. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Li H, Yu K, Hu H, Zhang X, Zeng S, Li J,
Dong X, Deng X, Zhang J and Zhang Y: METTL17 coordinates
ferroptosis and tumorigenesis by regulating mitochondrial
translation in colorectal cancer. Redox Biol. 71:1030872024.
View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Liu J, Lu X, Zeng S, Fu R, Wang X, Luo L,
Huang T, Deng X, Zheng H, Ma S, et al: ATF3-CBS signaling axis
coordinates ferroptosis and tumorigenesis in colorectal cancer.
Redox Biol. 71:1031182024. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Bian Z, Sun X, Liu L, Qin Y, Zhang Q, Liu
H, Mao L and Sun S: Sodium butyrate induces CRC cell ferroptosis
via the CD44/SLC7A11 pathway and exhibits a synergistic therapeutic
effect with erastin. Cancers (Basel). 15:4232023. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Martino E, Balestrieri A, Aragona F,
Bifulco G, Mele L, Campanile G, Balestrieri ML and D'Onofrio N:
MiR-148a-3p promotes colorectal cancer cell ferroptosis by
targeting SLC7A11. Cancers (Basel). 15:43422023. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Miao Q, Deng WQ, Lyu WY, Sun ZT, Fan SR,
Qi M, Qiu SH, Zhu YR, Lin JP, Chen MF and Deng LJ: Erianin inhibits
the growth and metastasis through autophagy-dependent ferroptosis
in KRASG13D colorectal cancer. Free Radic Biol Med. 204:301–312.
2023. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Lian G, Huang XX and Zeng Y: Puerarin
induces ferroptosis in colorectal cancer cells via triggering NCOA4
upregulation. Nutr Cancer. 75:1571–1578. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Ma X, Li Y, Liang D, Jiang F, Zhang L,
Song W, Wan B, Xia C and Lu Q: Solanine induces ferroptosis in
colorectal cancer cells through ALOX12B/ADCY4 molecular axis. J
Pharm Pharmacol. 76:224–235. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Zhou X, Kang J, Zhang L and Cheng Y:
Osthole inhibits malignant phenotypes and induces ferroptosis in
KRAS-mutant colorectal cancer cells via suppressing AMPK/Akt
signaling. Cancer Chemother Pharmacol. 92:119–134. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Wu Y, Pi D, Zhou S, Yi Z, Dong Y, Wang W,
Ye H, Chen Y, Zuo Q and Ouyang M: Ginsenoside Rh3 induces
pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in
colorectal cancer cells. Acta Biochim Biophys Sin (Shanghai).
55:587–600. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Liu J, Meng Y, Li B, Wang P, Wan X, Huang
W and Li R: Ferroptosis-related biotargets and network mechanisms
of fucoidan against colorectal cancer: An integrated bioinformatic
and experimental approach. Int J Biol Macromol. 222:1522–1530.
2022. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Kleeff J, Korc M, Apte M, La Vecchia C,
Johnson CD, Biankin AV, Neale RE, Tempero M, Tuveson DA, Hruban RH
and Neoptolemos JP: Pancreatic cancer. Nat Rev Dis Primers.
2:160222016. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Halbrook CJ, Lyssiotis CA, Pasca di
Magliano M and Maitra A: Pancreatic cancer: Advances and
challenges. Cell. 186:1729–1754. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Wang Y, Liu Y, Wang C, Kang R, Tang D and
Liu J: EP300 promotes ferroptosis via HSPA5 acetylation in
pancreatic cancer. Sci Rep. 13:150042023. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Zhu Y, Fang S, Fan B, Xu K, Xu L, Wang L,
Zhu L, Chen C, Wu R, Ni J and Wang J: Cancer-associated fibroblasts
reprogram cysteine metabolism to increase tumor resistance to
ferroptosis in pancreatic cancer. Theranostics. 14:1683–1700. 2024.
View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Wang W, Green M, Choi JE, Gijón M, Kennedy
PD, Johnson JK, Liao P, Lang X, Kryczek I, Sell A, et al: CD8+ T
cells regulate tumour ferroptosis during cancer immunotherapy.
Nature. 569:270–274. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Lang X, Green MD, Wang W, Yu J, Choi JE,
Jiang L, Liao P, Zhou J, Zhang Q, Dow A, et al: Radiotherapy and
immunotherapy promote tumoral lipid oxidation and ferroptosis via
synergistic repression of SLC7A11. Cancer Discov. 9:1673–1685.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Liu Q, Lu JJ, Hong HJ, Yang Q, Wang Y and
Chen XJ: Ophiopogon japonicus and its active compounds: A review of
potential anticancer effects and underlying mechanisms.
Phytomedicine. 113:1547182023. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Zhang L, Li C, Zhang Y, Zhang J and Yang
X: Ophiopogonin B induces gastric cancer cell death by blocking the
GPX4/SLC7A11-dependent ferroptosis pathway. Oncol Lett. 23:1042022.
View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Bouayed J and Bohn T: Exogenous
antioxidants-double-edged swords in cellular redox state: Health
beneficial effects at physiologic doses versus deleterious effects
at high doses. Oxid Med Cell Longev. 3:228–237. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Liu J, Kang R and Tang D: Signaling
pathways and defense mechanisms of ferroptosis. FEBS J.
289:7038–7050. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Gao M, Monian P, Quadri N, Ramasamy R and
Jiang X: Glutaminolysis and transferrin regulate ferroptosis. Mol
Cell. 59:298–308. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Shimada K, Skouta R, Kaplan A, Yang WS,
Hayano M, Dixon SJ, Brown LM, Valenzuela CA, Wolpaw AJ and
Stockwell BR: Global survey of cell death mechanisms reveals
metabolic regulation of ferroptosis. Nat Chem Biol. 12:497–503.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Mishima E, Nakamura T, Doll S, Proneth B,
Fedorova M, Pratt DA, Friedmann Angeli JP, Dixon SJ, Wahida A and
Conrad M: Recommendations for robust and reproducible research on
ferroptosis. Nat Rev Mol Cell Biol. 26:615–630. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Lagoa R, Silva J, Rodrigues JR and
Bishayee A: Advances in phytochemical delivery systems for improved
anticancer activity. Biotechnol Adv. 38:1073822020. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Diao J, Jia Y, Dai E, Liu J, Kang R, Tang
D, Han L, Zhong Y and Meng L: Ferroptotic therapy in cancer:
Benefits, side effects, and risks. Mol Cancer. 23:892024.
View Article : Google Scholar : PubMed/NCBI
|