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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2005 Volume 14 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Anti-angiogenic effects of a nutrient mixture on human umbilical vein endothelial cells

M. Waheed Roomi, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 1399-1404
Published online on: 01 December 2005

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Article

Use of granulocyte colony-stimulating factor: A survey among Italian medical oncologists

Marco Danova, Giovanni Rosti, Sabino De Placido, Katia Bencardino, Marco Venturini
Pages: 1405-1412
Published online on: 01 December 2005

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Article

The expression of CD97EGF and its ligand CD55 on marginal epithelium is related to higher stage and depth of tumor invasion of gastric carcinomas

Yong Liu, Li Chen, Shuyou Peng, Zhouxun Chen, Oliver Gimm, Rainer Finke, Cuong Hoang-Vu
Pages: 1413-1420
Published online on: 01 December 2005

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Article

Radiosensitivity of hypoxic and proliferating clonogen in a human lung cancer grown in nude mice

Tadaaki Miyamoto, Sachiko Ishii, Kiyomi Eguchi-Kasai, Kumiko Koyama-Saegusa
Pages: 1421-1428
Published online on: 01 December 2005

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Article

Genomic alterations detected by comparative genomic hybridization in primary lung adenocarcinomas with special reference to the relationship with DNA ploidy

Masataro Hayashi, Shigeto Kawauchi, Kazuhiro Ueda, Yoshikazu Kaneda, Atsunori Oga, Tomoko Furuya, Kimikazu Hamano, Kohsuke Sasaki
Pages: 1429-1435
Published online on: 01 December 2005

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Article

Alterations and correlations of the components in the Wnt signaling pathway and its target genes in breast cancer

Shinji Ozaki, Satoshi Ikeda, Yasuyo Ishizaki, Takeshi Kurihara, Noriaki Tokumoto, Masahiko Iseki, Koji Arihiro, Tsuyoshi Kataoka, Mazazumi Okajima, Toshimasa Asahara
Pages: 1437-1443
Published online on: 01 December 2005

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Article

Plasminogen activator inhibitor-1 (PAI-1) gene transfection inhibits the liver metastasis of pancreatic cancer by preventing angiogenesis

Masafumi Inoue, Tetsuji Sawada, Yasutake Uchima, Kenjiro Kimura, Tamahiro Nishihara, Hiroaki Tanaka, Masakazu Yashiro, Nobuya Yamada, Masaichi Ohira, Kosei Hirakawa
Pages: 1445-1451
Published online on: 01 December 2005

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Article

Alterations of p53, cyclin D1 and pRB expression in the carcinogenesis of esophageal squamous cell carcinoma

H. Kawakubo, S. Ozawa, N. Ando, Y. Kitagawa, M. Mukai, M. Ueda, M. Kitajima
Pages: 1453-1459
Published online on: 01 December 2005

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Article

Cyclin B1 expression is an independent prognostic marker for poor outcome in diffuse large B-cell lymphoma

Ellen C. Obermann, Philip Went, Ann-Christine Pehrs, Alexandar Tzankov, Peter J. Wild, Stefano Pileri, Ferdinand Hofstaedter, Stephan Dirnhofer
Pages: 1461-1467
Published online on: 01 December 2005

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Article

Pathomorphological study on small nodular lesions in hepatitis C virus-related cirrhosis

Hisamitsu Miyaaki, Masaru Fujimoto, Mina Kurogi, Osamu Nakashima, Katsumi Eguchi, Masamichi Kojiro
Pages: 1469-1474
Published online on: 01 December 2005

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Article

Treatment with hydroxyurea and tyrphostin-1 significantly improves the transduction efficiency of recombinant adeno-associated viruses in human cancer cells

Sung Jin Kim, Young Ran Nam, Ohkyu Shin, Jene Choi, Boyoung Lee, Jin Woo Chang, Yunhee Kim Kwon, Keerang Park, Heuiran Lee
Pages: 1475-1479
Published online on: 01 December 2005

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Article

Exploration of genetic alterations in human endometrial cancer and melanoma: Distinct tumorigenic pathways that share a frequent abnormal PI3K/AKT cascade

Kazumi Ogawa, Chunlan Sun, Akira Horii
Pages: 1481-1485
Published online on: 01 December 2005

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Article

The influence of oral tumor cell proliferation activity and membrane potential on the transfection efficiency of a cationic liposome

Minoru Nakase, Kenya Okumura, Takahiko Kamei, Shinnosuke Nakamura, Madoka Inui, Toshiro Tagawa
Pages: 1487-1491
Published online on: 01 December 2005

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Article

S100A2 expression as a predictive marker for late cervical metastasis in stage I and II invasive squamous cell carcinoma of the oral cavity

Fumiyuki Suzuki, Nobuhiko Oridate, Akihiro Homma, Yuji Nakamaru, Tatsumi Nagahashi, Katsunori Yagi, Sanae Yamaguchi, Yasushi Furuta, Satoshi Fukuda
Pages: 1493-1498
Published online on: 01 December 2005

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Article

Glucose transporter-1 expression in the thyroid gland: Clinicopathological significance for papillary carcinoma

Masanori Yasuda, Naoki Ogane, Hiroyuki Hayashi, Yoichi Kameda, Yohei Miyagi, Tetsuji Iida, Yusuke Mori, Keiichi Tsukinoki, Takeo Minematsu, Yoshiyuki Osamura
Pages: 1499-1504
Published online on: 01 December 2005

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Article

Recurrence and 5-FU sensitivity of stage II/III node-positive gastric cancer with occult neoplastic cells in lymph node sinuses

Masaya Mukai, Takayuki Tajima, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Kazutoshi Tsuchiya, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1505-1510
Published online on: 01 December 2005

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Article

Two different global gene expression profiles in cancer cell lines established from etiologically different oral carcinomas

Merja Ruutu, Bo Johansson, Reidar Grenman, Stina Syrjänen
Pages: 1511-1517
Published online on: 01 December 2005

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Article

Up-regulation of PINCH in the stroma of oral squamous cell carcinoma predicts nodal metastasis

Jin-Ting Zhang, Qing-Xing Li, Dawei Wang, Zhen-Long Zhu, Yan-Hong Yang, Dong-Sheng Cui, Ming-Wei Wang, Xiao-Feng Sun
Pages: 1519-1522
Published online on: 01 December 2005

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Article

Inhibition of cytotoxicity of cisplatin by cyclooxygenase-2 inhibitor nimesulide in head and neck cancer cell lines

Cornelia Czembirek, Christina Eder-Czembirek, Boban M. Erovic, Dritan Turhani, Edgar Selzer, Dietmar Thurnher
Pages: 1523-1526
Published online on: 01 December 2005

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Article

Cell-cycle-associated markers and clinical outcome in human epithelial cancers: A tissue microarray study

I. Abdulkader, L. Sánchez, J. Cameselle-Teijeiro, F. Gude, J. E. Chávez, R. López-López, J. Forteza, M. Fraga
Pages: 1527-1531
Published online on: 01 December 2005

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Article

Disturbance of circadian gene expression in endometrial cancer: Detection by real-time quantitative RT-PCR

Hong-Chang Shih, Kong-Bung Choo, Tien-Jye Chang, Ming-Yu Yang, Mu-Chin Shih, Kun-Tu Yeh, Ta-Chih Liu, Shung-Feng Lin, Jan-Gowth Chang
Pages: 1533-1538
Published online on: 01 December 2005

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Article

First-line systemic treatment with gefitinib in stage IV non-small cell lung cancer

Tobias Lange, Carsten Müller-Tidow, Hubert Serve, Petra Hoffknecht, Wolfgang E. Berdel, Michael Thomas
Pages: 1539-1542
Published online on: 01 December 2005

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Article

Combination hepatic arterial infusion therapy is effective for ocular melanoma metastasis to the liver

Hiroki Ueda, Hiroko Hamagami, Hiroto Tanaka, Yohei Kida, Masakazu Ichinose
Pages: 1543-1546
Published online on: 01 December 2005

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Article

Topotecan plus ifosfamide in patients with platinum refractory advanced/metastatic non-small cell lung cancer: A phase II trial

Vito Lorusso, Vittorio Gebbia, Massimiliano Spada, Michele Guida, Grazia Cassano, Cosimo Brunetti, Domenico Germano, Giuseppe Nettis, Giovanni Izzi, Domenico Galetta, Marianna Giampaglia, Nicola Silvestris, Giuseppe Colucci
Pages: 1547-1551
Published online on: 01 December 2005

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Article

Nicotine induces chromatin changes and c-Jun up-regulation in HL-60 leukemia cells

Emilie Landais, Victoria El-Khoury, Alain Prevost, Jean Dufer, Françoise Liautaud-Roger
Pages: 1553-1558
Published online on: 01 December 2005

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Article

Decrease in size of azoxymethane induced colon carcinoma in F344 rats by 180-day fermented miso

Yoshie Ohuchi, Yuki Myojin, Fumio Shimamoto, Naoki Kashimoto, Kenji Kamiya, Hiromitsu Watanabe
Pages: 1559-1564
Published online on: 01 December 2005

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Article

Vascular endothelial growth factor and soluble FLT-1 receptor interactions and biological implications

Maciej Malecki, Halina Trembacz, Bozena Szaniawska, Malgorzata Przybyszewska, Przemyslaw Janik
Pages: 1565-1569
Published online on: 01 December 2005

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Article

Improved survival using multi-modality therapy in patients with lung metastases from colorectal cancer: A preliminary study

Yasuhiro Inoue, Chikao Miki, Junichiro Hiro, Eiki Ojima, Koichiro Yamakado, Kan Takeda, Masato Kusunoki
Pages: 1571-1576
Published online on: 01 December 2005

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Article

Complex formations involving both SP-1 and SP-3 at the transcriptional regulatory sequence correlate with the activation of the Keratin 14 gene in human oral squamous cell carcinoma cells

Shuri Ohkura, Nobuo Kondoh, Akiyuki Hada, Masaaki Arai, Yutaka Yamazaki, Masanobu Sindoh, Masayuki Takahashi, Isamu Matsumoto, Mikio Yamamoto
Pages: 1577-1581
Published online on: 01 December 2005

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Review

WNT/PCP signaling pathway and human cancer (Review)

Masaru Katoh
Pages: 1583-1588
Published online on: 01 December 2005

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Review

Thiamin deficiency: A possible major cause of some tumors? (Review)

Benjamin Y. Lee, Krishna Yanamandra, Joseph A. Bocchini
Pages: 1589-1592
Published online on: 01 December 2005

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Review

The role of serotonin in tumour growth (Review)

Emad J. Siddiqui, Cecil S. Thompson, Dimitri P. Mikhailidis, Faiz H. Mumtaz
Pages: 1593-1597
Published online on: 01 December 2005

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Article

Artesunate in the treatment of metastatic uveal melanoma - first experiences

Thomas G. Berger, Detlef Dieckmann, Thomas Efferth, Erwin S. Schultz, Jens-Oliver Funk, Andreas Baur, Gerold Schuler
Pages: 1599-1603
Published online on: 01 December 2005

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Article

Demographic and psychosocial factors associated with risk perception for breast cancer

Uwe G. Pöhls, Peter A. Fasching, Heike Beck, Manfred Kaufmann, Marion Kiechle, Gunther von Minckwitz, Stefan Paepke, Beate Schultz-Zehden, Ulrike Schwarz-Boeger, Matthias W. Beckmann
Pages: 1605-1613
Published online on: 01 December 2005

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Article

Down-regulation of PEDF expression by ribozyme transgene in endothelial and lung cancer cells and its impact on angiogenesis in vitro

Lijian Zhang, Jinfeng Chen, Yang Ke, Robert E. Mansel, Wen G. Jiang
Pages: 1615-1619
Published online on: 01 December 2005

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Article

Aberrant methylation: common in thymic carcinomas, rare in thymomas

Makoto Suzuki, Hong Chen, Hisayuki Shigematsu, Soichiro Ando, Tomohiko Iida, Takahiro Nakajima, Takehiko Fujisawa, Hideki Kimura
Pages: 1621-1624
Published online on: 01 December 2005

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Article

Preventive effect of the soluble tumor-associated antigens on DMBA induced tumorigenesis in C3H/He mice

George Kossoy, Herzl Ben-Hur, Asher Elhayany, David F. Schneider, Nadja Kossoy, Itshak Zusman
Pages: 1625-1629
Published online on: 01 December 2005

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Article

Radical radiotherapy alone for glomus jugulare and tympanicum tumours

Laura Shelley Pemberton, Ric Swindell, Andrew John Sykes
Pages: 1631-1633
Published online on: 01 December 2005

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Article

The proteasome inhibitor MG132 induces apoptosis in human pancreatic cancer cells

Moritz N. Wente, Guido Eibl, Howard A. Reber, Helmut Friess, Markus W. Büchler, Oscar J. Hines
Pages: 1635-1638
Published online on: 01 December 2005

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Article

A novel region of deletion on 13q33-q34 in esophageal squamous cell carcinoma

Guang-Ming Guo, Xiao-Ping Huang, Jin-Tang Dong, Yan Caia, Xin Xu, Ya-Ling Han, Min Wu, Qi-Min Zhan, Ming-Rong Wang
Pages: 1639-1646
Published online on: 01 December 2005

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Article

Thoracic radiation therapy and concomitant low-dose daily paclitaxel in non-small cell lung cancer: A phase I study

Carlo Gobitti, Giovanni Franchin, Emilio Minatel, Marco Gigante, Barbara Basso, Laurentiu Bujor, Mauro G. Trovò
Pages: 1647-1653
Published online on: 01 December 2005

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Article

Expression and prognostic value of EGFR in invasive breast cancer

I. Quintela, M. D. Corte, M. T. Allende, J. Vazquez, J. C. Rodríguez, M. Bongera, M. Lamelas, L. O. Gonzalez, A. Vega, J. L. García-Muñiz, A. Astudillo, F. Vizoso
Pages: 1655-1663
Published online on: 01 December 2005

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Article

Analysis of tumor progression by transcriptional profiling of mouse MK16 cell lines transformed with human papillomavirus type 16 E6 and E7 oncogenes and activated H-ras

Michal Smahel, Jana Smahelová, Pavla Tejklová, Ruth Tachezy, Frantisek Jelínek
Pages: 1665-1674
Published online on: 01 December 2005

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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