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Review

miRNAs in breast cancer tumorigenesis (Review)

  • Authors:
    • Zhong Ju Zhang
    • Shi Liang Ma
  • View Affiliations / Copyright

    Affiliations: College of Biological Science and Biotechnology, Shenyang Agricultural University, Shenyang 110866, P.R. China, College of Biological Science and Biotechnology, Shenyang Agricultural University, 120 Dongling Road, Shenyang 110866, P.R. China
  • Pages: 903-910
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    Published online on: December 23, 2011
       https://doi.org/10.3892/or.2011.1611
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Abstract

miRNAs are small, endogenous, non-coding RNAs that negatively regulate protein-coding mRNAs at the post-transcriptional level. It is estimated that in humans thousands of miRNAs are expressed and more than 700 miRNAs have been described to date. About 50% of annotated human miRNAs are detected in regions of fragile sites, which are associated with cancer. The available evidence has shown that miRNAs widely participate in the development or progression of many types of cancers, including breast cancer. The role of miRNAs in breast cancer has been widely investigated; here, we will focus on what is known about the working mechanism of miRNAs in different stages of breast cancer development.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang ZJ and Ma SL: miRNAs in breast cancer tumorigenesis (Review). Oncol Rep 27: 903-910, 2012.
APA
Zhang, Z.J., & Ma, S.L. (2012). miRNAs in breast cancer tumorigenesis (Review). Oncology Reports, 27, 903-910. https://doi.org/10.3892/or.2011.1611
MLA
Zhang, Z. J., Ma, S. L."miRNAs in breast cancer tumorigenesis (Review)". Oncology Reports 27.4 (2012): 903-910.
Chicago
Zhang, Z. J., Ma, S. L."miRNAs in breast cancer tumorigenesis (Review)". Oncology Reports 27, no. 4 (2012): 903-910. https://doi.org/10.3892/or.2011.1611
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang ZJ and Ma SL: miRNAs in breast cancer tumorigenesis (Review). Oncol Rep 27: 903-910, 2012.
APA
Zhang, Z.J., & Ma, S.L. (2012). miRNAs in breast cancer tumorigenesis (Review). Oncology Reports, 27, 903-910. https://doi.org/10.3892/or.2011.1611
MLA
Zhang, Z. J., Ma, S. L."miRNAs in breast cancer tumorigenesis (Review)". Oncology Reports 27.4 (2012): 903-910.
Chicago
Zhang, Z. J., Ma, S. L."miRNAs in breast cancer tumorigenesis (Review)". Oncology Reports 27, no. 4 (2012): 903-910. https://doi.org/10.3892/or.2011.1611
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