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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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January 2004 Volume 11 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January 2004 Volume 11 Issue 1

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Article

Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer

  • Authors:
    • Masaya Mukai
    • Shinkichi Sato
    • Hisao Nakasaki
    • Takayuki Tajima
    • Yuuki Saito
    • Noboru Nishiumi
    • Masayuki Iwasaki
    • Yutaka Tokuda
    • Kyoji Ogoshi
    • Hiroshi Inoue
    • Hiroyasu Makuuchi
  • View Affiliations / Copyright

    Affiliations: Tokai University Oiso Hospital, Department of Surgery, Kanagawa 259-0198, Japan. colorectalmasaya@yahoo.co.jp
  • Pages: 81-84
    |
    Published online on: January 1, 2004
       https://doi.org/10.3892/or.11.1.81
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Abstract

The correlation between detection of occult neo-plastic cells (ONCs) in lymph node sinuses and the recurrence/metastasis of primary breast, lung, esophageal, and gastric cancer was examined. Among patients with Stage I-III cancer treated by radical resection with dissection of at least 10 lymph nodes, 40 patients who suffered recurrence/metastasis within 5 years post-operatively and 94 patients who did not have recurrence within 5 years were randomly selected. A total of 1,340 lymph nodes were subjected to immunohistochemical staining for cytokeratin to identify ONCs. Then the sensitivity, specificity, positive predictive value, and negative predictive value of ONCs were determined for predicting the recurrence of each cancer. These parameters were respectively 40.0, 75.9, 62.4, and 55.8% for breast cancer, while the respective values were 50.0, 77.4, 68.9, and 60.8% for lung, 57.1, 64.3, 61.5, and 60.0% for esophageal, and 68.8, 65.0, 66.3, and 67.5% for gastric cancer. All of the parameters exceeded 65% for gastric cancer. ONCs also showed a high specificity for breast and lung cancer, but both the sensitivity and specificity were low for esophageal cancer.

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Copy and paste a formatted citation
Spandidos Publications style
Mukai M, Sato S, Nakasaki H, Tajima T, Saito Y, Nishiumi N, Iwasaki M, Tokuda Y, Ogoshi K, Inoue H, Inoue H, et al: Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer. Oncol Rep 11: 81-84, 2004.
APA
Mukai, M., Sato, S., Nakasaki, H., Tajima, T., Saito, Y., Nishiumi, N. ... Makuuchi, H. (2004). Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer. Oncology Reports, 11, 81-84. https://doi.org/10.3892/or.11.1.81
MLA
Mukai, M., Sato, S., Nakasaki, H., Tajima, T., Saito, Y., Nishiumi, N., Iwasaki, M., Tokuda, Y., Ogoshi, K., Inoue, H., Makuuchi, H."Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer". Oncology Reports 11.1 (2004): 81-84.
Chicago
Mukai, M., Sato, S., Nakasaki, H., Tajima, T., Saito, Y., Nishiumi, N., Iwasaki, M., Tokuda, Y., Ogoshi, K., Inoue, H., Makuuchi, H."Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer". Oncology Reports 11, no. 1 (2004): 81-84. https://doi.org/10.3892/or.11.1.81
Copy and paste a formatted citation
x
Spandidos Publications style
Mukai M, Sato S, Nakasaki H, Tajima T, Saito Y, Nishiumi N, Iwasaki M, Tokuda Y, Ogoshi K, Inoue H, Inoue H, et al: Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer. Oncol Rep 11: 81-84, 2004.
APA
Mukai, M., Sato, S., Nakasaki, H., Tajima, T., Saito, Y., Nishiumi, N. ... Makuuchi, H. (2004). Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer. Oncology Reports, 11, 81-84. https://doi.org/10.3892/or.11.1.81
MLA
Mukai, M., Sato, S., Nakasaki, H., Tajima, T., Saito, Y., Nishiumi, N., Iwasaki, M., Tokuda, Y., Ogoshi, K., Inoue, H., Makuuchi, H."Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer". Oncology Reports 11.1 (2004): 81-84.
Chicago
Mukai, M., Sato, S., Nakasaki, H., Tajima, T., Saito, Y., Nishiumi, N., Iwasaki, M., Tokuda, Y., Ogoshi, K., Inoue, H., Makuuchi, H."Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer". Oncology Reports 11, no. 1 (2004): 81-84. https://doi.org/10.3892/or.11.1.81
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