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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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May 2006 Volume 15 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May 2006 Volume 15 Issue 5

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Article

A new tool for experimental tumour research

  • Authors:
    • Chengwen Zhang
    • Nikolaus Gassler
    • Philipp A. Schnabel
    • Hendrik Dienemann
    • Armin Kolb
    • Peter Buchler
    • Markus Buchler
    • Helmut Friess
    • Ingrid Herr

  • View Affiliations / Copyright

    Affiliations: Molecular Urooncology, German Cancer Research Center, University of Heidelberg, Heidelberg, Germany
  • Pages: 1153-1155
    |
    Published online on: May 1, 2006
       https://doi.org/10.3892/or.15.5.1153
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Abstract

Surgical resected tumours are often stored for hours in the clinic upon transfer to the bench leading to apoptosis of tumour cells making them no longer suitable for molecular analysis and diagnostic procedures. The way out of this problem may be a new oxygen-enriched solution (OES). We tested this agent using surgical resections of carcinomas of lung, rectum and pancreas. Immediately after resection, one part of each individual tumour was stored in PBS and the other part in OES, and the content of viable or dead cells was determined by trypan blue exclusion and MTT-assay. We found that OES keeps tumour cells up to 3 days and longer more viable than PBS and reduces the percentage of dead cells without inducing therapy resistance and affecting the outcome of experimental procedures. Thus, storing freshly resected tumours in OES may save time for tumour transfer and initiation of experiments.

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Copy and paste a formatted citation
Spandidos Publications style
Zhang C, Gassler N, Schnabel PA, Dienemann H, Kolb A, Buchler P, Buchler M, Friess H and Herr I: A new tool for experimental tumour research. Oncol Rep 15: 1153-1155, 2006.
APA
Zhang, C., Gassler, N., Schnabel, P.A., Dienemann, H., Kolb, A., Buchler, P. ... Herr, I. (2006). A new tool for experimental tumour research. Oncology Reports, 15, 1153-1155. https://doi.org/10.3892/or.15.5.1153
MLA
Zhang, C., Gassler, N., Schnabel, P. A., Dienemann, H., Kolb, A., Buchler, P., Buchler, M., Friess, H., Herr, I."A new tool for experimental tumour research". Oncology Reports 15.5 (2006): 1153-1155.
Chicago
Zhang, C., Gassler, N., Schnabel, P. A., Dienemann, H., Kolb, A., Buchler, P., Buchler, M., Friess, H., Herr, I."A new tool for experimental tumour research". Oncology Reports 15, no. 5 (2006): 1153-1155. https://doi.org/10.3892/or.15.5.1153
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang C, Gassler N, Schnabel PA, Dienemann H, Kolb A, Buchler P, Buchler M, Friess H and Herr I: A new tool for experimental tumour research. Oncol Rep 15: 1153-1155, 2006.
APA
Zhang, C., Gassler, N., Schnabel, P.A., Dienemann, H., Kolb, A., Buchler, P. ... Herr, I. (2006). A new tool for experimental tumour research. Oncology Reports, 15, 1153-1155. https://doi.org/10.3892/or.15.5.1153
MLA
Zhang, C., Gassler, N., Schnabel, P. A., Dienemann, H., Kolb, A., Buchler, P., Buchler, M., Friess, H., Herr, I."A new tool for experimental tumour research". Oncology Reports 15.5 (2006): 1153-1155.
Chicago
Zhang, C., Gassler, N., Schnabel, P. A., Dienemann, H., Kolb, A., Buchler, P., Buchler, M., Friess, H., Herr, I."A new tool for experimental tumour research". Oncology Reports 15, no. 5 (2006): 1153-1155. https://doi.org/10.3892/or.15.5.1153
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