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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May 2013 Volume 29 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

PARP1 gene expression is downregulated by knockdown of PARG gene

Fumiaki Uchiumi, Takeshi Watanabe, Ryo Ohta, Hideaki Abe, Sei-Ichi Tanuma
Pages: 1683-1688
Published online on: 04 March 2013

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Article Open Access

Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Pages: 1689-1696
Published online on: 26 February 2013

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Article Open Access

Sequence mutations of the substrate binding pocket of stem cell factor and multidrug resistance protein ABCG2 in renal cell cancer: A possible link to treatment resistance

Inka Zoernig, Claudia Ziegelmeier, Bernd Lahrmann, Niels  Grabe, Dirk Jäger, Niels Halama
Pages: 1697-1700
Published online on: 05 March 2013

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Article Open Access

Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation

Zujun Sun, Shuiqing Hu, Qingqiong Luo, Dongxia Ye, Dan Hu, Fuxiang Chen
Pages: 1701-1706
Published online on: 01 March 2013

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Article Open Access

Efficacy of goserelin plus anastrozole in premenopausal women with advanced or recurrent breast cancer refractory to an LH-RH analogue with tamoxifen: Results of the JMTO BC08-01 phase II trial

Reiki Nishimura, Keisei Anan, Yutaka Yamamoto, Kenji Higaki, Maki  Tanaka, Kenji Shibuta, Yasuaki Sagara, Shinji Ohno, Shigeru  Tsuyuki, Takahiro Mase, Satoshi Teramukai
Pages: 1707-1713
Published online on: 27 February 2013

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Article Open Access

Inhibition of the SK-N-MC human neuroblastoma cell line in vivo and in vitro by a novel nutrient mixture

M. Waheed Roomi, Tatiana Kalinovsky, Nusrath W. Roomi, Aleksandra Niedzwiecki, Matthias Rath
Pages: 1714-1720
Published online on: 27 February 2013

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Article Open Access

RNA interference-mediated FANCF silencing sensitizes OVCAR3 ovarian cancer cells to adriamycin through increased adriamycin-induced apoptosis dependent on JNK activation Corrigendum in /10.3892/or.2022.8327

Miao He, Hai-Gang Sun, Jun-Ying Hao, Yan-Lin Li, Jian-Kun Yu, Yuan-Yuan Yan, Lin Zhao, Na Li, Yan Wang, Xue-Feng Bai, Zhao-Jin Yu, Zhi-Hong Zheng, Xiao-Yi Mi, En-Hua Wang, Min-Jie Wei
Pages: 1721-1729
Published online on: 21 February 2013

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Article Open Access

Expression of HAUSP in gliomas correlates with disease progression and survival of patients

Chuandong Cheng, Chaoshi Niu, Yang Yang, Yang Wang, Manman Lu
Pages: 1730-1736
Published online on: 12 March 2013

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Article

The expression and function of Toll-like receptors 3 and 9 in human colon carcinoma

Keiichiro Nojiri, Kazushi Sugimoto, Katsuya Shiraki, Masahiko Tameda, Yuuji Inagaki, Satoko Kusagawa, Suguru Ogura, Junichiro Tanaka, Misao Yoneda, Norihiko Yamamoto, Hiroshi Okano, Yoshiyuki Takei, Masaaki Ito, Chika Kasai, Hidekazu Inoue, Koujiro Takase
Pages: 1737-1743
Published online on: 04 March 2013

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Article

Antiproliferative activity of gambogic acid isolated from Garcinia hanburyi in Hep3B and Huh7 cancer cells

Parry Ngan Hon Lee, Wing Shing Ho
Pages: 1744-1750
Published online on: 19 February 2013

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Article

Low-dose dacarbazine-doxorubicin therapy against intra-abdominal desmoid tumors

Hirofumi Yamamoto, Ryota Oshiro, Junichi Nishimura, Mamoru Uemura, Naotsugu Haraguchi, Taishi Hata, Ichiro Takemasa, Tsunekazu Mizushima, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori
Pages: 1751-1755
Published online on: 13 March 2013

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Article

Clinical impact of tumor-infiltrating CD45RO+ memory T cells on human gastric cancer

Kohei Wakatsuki, Masayuki Sho, Ichiro Yamato, Tomoyoshi Takayama, Sohei Matsumoto, Tetsuya Tanaka, Kazuhiro Migita, Masahiro Ito, Kiyohiko Hotta, Yoshiyuki Nakajima
Pages: 1756-1762
Published online on: 22 February 2013

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Article

Prognostic value of cancer stem cells, epithelial-mesenchymal transition and circulating tumor cells in lung cancer

G. Pirozzi, V. Tirino, R. Camerlingo, A. La Rocca, N. Martucci, G. Scognamiglio, R. Franco, M. Cantile, N. Normanno, G. Rocco
Pages: 1763-1768
Published online on: 19 February 2013

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Article

miRNA-181b increases the sensitivity of pancreatic ductal adenocarcinoma cells to gemcitabine in vitro and in nude mice by targeting BCL-2

Baobao Cai, Yong An, Nan Lv, Jianmin Chen, Min Tu, Jie Sun, Pengfei Wu, Jishu Wei, Kuirong Jiang, Yi Miao
Pages: 1769-1776
Published online on: 21 February 2013

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Article

ALDH1-positive cancer stem-like cells are enriched in nodal metastases of oropharyngeal squamous cell carcinoma independent of HPV status

Xu Qian, Steffen Wagner, Chenming Ma, Jens P. Klussmann, Michael Hummel, Andreas M. Kaufmann, Andreas E. Albers
Pages: 1777-1784
Published online on: 11 March 2013

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Article

Inhibition of Cdk2 activity decreases Aurora-A kinase centrosomal localization and prevents centrosome amplification in breast cancer cells

Alexey A. Leontovich, Jeffrey L. Salisbury, Massimiliano Veroux, Tiziano Tallarita, Daniel Billadeau, James McCubrey, James Ingle, Evanthia Galanis, Antonino B. D'Assoro
Pages: 1785-1788
Published online on: 27 February 2013

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Article

Morpho-physiological heterogeneity of cells within two rat prostate carcinoma cell lines AT-2 and MAT-LyLu differing in the degree of malignancy observed by cell cloning and the effects of caffeine, theophylline and papaverine upon a proportion of the clones

Ewa Musialik, Damian Ryszawy, Zbigniew Madeja, Wlodzimierz Korohoda
Pages: 1789-1796
Published online on: 05 March 2013

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Article

Lentiviral-mediated gene silencing of Notch-4 inhibits in vitro proliferation and perineural invasion of ACC-M cells

Wei Chen, Huali Zhang, Jiandong Wang, Gang Cao, Zhen Dong, Han Su, Xiaojun Zhou, Senlin Zhang
Pages: 1797-1804
Published online on: 28 February 2013

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Article

Copper induces cellular senescence in human glioblastoma multiforme cells through downregulation of Bmi-1

Yuan Li, Jifan Hu, Fangxia Guan, Laijun Song, Ruitai Fan, Huaijie Zhu, Xiang Hu, Eileen Shen, Bo Yang
Pages: 1805-1810
Published online on: 06 March 2013

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Article

Metastasin leads to poor prognosis of hepatocellular carcinoma through partly inducing EMT

Xin Zheng, Xiaohong Gai, Zhenhua Wu, Qingguang Liu, Yingmin Yao
Pages: 1811-1818
Published online on: 12 March 2013

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Article

Genome-wide analysis of DNA methylation in tongue squamous cell carcinoma

Sheng Zhang, Xiang-Ling Feng, Lei Shi, Chao-Jian Gong, Zhi-Jing He, Han-Jiang Wu, Tian-You Ling
Pages: 1819-1826
Published online on: 27 February 2013

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Article

Analysis of genomic aberrations associated with the clinicopathological parameters of rectal cancer by array‑based comparative genomic hybridization

Jian-Wei Liang, Zhi-Zhou Shi, Tong-Tong Zhang, Jia-Jie Hao, Zheng Wang, Xiao-Min Wang, Hai Yang, Ming-Rong Wang, Zhi-Xiang Zhou, Yu Zhang
Pages: 1827-1834
Published online on: 21 February 2013

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Article

4-hexylresorcinol exerts antitumor effects via suppression of calcium oscillation and its antitumor effects are inhibited by calcium channel blockers

Seong-Gon Kim, Je-Yong Choi
Pages: 1835-1840
Published online on: 19 February 2013

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Article

Cytokine-induced killer cells co-cultured with complete tumor antigen-loaded dendritic cells, have enhanced selective cytotoxicity on carboplatin-resistant retinoblastoma cells

Ya-Feng Wang, Patricia E. Kunda, Jian-Wei Lin, Han Wang, Xue-Mei Chen, Qiu-Ling Liu, Tao Liu
Pages: 1841-1850
Published online on: 28 February 2013

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Article

Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells

Qin Du, Bing Hu, Hong-Mei An, Ke-Ping Shen, Ling Xu, Shan Deng, Meng-Meng Wei
Pages: 1851-1858
Published online on: 27 February 2013

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Article

Livistona chinensis seed suppresses hepatocellular carcinoma growth through promotion of mitochondrial-dependent apoptosis

Wei Lin, Jinyan Zhao, Zhiyun Cao, Qunchuan Zhuang, Liangpu Zheng, Qiaoyan Cai, Daxin Chen, Lili Wang, Zhenfeng Hong, Jun Peng
Pages: 1859-1866
Published online on: 01 March 2013

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Article

Core binding factor acute myeloid leukaemia and c-KIT mutations

Ludovica Riera, Filippo Marmont, Daniela Toppino, Chiara  Frairia, Francesca  Sismondi, Ernesta Audisio, Cristiana Di Bello, Stefano  D'Ardia, Paola  Francia Di Celle, Emanuela Messa, Giorgio Inghirami, Umberto Vitolo, Achille Pich
Pages: 1867-1872
Published online on: 05 March 2013

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Article

Progesterone inhibits the migration and invasion of A549 lung cancer cells through membrane progesterone receptor α-mediated mechanisms

Mingxuan Xie, Shaojin You, Qiong Chen, Xi Chen, Chengping Hu
Pages: 1873-1880
Published online on: 06 March 2013

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Article

Huntingtin-associated protein 1: A potential biomarker of breast cancer

Liwei Zhu, Xue Song, Jinhai Tang, Jianzhong Wu, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Zhuo Wang
Pages: 1881-1887
Published online on: 22 February 2013

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Article

Heparanase is involved in the proliferation and invasion of nasopharyngeal carcinoma cells

Jinzhang Chen, Dayong Zheng, Jie Shen, Jian Ruan, Aimin Li, Wenmin Li, Guozhu Xie, Xiaojun Luo, Peng Zhao, Hang Zheng
Pages: 1888-1894
Published online on: 05 March 2013

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Article

Inhibition of extracellular signal-regulated kinase activity by sorafenib increases sensitivity to DNR in K562 cells

Ruo-Zhi Xiao, Cheng-Ming He, Mu-Jun Xiong, Xing-Xing Ruan, Li-Lin Wang, Yan Chen, Dong-Jun Lin
Pages: 1895-1901
Published online on: 06 March 2013

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Article

Gene expression profiling and molecular pathway analysis for the identification of early-stage lung adenocarcinoma patients at risk for early recurrence

Hisashi Saji, Masahiro Tsuboi, Yoshihisa Shimada, Yasufumi Kato, Wakako Hamanaka, Yujin Kudo, Koichi Yoshida, Jun Matsubayashi, Jitsuo Usuda, Tatsuo Ohira, Norihiko Ikeda
Pages: 1902-1906
Published online on: 06 March 2013

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Article

Impact of acetylsalicylic acid on tumor angiogenesis and lymphangiogenesis through inhibition of VEGF signaling in a murine sarcoma model

Xiaoyue Zhang, Zhaopeng Wang, Zhaoxia Wang, Yueying Zhang, Qing Jia, Licun Wu, Weidong Zhang
Pages: 1907-1913
Published online on: 11 March 2013

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Article

High susceptibility of heterozygous (+/fa) lean Zucker rats to 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis

Toshio Imai, Young-Man Cho, Mami Takahashi, Tsukasa Kitahashi, Shigeaki Takami, Akiyoshi Nishikawa, Kumiko Ogawa
Pages: 1914-1922
Published online on: 05 March 2013

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Article

Sorting, identification and enrichment of side population cells in THP-1 acute monocytic leukemia cells

Yingchao Wang, Chuyun Yin, Lei Feng, Lina Ma, Yongwei Wei, Guangyao Sheng
Pages: 1923-1931
Published online on: 28 February 2013

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Article

miRNA-22 suppresses colon cancer cell migration and invasion by inhibiting the expression of T-cell lymphoma invasion and metastasis 1 and matrix metalloproteinases 2 and 9

Bo Li, Yan Song, Tong-Jun Liu, You-Bin Cui, Yang Jiang, Zhong-Shi Xie, Shu-Li Xie
Pages: 1932-1938
Published online on: 22 February 2013

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Article

Study of the mechanisms underlying the reversal of multidrug resistance of human neuroblastoma multidrug-resistant cell line SK-N-SH/MDR1 by low-intensity pulsed ultrasound

Yanhui Sun, Qin Li, Youhua Xu, Conglun Pu, Lihua Zhao, Zhenhua Guo, Xionghui Ding, Xianqing Jin
Pages: 1939-1945
Published online on: 07 March 2013

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Article

Low methylation levels of the SFRP1 gene are associated with the basal-like subtype of breast cancer

Young Ju Jeong, Hye Yeon Jeong, Jin Gu Bong, Sung Hwan Park, Hoon Kyu Oh
Pages: 1946-1954
Published online on: 06 March 2013

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Article

Peptide FLNPDVLDI of heparanase is a novel HLA-A2-restricted CTL epitope and elicits potent immunological antitumor effects in vitro with an 8-branched design

Jun Zhang, Jianmin Yang, Daiming Fan, Houquan Tao, Huiju Wang, Tong Yu
Pages: 1955-1961
Published online on: 13 March 2013

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Human papillomavirus infection in head and neck cancer: The role of the secretory leukocyte protease inhibitor

Markus Hoffmann, Elgar S. Quabius, Silke Tribius, Lena Hebebrand, Tibor Görögh, Gordana Halec, Tomas Kahn, Jürgen Hedderich, Christoph Röcken, Jochen Haag, Tim Waterboer, Markus Schmitt, Anna R. Giuliano, W. Martin Kast
Pages: 1962-1968
Published online on: 05 March 2013

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Article

Prognostic and therapeutic implications of mTORC1 and Rictor expression in human breast cancer

U. Wazir, R. F. Newbold, W. G. Jiang, A. K. Sharma, K. Mokbel
Pages: 1969-1974
Published online on: 13 March 2013

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Article

Blockade of DNA methylation enhances the therapeutic effect of gefitinib in non-small cell lung cancer cells

Xiao-You Li, Jian-Zhong Wu, Hai-Xia Cao, Rong Ma, Jian-Qiu Wu, Yue-Jiao Zhong, Ji-Feng Feng
Pages: 1975-1982
Published online on: 21 February 2013

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Article

Epigallocatechin gallate promotes p53 accumulation and activity via the inhibition of MDM2-mediated p53 ubiquitination in human lung cancer cells

Longyu Jin, Cui Li, Yan Xu, Li Wang, Jianxin Liu, Dianjun Wang, Cao  Hong, Zhibing Jiang, Yuchao Ma, Qian Chen, Fenglei Yu
Pages: 1983-1990
Published online on: 12 March 2013

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Article

Identification of plant extracts sensitizing breast cancer cells to TRAIL

Sherif Abdelhamed, Satoru Yokoyama, Lia Hafiyani, Surya K. Kalauni, Yoshihiro Hayakawa, Suresh Awale, Ikuo Saiki
Pages: 1991-1998
Published online on: 19 February 2013

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Article

Cyclooxygenase-2 is induced by p38 MAPK and promotes cell survival

Rosanna Parente, Elisabetta Trifirò, Francesca Cuozzo, Sandro Valia, Mara Cirone, Livia Di Renzo
Pages: 1999-2004
Published online on: 27 February 2013

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Article

Prevalence of underlying lung disease in smokers with epidermal growth factor receptor-mutant lung cancer

Akimasa Sekine, Katsumi Tamura, Hiroaki Satoh, Tomoaki Tanaka, Yoshiya Tsunoda, Toru Tanaka, Hiroyuki Takoi, Shih-Yuan Lin, Yohei Yatagai, Toshinori Hashizume, Kenji Hayasihara, Takefumi Saito
Pages: 2005-2010
Published online on: 01 March 2013

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Article

A novel c-Met inhibitor, MK8033, synergizes with carboplatin plus paclitaxel to inhibit ovarian cancer cell growth

Douglas C. Marchion, Elona Bicaku, Yin Xiong, Nadim Bou Zgheib, Entidhar Al Sawah, Xiaomang Ba Stickles, Patricia L. Judson, Alex S. Lopez, Christopher L. Cubitt, Jesus Gonzalez-Bosquet, Robert M. Wenham, Sachin M. Apte, Anders Berglund, Johnathan M. Lancaster
Pages: 2011-2018
Published online on: 05 March 2013

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Article

miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells

Yonghua Xu, Yong An, Yun Wang, Changhe Zhang, Hai Zhang, Changjun Huang, Hao Jiang, Xuehao Wang, Xiangcheng Li
Pages: 2019-2024
Published online on: 07 March 2013

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Article

Zinc-α2-glycoprotein: A proliferative factor for breast cancer? In vitro study and molecular mechanisms

Laetitia Delort, Stéphane Perrier, Virginie Dubois, Hermine Billard, Tomas Mracek, Chen Bing, Marie-Paule Vasson, Florence Caldefie-Chézet
Pages: 2025-2029
Published online on: 27 February 2013

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Article

Genetic inhibition of vascular endothelial growth factor receptor-1 significantly inhibits the migration and proliferation of leukemia cells and increases their sensitivity to chemotherapy

Bing Xiu, Wenjun Zhang, Binbin Huang, Jingde Chen, Huina Lu, Jianfei Fu, Hong Xiong, Aibin Liang
Pages: 2030-2038
Published online on: 13 March 2013

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Article

Effect of histone deacetylase and DNA methyltransferase inhibitors on the expression of the androgen receptor gene in androgen-independent prostate cancer cell lines

Barbora Fialova, Katerina Smesny Trtkova, Lenka Paskova, Katerina Langova, Zdenek Kolar
Pages: 2039-2045
Published online on: 13 March 2013

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Article

Downregulation of microRNA-138 enhances the proliferation, migration and invasion of cholangiocarcinoma cells through the upregulation of RhoC/p-ERK/MMP-2/MMP-9

Qi Wang, Huihuan Tang, Shanshan Yin, Chao Dong
Pages: 2046-2052
Published online on: 26 February 2013

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Article

Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose

Hiroshi Miwa, Masato Shikami, Mineaki Goto, Shohei Mizuno, Miyuki Takahashi, Norikazu Tsunekawa-Imai, Takamasa Ishikawa, Motonori Mizutani, Tomohiro Horio, Mayuko Gotou, Hidesuke Yamamoto, Motohiro Wakabayashi, Masaya Watarai, Ichiro Hanamura, Akira Imamura, Hidetsugu Mihara, Masakazu Nitta
Pages: 2053-2057
Published online on: 21 February 2013

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Article

Melatonin modulates aromatase activity and expression in endothelial cells

Virginia Alvarez-García, Alicia González, Carlos Martínez-Campa, Carolina Alonso-González, Samuel Cos
Pages: 2058-2064
Published online on: 28 February 2013

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Promising anti-leukemic activity of atorvastatin

Jolanta D. Żołnierczyk, Arleta Borowiak, Paweł Hikisz, Barbara Cebula-Obrzut, Jerzy Z. Błoński, Piotr Smolewski, Tadeusz Robak, Zofia M. Kiliańska
Pages: 2065-2071
Published online on: 22 February 2013

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Indirubin-3'-monoxime promotes autophagic and apoptotic death in JM1 human acute lymphoblastic leukemia cells and K562 human chronic myelogenous leukemia cells

Ming-Yang Lee, Yi-Wen Liu, Ming-Ho Chen, Jin-Yi Wu, Hsing‑Ying  Ho, Qwa-Fun Wang, Jing-Jing Chuang
Pages: 2072-2078
Published online on: 06 March 2013

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Let-7: A regulator of the ERα signaling pathway in human breast tumors and breast cancer stem cells

Xin Sun, Sida Qin, Chong Fan, Chongwen Xu, Ning Du, Hong Ren
Pages: 2079-2087
Published online on: 06 March 2013

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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