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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2004 Volume 11 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Alteration of the AT motif binding factor-1 expression in α-fetoprotein producing gastric cancer: Is it an event for differentiation and proliferation of the tumors?

Masao Iida, Johji Imura, Teruhito Furuichi, Toshio Sawada, Hirokazu Nagawa, Takahiro Fujimori
Pages: 3-7
Published online on: 01 January 2004

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Article

Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil

Makoto Tahara, Atsuhi Ochiai, Junya Fujimoto, Narikazu Boku, Wataru Yasui, Atsushi Ohtsu, Eiichi Tahara, Shigeaki Yoshida
Pages: 9-15
Published online on: 01 January 2004

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Article

Intratumoral genomic heterogeneity in primary head and neck cancer and corresponding metastases detected by dual-FISH

Karl Götte, Carsten Schäfer, Frank Riedel, Norbert Arens, Karl Hörmann
Pages: 17-23
Published online on: 01 January 2004

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Article

Akt2 expression correlates with prognosis of human hepatocellular carcinoma

Xundi Xu, Masato Sakon, Hiroaki Nagano, Nobuaki Hiraoka, Hirofumi Yamamoto, Nobuyasu Hayashi, Keizo Dono, Shoji Nakamori, Koji Umeshita, Yasuhiro Ito, Nariaki Matsuura, Morito Monden
Pages: 25-32
Published online on: 01 January 2004

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Article

Basic and clinical studies on quantitative analysis of lymph node micrometastasis in oral cancer

Akiko Onishi, Koh-Ichi Nakashiro, Mariko Mihara, Tomoki Sumida, Hitoshi Kawamata, Satoru Shintani, Tadateru Aida, Tetsuhiko Tachikawa, Hiroyuki Hamakawa
Pages: 33-39
Published online on: 01 January 2004

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Article

CD44 variant 6 expression predicts response to treatment in advanced colorectal cancer

R. Bendardaf, H. Lamlum, R. Ristamäki, S. Pyrhönen
Pages: 41-45
Published online on: 01 January 2004

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Article

Identification of lymphatic vessels in malignant, adenomatous and normal colonic mucosa using the novel immunostain D2-40

F. Fogt, R. L. Zimmerman, H. M. Ross, T. Daly, R. E. Gausas
Pages: 47-50
Published online on: 01 January 2004

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Article

Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions

Toru Amioka, Yasuhiko Kitadai, Toru Hiyama, Shinji Tanaka, Masaharu Yoshihara, Ken Haruma, Kazuaki Chayama
Pages: 51-55
Published online on: 01 January 2004

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Article

p53 expression and p21 expression are mutually exclusive in esophageal squamous cell carcinoma

Madoka Hamada, Yoshio Naomoto, Yasuhiro Shirakawa, Tomoki Yamatsuji, Kazuhiro Noma, Takayuki Motoki, Tetsuji Nobuhisa, Takaomi Okawa, Minoru Haisa, Mehmet Gunduz, Junji Matsuoka, Noriaki Tanaka
Pages: 57-63
Published online on: 01 January 2004

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Article

DPD activity and immunohistochemical DPD expression in human breast cancer

Jun Horiguchi, Takashi Yoshida, Yukio Koibuchi, Kotaro Iijima, Jun Ninomiya, Hiroyuki Takei, Takao Yokoe, Yuichi Iino, Yasuo Morishita
Pages: 65-72
Published online on: 01 January 2004

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Article

Gemcitabine suppresses malignant ascites of human pancreatic cancer: correlation with VEGF expression in ascites

Kenichi Kuwahara, Tamito Sasaki, Kensou Kobayashi, Bunjirou Noma, Masahiro Serikawa, Tomohiro Iiboshi, Hideki Miyata, Yukio Kuwada, Masateru Murakami, Souichirou Yamasaki, Kenji Kariya, Kenji Morinaka, Kazuaki Chayama
Pages: 73-80
Published online on: 01 January 2004

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Article

Occult neoplastic cells in the lymph node sinuses and recurrence of primary breast, lung, esophageal, and gastric cancer

Masaya Mukai, Shinkichi Sato, Hisao Nakasaki, Takayuki Tajima, Yuuki Saito, Noboru Nishiumi, Masayuki Iwasaki, Yutaka Tokuda, Kyoji Ogoshi, Hiroshi Inoue, Hiroyasu Makuuchi
Pages: 81-84
Published online on: 01 January 2004

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Article

Hot water soluble sesquiterpenes [anhydroperoxy-costunolide and 3-oxoeudesma-1,4(15),11(13)triene-12,6α-olide] isolated from laurel (Laurus nobilis L.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia cells

Takashi Komiya, Yayoi Yamada, Hiroyuki Moteki, Hirotaka Katsuzaki, Kunio Imai, Hiroshige Hibasami
Pages: 85-88
Published online on: 01 January 2004

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Case Report

Characterization of a highly aberrant plasma cell leukemia karyotype: A case report

Anita Heller, Hans-Joerg Fricke, Heike Starke, Ivan F. Loncarevic, Uwe Claussen, Thomas Liehr
Pages: 89-92
Published online on: 01 January 2004

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Article

Thalidomide prolongs disease stabilization after conventional therapy in patients with recurrent glioblastoma

Alessandro Morabito, Massimo Fanelli, Guido Carillio, Domenico Gattuso, Roberta Sarmiento, Giampietro Gasparini
Pages: 93-95
Published online on: 01 January 2004

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Article

Safety and efficacy of concurrent interstitial radiation and hyperthermia in the treatment of progressive malignant brain tumors

Prithvi Narayan, Ian Crocker, Eric Elder, Jeffrey J. Olson
Pages: 97-103
Published online on: 01 January 2004

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Article

Combination therapy with radiofrequency ablation and transcatheter chemoembolization for the treatment of hepatocellular carcinoma: Short-term recurrences and survival

Koichiro Yamakado, Atsuhiro Nakatsuka, Masao Akeboshi, Katsuya Shiraki, Takeshi Nakano, Kan Takeda
Pages: 105-109
Published online on: 01 January 2004

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Article

Role of surgery in local treatment of Ewing's sarcoma of the extremities in patients undergoing adjuvant and neoadjuvant chemotherapy

Gaetano Bacci, Stefano Ferrari, Alessandra Longhi, Davide Donati, Enza Barbieri, Cristiana Forni, Franco Bertoni, Marco Manfrini, Stefano Giacomini, Patrizia Bacchini
Pages: 111-120
Published online on: 01 January 2004

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Article

Nuclear accumulation of β-catenin without an additional somatic mutation in coding region of the APC gene in hepatoblastoma from a familial adenomatous polyposis patient

Takeshi Inukai, Keiji Furuuchi, Kanji Sugita, Kanako Uno, Akishi Ooi, Fumiaki Sasaki, Jun-Ichi Hamada, Tetsuya Moriuchi, Shinpei Nakazawa
Pages: 121-126
Published online on: 01 January 2004

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Article

Differential alternative splicing expressions of telomerase reverse transcriptase in gastrointestinal cell lines

Kumi Nagao, Kenji Katsumata, Yoshio Aizawa, Noboru Saito, Hiroyuki Hirata, Hiroshi Sasaki, Shigeki Yamamoto, Kazumasa Hikiji, Tsukasa Koiwa, Hisashi Hisatomi
Pages: 127-131
Published online on: 01 January 2004

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Article

Expression of the IAPs in multidrug resistant tumor cells

Monica Notarbartolo, Melchiorre Cervello, Paola Poma, Luisa Dusonchet, Maria Meli, Natale D'Alessandro
Pages: 133-136
Published online on: 01 January 2004

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Article

No evidence for mutation of B-RAF in urothelial carcinomas of the bladder and upper urinary tract

Robert Stoehr, Anke Brinkmann, Thomas Filbeck, Christoph Gamper, Peter Wild, Hagen Blaszyk, Ferdinand Hofstaedter, Ruth Knuechel, Arndt Hartmann
Pages: 137-141
Published online on: 01 January 2004

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Article

Surrounding muscle edema detected by MRI is valuable for diagnosis of intramuscular myxoma

Kazuto Nishimoto, Katsuyuki Kusuzaki, Akihiko Matsumine, Masashi Seto, Kazuo Fukutome, Masayuki Maeda, Satoshi Hosoi, Atsumasa Uchida
Pages: 143-148
Published online on: 01 January 2004

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Article

Efficacy of boron neutron capture therapy on liver metastases of colon adenocarcinoma: Optical and ultrastructural study in the rat

Rosanna Nano, Sergio Barni, Patrizia Chiari, Tazio Pinelli, Francesca Fossati, Saverio Altieri, Cecilia Zonta, Ubaldo Prati, Laura Roveda, Aris Zonta
Pages: 149-153
Published online on: 01 January 2004

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Article

Intratumoral injection of arsenic to enhance antitumor efficacy in human esophageal carcinoma cell xenografts

Zhong-Ying Shen, Yuan Zhang, Jiong-Yu Chen, Ming-Hua Chen, Jian Shen, Wen-Hong Luo, Yi Zeng
Pages: 155-159
Published online on: 01 January 2004

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Article

Role of v-Raf and truncated form RAF1 in the induction of vascular endothelial growth factor and vascularization

Maciej Malecki, Magdalena Seneta, Joanna Miloszewska, Halina Trembacz, Malgorzata Przybyszewska, Przemyslaw Janik
Pages: 161-165
Published online on: 01 January 2004

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Article

Combined treatment with selective cyclooxygenase-2 inhibitor and fluorinated pyrimidines for liver metastasis of colon cancer

Nobuo Matsunaga, Nobuya Yamada, Masaichi Ohira, Akiko Tachimori, Yukio Nishiguchi, Hiroji Nishino, Syuichi Seki, Kosei Hirakawa
Pages: 167-171
Published online on: 01 January 2004

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Article

A simple method for the simultaneous detection of E1A and E1B in adenovirus stocks

Erika Suzuki, Takehide Murata, Sanae Watanabe, Yukari Kujime, Megumi Hirose, Jianzhi Pan, Takahito Yamazaki, Hideyo Ugai, Kazunari K. Yokoyama
Pages: 173-178
Published online on: 01 January 2004

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Article

Expression of multidrug resistance-1 and multidrug resistance-associated protein genes in pediatric rhabdomyosarcoma

Soledad Gallego, Anna Llort, Andreu Parareda, José Sanchez de Toledo
Pages: 179-183
Published online on: 01 January 2004

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Article

Hypomagnesemia associated with chemotherapy in patients treated for acute lymphoblastic leukemia: Possible mechanisms

Chun-Yuan Guo, Jacqueline M. Halton, Ronald D. Barr, Stephanie A. Atkinson
Pages: 185-189
Published online on: 01 January 2004

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Article

N-/C-terminal deleted mutant of human endostatin efficiently acts as an anti-angiogenic and anti-tumorigenic agent

Heeyeong Cho, Woo Jean Kim, You Mie Lee, Young-Mi Kim, Young-Guen Kwon, Yong Suk Park, Eu-Yul Choi, Kyu-Won Kim
Pages: 191-195
Published online on: 01 January 2004

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Article

Association of serum IL-6 levels with comprehensive geriatric assessment variables in a population of elderly cancer patients

Giovanni Mantovani, Clelia Madeddu, Giulia Gramignano, Luca Ferreli, Elena Massa, Paolo Contu, Roberto Serpe
Pages: 197-206
Published online on: 01 January 2004

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Article

Chromosome 10 and 17 deletions and p53 gene mutations in Thai patients with astrocytomas

Supawadee Put-Ti-Noi, Songsak Petmitr, Voravut Chanyavanich, Tumtip Sangruji, Veerasak Theerapuncharoen, Kenshi Hayashi, Wipawan Thangnipon
Pages: 207-211
Published online on: 01 January 2004

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Article

Combined effect of aloe-emodin and chemotherapeutic agents on the proliferation of an adherent variant cell line of Merkel cell carcinoma

Eyal Fenig, Jardena Nordenberg, Einat Beery, Jaqueline Sulkes, Lina Wasserman
Pages: 213-217
Published online on: 01 January 2004

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Article

Androgen receptor versus erbB-1 and erbB-2 expression in human prostate neoplasms

Magdalena Brys, Magdalena Stawinska, Marek Foksinski, Andrzej Barecki, Cezary Zydek, Eugeniusz Miekos, Wanda M. Krajewska
Pages: 219-224
Published online on: 01 January 2004

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Article

Synergistic action of piroxicam on the eicosapentaenoic acid-induced apoptosis is associated with enhanced down-regulation of anti-apoptotic Bcl-2 expression but not promoted activation of pro-apoptotic Bid protein

Lawrence C.-M. Chiu, K.-F. Tong, Vincent E.C. Ooi
Pages: 225-230
Published online on: 01 January 2004

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Article

Alterations of transforming growth factor β receptor II, insulin growth factor receptor II genes in microsatellite unstable prostate carcinomas

Nandan Bhattacharyya, Jianming Tao, Eric A. Klein, Sipra Banerjee
Pages: 231-236
Published online on: 01 January 2004

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Article

Endovascular lung perfusion using high-dose cisplatin: Uptake and DNA adduct formation in an animal model

Daniel B. Brown, Margaret K. Ma, Richard J. Battafarano, Sailen Naidu, Dick Pluim, William C. Zamboni, Howard L. McLeod
Pages: 237-243
Published online on: 01 January 2004

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Article

Detection of telomerase RNA in the plasma of patients with breast cancer, malignant melanoma or thyroid cancer

Srdjan Novakovic, Marko Hocevar, Janez Zgajnar, Nikola Besic, Vida Stegel
Pages: 245-252
Published online on: 01 January 2004

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Article

Analysis of the RNA helicase A gene in human lung cancer

Xiao Wei, Manuela Pacyna-Gengelbach, Karsten Schlüns, Qian An, Yanning Gao, Shujun Cheng, Iver Petersen
Pages: 253-258
Published online on: 01 January 2004

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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