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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Discovery of novel cancer therapeutic targets and drugs

Lead Editor: Professor FUWEN YUAN, Shanghai University of Traditional Chinese Medicine, China

Guest Editors:
  • Dr Fengjing Jia ,  Shanghai University of Traditional Chinese Medicine ,  China

Despite significant progress made towards the identification of novel therapeutic targets and the discovery of potent chemotherapeutic agents, cancer incidence and mortality are rapidly growing worldwide, and it is one of the leading causes of death. Targeted therapies are one of the primary treatment strategies for cancers, especially after the cancer progresses to metastasis status. However, the intrinsic off-target toxicity of the current anticancer drugs as well as the rapid genetic evolution of cancer cells limited the therapeutic efficiency and led to the cancer eventually developing drug resistance. Thus, the identification of novel cancer therapeutic targets and the screening and development of cancer-targeted drugs are urgently needed. The aim of this special issue is to invite submissions of original articles and reviews tackling the discovery of novel cancer therapeutics targets and new drugs with potential anticancer activities. Studies employing in vitro cancer cell models and in vivo animal models with mechanism studies are welcome.


Submission deadline: 16/03/2026 | Views:
Journal Cover
March-2026 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Immune microenvironment and treatment response of dMMR gastric cancer: Heterogeneity and implications for immunotherapy

Liping Wang, Xinliang Zhong, Mengxing Diao, Wei Deng
Article Number: 119
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑150 upregulation reduces osteosarcoma cell invasion and metastasis by downregulating Ezrin

Ce Zhan, Cheng Li, Hao Zhang, Hao Tang, Fang Ji, Su-Chi Qiao, Wei-Dong Xu, Zhi-Wei Wang
Article Number: 118
Published online on: 26 January 2026

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Article Open Access

Unveiling mitochondrial DNA copy number alterations: Insights into progression from cervical intraepithelial neoplasia to cervical cancer

İzzet Özgürlük, Haktan Bağış Erdem, Mustafa Tarık Alay, Okan Oktar, Firdevs Şahin-Duran, Ezgi Çevik‑Demir, Aysu Yeşim Tezcan, Hüseyin Levent Keskin
Article Number: 117
Published online on: 23 January 2026

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Case Report Open Access

Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Nobuhito Hara, Yumi Yoshii, Yoshiki Kojitani, Rika Sasaki, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Junichi Takemura, Ryo Miyata, Masatsugu Hamaji, Mitsuharu Hosono, Fumi Okada, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 116
Published online on: 22 January 2026

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Case Report Open Access

Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review

Danli Ye, Min Wu, Jiawen Zong, Weipeng Zeng, Guangning Yan, Juan Zhou, Wei Wang
Article Number: 115
Published online on: 20 January 2026

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Article Open Access

NDC80 kinetochore complex component is a potential molecular target of adenoid cystic carcinoma

Xia Yan, Sumei He, Yuansheng Lin, Jin Zhang, Jian Huan, Haibo Chen, Lina Lu
Article Number: 114
Published online on: 20 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑429 inhibits gastric cancer migration and invasion through the downregulation of specificity protein 1

Jingbin Ni, Yisha Yang, Di Liu, Hui Sun, Shimao Jin, Jingying Li
Article Number: 113
Published online on: 19 January 2026

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Review Open Access

Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome (Review)

Hanyue Ying, Ke Zhang, Yu Chen, Qinghua Deng, Chun Mao, Jiawei Li
Article Number: 112
Published online on: 19 January 2026

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Article Open Access

Endostar combined with docetaxel or cisplatin in the management of malignant ascites through hyperthermic intraperitoneal chemotherapy: A retrospective cohort study

Jing Wu, Dashan Yin, Jin Qian, Yi Zhou, Yajun Wu, Ganlu Zhang
Article Number: 111
Published online on: 14 January 2026

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Review

 Three‑dimensional culture of tumor cells (Review)

Shiyao Du, Jinyu Yang, Hui Li, Shanshan Men, Dongping Xu, Haifeng Wang
Article Number: 110
Published online on: 15 January 2026

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Article Open Access

Cytotoxic, apoptotic and genotoxic effects of thymoquinone‑oxime derivative on gastric cancer cells: An in vitro study

Kübra Bozali̇, Zeynep İnce, Nurhi̇lal Kiziltoprak, Taygun Gülşen, Mehmet Köstek, Yasi̇r Musa Kesgi̇n, Muhammer Ergenç, Mi̇ne Dağgez, Eren Altun, Fati̇h Taşkesen, Cebrai̇l Akyüz, Oğuzhan Sunamak, Mustafa Duman, Eray Meti̇n Güler
Article Number: 109
Published online on: 14 January 2026

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Review Open Access

Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review)

Zihe Guan, Lichao Han, Baojiang Chen, Yijia Ma, Qianyue Ni, Zijian Wang, Jingyu Yang, Zheng Liu
Article Number: 108
Published online on: 13 January 2026

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Article Open Access

Phosphorylated‑EGFR and MMP7 upregulation in gastric cancer: Association with metastasis and poor prognosis

Biran Ding, Yiqiu Wan, Yao Wu, Zhan Zhang, Ying Ma, Zuo Wang, Runqiu Jiang, Tao Li
Article Number: 107
Published online on: 14 January 2026

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Article Open Access

Study on the expression level of folate receptor γ in thyroid cancer and its association with clinicopathological characteristics

Jinying Cao, Yanxu Li, Xin Deng, Bo Lv, Ling Han, Ling Tong
Article Number: 106
Published online on: 12 January 2026

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Article Open Access

Prognostic value of glioma‑associated oncogene homolog 1 and SET domain‑containing protein 2 immunohistochemical scores in locally advanced cervical cancer

Erick De La Cruz‑Hernández, Gabriela Carolina Morales‑Sandoval, Marcela Lizano, Alejandro Avilés‑Salas, Leonardo Josué Castro‑Muñoz, Adela Carrillo‑García, Maria Del Pilar Ramos‑Godinez, Jaime Alberto Coronel‑Martinez, Adriana Contreras‑Paredes
Article Number: 105
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Clinical significance of bromodomain‑containing protein 7 and its association with tumor progression in prostate cancer

Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma
Article Number: 104
Published online on: 12 January 2026

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Article Open Access

LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance

Cairong Zhang, Jie Ma, Wenling Wang, Min Guo, Cuiliu Han, Madinamu Sadike, Kaichun Zhu
Article Number: 103
Published online on: 12 January 2026

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Article Open Access

Circular RNA hsa_circ_0006168: A potential biomarker for the diagnosis and prognosis of prostate cancer

Ye Ding, Mao-Tong Liu, Na Yu, Liusijie Gao, Li-Ping Chen
Article Number: 102
Published online on: 09 January 2026

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Article Open Access

Meta‑analysis of the clinical efficacy of anti‑PD‑1/L1 + paclitaxel/albumin‑paclitaxel + platinum vs. paclitaxel/albumin‑paclitaxel + platinum in the treatment of patients with advanced non‑small cell lung cancer

Feng Li, Suyun Yan, Liping Liu
Article Number: 101
Published online on: 09 January 2026

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Review Open Access

Progress in perioperative immunotherapy for lung cancer and analysis of therapy (Review)

Xiao Ma, Gaofeng Li, Heng Li, Lanjun Li, Hanting Zhao, Zhiqing Liu
Article Number: 100
Published online on: 09 January 2026

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Correction Open Access

[Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells

Xia Chen, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Yu Wang, Teng Ma, Bo Huang, Ping-Kun Zhou
Article Number: 99
Published online on: 08 January 2026

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Case Report Open Access

High‑intensity focused ultrasound in the multimodal treatment of colorectal cancer liver metastases: A case report

Yuanhong Yang, Hao Zhang, Yifan Shen, Fan Yang, Dan Zhao, Yujie Lin, Guohua Huang
Article Number: 98
Published online on: 07 January 2026

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Article Open Access

Exosomal microRNA‑448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis

Yuankun Chen, Tiantian Zhu, Fang Chen, Mingyue Niu, Haifeng Wu, Qiuping Wu, Zheng Wang, Wenting Li
Article Number: 97
Published online on: 07 January 2026

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Article

Diagnostic value of magnetic resonance imaging in preoperative evaluation of cervical cancer and analysis of pathological features

Xiaofei Cai, Xinjian Lu, Jinjun Yang, Xinxue Wei, Wenjing Yue, Yunqing Ban
Article Number: 96
Published online on: 07 January 2026

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Retraction Open Access

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk‑ChA‑1 and Mz‑ChA‑1 cell growth by inducing caspase‑dependent apoptosis and downregulation of survivin and Bcl‑2 expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li
Article Number: 95
Published online on: 07 January 2026

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Article Open Access

Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta‑analysis

Jiling Wang, Zheng Pan, Yongzheng Wang, Yanshuo Ye, Wei Li
Article Number: 94
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] miR‑185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma

Jinpeng He, Ning Tian, Yanli Yang, Liangliang Jin, Xiu Feng, Junrui Hua, Sulan Lin, Bing Wang, He Li, Jufang Wang
Article Number: 127
Published online on: 04 February 2026

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Review Open Access

Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen
Article Number: 126
Published online on: 03 February 2026

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Article Open Access

Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Review Open Access

Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Case Report Open Access

Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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