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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2006 Volume 15 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

The expression of vascular endothelial growth factor determines the efficacy of post-operative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer

Yutaka Ogata, Keiko Matono, Tomoaki Mizobe, Nobuya Ishibashi, Shinjiro Mori, Yoshito Akagi, Satoru Ikeda, Hiroyuki Ozasa, Hidetsugu Murakami, Kazuo Shirouzu
Pages: 1111-1116
Published online on: 01 May 2006

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Article

Anti-apoptotic N-cadherin signaling and its prognostic implication in human hepatocellular carcinomas

Geum-Youn Gwak, Jung-Hwan Yoon, Su Jong Yu, Su Cheol Park, Ja June Jang, Kyoung Bun Lee, Sung-Hee Lee, Soo-Mi Lee, Chan Soo Shin, Kyung-Suk Suh, Hyo-Suk Lee
Pages: 1117-1123
Published online on: 01 May 2006

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Article

E-cadherin and DAP kinase in pancreatic adenocarcinoma and corresponding lymph node metastases

Temuujin Dansranjavin, Christian Möbius, Andrea Tannapfel, Michael Bartels, Christian Wittekind, Johan Hauss, Helmut Witzigmann
Pages: 1125-1131
Published online on: 01 May 2006

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Article

Anti-tumor effects of herbal medicines on endometrial carcinomas via estrogen receptor-α-related mechanism

Zenglin Lian, Kenji Niwa, Kyoko Onogi, Hideki Mori, Rosanne C. Harrigan, Teruhiko Tamaya
Pages: 1133-1136
Published online on: 01 May 2006

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Article

Glucocorticosteroid receptors in ovarian carcinomas

Joachim Woenckhaus, Folker E. Franke, Andreas Hackethal, Richard Von Georgi, Karsten Münstedt
Pages: 1137-1140
Published online on: 01 May 2006

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Article

Recurrent NMYC copy number gain and high protein expression in basal cell carcinoma

Kolja Freier, Christa Flechtenmacher, Frauke Devens, Wolfgang Hartschuh, Christof Hofele, Peter Lichter, Stefan Joos
Pages: 1141-1145
Published online on: 01 May 2006

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Article

The effect of RhoA on human umbilical vein endothelial cell migration and angiogenesis in vitro

Liangping Zhao, Gang Xu, Jianfeng Zhou, Hui Xing, Shixuan Wang, Mingfu Wu, Yun Ping Lu, Ding Ma
Pages: 1147-1152
Published online on: 01 May 2006

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Article

A new tool for experimental tumour research

Chengwen Zhang, Nikolaus Gassler, Philipp A. Schnabel, Hendrik Dienemann, Armin Kolb, Peter Buchler, Markus Buchler, Helmut Friess, Ingrid Herr
Pages: 1153-1155
Published online on: 01 May 2006

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Article

Expression of gastric mucin MUC5AC and gastric transcription factor SOX2 in ampulla of vater adenocarcinoma: Comparison between expression patterns and histologic subtypes

Yuichi Sanada, Kazuhiro Yoshida, Kazuo Konishi, Mamoru Oeda, Masahiro Ohara, Yasuhiro Tsutani
Pages: 1157-1161
Published online on: 01 May 2006

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Article

Antiangiogenic agent, thalidomide increases the antitumor effect of single high dose irradiation (gamma knife radiosurgery) in the rat orthotopic glioma model

Jung-Il Lee, Satoshi Itasaka, Ji Tae Kim, Do-Hyun Nam
Pages: 1163-1168
Published online on: 01 May 2006

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Article

Preventive effects of chrysin on the development of azoxymethane-induced colonic aberrant crypt foci in rats

Shingo Miyamoto, Hiroyuki Kohno, Rikako Suzuki, Shigeyuki Sugie, Akira Murakami, Hajime Ohigashi, Takuji Tanaka
Pages: 1169-1173
Published online on: 01 May 2006

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Article

Cellular components involved in the cell death induced by cisplatin in the absence of p53 activation

In Hwa Bae, Sung Wook Kang, Sung Hwan Yoon, Hong-Duck Um
Pages: 1175-1180
Published online on: 01 May 2006

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Article

Expression profile of N-cadherin differs from other classical cadherins as a prognostic marker in renal cell carcinoma

Toru Shimazui, Takahiro Kojima, Mizuki Onozawa, Masahiko Suzuki, Taeko Asano, Hideyuki Akaza
Pages: 1181-1184
Published online on: 01 May 2006

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Article

Long-term survival and tumor 5-FU sensitivity in patients with stage IV colorectal cancer and peritoneal dissemination

Sayuri Hasegawa, Masaya Mukai, Shinkichi Sato, Hiromi Ninomiya, Kanako Wakui, Nobukazu Komatsu, Takayuki Tajima, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1185-1190
Published online on: 01 May 2006

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Article

The regulatory effect of tamoxifen on fibronectin expression in estrogen-dependent MCF-7 breast carcinoma cells

Yoshio Horii, Hiroyuki Takei, Yukio Koibuchi, Jun Horiguchi, Michio Maemura, Yuichi Iino, Yasuo Morishita
Pages: 1191-1195
Published online on: 01 May 2006

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Article

Expression of CD137 and CD137 ligand in colorectal cancer patients

Jan Dimberg, Anders Hugander, Dick Wågsäter
Pages: 1197-1200
Published online on: 01 May 2006

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Article

Liposomal cisplatin combined with gemcitabine in pretreated advanced pancreatic cancer patients: A phase I-II study

George P. Stathopoulos, Teni Boulikas, Maria Vougiouka, Sotirios K. Rigatos, John G. Stathopoulos
Pages: 1201-1204
Published online on: 01 May 2006

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Article

Mutations of the epidermal growth factor receptor gene in gastrointestinal tract tumor cell lines

Toshimoto Kimura, Chihaya Maesawa, Kenichiro Ikeda, Go Wakabayashi, Tomoyuki Masuda
Pages: 1205-1210
Published online on: 01 May 2006

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Article

Construction and characterization of a novel fusion protein consisting of anti-CD3 antibody fused to recombinant interleukin-2

Kuan-Der Lee, Hsin-Wei Chen, Chih-Cheng Chen, Yan-Chung Shih, Hsing-Kun Liu, Mei-Lien Cheng
Pages: 1211-1216
Published online on: 01 May 2006

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Article

Possible predictive markers related to micro-metastasis in breast cancer patients

Li Zhu, Wings T.Y. Loo, Carter W.N. Cheng, Louis W.C. Chow
Pages: 1217-1223
Published online on: 01 May 2006

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Article

Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells

Cheol Park, Gi Young Kim, Gun Do Kim, Byung Tae Choi, Yeong-Min Park, Yung Hyun Choi
Pages: 1225-1231
Published online on: 01 May 2006

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Article

High rate of molecular alteration in histologically tumour-free bronchial epithelium of NSCLC patients detected by multicolour fluorescence in situ hybridisation

Wolfgang Hilbe, Jutta Auberger, Stephan Dirnhofer, Thomas Schmid, Martin Erdel, Hans-Christoph Duba
Pages: 1233-1240
Published online on: 01 May 2006

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Article

DNA cytosine methylation profile in various cancer-related genes is altered in cultured rat hepatocyte cell lines as compared with primary hepatocytes

Kiyoshi Asada, Rumiko Asada, Hitoshi Yoshiji, Hiroshi Fukui, Robert A. Floyd, Yashige Kotake
Pages: 1241-1248
Published online on: 01 May 2006

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Article

Differential expression of alternatively spliced mRNA forms of the insulin-like growth factor 1 receptor in human neuroendocrine tumors

Lorenza Vitale, Luca Lenzi, Shane A. Huntsman, Silvia Canaider, Flavia Frabetti, Raffaella Casadei, Federica Facchin, Paolo Carinci, Maria Zannotti, Domenico Coppola, Pierluigi Strippoli
Pages: 1249-1256
Published online on: 01 May 2006

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Article

Gene mutation analysis of sinonasal lymphomas in Indonesia

Antonius Nikolas Kurniawan, Tadashi Hongyo, Endang S.R. Hardjolukito, Maria Francisca Ham, Tetsuya Takakuwa, Ria Kodariah, Yoshihiko Hoshida, Taisei Nomura, Katsuyuki Aozasa
Pages: 1257-1263
Published online on: 01 May 2006

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Article

Gene expression profiles with cDNA microarray reveal RhoGDI as a predictive marker for paclitaxel resistance in ovarian cancers

Tomoko Goto, Masashi Takano, Masaru Sakamoto, Ayako Kondo, Junko Hirata, Tsunekazu Kita, Hitoshi Tsuda, Yoshio Tenjin, Yoshihiro Kikuchi
Pages: 1265-1271
Published online on: 01 May 2006

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Article

Anticancer effects of low-dose 10-hydroxycamptothecin in human colon cancer

Yueh-Hsin Ping, Hsin-Chen Lee, Jen-Yi Lee, Pin-Ho Wu, Li-Kang Ho, Chin-Wen Chi, Ming-Fong Lu, Jane-Jen Wang
Pages: 1273-1279
Published online on: 01 May 2006

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Article

Aberrant methylation of RASGRF2 and RASSF1A in human non-small cell lung cancer

Hong Chen, Makoto Suzuki, Yohko Nakamura, Miki Ohira, Soichiro Ando, Tomohiko Iida, Takahiro Nakajima, Akira Nakagawara, Hideki Kimura
Pages: 1281-1285
Published online on: 01 May 2006

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Article

Selectively enhanced radiation sensitivity in prostate cancer cells associated with proteasome inhibition

Graham Warren, Kris Grimes, Yong Xu, Mahesh Kudrimoti, William St. Clair
Pages: 1287-1291
Published online on: 01 May 2006

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Article

hRFI overexpressed in HCT116 cells modulates Bcl-2 family proteins when treated with 5-fluorouracil

Shin Sasaki, Toshiaki Watanabe, Takashi Kobunai, Tsuyoshi Konishi, Hideki Nagase, Yoshikazu Sugimoto, Toshinori Oka, Hirokazu Nagawa
Pages: 1293-1298
Published online on: 01 May 2006

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Article

Analysis of ribonucleotide reductase M2 mRNA levels in patient samples after GTI-2040 antisense drug treatment

Agnes Juhasz, Aikaterini Vassilakos, Helen K. Chew, David Gandara, Yun Yen
Pages: 1299-1304
Published online on: 01 May 2006

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Article

Analysis of interleukin (IL)-1β IL-1 receptor antagonist, soluble IL-1 receptor type II and IL-1 accessory protein in HCV-associated lymphoproliferative disorders

Massimo Libra, Katia Mangano, Massimiliano Anzaldi, Cinzia Quattrocchi, Marco Donia, Roberto Di Marco, Santo Signorelli, Guido Scalia, Anna L. Zignego, Valli De Re, Maria C. Mazzarino, Ferdinando Nicoletti
Pages: 1305-1308
Published online on: 01 May 2006

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Article

Is neuroendocrine cell differentiation detected using chromogranin A from patients with bone metastatic prostate cancer a prognostic factor for outcome?

Yoshiaki Yamada, Kogenta Nakamura, Shigeyuki Aoki, Tomohiro Taki, Hiroyuki Matsubara, Shotoku Sai, Katsuya Naruse, Motoi Tobiume, Remi Katsuda, Kenji Zennami, Nobuaki Honda, Atsuko Nakagawa, Hiroshi Ikeda
Pages: 1309-1313
Published online on: 01 May 2006

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Article

Expression of Foxp3 in non-small cell lung cancer patients is significantly higher in tumor tissues than in normal tissues, especially in tumors smaller than 30 mm

Yasunori Ishibashi, Shigebumi Tanaka, Kohei Tajima, Takeshi Yoshida, Hiroyuki Kuwano
Pages: 1315-1319
Published online on: 01 May 2006

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Article

Urinary gelatinase activities (matrix metalloproteinases 2 and 9) in human bladder tumors

Angelina Di Carlo, Daniela Terracciano, Angela Mariano, Vincenzo Macchia
Pages: 1321-1326
Published online on: 01 May 2006

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Article

Effects of extracts from two Native American plants on proliferation of human breast and colon cancer cell lines in vitro

Amber L. Daniels, Severine Van Slambrouck, Robin K. Lee, Tammy S. Arguello, James Browning, Michael J. Pullin, Alexander Kornienko, Wim F.A. Steelant
Pages: 1327-1331
Published online on: 01 May 2006

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Article

In vivo growth of transitional and renal cell carcinoma cell lines can be suppressed by the adenovirus-mediated expression of a soluble form of vascular endothelial growth factor receptor

Haruhiko Ichikura, Masatoshi Eto, Hikaru Ueno, Mamoru Harada, Koichi Takayama, Noriaki Tokuda, Katsunori Tatsugami, Seiji Naito
Pages: 1333-1337
Published online on: 01 May 2006

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Article

Relationships between dynamic contrast-enhanced MRI findings and pattern of invasion for tongue carcinoma

Yasunori Ariyoshi, Masashi Shimahara
Pages: 1339-1343
Published online on: 01 May 2006

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Article

Increased tolerability of bimonthly 12-hour timed flat infusion 5-fluorouracil/irinotecan regimen in advanced colorectal cancer: A dose-finding study

C. Ficorella, E. Ricevuto, M. F. Morelli, R. Morese, K. Cannita, G. Cianci, G. Porzio, Z. C. Di Rocco, F. De Galitiis, M. De Tursi, N. Tinari, S. Iacobelli, P. Marchetti
Pages: 1345-1350
Published online on: 01 May 2006

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Article

Changes in bone resorption and vascular endothelial growth factor after a single zoledronic acid infusion in cancer patients with bone metastases from solid tumours

Daniele Santini, Bruno Vincenzi, Rosemary A. Hannon, Janet E. Brown, Giordano Dicuonzo, Silvia Angeletti, Annalisa La Cesa, Robert E. Coleman, Giuseppe Tonini, Alfredo Budillon, Michele Caraglia, Ingunn Holen
Pages: 1351-1357
Published online on: 01 May 2006

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Article

Inhibition of Src activity enhances the tumor-suppressive effect of the connexin 32 gene in Caki-1 renal cancer cells

Eriko Fujimoto, Hiromi Sato, Sumiko Shirai, Yoji Nagashima, Nantiga Virgona, Kiyokazu Hagiwara, Hiroshi Yamasaki, Etsuko Negishi, Koichi Ueno, Tomohiro Yano
Pages: 1359-1365
Published online on: 01 May 2006

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Article

Plasma proteomic profiling: Search for lung cancer diagnostic and early detection markers

Iqbal Unnisa Ali, Zhen Xiao, Winfred Malone, Mylinh Smith, Thomas P. Conrads, Timothy D. Veenstra, Peter Greenwald, Brian T. Luke, Jerry W. McLarty
Pages: 1367-1372
Published online on: 01 May 2006

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Article

Application of intrathecal trastuzumab (Herceptin™) for treatment of meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer

H. J. Stemmler, M. Schmitt, N. Harbeck, A. Willems, H. Bernhard, D. Lässig, S. Schoenberg, V. Heinemann
Pages: 1373-1377
Published online on: 01 May 2006

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Article

In situ gene expression and localization of metalloproteinases MMP1, MMP2, MMP3, MMP9, and their inhibitors TIMP1 and TIMP2 in human renal cell carcinoma

Venugopal Bhuvarahamurthy, Glen O. Kristiansen, Manfred Johannsen, Stefan A. Loening, Dietmar Schnorr, Klaus Jung, Andrea Staack
Pages: 1379-1384
Published online on: 01 May 2006

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Article

Lactoferricin-induced apoptosis in estrogen-nonresponsive MDA-MB-435 breast cancer cells is enhanced by C6 ceramide or tamoxifen

Suzanne J. Furlong, Jamie S. Mader, David W. Hoskin
Pages: 1385-1390
Published online on: 01 May 2006

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Article

Comparative integromics on Ephrin family

Yuriko Katoh, Masaru Katoh
Pages: 1391-1395
Published online on: 01 May 2006

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Article

Significant overexpression of SPARC/osteonectin mRNA in pancreatic cancer compared to cancer of the papilla of Vater

Klaus L. Prenzel, Ute Warnecke-Eberz, Huan Xi, Jan Brabender, Stephan E. Baldus, Elfriede Bollschweiler, Christian A. Gutschow, Arnulf H. Hölscher, Paul M. Schneider
Pages: 1397-1401
Published online on: 01 May 2006

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

KDM5D expression is lost in cisplatin‑resistant neuroblastoma cells

Natalia Podhorska, Jan Hrabeta, Marie Belhajova, Tomas Eckschlager
Article Number: 79
Published online on: 25 February 2026

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Article Open Access

Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer

Alban Piotrowsky, Christian Leischner, Hendrik Schmieder, Katja Detert, Kathrin Schneider, Johanna Schulte, Sabrina Hammerschmidt, Luigi Marongiu, Olga Renner, Markus Burkard, Sascha Venturelli
Article Number: 78
Published online on: 24 February 2026

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Review Open Access

Advances in immunotherapy and targeted therapy for nasopharyngeal carcinoma: Current progress and combined approaches (Review)

Zhen Yang, Huajun Liu, Meilin Chen, Liming Zhang, Meiling Gong, Ruilian Yu
Article Number: 77
Published online on: 24 February 2026

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Retraction Open Access

[Retracted] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Article Number: 76
Published online on: 24 February 2026

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Article Open Access

NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells

Tingyu Zhang, Yue Wang, Jiuna Zhang, Xueshuai Ye, Yanfeng Shen, Zhiwei Zhang
Article Number: 75
Published online on: 18 February 2026

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Article

Hypoxia‑induced miR‑135b‑5p promotes neuroendocrine differentiation of prostate cancer cells through HIF1AN‑HIF1α axis

Pampana Sandhya Venkata Lakshmi, Jagrati Parashar, Biswajit Biswas, Ramesh Ummanni
Article Number: 74
Published online on: 16 February 2026

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Retraction Open Access

[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP‑9

Zhu Yuan, Andrew J. Sanders, Lin Ye, Yu Wang, Wen G. Jiang
Article Number: 73
Published online on: 16 February 2026

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Review Open Access

Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 72
Published online on: 12 February 2026

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Article Open Access

Tumor visualization and evaluation of glioblastoma in mice using small animal 9.4T MRI and PET‑CT with high resolution

Shuangyi Li, Wenjiao Gu, Ying Jiang, Ting Liu, Limei Shuai, Yujie Wei, Youming Shi, Havyarimana Juvenal, Zhimin Wang, Yucai Wei, Bofan Wu, Xiaochun Zhou, Yumin Li, Futian Tang
Article Number: 71
Published online on: 12 February 2026

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Expression of Concern Open Access

[Expression of Concern] Interference of STAT 5b expression enhances the chemo‑sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway‑mediated cell apoptosis

Tao Sun, Yanfei Jia, Dongjie Xiao
Article Number: 70
Published online on: 11 February 2026

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Article Open Access

Regorafenib and Nifuroxazide exert enhanced suppression of hepatocellular carcinoma by inhibiting STAT3 and immune remodeling

Kun Li, Jinwei Chen, Zhi Zheng, Yichun Gao, Jiayu Zhang, Wenya Ding, Tongguo Yang, Yuyang Gu, Xuhua Duan, Tiesuo Zhao, Huijie Jia, Pengfei Chen, Jianzhuang Ren
Article Number: 69
Published online on: 11 February 2026

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Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma

Mengnan Guo, He Li, Zhifang Zhao, Yuanyuan Wang, Jiaqi Tang, Binghan Zhong, Yunxia Zhao
Article Number: 68
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] miR‑218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D

Quanxing Cao, Pingshuan Dong, Yanyu Wang, Junwei Zhang, Xinge Shi, Yongsheng Wang
Article Number: 67
Published online on: 09 February 2026

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Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held‑Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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