|
1
|
American Cancer Society. NY: Global Cancer
Facts & Figures. 2nd edition. http://www.cancer.org/Research/CancerFactsFigures/GlobalCancerFactsFigures/index.
Accessed 2008
|
|
2
|
Malafosse R, Penna C, Sa Cunha A and
Nordlinger B: Surgical management of hepatic metastases from
colorectal malignancies. Ann Oncol. 12:887–894. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Lu J, Getz G, Miska EA, et al: MicroRNA
expression profiles classify human cancers. Nature. 435:834–838.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Lee YS and Dutta A: MicroRNAs in cancer.
Annu Rev Pathol. 4:199–227. 2009. View Article : Google Scholar
|
|
5
|
Schetter AJ, Leung SY, Sohn JJ, et al:
MicroRNA expression profiles associated with prognosis and
therapeutic outcome in colon adenocarcinoma. JAMA. 299:425–436.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Warburg O: On the origin of cancer cells.
Science. 123:309–314. 1956. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Gatenby RA and Gillies RJ: Why do cancers
have high aerobic glycolysis? Nat Rev Cancer. 4:891–899. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Jones RG and Thompson CB: Tumor
suppressors and cell metabolism: a recipe for cancer growth. Gene
Dev. 23:537–548. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Vander Heiden MG, Cantley LC and Thompson
CB: Understanding the Warburg effect: the metabolic requirements of
cell proliferation. Science. 324:1029–1033. 2009.PubMed/NCBI
|
|
10
|
Mazurek S, Boschek CB, Hugo F and
Eigenbrodt E: Pyruvate kinase type M2 and its role in tumor growth
and spreading. Semin Cancer Biol. 15:300–308. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Noguchi T, Inoue H and Tanaka T: The M1-
and M2-type isozymes of rat pyruvate kinase are produced from the
same gene by alternative RNA splicing. J Biol Chem.
261:13807–13812. 1986.PubMed/NCBI
|
|
12
|
Christofk HR, Vander Heiden MG, Wu N,
Asara JM and Cantley LC: Pyruvate kinase M2 is a
phosphotyrosine-binding protein. Nature. 452:181–186. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Vander Heiden MG, Locasale JW, Swanson KD,
et al: Evidence for an alternative glycolytic pathway in rapidly
proliferating cells. Science. 329:1492–1499. 2010.PubMed/NCBI
|
|
14
|
Christofk HR, Vander Heiden MG, Harris MH,
et al: The M2 splice isoform of pyruvate kinase is important for
cancer metabolism and tumour growth. Nature. 452:230–233. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
David CJ, Chen M, Assanah M, Canoll P and
Manley JL: HnRNP proteins controlled by c-Myc deregulate pyruvate
kinase mRNA splicing in cancer. Nature. 463:364–368. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Wang BD, Kline CL, Pastor DM, et al:
Prostate apoptosis response protein 4 sensitizes human colon cancer
cells to chemotherapeutic 5-FU through mediation of an NF kappaB
and microRNA network. Mol Cancer. 9:982010. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Patnaik SK, Kannisto E, Knudsen S and
Yendamuri S: Evaluation of microRNA expression profiles that may
predict recurrence of localized stage I non-small cell lung cancer
after surgical resection. Cancer Res. 70:36–45. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Silber J, Lim DA, Petritsch C, et al:
miR-124 and miR-137 inhibit proliferation of glioblastoma
multiforme cells and induce differentiation of brain tumor stem
cells. BMC Med. 6:142008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Vanderweele DJ and Rudin CM: Mammalian
target of rapamycin promotes vincristine resistance through
multiple mechanisms independent of maintained glycolytic rate. Mol
Cancer Res. 3:635–644. 2005. View Article : Google Scholar
|
|
20
|
Chen M, Zhang J and Manley JL: Turning on
a fuel switch of cancer: hnRNP proteins regulate alternative
splicing of pyruvate kinase mRNA. Cancer Res. 70:8977–8980. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang J, Guo H, Qian G, et al: MiR-145, a
new regulator of the DNA fragmentation factor-45 (DFF45)-mediated
apoptotic network. Mol Cancer. 9:2112010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Akao Y, Nakagawa Y, Hirata I, et al: Role
of anti-oncomirs miR-143 and -145 in human colorectal tumors.
Cancer Gene Ther. 17:398–408. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Gregersen LH, Jacobsen AB, Frankel LB, Wen
J, Krogh A and Lund AH: MicroRNA-145 targets YES and STAT1 in colon
cancer cells. PLoS One. 5:e88362010. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kaelin WG Jr and Thompson CB: Q&A:
Cancer: clues from cell metabolism. Nature. 465:562–564. 2010.
|
|
25
|
Vander Heiden MG, Plas DR, Rathmell JC,
Fox CJ, Harris MH and Thompson CB: Growth factors can influence
cell growth and survival through effects on glucose metabolism. Mol
Cell Biol. 21:5899–5912. 2001.PubMed/NCBI
|
|
26
|
Ashcroft SJ, Weerasinghe LC, Bassett JM
and Randle PJ: The pentose cycle and insulin release in mouse
pancreatic islets. Biochem J. 126:525–532. 1972.PubMed/NCBI
|
|
27
|
Center MM, Jemal A, Smith RA and Ward E:
Worldwide variations in colorectal cancer. CA Cancer J Clin.
59:366–378. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Makeyev EV, Zhang J, Carrasco MA and
Maniatis T: The MicroRNA miR-124 promotes neuronal differentiation
by triggering brain-specific alternative pre-mRNA splicing. Mol
Cell. 27:435–448. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Smith P, Al Hashimi A, Girard J, Delay C
and Hebert SS: In vivo regulation of amyloid precursor protein
neuronal splicing by microRNAs. J Neurochem. 116:240–247. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Werner JM, Eger K and Jurgen Steinfelder
H: Comparison of the rapid pro-apoptotic effect of
trans-beta-nitrostyrenes with delayed apoptosis induced by the
standard agent 5-fluorouracil in colon cancer cells. Apoptosis.
12:235–246. 2007. View Article : Google Scholar
|
|
31
|
Luo W, Hu H, Chang R, et al: Pyruvate
kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible
factor 1. Cell. 145:732–744. 2011. View Article : Google Scholar : PubMed/NCBI
|
