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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2012 Volume 27 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

miRNAs in breast cancer tumorigenesis (Review)

Zhong Ju Zhang, Shi Liang Ma
Pages: 903-910
Published online on: 23 December 2011

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Article Open Access

MAGE A1-A6 RT-PCR and MAGE A3 and p16 methylation analysis in induced sputum from patients with lung cancer and non-malignant lung diseases

Kyeong-Cheol Shin, Kwan-Ho Lee, Chae-Hun Lee, Im-Hee Shin, Hun-Suk Suh, Chang-Ho Jeon
Pages: 911-916
Published online on: 29 November 2011

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Article Open Access

Downregulation of S100A4 expression by RNA interference suppresses cell growth and invasion in human colorectal cancer cells

Liyong Huang, Ye Xu, Guoxiang Cai, Zuqing Guan, Sanjun Cai
Pages: 917-922
Published online on: 20 December 2011

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Article Open Access

Continuous inhibition of epidermal growth factor receptor phosphorylation by erlotinib enhances antitumor activity of chemotherapy in erlotinib-resistant tumor xenografts

Toshiki Iwai, Yoichiro Moriya, Masatoshi Shirane, Kaori Fujimoto-Ouchi, Kazushige Mori
Pages: 923-928
Published online on: 30 December 2011

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Article Open Access

microRNA-1301-mediated inhibition of tumorigenesis

Lin Fang, Ning Yang, Jie Ma, Yong Fu, Guang-Shun Yang
Pages: 929-934
Published online on: 12 December 2011

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Article Open Access

UVC irradiation suppresses platelet-derived growth factor-BB-induced migration in human pancreatic cancer cells

Junji Kawaguchi, Seiji Adachi, Ichiro Yasuda, Takahiro Yamauchi, Takashi Yoshioka, Masahiko Itani, Osamu Kozawa, Hisataka Moriwaki
Pages: 935-939
Published online on: 23 December 2011

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Article

Assessment of stanniocalcin-1 as a prognostic marker in human esophageal squamous cell carcinoma

Mitsuhiro Shirakawa, Yoshiyuki Fujiwara, Yurika Sugita, Jeong-Ho Moon, Shuji Takiguchi, Kiyokazu Nakajima, Hiroshi Miyata, Makoto Yamasaki, Masaki Mori, Yuichiro Doki
Pages: 940-946
Published online on: 22 December 2011

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Article

Prognostic significance of CTCs and CSCs of tumor drainage vein blood in Dukes' stage B and C colorectal cancer patients

Ryu Shimada, Hisae Iinuma, Takuya Akahane, Atsushi Horiuchi, Toshiaki Watanabe
Pages: 947-953
Published online on: 19 January 2012

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Article

Heparin-binding epidermal growth factor-like growth factor is a potent regulator of invasion activity in oral squamous cell carcinoma

Yuichi Ohnishi, Hiroshi Inoue, Masayuki Furukawa, Kenji Kakudo, Masami Nozaki
Pages: 954-958
Published online on: 30 December 2011

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Article

Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells

Bin-Chuan Ji, Chien-Chih Yu, Su-Tso Yang, Te-Chun Hsia, Jai-Sing Yang, Kuang-Chi Lai, Yang-Ching Ko, Jen-Jyh Lin, Tung-Yuan Lai, Jing-Gung Chung
Pages: 959-964
Published online on: 04 January 2012

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Article

Role of the ABCE1 gene in human lung adenocarcinoma

Yi Ren, Yinghui Li, Dali Tian
Pages: 965-970
Published online on: 19 January 2012

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Article

Downregulation of Mcl-1 synergizes the apoptotic response to combined treatment with cisplatin and a novel fiber chimeric oncolytic adenovirus

Liangshun You, Ying Wang, Yingming Jin, Wenbin Qian
Pages: 971-978
Published online on: 16 January 2012

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Article

The role of expression and polymorphism of the BAG-1 gene in response to platinum-based chemotherapeutics in NSCLC

Ya-Di Wang, Min-Wen Ha, Jian Cheng, Wen-Lu Zhang, Xue Cong, Chun-Yan Tong, Jing Sun
Pages: 979-986
Published online on: 13 December 2011

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Article

Identification of ERp29 as a biomarker for predicting nasopharyngeal carcinoma response to radiotherapy

Ping Wu, Hua Zhang, Lin Qi, Qingping Tang, Yaoyun Tang, Zhihai Xie, Yunxia Lv, Suping Zhao, Weihong Jiang
Pages: 987-994
Published online on: 08 December 2011

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Article

The distribution and retention of paclitaxel and doxorubicin in multicellular layer cultures

Joo-Ho Lee, Kun Na, Soo-Chang Song, Jaehwi Lee, Hyo-Jeong Kuh
Pages: 995-1002
Published online on: 20 January 2012

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Article

The effects of cyclooxygenase-2 gene silencing by siRNA on cell proliferation, cell apoptosis, cell cycle and tumorigenicity of Capan-2 human pancreatic cancer cells

Yingqiang Zhong, Zhongsheng Xia, Juan Liu, Ying Lin, Hui Zan
Pages: 1003-1010
Published online on: 19 December 2011

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Article

Loss of breast cancer metastasis suppressor 1 promotes ovarian cancer cell metastasis by increasing chemokine receptor 4 expression

Xiu-Jie Sheng, Ying-Qun Zhou, Qing-Yuan Song, Dong-Mei Zhou, Qi-Cai Liu
Pages: 1011-1018
Published online on: 19 December 2011

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Article

microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN

Bao Gui Zhang, Jian Fang Li, Bei Qin Yu, Zheng Gang Zhu, Bing Ya Liu, Min Yan
Pages: 1019-1026
Published online on: 19 January 2012

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Article

Short hairpin RNA targeting Twist1 suppresses cell proliferation and improves chemosensitivity to cisplatin in HeLa human cervical cancer cells

Kexiu Zhu, Lihong Chen, Xiaobing Han, Jia Wang, Jue Wang
Pages: 1027-1034
Published online on: 12 January 2012

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Article

Camptothecin nanocolloids based on N,N,N-trimethyl chitosan: Efficient suppression of growth of multiple myeloma in a murine model

Zhengguang Li, Xingyi Li, Zhixing Cao, Youzhi Xu, Hongjun Lin, Yinglan Zhao, Yuquan Wei, Zhiyong Qian
Pages: 1035-1040
Published online on: 12 January 2012

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Article

Carnosic acid inhibits the proliferation and migration capacity of human colorectal cancer cells

M. V. Barni, M. J. Carlini, E. G. Cafferata, L. Puricelli, S. Moreno
Pages: 1041-1048
Published online on: 11 January 2012

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Article

Expression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer

Jean-Luc Brun, Annie Cortez, Bénédicte Lesieur, Serge Uzan, Roman Rouzier, Emile Daraï
Pages: 1049-1057
Published online on: 22 December 2011

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Article

Upregulation of β2-microglobulin expression in progressive human oral squamous cell carcinoma

Qian Jiang, Sdek Patima, Dong-Xia Ye, Hong-Ya Pan, Pin Zhang, Zhi-Yuan Zhang
Pages: 1058-1064
Published online on: 30 December 2011

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Article

Expression and correlation of Lewis y antigen and TGF-β1 in ovarian epithelial carcinoma

Sheng-Tan Wang, Juan-Juan Liu, Chang-Zhi Wang, Bei Lin, Ying-Ying Hao, Yi-Fei Wang, Song Gao, Yue Qi, Shu-Lan Zhang, Masao Iwamori
Pages: 1065-1071
Published online on: 01 December 2011

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Article

Expression of caveolin-1 is correlated with disease stage and survival in lung adenocarcinomas

Ping Zhan, Xiao-Kun Shen, Qian Qian, Qin Wang, Ji-Ping Zhu, Yu Zhang, Hai-Yan Xie, Chuen-Hua Xu, Ke-Ke Hao, Wei Hu, Ning Xia, Guo-Jun Lu, Li-Ke Yu
Pages: 1072-1078
Published online on: 21 December 2011

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Article

Recombinant Lz-8 from Ganoderma lucidum induces endoplasmic reticulum stress-mediated autophagic cell death in SGC-7901 human gastric cancer cells

Chongyang Liang, Hongrui Li, Hui Zhou, Shuqin Zhang, Zhiyi Liu, Qiuli Zhou, Fei Sun
Pages: 1079-1089
Published online on: 14 December 2011

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Article

Alpinetin suppresses proliferation of human hepatoma cells by the activation of MKK7 and elevates sensitization to cis-diammined dichloridoplatium Retraction in /10.3892/or.2023.8534

Bo Tang, Jian Du, Jingwen Wang, Guang Tan, Zhenming Gao, Zhongyu Wang, Liming Wang
Pages: 1090-1096
Published online on: 06 December 2011

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Article

miR-24 functions as a tumor suppressor in Hep2 laryngeal carcinoma cells partly through down-regulation of the S100A8 protein

Yan Guo, Weineng Fu, Hong Chen, Chao Shang, Ming Zhong
Pages: 1097-1103
Published online on: 30 November 2011

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Article

A bone-seeking clone exhibits different biological properties from the ACHN parental human renal cell carcinoma in vivo and in vitro

Jiang Wang, Anmin Chen, Caihong Yang, Heng Zeng, Jun Qi, Feng-Jin Guo
Pages: 1104-1110
Published online on: 30 November 2011

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Article

Sodium butyrate-induced DAPK-mediated apoptosis in human gastric cancer cells

Hyunsoo Shin, Yeo Song Lee, Yong Chan Lee
Pages: 1111-1115
Published online on: 08 December 2011

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Article

Bmi-1 induces radioresistance in MCF-7 mammary carcinoma cells

Zhi-Gang Liu, Li Liu, Li-Hua Xu, Wei Yi, Ya-Lan Tao, Zi-Wei Tu, Man-Zhi Li, Mu-Sheng Zeng, Yun-Fei Xia
Pages: 1116-1122
Published online on: 30 December 2011

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Article

EMMPRIN contributes to the in vitro invasion of human salivary adenoid cystic carcinoma cells

Xinjie Yang, Pu Zhang, Qin Ma, Liang Kong, Yuan Li, Baolin Liu, Delin Lei
Pages: 1123-1127
Published online on: 22 December 2011

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Article

Autophagy induced by baicalin involves downregulation of CD147 in SMMC-7721 cells in vitro

Xianjiao Zhang, Xu Tang, Hanqiang Liu, Lianxiang Li, Qian Hou, Jianmin Gao
Pages: 1128-1134
Published online on: 20 December 2011

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Article

Promoter methylation of MGMT, MLH1 and RASSF1A tumor suppressor genes in head and neck squamous cell carcinoma: pharmacological genome demethylation reduces proliferation of head and neck squamous carcinoma cells

Dimitrios Koutsimpelas, Warut Pongsapich, Ulf Heinrich, Sylvia Mann, Wolf J. Mann, Jürgen Brieger
Pages: 1135-1141
Published online on: 09 January 2012

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Article

AAV-mediated gene transfer of human pigment epithelium-derived factor inhibits lewis lung carcinoma growth in mice

Sha-Sha He, Hua-Shan Shi, Tao Yin, Yong-Xia Li, Shun-Tao Luo, Qin-Jie Wu, Lian Lu, Yu-Quan Wei, Li Yang
Pages: 1142-1148
Published online on: 04 January 2012

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Article

Clinical significance of miR-155 expression in breast cancer and effects of miR-155 ASO on cell viability and apoptosis

Shu-Rong Zheng, Gui-Long Guo, Wei Zhang, Guan-Li Huang, Xiao-Qu Hu, Jin Zhu, Qi-Di Huang, Jie You, Xiao-Hua Zhang
Pages: 1149-1155
Published online on: 12 January 2012

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Article

Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer

Yu Wang, Yunxia Wang, Liang Shen, Yingxin Pang, Zhen Qiao, Peishu Liu
Pages: 1156-1162
Published online on: 16 January 2012

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Article

Effective antitumor immunity against murine gliomas using dendritic cells transduced with hTERTC27 recombinant adenovirus

Han-Xian Gong, Lei He, Xiang-Pen Li, Yi-Dong Wang, Yi Li, Jun-Jian Huang, Ziling Wang, Dan Xie, Hsiang-Fu Kung, Ying Peng
Pages: 1163-1169
Published online on: 30 December 2011

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Article

Hepatitis B virus X protein promotes the growth of hepatocellular carcinoma by modulation of the Notch signaling pathway

Fan Wang, Haiyan Zhou, Yuzhen Yang, Xiumei Xia, Qian Sun, Jin Luo, Bin Cheng
Pages: 1170-1176
Published online on: 03 January 2012

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Article

Identification of ABCG2+ cells in nasopharyngeal carcinoma cells

Hongbo Zhang, Weidong Liu, Xiangling Feng, Lei Wang, Xingjun Jiang, Dingyang Liu, Lihua Zhang, Bin Zhu, Wen Zhou, Wenting Jia, Guifei Li, Caiping Ren
Pages: 1177-1187
Published online on: 30 December 2011

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Article

Genetic polymorphisms and cervical cancer development: ATM G5557A and p53bp1 C1236G

S. Oliveira, J. Ribeiro, H. Sousa, D. Pinto, I. Baldaque, R. Medeiros
Pages: 1188-1192
Published online on: 22 December 2011

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Article

p53 codon 72 polymorphism as a progression index for bladder cancer

Hung-Yu Lin, Chun-Hsiung Huang, Tsan-Jung Yu, Wen-Jen Wu, Ming-Chang Yang, For-Wey Lung
Pages: 1193-1199
Published online on: 22 December 2011

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Article

MicroRNA-205 functions as a tumor suppressor in human glioblastoma cells by targeting VEGF-A

Xiao Yue, Peiguo Wang, Jun Xu, Yufang Zhu, Guan Sun, Qi Pang, Rongjie Tao
Pages: 1200-1206
Published online on: 12 December 2011

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Article

A novel TFF2 splice variant (∆EX2TFF2) correlates with longer overall survival time in cholangiocarcinoma

Surasee Kamlua, Siriporn Patrakitkomjorn, Patcharee Jearanaikoon, Trevelyan R. Menheniott, Andrew S. Giraud, Temduang Limpaiboon
Pages: 1207-1212
Published online on: 07 December 2011

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Article

TRAIL is involved in CpG ODN-mediated anti-apoptotic signals

Eun-Jung Lim, Dae-Weon Park, Tae-Whal Jeong, Byung-Rho Chin, Yoe-Sik Bae, Suk-Hwan Baek
Pages: 1213-1218
Published online on: 06 December 2011

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Article

Valproic acid overcomes hypoxia-induced resistance to apoptosis

Šimon Cipro, Jana Hřebačková, Jan Hraběta, Jitka Poljaková, Tomáš Eckschlager
Pages: 1219-1226
Published online on: 06 December 2011

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Article

Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma

Ye Tian, Shizhao Wang, Bin Wang, Jianning Zhang, Rongcai Jiang, Wei Zhang
Pages: 1227-1232
Published online on: 14 December 2011

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Article

Generation of reactive oxygen species mediates butein-induced apoptosis in neuroblastoma cells

Ya-Hui Chen, Chi-Wei Yeh, Hui-Chen Lo, Shih-Li Su, You-Cheng Hseu, Li-Sung Hsu
Pages: 1233-1237
Published online on: 12 January 2012

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Article

Prognostic implications of microRNA-100 and its functional roles in human epithelial ovarian cancer

Dong-Xian Peng, Min Luo, Li-Wen Qiu, Yuan-Li He, Xue-Feng Wang
Pages: 1238-1244
Published online on: 11 January 2012

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Article

Synergistic cytotoxic effect of sulindac and pyrrolidine dithiocarbamate against ovarian cancer cells

Anna Jakubowska-Mućka, Jacek Sieńko, Łukasz Zapała, Rafał Wolny, Witold Lasek
Pages: 1245-1250
Published online on: 16 January 2012

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Article

53BP1 suppresses tumor growth and promotes susceptibility to apoptosis of ovarian cancer cells through modulation of the Akt pathway

Shuhui Hong, Xiaoyan Li, Ying Zhao, Qifeng Yang, Beihua Kong
Pages: 1251-1257
Published online on: 18 January 2012

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Article

Using an exon microarray to identify a global profile of gene expression and alternative splicing in K562 cells exposed to sodium valproate

Xiang-Zhong Zhang, Ai-Hua Yin, Xiao-Yu Zhu, Qian Ding, Chun-Huai Wang, Yun-Xian Chen
Pages: 1258-1265
Published online on: 21 December 2011

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Article

CDK10 functions as a tumor suppressor gene and regulates survivability of biliary tract cancer cells

Jian-Hua Yu, Xiang-Yu Zhong, Wei-Guang Zhang, Zhi-Dong Wang, Qin Dong, Sheng Tai, Hui Li, Yun-Fu Cui
Pages: 1266-1276
Published online on: 30 December 2011

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Article

Increased trefoil factor 3 levels in the serum of patients with three major histological subtypes of lung cancer

Yiqing Qu, Yie Yang, Dedong Ma, Wei Xiao
Pages: 1277-1283
Published online on: 11 January 2012

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Article

MG132, a proteasome inhibitor, induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion

Woo Hyun Park, Suhn Hee Kim
Pages: 1284-1291
Published online on: 19 January 2012

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Article

Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells

Tetsuji Tanaka, Tao Bai, Saori Toujima, Tomoko Utsunomiya, Toshihide Matsuoka, Aya Kobayashi, Madoka Yamamoto, Noriyuki Sasaki, Yuko Tanizaki, Hirotoshi Utsunomiya, Junko Tanaka, Kazunori Yukawa
Pages: 1292-1298
Published online on: 11 January 2012

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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