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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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December 2004 Volume 12 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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December 2004 Volume 12 Issue 6

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Article

Methyl jasmonate induces apoptosis through induction of Bax/Bcl-Xs and activation of caspase-3 via ROS production in A549 cells

  • Authors:
    • Ji Hye Kim
    • Su Yeon Lee
    • Su Young Oh
    • Song Iy Han
    • Hye Gyeong Park
    • Mi-Ae Yoo
    • Ho Sung Kang

  • View Affiliations / Copyright

    Affiliations: Department of Molecular Biology, College of Natural Sciences, Pusan National University, Pusan 609-735, Korea
  • Pages: 1233-1238
    |
    Published online on: December 1, 2004
       https://doi.org/10.3892/or.12.6.1233
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Abstract

Jasmonates are plant lipid derivatives, similar to mammalian eicosanoid, that play a critical role(s) in plant defenses against herbivores and pathogens through up-regulating the expression of defense-related genes. Recently, jasmonates were shown to induce cell cycle arrest or apoptosis in human leukemia, prostate and breast cancer cells, but not in normal lymphocytes, suggesting that the chemicals can be used as a novel class of anti-cancer drugs. In the present study, we examined the molecular mechanism that contributes to methyl jasmonate-induced apoptosis. Herein we show that methyl jasmonate induces apoptosis through induction of Bax/Bcl-XS and activation of caspase-3 via reactive oxygen species production in A549 human lung adenocarcinoma cells.

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Copy and paste a formatted citation
Spandidos Publications style
Kim JH, Lee SY, Oh SY, Han SI, Park HG, Yoo M and Kang HS: Methyl jasmonate induces apoptosis through induction of Bax/Bcl-Xs and activation of caspase-3 via ROS production in A549 cells. Oncol Rep 12: 1233-1238, 2004.
APA
Kim, J.H., Lee, S.Y., Oh, S.Y., Han, S.I., Park, H.G., Yoo, M., & Kang, H.S. (2004). Methyl jasmonate induces apoptosis through induction of Bax/Bcl-Xs and activation of caspase-3 via ROS production in A549 cells. Oncology Reports, 12, 1233-1238. https://doi.org/10.3892/or.12.6.1233
MLA
Kim, J. H., Lee, S. Y., Oh, S. Y., Han, S. I., Park, H. G., Yoo, M., Kang, H. S."Methyl jasmonate induces apoptosis through induction of Bax/Bcl-Xs and activation of caspase-3 via ROS production in A549 cells". Oncology Reports 12.6 (2004): 1233-1238.
Chicago
Kim, J. H., Lee, S. Y., Oh, S. Y., Han, S. I., Park, H. G., Yoo, M., Kang, H. S."Methyl jasmonate induces apoptosis through induction of Bax/Bcl-Xs and activation of caspase-3 via ROS production in A549 cells". Oncology Reports 12, no. 6 (2004): 1233-1238. https://doi.org/10.3892/or.12.6.1233
Copy and paste a formatted citation
x
Spandidos Publications style
Kim JH, Lee SY, Oh SY, Han SI, Park HG, Yoo M and Kang HS: Methyl jasmonate induces apoptosis through induction of Bax/Bcl-Xs and activation of caspase-3 via ROS production in A549 cells. Oncol Rep 12: 1233-1238, 2004.
APA
Kim, J.H., Lee, S.Y., Oh, S.Y., Han, S.I., Park, H.G., Yoo, M., & Kang, H.S. (2004). Methyl jasmonate induces apoptosis through induction of Bax/Bcl-Xs and activation of caspase-3 via ROS production in A549 cells. Oncology Reports, 12, 1233-1238. https://doi.org/10.3892/or.12.6.1233
MLA
Kim, J. H., Lee, S. Y., Oh, S. Y., Han, S. I., Park, H. G., Yoo, M., Kang, H. S."Methyl jasmonate induces apoptosis through induction of Bax/Bcl-Xs and activation of caspase-3 via ROS production in A549 cells". Oncology Reports 12.6 (2004): 1233-1238.
Chicago
Kim, J. H., Lee, S. Y., Oh, S. Y., Han, S. I., Park, H. G., Yoo, M., Kang, H. S."Methyl jasmonate induces apoptosis through induction of Bax/Bcl-Xs and activation of caspase-3 via ROS production in A549 cells". Oncology Reports 12, no. 6 (2004): 1233-1238. https://doi.org/10.3892/or.12.6.1233
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