|
1
|
Tan ML, Ooi JP, Ismail N, Moad AI and
Muhammad TS: Programmed cell death pathways and current antitumor
targets. Pharm Res. 26:1547–1560. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wu GS: TRAIL as a target in anti-cancer
therapy. Cancer Lett. 285:1–5. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Deng Y, Lin Y and Wu X: TRAIL-induced
apoptosis requires Bax-dependent mitochondrial release of
Smac/DIABLO. Genes Dev. 16:33–45. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Sautour M, Mitaine-Offer AC, Miyamoto T,
Dongmo A and Lacaille-Dubois MA: A new steroidal saponin from
Dioscorea cayenensis. Chem Pharm Bull. 52:1353–1355. 2004.
View Article : Google Scholar
|
|
5
|
Wang Y, Che CM, Chiu JF and He QY: Dioscin
(saponin)-induced generation of reactive oxygen species through
mitochondria dysfunction: a proteomic-based study. J Proteome Res.
6:4703–4710. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Kaskiw MJ, Tassotto ML, Mok M, Tokar SL,
Pycko R, Th’ng J and Jiang ZH: Structural analogues of diosgenyl
saponins: synthesis and anticancer activity. Bioorg Med Chem.
17:7670–7679. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Lu B, Yin L, Xu L and Peng J: Application
of proteomic and bioinformatic techniques for studying the
hepatoprotective effect of dioscin against CCl4-induced
liver damage in mice. Planta Med. 77:407–415. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Cai J, Liu M, Wang Z and Ju Y: Apoptosis
induced by dioscin in HeLa cells. Biol Pharm Bull. 25:193–196.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Gao LL, Li FR, Jiao P, et al: Paris
chinensis dioscin induces G2/M cell cycle arrest and apoptosis in
human gastric cancer SGC-7901 cells. World J Gastroenterol.
17:4389–4395. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Wang Z, Zhou J, Ju Y, Zhang H, Liu M and
Li X: Effects of two saponins extracted from the polygonatum
Zanlanscianense pamp on the human leukemia (HL-60) cells. Biol
Pharm Bull. 24:159–162. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Zhiyu W, Yue C, Neng W, et al: Dioscin
induces cancer cell apoptosis through elevated oxidative stress
mediated by downregulation of peroxiredoxins. Cancer Biol Ther.
13:138–147. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kwon CS, Sohn HY, Kim SH, et al:
Anti-obesity effect of Dioscorea nipponica Makino with
lipase-inhibitory activity in rodents. Biosci Biotechnol Biochem.
67:1451–1456. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Sheng-Tanner X, Bump EA and Hedley DW: An
oxidative stress-mediated death pathway in irradiated human
leukemia cells mapped using multilaser flow cytometry. Radiat Res.
150:636–647. 1998. View
Article : Google Scholar
|
|
14
|
Choi YK, Seo HS, Choi HS, Choi HS, Kim SR,
Shin YC and Ko SG: Induction of Fas-mediated extrinsic apoptosis,
p21WAF1-related G2/M cell cycle arrest and ROS generation by
costunolide in estrogen receptor-negative breast cancer cells,
MDA-MB-231. Mol Cell Biochem. 363:119–128. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Son YG, Kim EH, Kim JY, et al: Silibinin
sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5
up-regulation and down-regulation of c-FLIP and survivin. Cancer
Res. 67:8274–8284. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kim YH, Jung EM, Lee TJ, et al:
Rosiglitazone promotes tumor necrosis factor-related
apoptosis-inducing ligand-induced apoptosis by reactive oxygen
species-mediated up-regulation of death receptor 5 and
down-regulation of c-FLIP. Free Radic Biol Med. 44:1055–1068. 2008.
View Article : Google Scholar
|
|
17
|
Kauh J, Fan S, Xia M, Yue P, Yang L, Khuri
FR and Sun SY: c-FLIP degradation mediates sensitization of
pancreatic cancer cells to TRAIL-induced apoptosis by the histone
deacetylase inhibitor LBH589. PLoS One. 5:e103762010. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Jang JH, Lee TJ, Yang ES, et al: Compound
C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis
through reactive oxygen species-mediated down-regulation of c-FLIPL
and Mcl-1. Exp Cell Res. 316:2194–2203. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Poukkula M, Kaunisto A, Hietakangas V, et
al: Rapid turnover of c-FLIPshort is determined by its unique
C-terminal tail. J Biol Chem. 280:27345–27355. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Kaunisto A, Kochin V, Asaoka T, Mikhailov
A, Poukkula M, Meinander A and Eriksson JE: PKC-mediated
phosphorylation regulates c-FLIP ubiquitylation and stability. Cell
Death Differ. 16:1215–1226. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Li W, Zhang X and Olumi AF: MG-132
sensitizes TRAIL-resistant prostate cancer cells by activating
c-Fos/c-Jun heterodimers and repressing c-FLIP(L). Cancer Res.
67:2247–2255. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Benayoun B, Baghdiguian S, Lajmanovich A,
et al: NF-kappaB-dependent expression of the antiapoptotic factor
c-FLIP is regulated by calpain 3, the protein involved in
limb-girdle muscular dystrophy type 2A. FASEB J. 22:1521–1529.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Glickman MH and Raveh D: Proteasome
plasticity. FEBS Lett. 579:3214–3223. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Nitobe J, Yamaguchi S, Okuyama M, et al:
Reactive oxygen species regulate FLICE inhibitory protein (FLIP)
and susceptibility to Fas-mediated apoptosis in cardiac myocytes.
Cardiovasc Res. 57:119–128. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kanayama A and Miyamoto Y: Apoptosis
triggered by phagocytosis-related oxidative stress through FLIPS
down-regulation and JNK activation. J Leukoc Biol. 82:1344–1352.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hu M, Xu L, Yin L, et al: Cytotoxicity of
dioscin in human gastric carcinoma cells through death receptor and
mitochondrial pathways. J Appl Toxicol. Feb 14–2012.(Epub ahead of
print).
|
