Journal Articles

Open Access

Dendritic cell-based vaccination in metastatic melanoma patients: Phase II clinical trial

Chie Oshita, Masako Takikawa, Akiko Kume, Haruo Miyata, Tadashi Ashizawa, Akira Iizuka, Yoshio Kiyohara, Shusuke Yoshikawa, Ryuji Tanosaki, Naoya Yamazaki, Akifumi Yamamoto, Kazutoh Takesako, Ken Yamaguchi, Yasuto Akiyama

Pages: 1131-1138 Published online on: 07 August 2012
Open Access

BreastDefend™ prevents breast-to-lung cancer metastases in an orthotopic animal model of triple-negative human breast cancer

Jiahua Jiang, Anita Thyagarajan-Sahu, Jagadish Loganathan, Isaac Eliaz, Colin Terry, George E. Sandusky, Daniel Sliva

Pages: 1139-1145 Published online on: 26 July 2012
Open Access

Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells

Kenta Masuda, Kouji Banno, Megumi Yanokura, Kosuke Tsuji, Yusuke Kobayashi, Iori Kisu, Arisa Ueki, Wataru Yamagami, Hiroyuki Nomura, Eiichiro Tominaga, Nobuyuki Susumu, Daisuke Aoki

Pages: 1146-1152 Published online on: 13 July 2012
Open Access

Silencing of the hTERT gene through RNA interference induces apoptosis via bax/bcl-2 in human glioma cells

Tuo Wang, Yan Xue, Maode Wang, Qiang Sun

Pages: 1153-1158 Published online on: 06 August 2012
Open Access

Role of the angiogenic components, VEGFA, FGF2, OPN and RHOC, in urothelial cell carcinoma of the urinary bladder

Apostolos Zaravinos, Dimitrios Volanis, George I. Lambrou, Dimitris Delakas, Demetrios A. Spandidos

Pages: 1159-1166 Published online on: 03 August 2012
Open Access

Anti-angiogenic and antitumor activities of Huaier aqueous extract

Xiaolong Wang, Ning Zhang, Qiang Huo, Qifeng Yang

Pages: 1167-1175 Published online on: 08 August 2012

Cannabinoids inhibit peptidoglycan-induced phosphorylation of NF-κB and cell growth in U87MG human malignant glioma cells

Ryosuke Echigo, Naotoshi Sugimoto, Akihiro Yachie, Takako Ohno-Shosaku

Pages: 1176-1180 Published online on: 26 July 2012

Investigation of proNT/NMN secretion from small cell lung carcinoma cells using a mouse xenograft model

Kanako Wakabayashi-Nakao, Koji Maruyama, Hidee Ishii, Koji Muramatsu, Keiichi Hatakeyama, Keiichi Ohshima, Shun-Ichiro Ogura, Takashi Nakajima, Ken Yamaguchi, Tohru Mochizuki

Pages: 1181-1186 Published online on: 23 July 2012

KIF5B/RET fusion gene in surgically-treated adenocarcinoma of the lung

Keisuke Yokota, Hidefumi Sasaki, Katsuhiro Okuda, Shigeki Shimizu, Masayuki Shitara, Yu Hikosaka, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii

Pages: 1187-1192 Published online on: 13 July 2012

Antitumor activities of dFv-LDP-AE: An enediyne-energized fusion protein targeting tumor-associated antigen gelatinases

Gen-Shen Zhong, Min-Na Wu, Xiao-Fang Guo, Sheng-Hua Zhang, Qing-Fang Miao, Yong-Su Zhen

Pages: 1193-1199 Published online on: 13 July 2012

Expression of the mitotic-arrest deficiency 2 is associated with chemotherapy resistance in ovarian serous adenocarcinoma

Yusuke Nakano, Toshiyuki Sumi, Masatomo Teramae, Masanari Morishita, Takeshi Fukuda, Hiroyuki Terada, Hiroyuki Yoshida, Yoshinari Matsumoto, Tomoyo Yasui, Osamu Ishiko

Pages: 1200-1204 Published online on: 12 July 2012

Molecular detection of cryptic Y-chromosomal material in patients with Turner syndrome

Elva I. Cortés-Gutiérrez, Rosalba Herrera-Bartolo, Martha I. Dávila-Rodríguez, Gerardo C. Palacios-Saucedo, Javier Vargas-Villarreal, Juana B. Romero-Villarreal

Pages: 1205-1210 Published online on: 16 July 2012

Breast MALT lymphomas: A clinicopathological and cytogenetic study of 9 cases

Giuseppina Liguori, Monica Cantile, Margherita Cerrone, Elvira La Mantia, Maurizio Di Bonito, Fabrizio Zanconati, Maria Pia Curcio, Gabriella Aquino, Anna La Mura, Rosa Giannatiempo, Annarosaria De Chiara, Angela Lombardi, Gerardo Botti, Antonio D'Antonio, Michele Caraglia, Renato Franco

Pages: 1211-1216 Published online on: 27 July 2012

The mobilization, recruitment and contribution of bone marrow-derived endothelial progenitor cells to the tumor neovascularization occur at an early stage and throughout the entire process of hepatocellular carcinoma growth

Haitao Zhu, Qianwen Shao, Xitai Sun, Zhengming Deng, Xianwen Yuan, Decai Yu, Xiang Zhou, Yitao Ding

Pages: 1217-1224 Published online on: 31 July 2012

A somatic TSHR mutation in a patient with lung adenocarcinoma with bronchioloalveolar carcinoma, coronary artery disease and severe chronic obstructive pulmonary disease

James Wan Soo Kim, Sharon Lee, Natalie Lui, Helen Choi, Michael Mulvihill, Li Tai Fang, Hio Chung Kang, Yong-Won Kwon, David Jablons, Il-Jin Kim

Pages: 1225-1230 Published online on: 26 July 2012

High Wilms' tumor 1 mRNA expression correlates with basal-like and ERBB2 molecular subtypes and poor prognosis of breast cancer

Xiao-Wei Qi, Fan Zhang, Xin-Hua Yang, Lin-Jun Fan, Yi Zhang, Yan Liang, Lin Ren, Ling Zhong, Qing-Qiu Chen, Kong-Yong Zhang, Wei-Dong Zang, Li-Shan Wang, Ying Zhang, Jun Jiang

Pages: 1231-1236 Published online on: 12 July 2012

Expression of miRNA-146a in nasopharyngeal carcinoma is upregulated by Epstein-Barr virus latent membrane protein 1

Yinghai Zhao, Xiaoyi Chen, Min Jing, Haijun Du, Yi Zeng

Pages: 1237-1242 Published online on: 25 July 2012

Microwave-induced thermoablation with Amica-probe is a safe and reproducible method to treat solid renal masses: Results from a phase I study

Riccardo Bartoletti, Enrico Meliani, Alchiede Simonato, Paolo Gontero, Giovanna Berta, Paolo Dalla Palma, Elena Leonardi, Tommaso Cai, Giorgio Carmignani

Pages: 1243-1248 Published online on: 06 August 2012

A predicted miR-27a-mediated network identifies a signature of glioma

Shuxu Yang, Kun Wang, Cong Qian, Zhengfei Song, Peiyu Pu, Anling Zhang, Wei Wang, Huanjiang Niu, Xinwei Li, Xuchen Qi, Yinxin Zhu, Yirong Wang

Pages: 1249-1256 Published online on: 07 August 2012

Role of trefoil factor 1 in gastric cancer and relationship between trefoil factor 1 and gastrokine 1

Wei Mao, Jie Chen, Tie-Li Peng, Xiao-Fei Yin, Lian-Zhou Chen, Min-Hu Chen

Pages: 1257-1262 Published online on: 27 July 2012

Overexpression of the structural maintenance of chromosome 4 protein is associated with tumor de-differentiation, advanced stage and vascular invasion of primary liver cancer

Bo Zhou, Tao Yuan, Menggang Liu, Hongming Liu, Jun Xie, Yanbin Shen, Ping Chen

Pages: 1263-1268 Published online on: 24 July 2012

Suppression of heat shock protein 27 expression promotes 5-fluorouracil sensitivity in colon cancer cells in a xenograft model

Ryohei Hayashi, Yoshiyuki Ishii, Hiroki Ochiai, Atsushi Matsunaga, Takashi Endo, Hirotoshi Hasegawa, Yuko Kitagawa

Pages: 1269-1274 Published online on: 25 July 2012

Human 5-, 12- and 15-lipoxygenase-1 coexist in kidney but show opposite trends and their balance changes in cancer

Amira Gohara, Noha Eltaki, Dina Sabry, Daniel Murtagh , Jerzy Jankun, Steven H. Selman, Ewa Skrzypczak-Jankun

Pages: 1275-1282 Published online on: 20 July 2012

Fatty acid-binding protein 5 promotes cell proliferation and invasion in human intrahepatic cholangiocarcinoma

Chi-Young Jeong, Young-Sool Hah, Bok Im Cho, Seon Min Lee, Young-Tae Joo, Eun-Jung Jung, Sang-Ho Jeong, Young-Joon Lee, Sang-Kyung Choi, Woo-Song Ha, Soon-Tae Park, Soon-Chan Hong

Pages: 1283-1292 Published online on: 19 July 2012

Upregulation of miR-20a and miR-106b is involved in the acquisition of malignancy of pediatric brainstem gliomas

Xuan Wang, Hongwei Zhang, Anling Zhang, Lei Han, Kun Wang, Ran Liu, Shaohua Yang, Peiyu Pu, Changhong Shen, Chunsheng Kang, Chunjiang Yu

Pages: 1293-1300 Published online on: 23 July 2012

Evaluation of CD44 and CD133 as cancer stem cell markers for colorectal cancer

Chunxia Wang, Jingping Xie, Jiasong Guo, H. Charles Manning, John C. Gore, Ning Guo

Pages: 1301-1308 Published online on: 06 August 2012

Intensity-modulated stereotactic radiotherapy for the treatment of medically inoperable patients with NSCLC stage I

Stephan Lächelt, Markus Alber, Matthias Söhn, Michael  Bamberg, Volker Steger, Martin Weinmann

Pages: 1309-1314 Published online on: 07 August 2012

Adenovirus-mediated ING4/IL-24 double tumor suppressor gene co-transfer enhances antitumor activity in human breast cancer cells

Yaodong Zhao, Zhengyi Li, Weihua Sheng, Jingchen Miao, Jicheng Yang

Pages: 1315-1324 Published online on: 24 July 2012

B ultrasound-guided hyperthermic intraperitoneal perfusion chemotherapy for the treatment of malignant ascites

Shuzhong Cui, Mingchen Ba, Yunqiang Tang, Jifang Liu, Yinbing Wu, Bin Wang, Xiangliang Zhang, Hongsheng Tang, Shizhen Zhong

Pages: 1325-1331 Published online on: 13 July 2012

AAV2-mediated gene transfer of VEGF-Trap with potent suppression of primary breast tumor growth and spontaneous pulmonary metastases by long-term expression

Lian Lu, Shun-Tao Luo, Hua Shan Shi, Meng Li, Hai Long Zhang, Sha Sha He, Yan Liu, Ying Pan, Li Yang

Pages: 1332-1338 Published online on: 16 July 2012

Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells

Jianteng Wei, Haizhou Liu, Ming Liu, Ning Wu, Jin Zhao, Lin Xiao, Lijun Han, Edward Chu, Xiukun Lin

Pages: 1339-1345 Published online on: 19 July 2012

miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect

Yan Sun, Xiaoping Zhao, Yuhong Zhou, Yu Hu

Pages: 1346-1352 Published online on: 08 August 2012

The molecular mechanism of luteolin-induced apoptosis is potentially related to inhibition of angiogenesis in human pancreatic carcinoma cells

Xueting Cai, Wuguang Lu, Tingmei Ye, Min Lu, Jianhua Wang, Jiege Huo, Shihui Qian, Xiaoning Wang, Peng Cao

Pages: 1353-1361 Published online on: 16 July 2012

Suppression of tumor invasion and migration in breast cancer cells following delivery of siRNA against Stat3 with the antimicrobial peptide PR39

Wenxia Tian, Bing Li, Xiwen Zhang, Weiqi Dang, Xiaofei Wang, Hao Tang, Lin Wang, Hong Cao, Tingmei Chen

Pages: 1362-1368 Published online on: 13 July 2012

Involvement of ROS in the inhibitory effect of thermotherapy combined with chemotherapy on A549 human lung adenocarcinoma cell growth through the Akt pathway

Lin Wang, Xinkui Liu, Yongjun Wu, Weidong Wu, Yiming Wu

Pages: 1369-1375 Published online on: 07 August 2012

Rotenone induces KATP channel opening in PC12 cells in association with the expression of tyrosine hydroxylase

Qunhua Bai, Junlin He, Jingfu Qiu, Yang Wang, Shibo Wang, Yun Xiu, Chao Yu

Pages: 1376-1384 Published online on: 08 August 2012

Immortalized mouse fetal liver stromal cells support growth and maintenance of human embryonic stem cells

Jiabo Hu, Sanqiang Hu, Quanhui Ma, Xiaohui Wang, Zhongwei Zhou, Wei Zhang, Xiaochun Sun, Wei Zhu, Hui Qian, Wenrong Xu

Pages: 1385-1391 Published online on: 13 July 2012

Decreased expression of the carboxyl terminus of heat shock cognate 70 interacting protein in human gastric cancer and its clinical significance

Lei Gan, Dong-Bo Liu, Hai-Feng Lu, Guo-Xian Long, Qi Mei, Guang-Yuan Hu, Hong Qiu, Guo-Qing Hu

Pages: 1392-1398 Published online on: 08 August 2012

Ikaros inhibits proliferation and, through upregulation of Slug, increases metastatic ability of ovarian serous adenocarcinoma cells

Li-Cai He, Feng-Hou Gao, Han-Zhang Xu, Shan Zhao, Chun-Min Ma, June Li, Shu Zhang, Ying-Li Wu

Pages: 1399-1405 Published online on: 02 August 2012

Enhanced cytotoxic effect of low doses of metformin combined with ionizing radiation on hepatoma cells via ATP deprivation and inhibition of DNA repair

Jifang Liu, Min Hou, Taize Yuan, Gao Yi, Shuxu Zhang, Xunfan Shao, Jinhui Chen, Xiaoting Jia, Zhimin He

Pages: 1406-1412 Published online on: 25 July 2012

Heterogeneous data fusion for brain tumor classification

Vangelis Metsis, Heng Huang, Ovidiu C. Andronesi, Fillia Makedon, Aria Tzika

Pages: 1413-1416 Published online on: 25 July 2012

Genetic alterations of WWOX in Wilms' tumor are involved in its carcinogenesis

Elżbieta Płuciennik, Magdalena Nowakowska, Wioletta I. Wujcicka, Anna Sitkiewicz, Bernarda Kazanowska, Elżbieta Zielińska, Andrzej K. Bednarek

Pages: 1417-1422 Published online on: 27 July 2012

Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro

Michael Saugspier, Christoph Dorn, Barbara Czech, Manfred Gehrig, Jörg Heilmann, Claus Hellerbrand

Pages: 1423-1428 Published online on: 20 July 2012

Pro-apoptotic role of the MEK/ERK pathway in ursodeoxycholic acid-induced apoptosis in SNU601 gastric cancer cells

Sung-Chul Lim, Hong-Quan Duong, Keshab Raj Parajuli, Song Iy Han

Pages: 1429-1434 Published online on: 19 July 2012

Induction of apoptosis and reduction of MMP gene expression in the U373 cell line by polyphenolics in Aronia melanocarpa and by curcumin

Noor Azela Abdullah Thani, Benjamin Sallis, Robert Nuttall, Frank R. Schubert, Mansoor Ahsan, Derek Davies, Sukhveer Purewal, Alan Cooper, Harcharan K. Rooprai

Pages: 1435-1442 Published online on: 27 July 2012

Serum interleukin-15 levels in cancer patients with cachexia

Pedro L. Martínez-Hernández, Ángel Hernanz-Macías, Carmen Gómez-Candela, Cristina Grande-Aragón, Jaime Feliu-Batlle, Javier Castro-Carpeño, Isabel Martínez-Muñoz, Laura Zurita-Rosa, Marta Villarino-Sanz, Concepción Prados-Sánchez, Joaquín Sánchez García-Girón

Pages: 1443-1452 Published online on: 23 July 2012

Inhibition of hepatocellular carcinoma cell growth by an anti-insulin-like growth factor-I receptor monoclonal antibody

Lu Yue, Ying Wang, Huamao Wang, Huiping Gao, Jun Liang, Aihua Sui, Jinyu Xiang, Fang Zhou, Congcong Xu, Wenwen Zhao, Wanhua Liang, Ruyong Yao

Pages: 1453-1460 Published online on: 08 August 2012

MRS study of meningeal hemangiopericytoma and edema: A comparison with meningothelial meningioma

Valeria Righi, Vitaliano Tugnoli, Adele Mucci, Antonella Bacci, Sergio Bonora, Luisa Schenetti

Pages: 1461-1467 Published online on: 19 July 2012

SGEF is overexpressed in prostate cancer and contributes to prostate cancer progression

Hongtao Wang, Ruiqin Wu, Lan Yu, Feima Wu, Shanhu Li, Yali Zhao, Hailiang Li, Guolan Luo, Jian Wang, Jianguang Zhou

Pages: 1468-1474 Published online on: 19 July 2012

Enforced expression of RASAL1 suppresses cell proliferation and the transformation ability of gastric cancer cells

Fengchang Qiao, Xianwei Su, Xuemei Qiu, Danwen Qian, Xiao Peng, Hong Chen, Zhujiang Zhao, Hong Fan

Pages: 1475-1481 Published online on: 19 July 2012

The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells

Yung-Yi Cheng, Jai-Sing Yang, Shih-Chang Tsai, Chih-Chuang Liaw, Jing-Gung Chung, Li-Jiau Huang, Kuo-Hsiung Lee, Chi-Cheng Lu, Hsi-Cheng Chien, Minoru Tsuzuki, Sheng-Chu Kuo

Pages: 1482-1490 Published online on: 19 July 2012

The influence of matriptase-2 on prostate cancer in vitro: A possible role for β-catenin

Siobhan L. Webb, Andrew J. Sanders, Malcolm D. Mason, Wen G. Jiang

Pages: 1491-1497 Published online on: 02 August 2012

MAGEA4 induces growth in normal oral keratinocytes by inhibiting growth arrest and apoptosis

Sheetal Bhan, Alice Chuang, Sandeep S. Negi, Chad A. Glazer, Joseph A. Califano

Pages: 1498-1502 Published online on: 25 July 2012

Prognostic impact of δ-like ligand 4 and Notch1 in acute myeloid leukemia

Jingru Zhang, Daoxin Ma, Jingjing Ye, Shaolei Zang, Fei Lu, Meixiang Yang, Xun Qu, Xiulian Sun, Chunyan Ji

Pages: 1503-1511 Published online on: 31 July 2012

Anti-neoplastic effects of fucoxanthin and its deacetylated product, fucoxanthinol, on Burkitt's and Hodgkin's lymphoma cells

Senji Tafuku, Chie Ishikawa, Takeshi Yasumoto, Naoki Mori

Pages: 1512-1518 Published online on: 03 August 2012

The ubiquitin-conjugating enzyme E2-EPF is overexpressed in cervical cancer and associates with tumor growth

Jing Liang, Hirotaka Nishi, Mei-Lu Bian, Chinatsu Higuma, Toru Sasaki, Hiroe Ito, Keiichi Isaka

Pages: 1519-1525 Published online on: 06 August 2012
Journal Cover

October 2012
Volume 28 Issue 4

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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