|
1
|
Louis DN, Ohgaki H, Wiestler OD, et al:
The 2007 WHO classification of tumours of the central nervous
system. Acta Neuropathol. 114:97–109. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ohgaki H, Dessen P, Jourde B, et al:
Genetic pathways to glioblastoma: a population-based study. Cancer
Res. 64:6892–6899. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Stupp R, Mason WP, van den Bent MJ, et al:
Radiotherapy plus concomitant and adjuvant temozolomide for
glioblastoma. N Engl J Med. 352:987–996. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Stupp R, Hegi ME, Mason WP, et al: Effects
of radiotherapy with concomitant and adjuvant temozolomide versus
radiotherapy alone on survival in glioblastoma in a randomised
phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet
Oncol. 10:459–466. 2009.
|
|
5
|
Stupp R, Hegi ME, Gilbert MR and
Chakravarti A: Chemoradiotherapy in malignant glioma: standard of
care and future directions. J Clin Oncol. 25:4127–4136. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Ohgaki H and Kleihues P: Population-based
studies on incidence, survival rates, and genetic alterations in
astrocytic and oligodendroglial gliomas. J Neuropathol Exp Neurol.
64:479–489. 2005.PubMed/NCBI
|
|
7
|
Bruggeman SW, Hulsman D, Tanger E, et al:
Bmi-1 controls tumor development in an Ink4a/Arf-independent manner
in a mouse model for glioma. Cancer Cell. 12:328–341. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Cancer Genome Atlas Research Network.
Comprehensive genomic characterization defines human glioblastoma
genes and core pathways. Nature. 455:1061–1068. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ohgaki H and Kleihues P: Genetic
alterations and signaling pathways in the evolution of gliomas.
Cancer Sci. 100:2235–2241. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Hwang ES, Yoon G and Kang HT: A
comparative analysis of the cell biology of senescence and aging.
Cell Mol Life Sci. 66:2503–2524. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Nakahara Y, Shiraishi T, Okamoto H, et al:
Detrended fluctuation analysis of genome-wide copy number profiles
of glioblastomas using array-based comparative genomic
hybridization. Neuro Oncol. 6:281–289. 2004. View Article : Google Scholar
|
|
12
|
Gupta A and Lutsenko S: Human copper
transporters: mechanism, role in human diseases and therapeutic
potential. Future Med Chem. 1:1125–1142. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Valko M, Morris H and Cronin MT: Metals,
toxicity and oxidative stress. Curr Med Chem. 12:1161–1208. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Gaetke LM and Chow CK: Copper toxicity,
oxidative stress, and antioxidant nutrients. Toxicology.
189:147–163. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Barnham KJ and Bush AI: Metals in
Alzheimer’s and Parkinson’s diseases. Curr Opin Chem Biol.
12:222–228. 2008.
|
|
16
|
Brewer GJ: Risks of copper and iron
toxicity during aging in humans. Chem Res Toxicol. 23:319–326.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Matos L, Gouveia A and Almeida H: Copper
ability to induce premature senescence in human fibroblasts. Age.
34:783–794. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Dimri GP, Lee X, Basile G, et al: A
biomarker that identifies senescent human cells in culture and in
aging skin in vivo. Proc Natl Acad Sci USA. 92:9363–9367. 1995.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Bradford MM: A rapid and sensitive method
for the quantitation of microgram quantities of protein utilizing
the principle of protein-dye binding. Anal Biochem. 72:248–254.
1976. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Galli R, Binda E, Orfanelli U, et al:
Isolation and characterization of tumorigenic, stem-like neural
precursors from human glioblastoma. Cancer Res. 64:7011–7021. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Hemmati HD, Nakano I, Lazareff JA, et al:
Cancerous stem cells can arise from pediatric brain tumors. Proc
Natl Acad Sci USA. 100:15178–15183. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Singh SK, Hawkins C, Clarke ID, et al:
Identification of human brain tumour initiating cells. Nature.
432:396–401. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Simon JA and Tamkun JW: Programming off
and on states in chromatin: mechanisms of Polycomb and trithorax
group complexes. Curr Opin Genet Dev. 12:210–218. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Orlando V: Polycomb, epigenomes, and
control of cell identity. Cell. 112:599–606. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Lessard J, Baban S and Sauvageau G:
Stage-specific expression of polycomb group genes in human bone
marrow cells. Blood. 91:1216–1224. 1998.PubMed/NCBI
|
|
26
|
Park IK, Qian D, Kiel M, et al: Bmi-1 is
required for maintenance of adult self-renewing haematopoietic stem
cells. Nature. 423:302–305. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Molofsky AV, Pardal R, Iwashita T, Park
IK, Clarke MF and Morrison SJ: Bmi-1 dependence distinguishes
neural stem cell self-renewal from progenitor proliferation.
Nature. 425:962–967. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Abdouh M, Facchino S, Chatoo W, Balasingam
V, Ferreira J and Bernier G: Bmi-1 sustains human glioblastoma
multiforme stem cell renewal. J Neurosci. 29:8884–8896. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Vonlanthen S, Heighway J, Altermatt HJ, et
al: The bmi-1 oncoprotein is differentially expressed in non-small
cell lung cancer and correlates with INK4A-ARF locus expression. Br
J Cancer. 84:1372–1376. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kim JH, Yoon SY, Jeong SH, et al:
Overexpression of Bmi-1 oncoprotein correlates with axillary lymph
node metastases in invasive ductal breast cancer. Breast.
13:383–388. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Leung C, Lingbeek M, Shakhova O, et al:
Bmi-1 is essential for cerebellar development and is overexpressed
in human medulloblastomas. Nature. 428:337–341. 2004. View Article : Google Scholar : PubMed/NCBI
|
