1
|
Schulte J and Littleton JT: The biological
function of the Huntingtin protein and its relevance to
Huntington’s Disease pathology. Curr Trends Neurol. 5:65–78.
2011.
|
2
|
Sorensen SA, Fenger K and Olsen JH:
Significantly lower incidence of cancer among patients with
Huntington disease: an apoptotic effect of an expanded
polyglutamine tract? Cancer. 86:1342–1346. 1999. View Article : Google Scholar
|
3
|
Kalchman MA, Koide HB, McCutcheon K, et
al: HIP1, a human homologue of S. cerevisiae Sla2p,
interacts with membrane-associated huntingtin in the brain. Nat
Genet. 16:44–53. 1997.PubMed/NCBI
|
4
|
Li XJ, Li SH, Sharp AH, et al: A
huntingtin-associated protein enriched in brain with implications
for pathology. Nature. 378:398–402. 1995. View Article : Google Scholar : PubMed/NCBI
|
5
|
Rao DS, Hyun TS, Kumar PD, et al:
Huntingtin-interacting protein 1 is overexpressed in prostate and
colon cancer and is critical for cellular survival. J Clin Invest.
110:351–360. 2002. View Article : Google Scholar : PubMed/NCBI
|
6
|
Rao DS, Bradley SV, Kumar PD, et al:
Altered receptor trafficking in Huntingtin Interacting Protein
1-transformed cells. Cancer Cell. 3:471–482. 2003. View Article : Google Scholar : PubMed/NCBI
|
7
|
Marcora E and Kennedy MB: The Huntington’s
disease mutation impairs Huntingtin’s role in the transport of
NF-kappaB from the synapse to the nucleus. Hum Mol Genet.
19:4373–4384. 2010.
|
8
|
Gutekunst CA, Li SH, Yi H, Ferrante RJ, Li
XJ and Hersch SM: The cellular and subcellular localization of
huntingtin-associated protein 1 (HAP1): comparison with huntingtin
in rat and human. J Neurosci. 18:7674–7686. 1998.PubMed/NCBI
|
9
|
Cape A, Chen X, Wang CE, et al: Loss of
huntingtin-associated protein 1 impairs insulin secretion from
pancreatic β-cells. Cell Mol Life Sci. 69:1305–1317. 2012.
|
10
|
Yang GZ, Yang M, Lim Y, et al: Huntingtin
associated protein 1 regulates trafficking of the amyloid precursor
protein and modulates amyloid beta levels in neurons. J Neurochem.
122:1010–1022. 2012. View Article : Google Scholar : PubMed/NCBI
|
11
|
Yuen EY, Wei J, Zhong P and Yan Z:
Disrupted GABAAR trafficking and synaptic inhibition in a mouse
model of Huntington’s disease. Neurobiol Dis. 46:497–502.
2012.PubMed/NCBI
|
12
|
Li SH, Yu ZX, Li CL, et al: Lack of
huntingtin-associated protein-1 causes neuronal death resembling
hypothalamic degeneration in Huntington’s disease. J Neurosci.
23:6956–6964. 2003.PubMed/NCBI
|
13
|
Takeshita Y, Fujinaga R, Zhao C, Yanai A
and Shinoda K: Huntingtin-associated protein 1 (HAP1) interacts
with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced
apoptosis. Hum Mol Genet. 15:2298–2312. 2006. View Article : Google Scholar : PubMed/NCBI
|
14
|
Galluzzi L, Kepp O and Kroemer G:
Caspase-3 and prostaglandins signal for tumor regrowth in cancer
therapy. Oncogene. 31:2805–2808. 2012. View Article : Google Scholar : PubMed/NCBI
|
15
|
Huang Q, Li F, Liu X, et al: Caspase
3-mediated stimulation of tumor cell repopulation during cancer
radiotherapy. Nat Med. 17:860–866. 2011. View Article : Google Scholar : PubMed/NCBI
|
16
|
Li J, Pandey V, Kessler T, Lehrach H and
Wierling C: Modeling of miRNA and drug action in the EGFR signaling
pathway. PLoS One. 7:e301402012. View Article : Google Scholar : PubMed/NCBI
|
17
|
Yano S, Kondo K, Yamaguchi M, et al:
Distribution and function of EGFR in human tissue and the effect of
EGFR tyrosine kinase inhibition. Anticancer Res. 23:3639–3650.
2003.PubMed/NCBI
|
18
|
Islam MN, Fujinaga R, Yanai A, et al:
Characterization of the ‘sporadically lurking HAP1-immunoreactive
(SLH) cells’ in the hippocampus, with special reference to the
expression of steroid receptors, GABA, and progenitor cell markers.
Neuroscience. 210:67–81. 2012.
|
19
|
Bosanac I, Alattia JR, Mal TK, et al:
Structure of the inositol 1,4,5-trisphosphate receptor binding core
in complex with its ligand. Nature. 420:696–700. 2002. View Article : Google Scholar
|
20
|
Tang TS, Tu H, Chan EY, et al: Huntingtin
and huntingtin associated protein 1 influence neuronal calcium
signaling mediated by inositol-(1,4,5) triphosphate receptor type
1. Neuron. 39:227–239. 2003. View Article : Google Scholar : PubMed/NCBI
|
21
|
Kopil CM, Siebert AP, Kevin FJ and Neumar
RW: Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor
impairs ER Ca(2+) buffering and causes neurodegeneration in primary
cortical neurons. J Neurochem. 123:147–158. 2012.PubMed/NCBI
|
22
|
Storr SJ, Lee KW, Woolston CM, et al:
Calpain system protein expression in basal-like and triple-negative
invasive breast cancer. Ann Oncol. 23:2289–2296. 2012. View Article : Google Scholar : PubMed/NCBI
|
23
|
Mataga MA, Rosenthal S, Heerboth S, et al:
Anti-breast cancer effects of histone deacetylase inhibitors and
calpain inhibitor. Anticancer Res. 32:2523–2529. 2012.PubMed/NCBI
|
24
|
Chua BT, Guo K and Li P: Direct cleavage
by the calcium-activated protease calpain can lead to inactivation
of caspases. J Biol Chem. 275:5131–5135. 2000. View Article : Google Scholar : PubMed/NCBI
|