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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
September 2004 Volume 12 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September 2004 Volume 12 Issue 3

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Review

Advances for the treatment of primary central nervous system lymphoma (review)

  • Authors:
    • Ryuya Yamanaka
    • Ryuichi Tanaka

  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata City 951-8585, Japan. ryaman@bri.niigata-u.ac.jp
  • Pages: 563-568
    |
    Published online on: September 1, 2004
       https://doi.org/10.3892/or.12.3.563
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Abstract

Primary central nervous system lymphoma (PCNSL) is a non-Hodgkin's lymphoma arising in the CNS. This review will focus on the recent advances in the treatment of PCNSL. Combined methotrexate-based chemotherapy and radiation therapy is the standard treatment for PCNSL. A median overall survival of 40-60 months is obtained, however, neurotoxicity is a major problem. Preservation of cognitive function appears better after chemotherapy alone, therefore, there are increasing reports that radiotherapy is deferred after chemotherapy. At the moment, the findings of multicenter randomized trials should be awaited to clarify whether deferring radiotherapy in patients responding to chemotherapy allows them to maintain a better quality of life without increasing the risk of local recurrence. The well-designed, multicenter and randomized trials will elucidate the issues, such as best chemotherapy regimen, no brain irradiation in responder and second-line treatment.

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Copy and paste a formatted citation
Spandidos Publications style
Yamanaka R and Tanaka R: Advances for the treatment of primary central nervous system lymphoma (review). Oncol Rep 12: 563-568, 2004.
APA
Yamanaka, R., & Tanaka, R. (2004). Advances for the treatment of primary central nervous system lymphoma (review). Oncology Reports, 12, 563-568. https://doi.org/10.3892/or.12.3.563
MLA
Yamanaka, R., Tanaka, R."Advances for the treatment of primary central nervous system lymphoma (review)". Oncology Reports 12.3 (2004): 563-568.
Chicago
Yamanaka, R., Tanaka, R."Advances for the treatment of primary central nervous system lymphoma (review)". Oncology Reports 12, no. 3 (2004): 563-568. https://doi.org/10.3892/or.12.3.563
Copy and paste a formatted citation
x
Spandidos Publications style
Yamanaka R and Tanaka R: Advances for the treatment of primary central nervous system lymphoma (review). Oncol Rep 12: 563-568, 2004.
APA
Yamanaka, R., & Tanaka, R. (2004). Advances for the treatment of primary central nervous system lymphoma (review). Oncology Reports, 12, 563-568. https://doi.org/10.3892/or.12.3.563
MLA
Yamanaka, R., Tanaka, R."Advances for the treatment of primary central nervous system lymphoma (review)". Oncology Reports 12.3 (2004): 563-568.
Chicago
Yamanaka, R., Tanaka, R."Advances for the treatment of primary central nervous system lymphoma (review)". Oncology Reports 12, no. 3 (2004): 563-568. https://doi.org/10.3892/or.12.3.563
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