|
1
|
Grossman SA and Batara JF: Current
management of glioblastoma multiforme. Semin Oncol. 31:635–644.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Nieder C, Andratschke N, Wiedenmann N,
Busch R, Grosu AL and Molls M: Radiotherapy for high-grade gliomas.
Does altered fractionation improve the outcome? Strahlenther Onkol.
180:401–407. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Reya T, Morrison SJ, Clarke MF and
Weissman IL: Stem cells, cancer, and cancer stem cells. Nature.
414:105–111. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Marx J: Cancer research. Mutant stem cells
may seed cancer. Science. 301:1308–1310. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Clarke MF, Dick JE, Dirks PB, Eaves CJ,
Jamieson CH, Jones DL, Visvader J, Weissman IL and Wahl GM: Cancer
stem cells - perspectives on current status and future directions:
AACR Workshop on cancer stem cells. Cancer Res. 66:9339–9344. 2006.
View Article : Google Scholar
|
|
6
|
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q,
Hjelmeland AB, Dewhirst MW, Bigner DD and Rich JN: Glioma stem
cells promote radioresistance by preferential activation of the DNA
damage response. Nature. 444:756–760. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
McCord AM, Jamal M, Williams ES,
Camphausen K and Tofilon PJ: CD133+ glioblastoma
stem-like cells are radiosensitive with a defective DNA damage
response compared with established cell lines. Clin Cancer Res.
15:5145–5153. 2009.
|
|
8
|
Tichý A, Vávrová J, Pejchal J and Rezácová
M: Ataxia-telangiectasia mutated kinase (ATM) as a central
regulator of radiation-induced DNA damage response. Acta Medica
(Hradec Kralove). 53:13–17. 2010.PubMed/NCBI
|
|
9
|
Bower JJ, Zhou Y, Zhou T, Simpson DA,
Arlander SJ, Paules RS, Cordeiro-Stone M and Kaufmann WK: Revised
genetic requirements for the decatenation G2 checkpoint: the role
of ATM. Cell Cycle. 9:1617–1628. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Banin S, Moyal L, Shieh S, Taya Y,
Anderson CW, Chessa L, Smorodinsky NI, Prives C, Reiss Y, Shiloh Y
and Ziv Y: Enhanced phosphorylation of p53 by ATM in response to
DNA damage. Science. 281:1674–1677. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Matsuoka S, Huang M and Elledge SJ:
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Science. 282:1893–1897. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Jiang H, Reinhardt HC, Bartkova J,
Tommiska J, Blomqvist C, Nevanlinna H, Bartek J, Yaffe MB and
Hemann MT: The combined status of ATM and p53 link tumor
development with therapeutic response. Genes Dev. 23:1895–1909.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Ignatova TN, Kukekov VG, Laywell ED,
Suslov ON, Vrionis FD and Steindler DA: Human cortical glial tumors
contain neural stem-like cells expressing astroglial and neuronal
markers in vitro. Glia. 39:193–206. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Singh SK, Clarke ID, Terasaki M, Bonn VE,
Hawkins C, Squire J and Dirks PB: Identification of a cancer stem
cell in human brain tumors. Cancer Res. 63:5821–5828.
2003.PubMed/NCBI
|
|
15
|
Kondo T, Setoguchi T and Taga T:
Persistence of a small subpopulation of cancer stem-like cells in
the C6 glioma cell line. Proc Natl Acad Sci USA. 101:781–786. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Li G, Chen Z, Hu YD, Wei H, Li D, Ji H and
Wang DL: Autocrine factors sustain glioblastoma stem cell
self-renewal. Oncol Rep. 21:419–424. 2009.PubMed/NCBI
|
|
17
|
Li GH, Wei H, Lv SQ, Ji H and Wang DL:
Knockdown of STAT3 expression by RNAi suppresses growth and induces
apoptosis and differentiation in glioblastoma stem cells. Int J
Oncol. 37:103–110. 2010.PubMed/NCBI
|
|
18
|
Blazek ER, Foutch JL and Maki G: Daoy
medulloblastoma cells that express CD133 are radioresistant
relative to CD133− cells, and the CD133+
sector is enlarged by hypoxia. Int J Radiat Oncol Biol Phys.
67:1–5. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Diehn M and Clarke MF: Cancer stem cells
and radiotherapy: new insights into tumor radioresistance. J Natl
Cancer Inst. 98:1755–1757. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Singh NP, McCoy MT, Tice RR and Schneider
EL: A simple technique for quantitation of low levels of DNA damage
in individual cells. Exp Cell Res. 175:184–191. 1988. View Article : Google Scholar
|
|
21
|
Ng WL, Yan D, Zhang X, Mo YY and Wang Y:
Over-expression of miR-100 is responsible for the low-expression of
ATM in the human glioma cell line: M059J. DNA Repair. 9:1170–1175.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Allalunis-Turner MJ, Barron GM, Day RS
III, Dobler KD and Mirzayans R: Isolation of two cell lines from a
human malignant glioma specimen differing in sensitivity to
radiation and chemotherapeutic drugs. Radiat Res. 134:349–354.
1993. View
Article : Google Scholar : PubMed/NCBI
|
|
23
|
Choi S, Gamper AM, White JS and Bakkenist
CJ: Inhibition of ATM kinase activity does not phenocopy ATM
protein disruption: implications for the clinical utility of ATM
kinase inhibitors. Cell Cycle. 9:4052–4057. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kennedy RD and D’Andrea AD: DNA repair
pathways in clinical practice: lessons from pediatric cancer
susceptibility syndromes. J Clin Oncol. 24:3799–3808. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Shiloh Y: ATM and related protein kinases:
safeguarding genome integrity. Nat Rev Cancer. 3:155–168. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Canman CE, Wolff AC, Chen CY, Fornace AJ
Jr and Kastan MB: The p53-dependent G1 cell cycle checkpoint
pathway and ataxia-telangiectasia. Cancer Res. 54:5054–5058.
1994.PubMed/NCBI
|
|
27
|
Rainey MD, Charlton ME, Stanton RV and
Kastan MB: Transient inhibition of ATM kinase is sufficient to
enhance cellular sensitivity to ionizing radiation. Cancer Res.
68:7466–7474. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
White JS, Choi S and Bakkenist CJ:
Transient ATM kinase inhibition disrupts DNA damage-induced sister
chromatid exchange. Sci Signal. 3:ra442010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Kastan MB, Onyekwere O, Sidransky D,
Vogelstein B and Craig RW: Participation of p53 protein in the
cellular response to DNA damage. Cancer Res. 51:6304–6311.
1991.PubMed/NCBI
|
