1
|
Labokha AA, Gradmann S, Frey S, Hülsmann
BB, Urlaub H, Baldus M and Görlich D: Systematic analysis of
barrier-forming FG hydrogels from Xenopus nuclear pore complexes.
EMBO J. 23:204–218. 2013.PubMed/NCBI
|
2
|
Hetzer MW and Wente SR: Border control at
the nucleus: biogenesis and organization of the nuclear membrane
and pore complexes. Dev Cell. 17:606–616. 2009. View Article : Google Scholar : PubMed/NCBI
|
3
|
Mohr D, Frey S, Fischer T, Güttler T and
Görlich D: Characterisation of the passive permeability barrier of
nuclear pore complexes. EMBO J. 28:2541–2553. 2009. View Article : Google Scholar : PubMed/NCBI
|
4
|
Goldfarb DS, Corbett AH, Mason DA,
Harreman MT and Adam SA: Importin α: a multipurpose
nuclear-transport receptor. Trends Cell Biol. 14:505–514. 2004.
|
5
|
Sotiropoulos A, Gineitis D, Copeland J and
Treisman R: Signal-regulated activation of serum response factor is
mediated by changes in actin dynamics. Cell. 98:159–169. 1999.
View Article : Google Scholar : PubMed/NCBI
|
6
|
Kamai T, Yamanishi T, Shirataki H, Takagi
K, Asami H, Ito Y and Yoshida K: Overexpression of RhoA, Rac1, and
Cdc42 GTPases is associated with progression in testicular cancer.
Clin Cancer Res. 10:4799–4805. 2004. View Article : Google Scholar : PubMed/NCBI
|
7
|
Li Y, Chen Y, Tao Y, Xu J and Chen M: RhoA
protein is generally distributed in the nuclei of cancer cells.
Oncol Rep. 24:1005–1009. 2010.PubMed/NCBI
|
8
|
Dubash AD, Guilluy C, Srougi MC, Boulter
E, Burridge K and García-Mata R: The small GTPase RhoA localizes to
the nucleus and is activated by Net1 and DNA damage signals. PloS
One. 6:e173802011. View Article : Google Scholar : PubMed/NCBI
|
9
|
Guilluy C, Dubash AD and García-Mata R:
Analysis of RhoA and Rho GEF activity in whole cells and the cell
nucleus. Nat Protoc. 6:2050–2060. 2011. View Article : Google Scholar : PubMed/NCBI
|
10
|
Li Y, Chen Y and Xu J: Factors influencing
RhoA protein distribution in the nucleus. Mol Med Rep. 4:1115–1119.
2011.PubMed/NCBI
|
11
|
Okamoto T, Sanda T and Asamitsu K: NF-κB
signaling and carcinogenesis. Curr Pharm Des. 13:447–462. 2007.
|
12
|
Fagerlund R, Kinnunen L, Köhler M,
Julkunen I and Melén K: NF-{kappa}B is transported into the nucleus
by importin {alpha}3 and importin {alpha}4. J Biol Chem.
280:15942–15951. 2005.
|
13
|
Tonozuka Y, Minoshima Y, Bao YC, et al: A
GTPase-activating protein binds STAT3 and is required for
IL-6-induced STAT3 activation and for differentiation of a leukemic
cell line. Blood. 104:3550–3557. 2004. View Article : Google Scholar : PubMed/NCBI
|
14
|
Benitah SA, Valerón PF, van Aelst L,
Marshall CJ and Lacal JC: Rho GTPases in human cancer: an
unresolved link to upstream and downstream transcriptional
regulation. Biochim Biophys Acta. 1705:121–132. 2004.PubMed/NCBI
|
15
|
Riganti C, Doublier S, Costamagna C,
Aldieri E, Pescarmona G, Ghigo D and Bosia A: Activation of nuclear
factor-kappa B pathway by simvastatin and RhoA silencing increases
doxorubicin cytotoxicity in human colon cancer HT29 cells. Mol
Pharmacol. 74:476–484. 2008. View Article : Google Scholar : PubMed/NCBI
|
16
|
Chang HR, Huang HP, Kao YL, et al: The
suppressive effect of Rho kinase inhibitor, Y-27632, on oncogenic
Ras/RhoA induced invasion/migration of human bladder cancer TSGH
cells. Chem Biol Interact. 183:172–180. 2010. View Article : Google Scholar : PubMed/NCBI
|
17
|
Tao Y, Chen YC, Lan T, Qian H, Wang Y and
Jiang L: LPS-induced nuclear translocation of RhoA is dependent on
NF-κB in the human lung cancer cell line A549. Oncol Lett.
3:1283–1287. 2012.
|
18
|
Izaurralde E, Kutay U, von Kobbe C, Mattaj
IW and Görlich D: The asymmetric distribution of the constituents
of the Ran system is essential for transport into and out of the
nucleus. EMBO J. 16:6535–6547. 1997. View Article : Google Scholar : PubMed/NCBI
|
19
|
Lange A, Mills RE, Lange CJ, Stewart M,
Devine SE and Corbett AH: Classical nuclear localization signals:
definition, function, and interaction with importin alpha. J Biol
Chem. 282:5101–5105. 2007. View Article : Google Scholar : PubMed/NCBI
|
20
|
Sessler RJ and Noy N: A ligand-activated
nuclear localization signal in cellular retinoic acid binding
protein-II. Mol Cell. 18:343–353. 2005. View Article : Google Scholar : PubMed/NCBI
|
21
|
Greten FR and Karin M: The IKK/NF-κB
activation pathway - a target for prevention and treatment of
cancer. Cancer Lett. 206:193–199. 2004.
|
22
|
Turner JG, Dawson J and Sullivan DM:
Nuclear export of proteins and drug resistance in cancer. Biochem
Pharmacol. 83:1021–1032. 2012. View Article : Google Scholar : PubMed/NCBI
|
23
|
Fried H and Kutay U: Nucleocytoplasmic
transport: taking an inventory. Cell Mol Life Sci. 60:1659–1688.
2003. View Article : Google Scholar : PubMed/NCBI
|
24
|
Wolff B, Sanglier JJ and Wang Y:
Leptomycin B is an inhibitor of nuclear export: inhibition of
nucleo-cytoplasmic translocation of the human immunodeficiency
virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA. Chem Biol.
4:139–1347. 1997. View Article : Google Scholar : PubMed/NCBI
|
25
|
Ambrus G, Whitby LR, Singer EL, Trott O,
Choi E, Olson AJ, Boger DL and Gerace L: Small molecule
peptidomimetic inhibitors of importin α/β mediated nuclear
transport. Bioorg Med Chem. 18:7611–7620. 2010.PubMed/NCBI
|