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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2004 Volume 12 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Expression of heat shock proteins in human hepatocellular carcinoma after radiofrequency ablation in an animal model

Gerd Schueller, Joachim Kettenbach, Roland Sedivy, Helga Bergmeister, Anton Stift, Josef Fried, Michael Gnant, Johannes Lammer
Pages: 495-499
Published online on: 01 September 2004

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Article

A novel tumor cell line cloned from mutated human embryonic bone marrow mesenchymal stem cells

Wenrong Xu, Hui Qian, Wei Zhu, Yongchang Chen, Qixiang Shao, Xiaochun Sun, Jiabo Hu, Chongxu Han, Xiran Zhang
Pages: 501-508
Published online on: 01 September 2004

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Article

Demethylating agent 5-aza-2'-deoxycytidine enhances expression of TNFRI and promotes TNF-mediated apoptosis in vitro and in vivo

Rafal Kaminski, Katarzyna Kozar, Justyna Niderla, Tomasz Grzela, Grzegorz Wilczynski, Janusz S. Skierski, Miroslawa Koronkiewicz, Marek Jakobisiak, Jakub Golab
Pages: 509-516
Published online on: 01 September 2004

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Article

Differential effects of raloxifene and tamoxifen on the expression of estrogen receptors and antigen Ki-67 in human endometrial adenocarcinoma cell line

Mariusz Koda, Katarzyna Jarzabek, Jozef Haczynski, Pawel Knapp, Stanislaw Sulkowski, Slawomir Wolczynski
Pages: 517-521
Published online on: 01 September 2004

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Article

Enhanced sensitivity of prostate cancer DU145 cells to cisplatinum by 5-aza-2'-deoxycytidine

Xiaolei Fang, Chengyun Zheng, Zhaoxu Liu, Peter Ekman, Dawei Xu
Pages: 523-526
Published online on: 01 September 2004

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Article

Inhibition of DNA methyltransferase by antisense oligodeoxynucleotide modifies cell characteristics in gastric cancer cell lines

Yoshiro Saikawa, Tetsuro Kubota, Shingo Maeda, Yoshihide Otani, Koichiro Kumai, Masaki Kitajima
Pages: 527-531
Published online on: 01 September 2004

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Article

Relation of E-cadherin and β-catenin expression to pit pattern in colorectal cancer

Motohiro Kojima, Akira Shiokawa, Nobuyuki Ohike, Yoshiro Tamegai, Hirotaka Kato, Toshio Morohoshi
Pages: 533-538
Published online on: 01 September 2004

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Article

Increased expression of thymidine phosphorylase in tumor tissue in proportion to TP-expression in primary normal tissue

Tsukasa Hotta, Katsutoshi Taniguchi, Yasuhito Kobayashi, Kiyofumi Johata, Masaki Sahara, Teiji Naka, Takashi Watanabe, Minoru Ochiai, Hiroshi Tanimura, Yukari T. Tsubota
Pages: 539-541
Published online on: 01 September 2004

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Article

Histology-specific gender, age and tumor-location distributions of Epstein-Barr virus-associated gastric carcinoma in Japan

Chihaya Koriyama, Suminori Akiba, Alejandro Corvalan, Edwin Carrascal, Tetsuhiko Itoh, Roberto Herrera-Goepfert, Yoshito Eizuru, Masayoshi Tokunaga
Pages: 543-547
Published online on: 01 September 2004

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Review

Pegylated liposomal doxorubicin: Pharmacologic and clinical evidence of potent antitumor activity with reduced anthracycline-induced cardiotoxicity (Review)

Michele Orditura, Fabiana Quaglia, Floriana Morgillo, Erika Martinelli, Eva Lieto, Giuseppe De Rosa, Daniela Comunale, Maria Rosaria Diadema, Fortunato Ciardiello, Giuseppe Catalano, Ferdinando De Vita
Pages: 549-556
Published online on: 01 September 2004

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Article

Sequence-dependence of cisplatin and 5-fluorouracil in advanced and recurrent gastric cancer

Wasaburo Koizumi, Minoru Kurihara, Koichi Hasegawa, Akimichi Chonan, Yasuhiko Kubo, Ryuichiro Maekawa, Ryozo Iwasaki, Tadashi Sasai, Yoshio Fukuyama, Kunitsugu Ishikawa, Kazuo Miyoshi, Koichi Yasutake, Makoto Hayakawa
Pages: 557-561
Published online on: 01 September 2004

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Review

Advances for the treatment of primary central nervous system lymphoma (review)

Ryuya Yamanaka, Ryuichi Tanaka
Pages: 563-568
Published online on: 01 September 2004

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Article

Hepatocellular carcinoma treated by percutaneous hot saline injection

Yoshio Araki, Miya Hukano, Mitsuyo Urabe, Tomoyuki Tsujikawa, Utako Yoshioka, Hisayuki Inoue, Yoshihide Hujiyama, Tadao Bamba
Pages: 569-571
Published online on: 01 September 2004

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Article

Comparison of effects of As2O3 and As4O6 on cell growth inhibition and gene expression profiles by cDNA microarray analysis in SiHa cells

Woong Shick Ahn, Su Mi Bae, Keun Ho Lee, Yong Wook Kim, Joon Mo Lee, Sung Eun Namkoong, Insu P. Lee, Chong Kook Kim, Jeong-Sun Seo, Jeong-Im Sin, Yong-Wan Kim
Pages: 573-580
Published online on: 01 September 2004

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Article

Prevention of irinotecan-induced diarrhoea by oral carbonaceous adsorbent (Kremezin™) in cancer patients

Yorinobu Maeda, Terumasa Ohune, Mamoru Nakamura, Miho Yamasaki, Yoshie Kiribayashi, Teruo Murakami
Pages: 581-585
Published online on: 01 September 2004

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Article

Relationship between HPV typing and the status of G2 cell cycle regulators in cervical neoplasia

Yasunori Hashiguchi, Hiroshi Tsuda, Sadako Nishimura, Takeshi Inoue, Naoki Kawamura, Kumio Yamamoto
Pages: 587-591
Published online on: 01 September 2004

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Article

Amplification/overexpression of Aurora-A in human gastric carcinoma: Potential role in differentiated type gastric carcinogenesis

Kiyoshi Kamada, Yukishige Yamada, Tomoko Hirao, Heisuke Fujimoto, Yasushi Takahama, Masatoh Ueno, Tomoyoshi Takayama, Akihiko Naito, Shuya Hirao, Yoshiyuki Nakajima
Pages: 593-599
Published online on: 01 September 2004

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Article

Prostate-related antigen-derived new peptides having the capacity of inducing prostate cancer-reactive CTLs in HLA-A2+ prostate cancer patients

Mamoru Harada, Satoko Matsueda, Akihisa Yao, Rika Ogata, Masanori Noguchi, Kyogo Itoh
Pages: 601-607
Published online on: 01 September 2004

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Article

Histologic tumor growth pattern is significantly associated with disease-related survival in muscle-invasive transitional cell carcinoma of the urinary bladder

Stefan Krüger, Frank Noack, Andreas Böhle, Alfred C. Feller
Pages: 609-613
Published online on: 01 September 2004

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Article

Cell growth after withdrawal of gefitinib (‘Iressa’, ZD1839) in human lung cancer cells

Hiroaki Satoh, Hiroichi Ishikawa, Mika Nakayama, Masachika Fujiwara, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 615-619
Published online on: 01 September 2004

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Article

Immunohistochemistry and microsatellite instability testing for selecting MLH1, MSH2 and MSH6 mutation carriers in hereditary non-polyposis colorectal cancer

Trinidad Caldés, Javier Godino, Ana Sanchez, Cesar Corbacho, Miguel De la Hoya, Jose Lopez Asenjo, Carmen Saez, Julian Sanz, Manuel Benito, Santiago Ramon Y Cajal, Eduardo Diaz-Rubio
Pages: 621-629
Published online on: 01 September 2004

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Article

Methylation of multiple genes in prostate cancer and the relationship with clinicopathological features of disease

Rakesh Singal, Larry Ferdinand, Isildinha M. Reis, James J. Schlesselman
Pages: 631-637
Published online on: 01 September 2004

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Article

Foscan®-based photodynamic treatment in vivo: correlation between efficacy and Foscan accumulation in tumor, plasma and leukocytes

Estelle Maugain, Siarhei Sasnouski, Vladimir Zorin, Jean-Louis Merlin, François Guillemin, Lina Bezdetnaya
Pages: 639-645
Published online on: 01 September 2004

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Article

Is survival following post-operative radiotherapy in pN1-non-small cell lung cancer reduced? Results of a multivariate analysis

Jochen Willner, Viktor Wiens, Manfred Jachmann, Imme Haubitz, Michael Flentje
Pages: 647-653
Published online on: 01 September 2004

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Article

Correlation of pre-operative coexistence of organ dysfunction with overall survival of patients with squamous cell carcinoma of the thoracic esophagus

Tadahiro Nozoe, Takahiro Ezaki, Ikuo Takahashi, Hideo Baba, Yoshihiko Maehara
Pages: 655-658
Published online on: 01 September 2004

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Article

Ganoderma lucidum spore extract inhibits endothelial and breast cancer cells in vitro

Qing-Yi Lu, Maryam R. Sartippour, Mai N. Brooks, Qifeng Zhang, Mary Hardy, Vay Liang Go, Frederick P. Li, David Heber
Pages: 659-662
Published online on: 01 September 2004

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Article

Deletion and aberrant CpG island methylation of Caspase 8 gene in medulloblastoma

Pilar Gonzalez-Gomez, M. J. Bello, M. M. Inda, M. E. Alonso, Dolores Arjona, Cinthia Amiñoso, Isabel Lopez-Marin, J. M. De Campos, J. L. Sarasa, J. S. Castresana, J. A. Rey
Pages: 663-666
Published online on: 01 September 2004

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Article

The human myotubularin-related protein suppresses the growth of lung carcinoma cells

Young Do Yoo, Sun Mi Cho, Jun Suk Kim, Yoon Soo Chang, Chul Min Ahn, Hyung Jung Kim
Pages: 667-671
Published online on: 01 September 2004

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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