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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2011 Volume 25 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Induction of arginosuccinate synthetase (ASS) expression affects the antiproliferative activity of arginine deiminase (ADI) in melanoma cells

Antonella Manca, Maria Cristina Sini, Francesco Izzo, Paolo A. Ascierto, Fabiana Tatangelo, Gerardo Botti, Giusy Gentilcore, Marilena Capone, Nicola Mozzillo, Carla Rozzo, Antonio Cossu, Francesco Tanda, Giuseppe Palmieri
Pages: 1495-1502
Published online on: 18 March 2011

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Article

Claudin-11 decreases the invasiveness of bladder cancer cells

Ninaad S. Awsare, Tracey A. Martin, Mark D. Haynes, Philip N. Matthews, Wen G. Jiang
Pages: 1503-1509
Published online on: 04 April 2011

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Article

Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer

Zhongyun Dong, Yin Liu, Linda Levin, Leslie Oleksowicz, Jiang Wang, Shan Lu
Pages: 1511-1516
Published online on: 29 March 2011

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Article

Impact of MET amplification on gastric cancer: Possible roles as a novel prognostic marker and a potential therapeutic target

Jeeyun Lee, Jin Won Seo, Hyun Jung Jun, Chang-Seok Ki, Se Hoon Park, Young Suk Park, Ho Yeong Lim, Min Gew Choi, Jae Moon Bae, Tae Sung Sohn, Jae Hyung Noh, Sung Kim, Hey-Lim Jang, Ji-Youn Kim, Kyoung-Mee Kim, Won Ki Kang, Joon Oh Park
Pages: 1517-1524
Published online on: 18 March 2011

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Article

Optimization of hyperthermia and dendritic cell immunotherapy for squamous cell carcinoma

Koushi Matsumoto, Noriyuki Yamamoto, Sumitaka Hagiwara, Masaki Saito, Hiroki Furue, Toshio Shigetomi, Yuji Narita, Kenji Mitsudo, Iwai Tohnai, Takeshi Kobayashi, Minoru Ueda
Pages: 1525-1532
Published online on: 23 March 2011

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Article

Overexpression of Forkhead box M1 protein associates with aggressive tumor features and poor prognosis of hepatocellular carcinoma

Hong-Cheng Sun, Min Li, Ji-Lin Lu, Dong-Wang Yan, Chong-Zhi Zhou, Jun-Wei Fan, Xue-Bin Qin, Hua-Mei Tang, Zhi-Hai Peng
Pages: 1533-1539
Published online on: 22 March 2011

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Article

Granulocyte colony-stimulating factor expression as a prognostic biomarker in non-small cell lung cancer

G. P. Stathopoulos, A. Armakolas, T. Tranga, H. Marinou, J. Stathopoulos, H. Chandrinou
Pages: 1541-1544
Published online on: 22 March 2011

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Article

Cigarette smoking habit does not reduce the benefit from first line trastuzumab-based treatment in advanced breast cancer patients

Daniele Santini, Bruno Vincenzi, Vincenzo Adamo, Raffaele Addeo, Vittorio Fusco, Antonio Russo, Filippo Montemurro, Ilaria Roato, Stefania Redana, Gaetano Lanzetta, Maria Antonietta Satolli, Alfredo Berruti, Valentina Leoni, Sara Galluzzo, Mauro Antimi, Giuseppa Ferraro, Maura Rossi, Salvatore Del Prete, Maria Rosaria Valerio, Monica Marra, Michele Caraglia, Giuseppe Tonini
Pages: 1545-1548
Published online on: 28 March 2011

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Article

Immunogenic apoptosis in human acute myeloid leukemia (AML): primary human AML cells expose calreticulin and release heat shock protein (HSP) 70 and HSP90 during apoptosis

Hanne Fredly, Elisabeth Ersvær, Bjørn-Tore Gjertsen, Øystein Bruserud
Pages: 1549-1556
Published online on: 22 March 2011

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Article

Antitumor activity of monomethoxy poly(ethylene glycol)-poly (ε-caprolactone) micelle-encapsulated doxorubicin against mouse melanoma

Lan Zheng, Maling Gou, Shengtao Zhou, Tao Yi, Qian Zhong, Zhengyu Li, Xiang He, Xiancheng Chen, Lina Zhou, Yuquan Wei, Zhiyong Qian, Xia Zhao
Pages: 1557-1564
Published online on: 31 March 2011

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Article

The insulin-like growth factor-I receptor kinase inhibitor NVP-ADW742 sensitizes medulloblastoma to the effects of chemotherapy

Hui Zhou, Jing Rao, Jian Lin, Bo Yin, Hansong Sheng, Fengchun Lin, Nu Zhang, Lin Yang
Pages: 1565-1571
Published online on: 23 March 2011

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Article

Effect of hyperthermia on invasion ability and TGF-β1 expression of breast carcinoma MCF-7 cells

Xiaoxue Xie, Xunfan Shao, Fuping Gao, Hekun Jin, Jumei Zhou, Lehui Du, Yingying Zhang, Weiwei Ouyang, Xiaowen Wang, Lingyun Zhao, Xiaodong Zhang, Jintian Tang
Pages: 1573-1579
Published online on: 29 March 2011

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Article

TGF-β1 mediates epithelial to mesenchymal transition via the TGF-β/Smad pathway in squamous cell carcinoma of the head and neck Expression of Concern in /10.3892/or.2025.9001

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Pages: 1581-1587
Published online on: 07 April 2011

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Article

Lymphovascular invasion is an important predictor of lymph node metastasis in endoscopically resected early gastric cancers

Hyunki Kim, Jie-Hyun Kim, Jun Chul Park, Yong Chan Lee, Sung Hoon Noh, Hoguen Kim
Pages: 1589-1595
Published online on: 30 March 2011

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Article

4-Hexylresorcinol inhibits transglutaminase-2 activity and has synergistic effects along with cisplatin in KB cells

Seong-Gon Kim, Jae-Hwan Jeong, Young-Wook Park, Ji-Young Song, An-Sook Kim, Je-Yong Choi, Weon-Sik Chae
Pages: 1597-1602
Published online on: 17 March 2011

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Article

DNA copy number aberrations associated with the clinicopathological features of colorectal cancers: Identification of genomic biomarkers by array-based comparative genomic hybridization

Motonao Nakao, Shigeto Kawauchi, Tetsuji Uchiyama, Jun Adachi, Hideaki Ito, Yasuyo Chochi, Tomoko Furuya, Atsunori Oga, Kohsuke Sasaki
Pages: 1603-1611
Published online on: 05 April 2011

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Article

Survivin overexpression correlates with an apoptosis-resistant phenotype in chronic myeloid leukemia cells

Gabriela Nestal de Moraes, Karina Lani Silva, Flavia da Cunha Vasconcelos, Raquel Ciuvalschi Maia
Pages: 1613-1619
Published online on: 22 March 2011

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Article

PEG-liposomal oxaliplatin potentialization of antitumor efficiency in a nude mouse tumor-xenograft model of colorectal carcinoma

Chuang Yang, Hai-Zhong Liu, Wei-Dong Lu, Zhong-Xue Fu
Pages: 1621-1628
Published online on: 29 March 2011

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Article

LRIG1 combined with cisplatin enhances bladder cancer lesions via a novel pathway

Fan Li, Weimin Yang, Dongsheng Guo, Zhiquan Hu, Hua Xu, Zhangqun Ye
Pages: 1629-1637
Published online on: 22 March 2011

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Article

Factors influencing the detection of the BRAF T1799A mutation in papillary thyroid carcinoma

Hye Soo Kim, Jong Ok Kim, Dong Ho Lee, Han Chul Lee, Hee Jin Kim, Jeong Hwan Kim, Yi Sun Jang, Jong Min Lee, Seon Young Kim, Yong Sung Kim
Pages: 1639-1644
Published online on: 22 March 2011

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Article

Aquaporin 5 expression increases mucin production in lung adenocarcinoma

Zi-Qiang Zhang, Zhu-Xian Zhu, Chun-Xue Bai, Zhi-Hong Chen
Pages: 1645-1650
Published online on: 30 March 2011

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Article

Carcinoma of the cervical stump: Fifty years of experience

Ann-Cathrin Hellström, Kristina Hellman, B. Folke Pettersson, Sonia Andersson
Pages: 1651-1654
Published online on: 22 March 2011

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Article

Acute application of cisplatin affects methylation status in neuroblastoma cells

Keiichi Tabata, Hayato Sakai, Ryosuke Nakajima, Reiko Saya-Nishimura, Kou Motani, Soichiro Okano, Yasuko Shibata, Yoshimitsu Abiko, Takashi Suzuki
Pages: 1655-1660
Published online on: 18 March 2011

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Article Open Access

Restoration of miR-517a expression induces cell apoptosis in bladder cancer cell lines

Takayuki Yoshitomi, Kazumori Kawakami, Hideki Enokida, Takeshi Chiyomaru, Ichiro Kagara, Shuichi Tatarano, Hirofumi Yoshino, Hiroshi Arimura, Kenryu Nishiyama, Naohiko Seki, Masayuki Nakagawa
Pages: 1661-1668
Published online on: 08 April 2011

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Article

Comparison of three distinct methods for the detection of circulating tumor cells in colorectal cancer patients

Annalisa Gervasoni, Maria Teresa Sandri, Riccardo Nascimbeni, Laura Zorzino, Maria Cristina Cassatella, Luigi Baglioni, Sara Panigara, Maria Gervasi, Diego Di Lorenzo, Ornella Parolini
Pages: 1669-1703
Published online on: 23 March 2011

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Article

Histone deacetylases 1, 6 and 8 are critical for invasion in breast cancer

Soon Young Park, Ji Ae Jun, Kang Jin Jeong, Hoi Jeong Heo, Jang Sihn Sohn, Hoi Young Lee, Chang Gyo Park, Jaeku Kang
Pages: 1677-1681
Published online on: 28 March 2011

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Article Open Access

Genetically modified tumour vaccines producing IL-12 augment chemotherapy of HPV16-associated tumours with gemcitabine

Romana Mikyšková, Marie Indrová, Jana Šímová, Jana Bieblová, Jan Bubeník, Milan Reiniš
Pages: 1683-1689
Published online on: 18 March 2011

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Article

KRAS, BRAF and PIK3CA mutations in human colorectal cancer: Relationship with metastatic colorectal cancer

Hong-Tao Li, Yuan-Yuan Lu, Yan-Xin An, Xin Wang, Qing-Chuan Zhao
Pages: 1691-1697
Published online on: 17 March 2011

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Article

The DPP-IV inhibitor ER-319711 has a proliferative effect on the colonic epithelium and a minimal effect in the amelioration of colitis

Hiromitsu Ban, Shigeki Bamba, Hirotsugu Imaeda, Osamu Inatomi, Ayako Kobori, Masaya Sasaki, Tomoyuki Tsujikawa, Akira Andoh, Yoshihide Fujiyama
Pages: 1699-1703
Published online on: 22 March 2011

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Article

Proteasome inhibition by MG132 induces growth inhibition and death of human pulmonary fibroblast cells in a caspase-independent manner

Bo Ra You, Woo Hyun Park
Pages: 1705-1712
Published online on: 08 March 2011

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Article

Resveratrol induces apoptosis in breast cancer cells by E2F1-mediated up-regulation of ASPP1

Yujie Shi, Shihe Yang, Sandi Troup, Xin Lu, Steve Callaghan, David S. Park, Ying Xing, Xiaohe Yang
Pages: 1713-1719
Published online on: 06 April 2011

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Article

microRNA-21 modulates cell proliferation and sensitivity to doxorubicin in bladder cancer cells

Jun Tao, Qiang Lu, Deyao Wu, Pengchao Li, Bin Xu, Weijie Qing, Meilin Wang, Zhengdong Zhang, Wei Zhang
Pages: 1721-1729
Published online on: 04 April 2011

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Article

Prevalence and association of human papillomavirus 16, Epstein-Barr virus, herpes simplex virus-1 and cytomegalovirus infection with human esophageal carcinoma: A case-control study

Dong-Hong Zhang, Qing-Ying Zhang, Chao-Qun Hong, Jiong-Yu Chen, Zhong-Ying Shen, Yi Zhu
Pages: 1731-1738
Published online on: 23 March 2011

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Article

Ursodeoxycholic acid-induced inhibition of DLC1 protein degradation leads to suppression of hepatocellular carcinoma cell growth

Goh Eun Chung, Jung-Hwan Yoon, Jeong-Hoon Lee, Hwi Young Kim, Sun Jung Myung, Su Jong Yu, Sung-Hee Lee, Soo-Mi Lee, Yoon Jun Kim, Hyo-Suk Lee
Pages: 1739-1746
Published online on: 29 March 2011

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Article

microRNA-145 suppresses lung adenocarcinoma-initiating cell proliferation by targeting OCT4

Rong Yin, Shuai Zhang, Yaqin Wu, Xiaohu Fan, Feng Jiang, Zhi Zhang, Dongjie Feng, Xirong Guo, Lin Xu
Pages: 1747-1754
Published online on: 07 April 2011

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Article

Involvement of p53 R72P polymorphism in the association of MDM2-SNP309 with breast cancer

Jyh-Der Leu, Chung-Yih Wang, Han-Yi Tsai, I-Feng Lin, Ran-Chou Chen, Yi-Jang Lee
Pages: 1755-1763
Published online on: 08 April 2011

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Article

The NQO1*2/*2 polymorphism is associated with poor overall survival in patients following resection of stages II and IIIa non-small cell lung cancer

Jill M. Kolesar, Suzanne E. Dahlberg, Sharon Marsh, Howard L. McLeod, David H. Johnson, Steven M. Keller, Joan H. Schiller
Pages: 1765-1772
Published online on: 06 April 2011

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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