Carcinoma of the cervical stump: Fifty years of experience

  • Authors:
    • Ann-Cathrin Hellström
    • Kristina Hellman
    • B. Folke Pettersson
    • Sonia Andersson
  • View Affiliations

  • Published online on: March 22, 2011     https://doi.org/10.3892/or.2011.1228
  • Pages: 1651-1654
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

A series of patients with carcinoma of the cervical stump in relation to age, clinical stage, histopathology, changes in relative incidence, treatment outcome and long-term survival, were studied and the findings were compared with matched controls that have an intact uterus and cancer of the cervix. Of 8,028 women treated for invasive cervical carcinoma between 1959-2004, 161 were diagnosed with stump cancer, accounting for 2.0% of all cervical cancers. The mean time interval between subtotal hysterectomy and stump cancer diagnosis was 17.6 years, with a range of 1-46 years. In 80% of cases, symptoms drove the patient to seek medical attention and postcoital, intermenstrual or postmenopausal bleeding was the main reason. Among 161 stump cancer cases 89% were squamous cell carcinoma (SCC) and the remaining 17 cases were adenocarcinomas (AC). Cumulative cause-specific survival rate was significantly worse for adenocarcinoma than for squamous cell carcinoma (SCC) of the cervical stump (Log-rank p=0.027, Cox-Mantel p=0.015, Cox F-test p=0.01). The stump cancer cases show a worse stage profile compared with the cancer cases in intact uterus. We conclude that the total effect of stump cancers following subtotal hysterectomies is not to be neglected.

Related Articles

Journal Cover

June 2011
Volume 25 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Hellström A, Hellman K, Pettersson BF and Andersson S: Carcinoma of the cervical stump: Fifty years of experience . Oncol Rep 25: 1651-1654, 2011
APA
Hellström, A., Hellman, K., Pettersson, B.F., & Andersson, S. (2011). Carcinoma of the cervical stump: Fifty years of experience . Oncology Reports, 25, 1651-1654. https://doi.org/10.3892/or.2011.1228
MLA
Hellström, A., Hellman, K., Pettersson, B. F., Andersson, S."Carcinoma of the cervical stump: Fifty years of experience ". Oncology Reports 25.6 (2011): 1651-1654.
Chicago
Hellström, A., Hellman, K., Pettersson, B. F., Andersson, S."Carcinoma of the cervical stump: Fifty years of experience ". Oncology Reports 25, no. 6 (2011): 1651-1654. https://doi.org/10.3892/or.2011.1228