Journal Articles
Review
Rationale for the design of an oncology trial using a generic targeted therapy multi‑drug regimen for NSCLC patients without treatment options (Review)
Stefan Langhammer
Pages: 1535-1541 Published online on: 22 July 2013
Article
STK10 missense mutations associated with anti-apoptotic function
Kazutaka Fukumura, Yoshihiro Yamashita, Masahito Kawazu, Eirin Sai, Shin-Ichiro Fujiwara, Naoya Nakamura, Kengo Takeuchi, Mizuo Ando, Kohei Miyazono, Toshihide Ueno, Keiya Ozawa, Hiroyuki Mano
Pages: 1542-1548 Published online on: 09 July 2013
Article
Myeloid leukemia with t(7;21)(p22;q22) and 5q deletion
Ioannis Panagopoulos, Ludmila Gorunova, Petter Brandal, Margaret Garnes, Anne Tierens, Sverre Heim
Pages: 1549-1552 Published online on: 18 July 2013
Article
Novel insulin receptor substrate 1 and 2 variants in breast and colorectal cancer
Diana Liberata Esposito, Fabio Verginelli, Sonia Toracchio, Sandra Mammarella, Laura De Lellis, Cinzia Vanni, Antonio Russo, Renato Mariani-Costantini, Alessandro Cama
Pages: 1553-1560 Published online on: 18 July 2013
Article
Evaluation of eligibility criteria in living donor liver transplantation for hepatocellular carcinoma by α-SMA-positive cancer-associated fibroblasts
Hiroyuki Takamura, Shinichi Nakanuma, Hironori Hayashi, Hidehiro Tajima, Kaheita Kakinoki, Seisyo Sakai, Isamu Makino, Hisatoshi Nakagawara, Tomoharu Miyashita, Koichi Okamoto, Keishi Nakamura, Katunobu Oyama, Masashi Inokuchi, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Ichiro Ohnishi, Masato Kayahara, Takashi Tani, Kuniaki Arai, Taro Yamashita, Tatsuya Yamashita, Hoshiko Kitamura, Hiroko Ikeda, Shuichi Kaneko, Yasuni Nakanuma, Osamu Matsui, Tetsuo Ohta
Pages: 1561-1574 Published online on: 16 July 2013
Article
Plasma osteopontin concentrations in patients with cutaneous melanoma
A. Filia, F. Elliott, T. Wind, S. Field, J. Davies, K. Kukalizch, J. Randerson-Moor, M. Harland, D. T. Bishop, R. E. Banks, J. A. Newton-Bishop
Pages: 1575-1580 Published online on: 08 August 2013
Article
A novel chemopreventive mechanism of selenomethionine: Enhancement of APE1 enzyme activity via a Gadd45a, PCNA and APE1 protein complex that regulates p53-mediated base excision repair
Hwa Jin Jung, Hye Lim Kim, Yeo Jin Kim, Jong-Il Weon, Young Rok Seo
Pages: 1581-1586 Published online on: 11 July 2013
Article
Effects of the monoamine oxidase inhibitors pargyline and tranylcypromine on cellular proliferation in human prostate cancer cells
Hyung Tae Lee, Mi Ran Choi, Mi Sook Doh, Kyoung Hwa Jung, Young Gyu Chai
Pages: 1587-1592 Published online on: 24 July 2013
Article
Heparin-binding EGF-like growth factor enhances the activity of invasion and metastasis in thyroid cancer cells
Ichiro Ota, Shigeki Higashiyama, Takashi Masui, Katsunari Yane, Hiroshi Hosoi, Nariaki Matsuura
Pages: 1593-1600 Published online on: 06 August 2013
Article
S100A4 mRNA expression level is a predictor of radioresistance of pancreatic cancer cells
Shingo Kozono, Kenoki Ohuchida, Takao Ohtsuka, Lin Cui, Daiki Eguchi, Kenji Fujiwara, Ming Zhao, Kazuhiro Mizumoto, Masao Tanaka
Pages: 1601-1608 Published online on: 24 July 2013
Article
Analysis of protein expression regulated by lumican in PANC‑1 cells using shotgun proteomics
Tetsushi Yamamoto, Mitsuhiro Kudo, Wei-Xia Peng, Zenya Naito
Pages: 1609-1621 Published online on: 11 July 2013
Article
Overexpression of ERα inhibits proliferation and invasion of MKN28 gastric cancer cells by suppressing β-catenin
Jichun Zhou, Rongyue Teng, Chaoyang Xu, Qinchuan Wang, Jufeng Guo, Chenpu Xu, Ziduo Li, Shuduo Xie, Jianguo Shen, Linbo Wang
Pages: 1622-1630 Published online on: 09 July 2013
Article
Apoptosis induced by PGC-1β in breast cancer cells is mediated by the mTOR pathway
Libin Wang, Qilun Liu, Fang Li, Jing Qiu, Heng Fan, Haibin Ma, Yongzhao Zhu, Ligang Wu, Xuebo Han, Zhihong Yang, Haifeng Jiang, Jun Wei, Haibin Xia
Pages: 1631-1638 Published online on: 18 July 2013
Article
Overexpression of adenylate cyclase-associated protein 1 is associated with metastasis of lung cancer
Min Tan, Xiaolian Song, Guoliang Zhang, Aimei Peng, Xuan Li, Ming Li, Yang Liu, Changhui Wang
Pages: 1639-1644 Published online on: 09 July 2013
Article
Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid
Marissa D. Friedman, Dhruve S. Jeevan, Michael Tobias, Raj Murali, Meena Jhanwar-Uniyal
Pages: 1645-1650 Published online on: 18 July 2013
Article
Experimental hypothyroidism increases apoptosis in dimethylbenzanthracene-induced mammary tumors
Constanza Matilde López-Fontana, Corina Verónica Sasso, María Eugenia Maselli, Flavia Eliana Santiano, Silvana Noemí Semino, Fernando Darío Cuello Carrión , Graciela Alma Jahn, Rubén Walter Carón
Pages: 1651-1660 Published online on: 01 August 2013
Article
p53 is not related to Ki-67 immunostaining in the epithelial and mesenchymal components of female genital tract carcinosarcomas
Beata Bałon, Ewa Kaznowska, Atanas Ignatov, Anna Steć, Anna Semczuk-Sikora, Regine Schneider-Stock, Maciej Jóźwik, Stanisław Sulkowski, Marek Cybulski, Justyna Szumiło, Andrzej Semczuk
Pages: 1661-1668 Published online on: 11 July 2013
Article
Elevated expression of coactivator-associated arginine methyltransferase 1 is associated with early hepatocarcinogenesis
Shigehiro Osada, Shugo Suzuki, Chiaki Yoshimi, Miho Matsumoto, Tomoyuki Shirai, Satoru Takahashi, Masayoshi Imagawa
Pages: 1669-1674 Published online on: 02 August 2013
Article
CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma
Shun Matsuura, Kazuya Shinmura, Takaharu Kamo, Hisaki Igarashi, Kyoko Maruyama, Mari Tajima, Hiroshi Ogawa, Masayuki Tanahashi, Hiroshi Niwa, Kazuhito Funai, Takashi Kohno, Takafumi Suda, Haruhiko Sugimura
Pages: 1675-1680 Published online on: 19 July 2013
Article
Anticancer effects of Ac‑Phe‑Lys‑PABC‑doxorubicin via mitochondria‑centered apoptosis involving reactive oxidative stress and the ERK1/2 signaling pathway in MGC‑803 cells
Yan‑Jun Zhong, Shao‑Ping Liu, Raymond A. Firestone, Ya‑Ping Hong, Yan Li
Pages: 1681-1686 Published online on: 19 July 2013
Article
Significance of GSTP1 for predicting the prognosis and chemotherapeutic efficacy in esophageal squamous cell carcinoma
Yusuke Yamamoto, Hirotaka Konishi, Daisuke Ichikawa, Tomohiro Arita, Katsutoshi Shoda, Shuhei Komatsu, Atsushi Shiozaki, Hisashi Ikoma, Hitoshi Fujiwara, Kazuma Okamoto, Toshiya Ochiai, Jun Inoue, Johji Inazawa, Eigo Otsuji
Pages: 1687-1694 Published online on: 09 July 2013
Article
Application of POLARIC™ fluorophores in an in vivo tumor model
Nako Maishi, Taisuke Kawamoto, Noritaka Ohga, Koji Yamada, Kosuke Akiyama, Kazuyuki Yamamoto, Takahiro Osawa, Yasuhiro Hida, Kyoko Hida
Pages: 1695-1700 Published online on: 18 July 2013
Article
Pien Tze Huang inhibits tumor angiogenesis in a mouse model of colorectal cancer via suppression of multiple cellular pathways
Aling Shen, Jiumao Lin, Youqin Chen, Wei Lin, Liya Liu, Zhenfeng Hong, Thomas J. Sferra, Jun Peng
Pages: 1701-1706 Published online on: 09 July 2013
Article
Loss of p57 expression and RhoA overexpression are associated with poor survival of patients with hepatocellular carcinoma
Tinghua Hu, Hui Guo, Wenjuan Wang, Shuo Yu, Lili Han, Lili Jiang, Jiequn Ma, Chengcheng Yang, Qianqian Guo, Kejun Nan
Pages: 1707-1714 Published online on: 09 July 2013
Article
ADAM10 is overexpressed in human hepatocellular carcinoma and contributes to the proliferation, invasion and migration of HepG2 cells
Shao Yuan, Shi Lei, Shengli Wu
Pages: 1715-1722 Published online on: 02 August 2013
Article
Dihydroartemisinin inhibits tumor growth of human osteosarcoma cells by suppressing Wnt/β-catenin signaling
Yueliang Liu, Wenjuan Wang, Jing Xu, Li Li, Qian Dong, Qiong Shi, Guowei Zuo, Lan Zhou, Yaguang Weng, Min Tang, Tongchuan He, Jinyong Luo
Pages: 1723-1730 Published online on: 05 August 2013
Article
In vivo and in vitro inhibition of human liver cancer progress by downregulation of the μ-opioid receptor and relevant mechanisms
Jin Lu, Zefeng Liu, Lingling Zhao, Huimin Tian, Xiuhua Liu, Changji Yuan
Pages: 1731-1738 Published online on: 26 July 2013
Article
Inhibition of FOXM1 by thiostrepton sensitizes medulloblastoma to the effects of chemotherapy
Jiaping Lin, Yipeng Zheng, Kun Chen, Zhengsong Huang, Xinjian Wu, Nu Zhang
Pages: 1739-1744 Published online on: 02 August 2013
Article
Silencing tankyrase and telomerase promotes A549 human lung adenocarcinoma cell apoptosis and inhibits proliferation
Hongda Lu, Zhang Lei, Zhongxin Lu, Qianming Lu, Chi Lu, Weiqun Chen, Chun Wang, Qiu Tang, Qingzhi Kong
Pages: 1745-1752 Published online on: 08 August 2013
Article
CXCR4-mediated osteosarcoma growth and pulmonary metastasis is promoted by mesenchymal stem cells through VEGF
Peng Zhang, Ling Dong, Kang Yan, Hua Long, Tong-Tao Yang, Ming-Qing Dong, Yong Zhou, Qing-Yu Fan, Bao-An Ma
Pages: 1753-1761 Published online on: 17 July 2013
Article
CLC604 preferentially inhibits the growth of HER2-overexpressing cancer cells and sensitizes these cells to the inhibitory effect of Taxol in vitro and in vivo
Jang-Chang Lee, Li-Chen Chou, Jin-Chemg Lien, Jia-Chiun Wu, Chi-Hung Huang, Chao-Ho Chung, Fang-Yu Lee, Li-Jiau Huang, Sheng-Chu Kuo, Tzong-Der Way
Pages: 1762-1772 Published online on: 23 July 2013
Article
Potential antitumor agent from the endophytic fungus Pestalotiopsis photiniae induces apoptosis via the mitochondrial pathway in HeLa cells
Chuan Chen, Shu-Yuan Hu, Du-Qiang Luo, Si-Yu Zhu, Chuan-Qi Zhou
Pages: 1773-1781 Published online on: 17 July 2013
Article
Inhibition of the transcription factor Sp1 suppresses colon cancer stem cell growth and induces apoptosis in vitro and in nude mouse xenografts
Yingying Zhao, Wenjing Zhang, Zheng Guo, Feng Ma, Yao Wu, Yang Bai, Wei Gong, Ye Chen, Tianming Cheng, Fachao Zhi, Yali Zhang, Jide Wang, Bo Jiang
Pages: 1782-1792 Published online on: 18 July 2013
Article
Activation of the phosphorylation of ATM contributes to radioresistance of glioma stem cells
Wei Zhou, Mao Sun, Guang-Hui Li, Yong-Zhong Wu, Ying Wang, Fu Jin, Yun-Yun Zhang, Li Yang, Dong-Lin Wang
Pages: 1793-1801 Published online on: 11 July 2013
Article
Hypothyroidism in patients with colorectal carcinoma treated with fluoropyrimidines
Yutaka Fujiwara, Naoko Chayahara, Toru Mukohara, Naomi Kiyota, Hideo Tomioka, Yohei Funakoshi, Hironobu Minami
Pages: 1802-1806 Published online on: 30 July 2013
Article
ARC is highly expressed in nasopharyngeal carcinoma and confers X-radiation and cisplatin resistance
Ping Wu, Yaoyun Tang, Jian He, Lin Qi, Weihong Jiang, Suping Zhao
Pages: 1807-1813 Published online on: 18 July 2013
Article
Gene therapy for cancer through adenovirus vector‑mediated expression of the Ad5 early region gene 1A based on loss of IGF2 imprinting
Yuqin Pan, Bangshun He, Zhang Lirong, Zhenlin Nie, Liping Chen, Ling Gu, Andrew R. Hoffman, Shukui Wang, Jifan Hu
Pages: 1814-1822 Published online on: 30 July 2013
Article
Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells
Jing Zuo, Da-Hu Wang, Yu-Jun Zhang, Liang Liu, Feng-Ling Liu, Wei Liu
Pages: 1823-1831 Published online on: 01 August 2013
Article
Decreased miRNA-148a is associated with lymph node metastasis and poor clinical outcomes and functions as a suppressor of tumor metastasis in non-small cell lung cancer
Yong Chen, Lingfeng Min, Xizhi Zhang, Suwei Hu, Buhai Wang, Wei Liu, Rui Wang, Xuewen Gu, Weigan Shen, Houning Lv, Jing Zou, Yuexiang Chen, Xingxiang Xu, Longbang Chen
Pages: 1832-1840 Published online on: 09 July 2013
Article
CD176 antiserum treatment leads to a therapeutic response in a murine model of leukemia
Bin Yi, Zhe Zhang, Min Zhang, Reinhard Schwartz-Albiez, Yi Cao
Pages: 1841-1847 Published online on: 25 July 2013
Article
A novel human TINP1 gene promotes cell proliferation through inhibition of p53 and p21 expression
Wei Li, Ai-Ping Song, Fang Zhao, Yong-Mei Hu, Mu Hua
Pages: 1848-1852 Published online on: 01 August 2013
Article
Different regulatory pathways are involved in the proliferative inhibition of two types of leukemia cell lines induced by paclitaxel
Rui-Long Xia, Yan Lu, Li-Na Zhu, Shi-Fu Zhang, Fu-Kun Zhao, Cai-Yun Fu
Pages: 1853-1859 Published online on: 18 July 2013
Article
An osteopontin promoter polymorphism is associated with aggressiveness in breast cancer
Divya Ramchandani, Georg F. Weber
Pages: 1860-1868 Published online on: 23 July 2013
Article
Effect of β-carotene on cancer cell stemness and differentiation in SK-N-BE(2)C neuroblastoma cells
Hyun Ah Lee, Seolhyun Park, Yuri Kim
Pages: 1869-1877 Published online on: 30 July 2013
Article
Nuclear translocation of small G protein RhoA via active transportation in gastric cancer cells
Jin Xu, Yueying Li, Xiaoming Yang, Yongchang Chen, Min Chen
Pages: 1878-1882 Published online on: 25 July 2013
Article
Slit2 expression and its correlation with subcellular localization of β-catenin in gastric cancer
Rongliang Shi, Weiyan Liu, Bingya Liu, Ziping Xu, Liping Chen, Ziping Zhang
Pages: 1883-1889 Published online on: 07 August 2013
Article
NDRG2 positively regulates E-cadherin expression and prolongs overall survival in colon cancer patients
Young-Jun Kim, Ho-Bum Kang, Hyun Sun Yim, Joo Heon Kim, Jae Wha Kim
Pages: 1890-1898 Published online on: 29 July 2013
Article
Clinical implications of Ezrin and CD44 co‑expression in breast cancer
Lifang Ma, Tao Jiang
Pages: 1899-1905 Published online on: 26 July 2013
Article
Exome capture sequencing reveals new insights into hepatitis B virus-induced hepatocellular carcinoma at the early stage of tumorigenesis
Yong Chen, Lijuan Wang, Hexiang Xu, Xingxiang Liu, Yingren Zhao
Pages: 1906-1912 Published online on: 02 August 2013
Article
Combination of Ad-sTRAIL with the chemotherapeutic drug cisplatin synergistically enhances their pro-apoptotic ability in human breast cancer cells
Xiangping Liu, Jing Wang, Haibo Wang, Shihai Liu, Ye Liang, Zhidong Lv, Quan Zhou, Weili Ding
Pages: 1913-1919 Published online on: 02 August 2013
Article
Screening and identification of significant genes related to tumor metastasis and PSMA in prostate cancer using microarray analysis
Lin Xu, Zhu Wang, Xiao-Fei Li, Xia He, Lin-Lin Guan, Jiu-Ling Tuo, Yang Wang, Yanfen Luo, Hui-Ling Zhong, Shao-Peng Qiu, Kai-Yuan Cao
Pages: 1920-1928 Published online on: 05 August 2013
Article
Cytochalasin B induces apoptosis through the mitochondrial apoptotic pathway in HeLa human cervical carcinoma cells
Jiyoung Hwang, Myeongjin Yi, Xin Zhang, Yi Xu, Jee H. Jung, Dong-Kyoo Kim
Pages: 1929-1935 Published online on: 17 July 2013
Article
Modulation of the response of prostate cancer cell lines to cisplatin treatment using small interfering RNA
Eduardo Parra, Jorge Ferreira
Pages: 1936-1942 Published online on: 24 July 2013
Article
Expression and activation of P38 MAP kinase in invasive ductal breast cancers: Correlation with expression of the estrogen receptor, HER2 and downstream signaling phosphorylated proteins
Jean-Louis Merlin, Alexandre Harlé, Maëva Lion, Carole Ramacci, Agnès Leroux
Pages: 1943-1948 Published online on: 30 July 2013
Article
Identification of microRNAs in blood and urine as tumour markers for the detection of urinary bladder cancer
Angelika Tölle, Monika Jung, Silke Rabenhorst, Ergin Kilic, Klaus Jung, Steffen Weikert
Pages: 1949-1956 Published online on: 18 July 2013
Article
Specific role of JNK in the maintenance of the tumor-initiating capacity of A549 human non-small cell lung cancer cells
Masashi Okada, Keita Shibuya, Atsushi Sato, Shizuka Seino, Eriko Watanabe, Shuhei Suzuki, Manabu Seino, Chifumi Kitanaka
Pages: 1957-1964 Published online on: 02 August 2013
Article
Contribution of membrane progesterone receptor α to the induction of progesterone-mediated apoptosis associated with mitochondrial membrane disruption and caspase cascade activation in Jurkat cell lines
Asami Kon, Bo Yuan, Tomoyuki Hanazawa, Hidetomo Kikuchi, Mari Sato, Ryota Furutani, Norio Takagi, Hiroo Toyoda
Pages: 1965-1970 Published online on: 05 August 2013
Article
Loss of COP1 expression determines poor prognosisin patients with gastric cancer
Genta Sawada, Hiroki Ueo, Tae Matsumura, Ryutaro Uchi, Masahisa Ishibashi, Kosuke Mima, Junji Kurashige, Yusuke Takahashi, Sayuri Akiyoshi, Tomoya Sudo, Keishi Sugimachi, Yuichiro Doki, Masaki Mori, Koshi Mimori
Pages: 1971-1975 Published online on: 08 August 2013
Article
Epigenetic silencing of miR-126 contributes to tumor invasion and angiogenesis in colorectal cancer
Yu Zhang, Xinying Wang, Binghong Xu, Baocai Wang, Zhongqiu Wang, Yan Liang, Jieqiong Zhou, Jingjing Hu, Bo Jiang
Pages: 1976-1984 Published online on: 23 July 2013
Article
Epigenetic modifications of prostate-derived Ets transcription factor in breast cancer cells
Yamini Sabherwal, Nitin Mahajan, Ming Zhang
Pages: 1985-1988 Published online on: 06 August 2013
Article
Co-transduction of ribosomal protein L23 enhances the therapeutic efficacy of adenoviral-mediated p53 gene transfer in human gastric cancer
Ya-Fei Zhang, Bi-Cheng Zhang, An-Ran Zhang, Ting-Ting Wu, Jian Liu, Li-Fang Yu, Wei-Xing Wang, Jian-Fei Gao, Dian-Chun Fang, Zhi-Guo Rao
Pages: 1989-1995 Published online on: 07 August 2013
Article