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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2012 Volume 28 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Dendritic cell-based vaccination in metastatic melanoma patients: Phase II clinical trial

Chie Oshita, Masako Takikawa, Akiko Kume, Haruo Miyata, Tadashi Ashizawa, Akira Iizuka, Yoshio Kiyohara, Shusuke Yoshikawa, Ryuji Tanosaki, Naoya Yamazaki, Akifumi Yamamoto, Kazutoh Takesako, Ken Yamaguchi, Yasuto Akiyama
Pages: 1131-1138
Published online on: 07 August 2012

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Article Open Access

BreastDefend™ prevents breast-to-lung cancer metastases in an orthotopic animal model of triple-negative human breast cancer

Jiahua Jiang, Anita Thyagarajan-Sahu, Jagadish Loganathan, Isaac Eliaz, Colin Terry, George E. Sandusky, Daniel Sliva
Pages: 1139-1145
Published online on: 26 July 2012

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Article Open Access

Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells

Kenta Masuda, Kouji Banno, Megumi Yanokura, Kosuke Tsuji, Yusuke Kobayashi, Iori Kisu, Arisa Ueki, Wataru Yamagami, Hiroyuki Nomura, Eiichiro Tominaga, Nobuyuki Susumu, Daisuke Aoki
Pages: 1146-1152
Published online on: 13 July 2012

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Article Open Access

Silencing of the hTERT gene through RNA interference induces apoptosis via bax/bcl-2 in human glioma cells

Tuo Wang, Yan Xue, Maode Wang, Qiang Sun
Pages: 1153-1158
Published online on: 06 August 2012

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Article Open Access

Role of the angiogenic components, VEGFA, FGF2, OPN and RHOC, in urothelial cell carcinoma of the urinary bladder

Apostolos Zaravinos, Dimitrios Volanis, George I. Lambrou, Dimitris Delakas, Demetrios A. Spandidos
Pages: 1159-1166
Published online on: 03 August 2012

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Article Open Access

Anti-angiogenic and antitumor activities of Huaier aqueous extract

Xiaolong Wang, Ning Zhang, Qiang Huo, Qifeng Yang
Pages: 1167-1175
Published online on: 08 August 2012

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Article

Cannabinoids inhibit peptidoglycan-induced phosphorylation of NF-κB and cell growth in U87MG human malignant glioma cells

Ryosuke Echigo, Naotoshi Sugimoto, Akihiro Yachie, Takako Ohno-Shosaku
Pages: 1176-1180
Published online on: 26 July 2012

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Article

Investigation of proNT/NMN secretion from small cell lung carcinoma cells using a mouse xenograft model

Kanako Wakabayashi-Nakao, Koji Maruyama, Hidee Ishii, Koji Muramatsu, Keiichi Hatakeyama, Keiichi Ohshima, Shun-Ichiro Ogura, Takashi Nakajima, Ken Yamaguchi, Tohru Mochizuki
Pages: 1181-1186
Published online on: 23 July 2012

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Article

KIF5B/RET fusion gene in surgically-treated adenocarcinoma of the lung

Keisuke Yokota, Hidefumi Sasaki, Katsuhiro Okuda, Shigeki Shimizu, Masayuki Shitara, Yu Hikosaka, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii
Pages: 1187-1192
Published online on: 13 July 2012

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Article

Antitumor activities of dFv-LDP-AE: An enediyne-energized fusion protein targeting tumor-associated antigen gelatinases

Gen-Shen Zhong, Min-Na Wu, Xiao-Fang Guo, Sheng-Hua Zhang, Qing-Fang Miao, Yong-Su Zhen
Pages: 1193-1199
Published online on: 13 July 2012

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Article

Expression of the mitotic-arrest deficiency 2 is associated with chemotherapy resistance in ovarian serous adenocarcinoma

Yusuke Nakano, Toshiyuki Sumi, Masatomo Teramae, Masanari Morishita, Takeshi Fukuda, Hiroyuki Terada, Hiroyuki Yoshida, Yoshinari Matsumoto, Tomoyo Yasui, Osamu Ishiko
Pages: 1200-1204
Published online on: 12 July 2012

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Article

Molecular detection of cryptic Y-chromosomal material in patients with Turner syndrome

Elva I. Cortés-Gutiérrez, Rosalba Herrera-Bartolo, Martha I. Dávila-Rodríguez, Gerardo C. Palacios-Saucedo, Javier Vargas-Villarreal, Juana B. Romero-Villarreal
Pages: 1205-1210
Published online on: 16 July 2012

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Article

Breast MALT lymphomas: A clinicopathological and cytogenetic study of 9 cases

Giuseppina Liguori, Monica Cantile, Margherita Cerrone, Elvira La Mantia, Maurizio Di Bonito, Fabrizio Zanconati, Maria Pia Curcio, Gabriella Aquino, Anna La Mura, Rosa Giannatiempo, Annarosaria De Chiara, Angela Lombardi, Gerardo Botti, Antonio D'Antonio, Michele Caraglia, Renato Franco
Pages: 1211-1216
Published online on: 27 July 2012

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Article

The mobilization, recruitment and contribution of bone marrow-derived endothelial progenitor cells to the tumor neovascularization occur at an early stage and throughout the entire process of hepatocellular carcinoma growth

Haitao Zhu, Qianwen Shao, Xitai Sun, Zhengming Deng, Xianwen Yuan, Decai Yu, Xiang Zhou, Yitao Ding
Pages: 1217-1224
Published online on: 31 July 2012

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Article

A somatic TSHR mutation in a patient with lung adenocarcinoma with bronchioloalveolar carcinoma, coronary artery disease and severe chronic obstructive pulmonary disease

James Wan Soo Kim, Sharon Lee, Natalie Lui, Helen Choi, Michael Mulvihill, Li Tai Fang, Hio Chung Kang, Yong-Won Kwon, David Jablons, Il-Jin Kim
Pages: 1225-1230
Published online on: 26 July 2012

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Article

High Wilms' tumor 1 mRNA expression correlates with basal-like and ERBB2 molecular subtypes and poor prognosis of breast cancer

Xiao-Wei Qi, Fan Zhang, Xin-Hua Yang, Lin-Jun Fan, Yi Zhang, Yan Liang, Lin Ren, Ling Zhong, Qing-Qiu Chen, Kong-Yong Zhang, Wei-Dong Zang, Li-Shan Wang, Ying Zhang, Jun Jiang
Pages: 1231-1236
Published online on: 12 July 2012

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Article

Expression of miRNA-146a in nasopharyngeal carcinoma is upregulated by Epstein-Barr virus latent membrane protein 1

Yinghai Zhao, Xiaoyi Chen, Min Jing, Haijun Du, Yi Zeng
Pages: 1237-1242
Published online on: 25 July 2012

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Article

Microwave-induced thermoablation with Amica-probe is a safe and reproducible method to treat solid renal masses: Results from a phase I study

Riccardo Bartoletti, Enrico Meliani, Alchiede Simonato, Paolo Gontero, Giovanna Berta, Paolo Dalla Palma, Elena Leonardi, Tommaso Cai, Giorgio Carmignani
Pages: 1243-1248
Published online on: 06 August 2012

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Article

A predicted miR-27a-mediated network identifies a signature of glioma

Shuxu Yang, Kun Wang, Cong Qian, Zhengfei Song, Peiyu Pu, Anling Zhang, Wei Wang, Huanjiang Niu, Xinwei Li, Xuchen Qi, Yinxin Zhu, Yirong Wang
Pages: 1249-1256
Published online on: 07 August 2012

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Article

Role of trefoil factor 1 in gastric cancer and relationship between trefoil factor 1 and gastrokine 1

Wei Mao, Jie Chen, Tie-Li Peng, Xiao-Fei Yin, Lian-Zhou Chen, Min-Hu Chen
Pages: 1257-1262
Published online on: 27 July 2012

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Article

Overexpression of the structural maintenance of chromosome 4 protein is associated with tumor de-differentiation, advanced stage and vascular invasion of primary liver cancer

Bo Zhou, Tao Yuan, Menggang Liu, Hongming Liu, Jun Xie, Yanbin Shen, Ping Chen
Pages: 1263-1268
Published online on: 24 July 2012

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Article

Suppression of heat shock protein 27 expression promotes 5-fluorouracil sensitivity in colon cancer cells in a xenograft model

Ryohei Hayashi, Yoshiyuki Ishii, Hiroki Ochiai, Atsushi Matsunaga, Takashi Endo, Hirotoshi Hasegawa, Yuko Kitagawa
Pages: 1269-1274
Published online on: 25 July 2012

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Article

Human 5-, 12- and 15-lipoxygenase-1 coexist in kidney but show opposite trends and their balance changes in cancer

Amira Gohara, Noha Eltaki, Dina Sabry, Daniel Murtagh , Jerzy Jankun, Steven H. Selman, Ewa Skrzypczak-Jankun
Pages: 1275-1282
Published online on: 20 July 2012

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Article

Fatty acid-binding protein 5 promotes cell proliferation and invasion in human intrahepatic cholangiocarcinoma

Chi-Young Jeong, Young-Sool Hah, Bok Im Cho, Seon Min Lee, Young-Tae Joo, Eun-Jung Jung, Sang-Ho Jeong, Young-Joon Lee, Sang-Kyung Choi, Woo-Song Ha, Soon-Tae Park, Soon-Chan Hong
Pages: 1283-1292
Published online on: 19 July 2012

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Article

Upregulation of miR-20a and miR-106b is involved in the acquisition of malignancy of pediatric brainstem gliomas

Xuan Wang, Hongwei Zhang, Anling Zhang, Lei Han, Kun Wang, Ran Liu, Shaohua Yang, Peiyu Pu, Changhong Shen, Chunsheng Kang, Chunjiang Yu
Pages: 1293-1300
Published online on: 23 July 2012

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Article

Evaluation of CD44 and CD133 as cancer stem cell markers for colorectal cancer

Chunxia Wang, Jingping Xie, Jiasong Guo, H. Charles Manning, John C. Gore, Ning Guo
Pages: 1301-1308
Published online on: 06 August 2012

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Article

Intensity-modulated stereotactic radiotherapy for the treatment of medically inoperable patients with NSCLC stage I

Stephan Lächelt, Markus Alber, Matthias Söhn, Michael  Bamberg, Volker Steger, Martin Weinmann
Pages: 1309-1314
Published online on: 07 August 2012

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Article

Adenovirus-mediated ING4/IL-24 double tumor suppressor gene co-transfer enhances antitumor activity in human breast cancer cells

Yaodong Zhao, Zhengyi Li, Weihua Sheng, Jingchen Miao, Jicheng Yang
Pages: 1315-1324
Published online on: 24 July 2012

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Article

B ultrasound-guided hyperthermic intraperitoneal perfusion chemotherapy for the treatment of malignant ascites

Shuzhong Cui, Mingchen Ba, Yunqiang Tang, Jifang Liu, Yinbing Wu, Bin Wang, Xiangliang Zhang, Hongsheng Tang, Shizhen Zhong
Pages: 1325-1331
Published online on: 13 July 2012

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Article

AAV2-mediated gene transfer of VEGF-Trap with potent suppression of primary breast tumor growth and spontaneous pulmonary metastases by long-term expression

Lian Lu, Shun-Tao Luo, Hua Shan Shi, Meng Li, Hai Long Zhang, Sha Sha He, Yan Liu, Ying Pan, Li Yang
Pages: 1332-1338
Published online on: 16 July 2012

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Article

Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells

Jianteng Wei, Haizhou Liu, Ming Liu, Ning Wu, Jin Zhao, Lin Xiao, Lijun Han, Edward Chu, Xiukun Lin
Pages: 1339-1345
Published online on: 19 July 2012

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Article

miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect

Yan Sun, Xiaoping Zhao, Yuhong Zhou, Yu Hu
Pages: 1346-1352
Published online on: 08 August 2012

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Article

The molecular mechanism of luteolin-induced apoptosis is potentially related to inhibition of angiogenesis in human pancreatic carcinoma cells

Xueting Cai, Wuguang Lu, Tingmei Ye, Min Lu, Jianhua Wang, Jiege Huo, Shihui Qian, Xiaoning Wang, Peng Cao
Pages: 1353-1361
Published online on: 16 July 2012

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Article

Suppression of tumor invasion and migration in breast cancer cells following delivery of siRNA against Stat3 with the antimicrobial peptide PR39

Wenxia Tian, Bing Li, Xiwen Zhang, Weiqi Dang, Xiaofei Wang, Hao Tang, Lin Wang, Hong Cao, Tingmei Chen
Pages: 1362-1368
Published online on: 13 July 2012

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Article

Involvement of ROS in the inhibitory effect of thermotherapy combined with chemotherapy on A549 human lung adenocarcinoma cell growth through the Akt pathway

Lin Wang, Xinkui Liu, Yongjun Wu, Weidong Wu, Yiming Wu
Pages: 1369-1375
Published online on: 07 August 2012

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Article

Rotenone induces KATP channel opening in PC12 cells in association with the expression of tyrosine hydroxylase

Qunhua Bai, Junlin He, Jingfu Qiu, Yang Wang, Shibo Wang, Yun Xiu, Chao Yu
Pages: 1376-1384
Published online on: 08 August 2012

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Article

Immortalized mouse fetal liver stromal cells support growth and maintenance of human embryonic stem cells

Jiabo Hu, Sanqiang Hu, Quanhui Ma, Xiaohui Wang, Zhongwei Zhou, Wei Zhang, Xiaochun Sun, Wei Zhu, Hui Qian, Wenrong Xu
Pages: 1385-1391
Published online on: 13 July 2012

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Article

Decreased expression of the carboxyl terminus of heat shock cognate 70 interacting protein in human gastric cancer and its clinical significance

Lei Gan, Dong-Bo Liu, Hai-Feng Lu, Guo-Xian Long, Qi Mei, Guang-Yuan Hu, Hong Qiu, Guo-Qing Hu
Pages: 1392-1398
Published online on: 08 August 2012

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Article

Ikaros inhibits proliferation and, through upregulation of Slug, increases metastatic ability of ovarian serous adenocarcinoma cells

Li-Cai He, Feng-Hou Gao, Han-Zhang Xu, Shan Zhao, Chun-Min Ma, June Li, Shu Zhang, Ying-Li Wu
Pages: 1399-1405
Published online on: 02 August 2012

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Article

Enhanced cytotoxic effect of low doses of metformin combined with ionizing radiation on hepatoma cells via ATP deprivation and inhibition of DNA repair

Jifang Liu, Min Hou, Taize Yuan, Gao Yi, Shuxu Zhang, Xunfan Shao, Jinhui Chen, Xiaoting Jia, Zhimin He
Pages: 1406-1412
Published online on: 25 July 2012

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Article

Heterogeneous data fusion for brain tumor classification

Vangelis Metsis, Heng Huang, Ovidiu C. Andronesi, Fillia Makedon, Aria Tzika
Pages: 1413-1416
Published online on: 25 July 2012

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Article

Genetic alterations of WWOX in Wilms' tumor are involved in its carcinogenesis

Elżbieta Płuciennik, Magdalena Nowakowska, Wioletta I. Wujcicka, Anna Sitkiewicz, Bernarda Kazanowska, Elżbieta Zielińska, Andrzej K. Bednarek
Pages: 1417-1422
Published online on: 27 July 2012

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Article

Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro

Michael Saugspier, Christoph Dorn, Barbara Czech, Manfred Gehrig, Jörg Heilmann, Claus Hellerbrand
Pages: 1423-1428
Published online on: 20 July 2012

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Article

Pro-apoptotic role of the MEK/ERK pathway in ursodeoxycholic acid-induced apoptosis in SNU601 gastric cancer cells

Sung-Chul Lim, Hong-Quan Duong, Keshab Raj Parajuli, Song Iy Han
Pages: 1429-1434
Published online on: 19 July 2012

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Article

Induction of apoptosis and reduction of MMP gene expression in the U373 cell line by polyphenolics in Aronia melanocarpa and by curcumin

Noor Azela Abdullah Thani, Benjamin Sallis, Robert Nuttall, Frank R. Schubert, Mansoor Ahsan, Derek Davies, Sukhveer Purewal, Alan Cooper, Harcharan K. Rooprai
Pages: 1435-1442
Published online on: 27 July 2012

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Article

Serum interleukin-15 levels in cancer patients with cachexia

Pedro L. Martínez-Hernández, Ángel Hernanz-Macías, Carmen Gómez-Candela, Cristina Grande-Aragón, Jaime Feliu-Batlle, Javier Castro-Carpeño, Isabel Martínez-Muñoz, Laura Zurita-Rosa, Marta Villarino-Sanz, Concepción Prados-Sánchez, Joaquín Sánchez García-Girón
Pages: 1443-1452
Published online on: 23 July 2012

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Article

Inhibition of hepatocellular carcinoma cell growth by an anti-insulin-like growth factor-I receptor monoclonal antibody

Lu Yue, Ying Wang, Huamao Wang, Huiping Gao, Jun Liang, Aihua Sui, Jinyu Xiang, Fang Zhou, Congcong Xu, Wenwen Zhao, Wanhua Liang, Ruyong Yao
Pages: 1453-1460
Published online on: 08 August 2012

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Article

MRS study of meningeal hemangiopericytoma and edema: A comparison with meningothelial meningioma

Valeria Righi, Vitaliano Tugnoli, Adele Mucci, Antonella Bacci, Sergio Bonora, Luisa Schenetti
Pages: 1461-1467
Published online on: 19 July 2012

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Article

SGEF is overexpressed in prostate cancer and contributes to prostate cancer progression

Hongtao Wang, Ruiqin Wu, Lan Yu, Feima Wu, Shanhu Li, Yali Zhao, Hailiang Li, Guolan Luo, Jian Wang, Jianguang Zhou
Pages: 1468-1474
Published online on: 19 July 2012

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Article

Enforced expression of RASAL1 suppresses cell proliferation and the transformation ability of gastric cancer cells

Fengchang Qiao, Xianwei Su, Xuemei Qiu, Danwen Qian, Xiao Peng, Hong Chen, Zhujiang Zhao, Hong Fan
Pages: 1475-1481
Published online on: 19 July 2012

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Article

The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells

Yung-Yi Cheng, Jai-Sing Yang, Shih-Chang Tsai, Chih-Chuang Liaw, Jing-Gung Chung, Li-Jiau Huang, Kuo-Hsiung Lee, Chi-Cheng Lu, Hsi-Cheng Chien, Minoru Tsuzuki, Sheng-Chu Kuo
Pages: 1482-1490
Published online on: 19 July 2012

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Article

The influence of matriptase-2 on prostate cancer in vitro: A possible role for β-catenin

Siobhan L. Webb, Andrew J. Sanders, Malcolm D. Mason, Wen G. Jiang
Pages: 1491-1497
Published online on: 02 August 2012

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Article

MAGEA4 induces growth in normal oral keratinocytes by inhibiting growth arrest and apoptosis

Sheetal Bhan, Alice Chuang, Sandeep S. Negi, Chad A. Glazer, Joseph A. Califano
Pages: 1498-1502
Published online on: 25 July 2012

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Article

Prognostic impact of δ-like ligand 4 and Notch1 in acute myeloid leukemia

Jingru Zhang, Daoxin Ma, Jingjing Ye, Shaolei Zang, Fei Lu, Meixiang Yang, Xun Qu, Xiulian Sun, Chunyan Ji
Pages: 1503-1511
Published online on: 31 July 2012

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Article

Anti-neoplastic effects of fucoxanthin and its deacetylated product, fucoxanthinol, on Burkitt's and Hodgkin's lymphoma cells

Senji Tafuku, Chie Ishikawa, Takeshi Yasumoto, Naoki Mori
Pages: 1512-1518
Published online on: 03 August 2012

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The ubiquitin-conjugating enzyme E2-EPF is overexpressed in cervical cancer and associates with tumor growth

Jing Liang, Hirotaka Nishi, Mei-Lu Bian, Chinatsu Higuma, Toru Sasaki, Hiroe Ito, Keiichi Isaka
Pages: 1519-1525
Published online on: 06 August 2012

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February-2026 Volume 55 Issue 2

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

Yue Chen, Jun Wu, Danxia Zhu, Lu Jiang, Jian Wang, Dachuan Zhang, Wenting He
Article Number: 37
Published online on: 02 January 2026

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Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 55 Issue 3

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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