|
1
|
Carlson A, Berkowitz JM, Browning D,
Slamon DJ, Gasson JC and Yates KE: Expression of c-Fes protein
isoforms correlates with differentiation in myeloid leukemias. DNA
Cell Biol. 24:311–316. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Gaillard JB, Arnould C, Bravo S, et al:
Exon 7 deletion in the bcr-abl gene is frequent in chronic myeloid
leukemia patients and is not correlated with resistance against
imatinib. Mol Cancer Ther. 9:3083–3089. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Matulic M, Paradzik M, Puskaric BJ, Stipic
J and Antica M: Analysis of Ikaros family splicing variants in
human hematopoietic lineages. Coll Antropol. 34:59–62.
2010.PubMed/NCBI
|
|
4
|
Vassen L, Khandanpour C, Ebeling P, et al:
Growth factor independent 1b (Gfi1b) and a new splice variant of
Gfi1b are highly expressed in patients with acute and chronic
leukemia. Int J Hematol. 89:422–430. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Wihlidal P, Varga F, Pfeilstocker M and
Karlic H: Expression and functional significance of osteocalcin
splicing in disease progression of hematological malignancies. Leuk
Res. 30:1241–1248. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Rogers SL, Zhao Y, Jiang X, Eaves CJ,
Mager DL and Rouhix A: Expression of the leukemic prognostic marker
CD7 is linked to epigenetic modifications in chronic myeloid
leukemia. Mol Cancer. 9:412010. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Luco RF, Allo M, Schor IE, Kornblihtt AR
and Misteli T: Epigenetics in alternative pre-mRNA splicing. Cell.
144:16–26. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Luco RF, Pan Q, Tominaga K, Blencowe BJ,
Pereira-Smith OM and Misteli T: Regulation of alternative splicing
by histone modifications. Science. 327:996–1000. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Milutinovic S, D’Alessio AC, Detich N and
Szyf M: Valproate induces widespread epigenetic reprogramming which
involves demethylation of specific genes. Carcinogenesis.
28:560–571. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Brichta L, Hofmann Y, Hahnen E, et al:
Valproic acid increases the SMN2 protein level: a well-known drug
as a potential therapy for spinal muscular atrophy. Hum Mol Genet.
12:2481–2489. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Langer W, Sohler F, Leder G, et al: Exon
array analysis using re-defined probe sets results in reliable
identification of alternatively spliced genes in non-small cell
lung cancer. BMC Genomics. 11:6762010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Moller-Levet CS, Betts GN, Harris AL,
Homer JJ, West CM and Miller CJ: Exon array analysis of head and
neck cancers identifies a hypoxia related splice variant of LAMA3
associated with a poor prognosis. PLoS Comput Biol. 5:e10005712009.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Chen H, Guo Y, Hu M, Duan W, Chang G and
Li C: Differential expression and alternative splicing of genes in
lumbar spinal cord of an amyotrophic lateral sclerosis mouse model.
Brain Res. 1340:52–69. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Johnson MB, Kawasawa YI, Mason CE, et al:
Functional and evolutionary insights into human brain development
through global transcriptome analysis. Neuron. 62:494–509. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Shi YH, Zhu SW, Mao XZ, et al:
Transcriptome profiling, molecular biological, and physiological
studies reveal a major role for ethylene in cotton fiber cell
elongation. Plant Cell. 18:651–664. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Gardina PJ, Clark TA, Shimada B, et al:
Alternative splicing and differential gene expression in colon
cancer detected by a whole genome exon array. BMC Genomics.
7:3252006. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
|
|
18
|
Leparc GG and Mitra RD: A sensitive
procedure to detect alternatively spliced mRNA in pooled-tissue
samples. Nucleic Acids Res. 35:e1462007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Romanski A, Bacic B, Bug G, et al: Use of
a novel histone deacetylase inhibitor to induce apoptosis in cell
lines of acute lymphoblastic leukemia. Haematologica. 89:419–426.
2004.PubMed/NCBI
|
|
20
|
Morotti A, Cilloni D, Messa F, et al:
Valproate enhances imatinib-induced growth arrest and apoptosis in
chronic myeloid leukemia cells. Cancer. 106:1188–1196. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Raffoux E, Cras A, Recher C, et al: Phase
2 clinical trial of 5-azacitidine, valproic acid, and all-trans
retinoic acid in patients with high-risk acute myeloid leukemia or
myelodysplastic syndrome. Oncotarget. 1:34–42. 2010.PubMed/NCBI
|
|
22
|
Fredly H, Stapnes Bjornsen C, Gjertsen BT
and Bruserud O: Combination of the histone deacetylase inhibitor
valproic acid with oral hydroxyurea or 6-mercaptopurin can be safe
and effective in patients with advanced acute myeloid leukaemia: a
report of five cases. Hematology. 15:338–343. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Buchi F, Pastorelli R, Ferrari G, et al:
Acetylome and phosphoproteome modifications in imatinib resistant
chronic myeloid leukaemia cells treated with valproic acid. Leuk
Res. 35:921–923. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kircher B, Schumacher P, Petzer A, et al:
Anti-leukemic activity of valproic acid and imatinib mesylate on
human Ph+ ALL and CML cells in vitro. Eur J Haematol.
83:48–56. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Cheng YC, Lin H, Huang MJ, Chow JM, Lin S
and Liu HE: Downregulation of c-Myc is critical for valproic
acid-induced growth arrest and myeloid differentiation of acute
myeloid leukemia. Leuk Res. 31:1403–1411. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Bokelmann I and Mahlknecht U: Valproic
acid sensitizes chronic lymphocytic leukemia cells to apoptosis and
restores the balance between pro- and antiapoptotic proteins. Mol
Med. 14:20–27. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Stamatopoulos B, Meuleman N, De Bruyn C,
et al: Antileukemic activity of valproic acid in chronic
lymphocytic leukemia B cells defined by microarray analysis.
Leukemia. 23:2281–2289. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Khanim FL, Bradbury CA, Arrazi J, et al:
Elevated FOSB-expression; a potential marker of valproate
sensitivity in AML. Br J Haematol. 144:332–341. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Skotheim RI and Nees M: Alternative
splicing in cancer: noise, functional, or systematic? Int J Biochem
Cell Biol. 39:1432–1449. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
He C, Zhou F, Zuo Z, Cheng H and Zhou R: A
global view of cancer-specific transcript variants by subtractive
transcriptome-wide analysis. PLoS One. 4:e47322009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Fackenthal JD and Godley LA: Aberrant RNA
splicing and its functional consequences in cancer cells. Dis Model
Mech. 1:37–42. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Schwerk C and Schulze-Osthoff K:
Regulation of apoptosis by alternative pre-mRNA splicing. Mol Cell.
19:1–13. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Wang Q and Silver PA: Genome-wide RNAi
screen discovers functional coupling of alternative splicing and
cell cycle control to apoptosis regulation. Cell Cycle.
9:4419–4421. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Kim E, Goren A and Ast G: Insights into
the connection between cancer and alternative splicing. Trends
Genet. 24:7–10. 2008. View Article : Google Scholar
|
|
35
|
Makishima H, Cazzolli H, Szpurka H, et al:
Mutations of e3 ubiquitin ligase cbl family members constitute a
novel common pathogenic lesion in myeloid malignancies. J Clin
Oncol. 27:6109–6116. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Keane MM, Ettenberg SA, Nau MM, et al:
cbl-3: a new mammalian cbl family protein. Oncogene. 18:3365–3375.
1999. View Article : Google Scholar : PubMed/NCBI
|
