|
1
|
Raghu G: Idiopathic pulmonary fibrosis:
guidelines for diagnosis and clinical management have advanced from
consensus-based in 2000 to evidence-based in 2011. Eur Respir J.
37:743–746. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wuyts WA, Agostini C, Antoniou K, et al:
The pathogenesis of pulmonary fibrosis: a moving target. Eur Respir
J. 41:1207–1218. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Calado RT and Young NS: Telomere diseases.
N Engl J Med. 361:2353–2365. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Vancheri C, Failla M, Crimi N and Raghu G:
Idiopathic pulmonary fibrosis: a disease with similarities and
links to cancer biology. Eur Respir J. 35:496–504. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Vancheri C and Du Bois RM: A
progression-free end-point for idiopathic pulmonary fibrosis
trials: lessons from cancer. Eur Respir J. 41:262–269. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Vancheri C: Idiopathic pulmonary fibrosis:
an altered fibroblast proliferation linked to cancer biology. Proc
Am Thorac Soc. 9:153–157. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Collins K and Mitchell JR: Telomerase in
the human organism. Oncogene. 21:564–579. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Fernandez-Garcia I, Ortiz-de-Solorzano C
and Montuenga LM: Telomeres and telomerase in lung cancer. J Thorac
Oncol. 3:1085–1088. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Broccoli D, Young JW and De Lange T:
Telomerase activity in normal and malignant hematopoietic cells.
Proc Natl Acad Sci USA. 92:9082–9086. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Wright WE, Piatyszek MA, Rainey WE, Byrd W
and Shay JW: Telomerase activity in human germline and embryonic
tissues and cells. Dev Genet. 18:173–179. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kim NW, Piatyszek MA, Prowse KR, et al:
Specific association of human telomerase activity with immortal
cells and cancer. Science. 266:2011–2015. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Diaz de Leon A, Cronkhite JT, Katzenstein
AL, et al: Telomere lengths, pulmonary fibrosis and telomerase
(TERT) mutations. PLoS One. 5:e106802010.PubMed/NCBI
|
|
13
|
American Thoracic Society. Idiopathic
pulmonary fibrosis: diagnosis and treatment. International
consensus statement. American Thoracic Society (ATS) and the
European Respiratory Society (ERS). Am J Respir Crit Care Med.
161:646–664. 2000. View Article : Google Scholar
|
|
14
|
Margaritopoulos GA, Antoniou KM, Soufla G,
Vassalou E, Spandidos DA and Siafakas NM: Yin Yang-1 (YY-1)
expression in idiopathic pulmonary fibrosis. J Recept Signal
Transduct Res. 31:188–191. 2011.PubMed/NCBI
|
|
15
|
Mehrad B, Burdick MD, Zisman DA, et al:
Circulating peripheral blood fibrocytes in human fibrotic
interstitial lung disease. Biochem Biophys Res Commun. 353:104–108.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Samara KD, Antoniou KM, Karagiannis K, et
al: Expression profiles of Toll-like receptors in non-small cell
lung cancer and idiopathic pulmonary fibrosis. Int J Oncol.
40:1397–1404. 2012.PubMed/NCBI
|
|
17
|
Antoniou KM, Soufla G, Proklou A, et al:
Different activity of the biological axis VEGF-Flt-1 (fms-like
tyrosine kinase 1) and CXC chemokines between pulmonary sarcoidosis
and idiopathic pulmonary fibrosis: a bronchoalveolar lavage study.
Clin Dev Immunol. 2009:5379292009. View Article : Google Scholar
|
|
18
|
Margaritopoulos GA, Antoniou KM,
Karagiannis K, et al: Investigation of Toll-like receptors in the
pathogenesis of fibrotic and granulomatous disorders: a
bronchoalveolar lavage study. Fibrogenesis Tissue Repair. 3:202010.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Antoniou KM, Soufla G, Lymbouridou R, et
al: Expression analysis of angiogenic growth factors and biological
axis CXCL12/CXCR4 axis in idiopathic pulmonary fibrosis. Connect
Tissue Res. 51:71–80. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Margaritopoulos GA, Romagnoli M, Poletti
V, Siafakas NM, Wells AU and Antoniou KM: Recent advances in the
pathogenesis and clinical evaluation of pulmonary fibrosis. Eur
Respir Rev. 21:48–56. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Lasithiotaki I, Antoniou KM, Derdas SP, et
al: The presence of merkel cell polyomavirus is associated with
deregulated expression of BRAF and Bcl-2 genes in non-small cell
lung cancer. Int J Cancer. 133:604–611. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Lasithiotaki I, Antoniou KM, Vlahava VM,
et al: Detection of herpes simplex virus type-1 in patients with
fibrotic lung diseases. PLoS One. 6:e278002011. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Antoniou KM, Margaritopoulos GA, Soufla G,
et al: Expression analysis of Akt and MAPK signaling pathways in
lung tissue of patients with idiopathic pulmonary fibrosis (IPF). J
Recept Signal Transduct Res. 30:262–269. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wang Y, Kuan PJ, Xing C, et al: Genetic
defects in surfactant protein A2 are associated with pulmonary
fibrosis and lung cancer. Am J Hum Genet. 84:52–59. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Tsakiri KD, Cronkhite JT, Kuan PJ, et al:
Adult-onset pulmonary fibrosis caused by mutations in telomerase.
Proc Natl Acad Sci USA. 104:7552–7557. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Diaz de Leon A, Cronkhite JT, Yilmaz C, et
al: Subclinical lung disease, macrocytosis, and premature graying
in kindreds with telomerase (TERT) mutations. Chest. 140:753–763.
2011.PubMed/NCBI
|
|
27
|
Flores I, Benetti R and Blasco MA:
Telomerase regulation and stem cell behaviour. Curr Opin Cell Biol.
18:254–260. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Lin SY and Elledge SJ: Multiple tumour
suppressor pathways negatively regulate telomerase. Cell.
113:881–889. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Alder JK, Chen JJ, Lancaster L, et al:
Short telomeres are a risk factor for idiopathic pulmonary
fibrosis. Proc Natl Acad Sci USA. 105:13051–13056. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Meyer KC, Raghu G, Baughman RP, et al; for
the American Thoracic Society Committee on BAL in Interstitial Lung
Disease. An official American Thoracic Society clinical practice
guideline: the clinical utility of bronchoalveolar lavage cellular
analysis in interstitial lung disease. Am J Respir Crit Care Med.
185:1004–1014. 2012. View Article : Google Scholar
|
|
31
|
Antoniou KM, Margaritopoulos GA, Proklou
A, et al: Investigation of telomerase/telomeres system in bone
marrow mesenchymal stem cells derived from IPF and RA-UIP. J
Inflamm (Lond). 9:272012. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Liu Z, Li Q, Li K, et al: Telomerase
reverse transcriptase promotes epithelial-mesenchymal transition
and stem cell-like traits in cancer cells. Oncogene. 32:4203–4213.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Samara KD, Tzortzaki EG, Neofytou E, et
al: Somatic DNA alterations in lung epithelial barrier cells in
COPD patients. Pulm Pharmacol Ther. 23:208–214. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Cronkhite JT, Xing C, Raghu G, et al:
Telomere shortening in familial and sporadic pulmonary fibrosis. Am
J Respir Crit Care Med. 178:729–737. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Antoniou KM, Papadaki HA, Soufla G and
Siafakas NM: Short telomeres and treatment of pulmonary fibrosis:
implications for early intervention. Am J Respir Crit Care Med.
179:9702009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Garcia CK: Idiopathic pulmonary fibrosis:
update on genetic discoveries. Proc Am Thorac Soc. 8:158–162. 2011.
View Article : Google Scholar : PubMed/NCBI
|
