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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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December 2005 Volume 14 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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December 2005 Volume 14 Issue 6

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Review

Thiamin deficiency: A possible major cause of some tumors? (Review)

  • Authors:
    • Benjamin Y. Lee
    • Krishna Yanamandra
    • Joseph A. Bocchini

  • View Affiliations / Copyright

    Affiliations: Department of Pediatrics, Louisiana State University Health Sciences Center, 1501 Kings Hwy, Shreveport, LA 71130, USA. blee1@lsuhsc.edu
  • Pages: 1589-1592
    |
    Published online on: December 1, 2005
       https://doi.org/10.3892/or.14.6.1589
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Abstract

Based solely on clinical clues from a malnourished population, thiamin alone was intentionally and successfully injected to human cases with some tumors or masses. Two cases of submandibular gland cyst and 13 out of 15 cases of Baker's cyst were cured without recurrence for several decades. In a case with pathology-confirmed osteosarcoma, subcutaneous perfusion of thiamin HCl 300 once only reduced its circumference from 30 to 20 cm, equivalent to a reduction of 50-75% in volume, within 2 days. Current concepts on the role of thiamin in carcinogenesis are controversial. Some authors claimed that thiamin supported high rate of tumor cell survival, proliferation and chemotherapy resistance and suggested anti-thiamin therapy for cancer. On the other hand, some investigators have reported evidence of prevention of several varieties of cancers by dietary thiamin. A limited number of animal studies revealed evident relationship between thiamin deficiency and cancer development. Therefore, further study on the mechanism switching thiamin between cancer supporter and suppressor is needed.

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Copy and paste a formatted citation
Spandidos Publications style
Lee BY, Yanamandra K and Bocchini JA: Thiamin deficiency: A possible major cause of some tumors? (Review). Oncol Rep 14: 1589-1592, 2005.
APA
Lee, B.Y., Yanamandra, K., & Bocchini, J.A. (2005). Thiamin deficiency: A possible major cause of some tumors? (Review). Oncology Reports, 14, 1589-1592. https://doi.org/10.3892/or.14.6.1589
MLA
Lee, B. Y., Yanamandra, K., Bocchini, J. A."Thiamin deficiency: A possible major cause of some tumors? (Review)". Oncology Reports 14.6 (2005): 1589-1592.
Chicago
Lee, B. Y., Yanamandra, K., Bocchini, J. A."Thiamin deficiency: A possible major cause of some tumors? (Review)". Oncology Reports 14, no. 6 (2005): 1589-1592. https://doi.org/10.3892/or.14.6.1589
Copy and paste a formatted citation
x
Spandidos Publications style
Lee BY, Yanamandra K and Bocchini JA: Thiamin deficiency: A possible major cause of some tumors? (Review). Oncol Rep 14: 1589-1592, 2005.
APA
Lee, B.Y., Yanamandra, K., & Bocchini, J.A. (2005). Thiamin deficiency: A possible major cause of some tumors? (Review). Oncology Reports, 14, 1589-1592. https://doi.org/10.3892/or.14.6.1589
MLA
Lee, B. Y., Yanamandra, K., Bocchini, J. A."Thiamin deficiency: A possible major cause of some tumors? (Review)". Oncology Reports 14.6 (2005): 1589-1592.
Chicago
Lee, B. Y., Yanamandra, K., Bocchini, J. A."Thiamin deficiency: A possible major cause of some tumors? (Review)". Oncology Reports 14, no. 6 (2005): 1589-1592. https://doi.org/10.3892/or.14.6.1589
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