Journal Articles

Open Access

Radical trachelectomy: The first step of fertility preservation in young women with cervical cancer (Review)

Salvatore Gizzo, Emanuele Ancona, Carlo Saccardi, Tito Silvio Patrelli, Roberto Berretta, Omar Anis, Marco Noventa, Anna Bertocco, Simone Fagherazzi, Michela Longone, Lucia Vendemiati, Donato D'Antona, Giovanni Battista Nardelli

Pages: 2545-2554 Published online on: 19 September 2013

The distinct mechanisms of the antitumor activity of emodin in different types of cancer (Review)

Wei-Tian Wei, Sheng-Zhang Lin, Dian-Lei Liu, Zhao-Hong Wang

Pages: 2555-2562 Published online on: 19 September 2013

The function of human epidermal growth factor receptor-3 and its role in tumors (Review)

Qin Li, Zhenyan Yuan, Bangwei Cao

Pages: 2563-2570 Published online on: 30 September 2013

FTY720 for cancer therapy (Review)

Li Zhang, Han-Dong Wang, Xiang-Jun Ji, Zi-Xiang Cong, Jian-Hong Zhu, Yuan Zhou

Pages: 2571-2578 Published online on: 01 October 2013
Open Access

Hyperexpression of HOXC13, located in the 12q13 chromosomal region, in well‑differentiated and dedifferentiated human liposarcomas

Monica Cantile, Francesca Galletta, Renato Franco, Gabriella Aquino, Giosuè Scognamiglio, Laura Marra, Margherita Cerrone, Gabriella Malzone, Angela Manna, Gaetano Apice, Flavio Fazioli, Gerardo Botti, Annarosaria De Chiara

Pages: 2579-2586 Published online on: 01 October 2013
Open Access

Cryptic FUS-ERG fusion identified by RNA-sequencing in childhood acute myeloid leukemia

Ioannis Panagopoulos, Ludmila Gorunova, Bernward Zeller, Anne Tierens, Sverre Heim

Pages: 2587-2592 Published online on: 25 September 2013
Open Access

The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis induction

Lenka Sucha, Milos Hroch, Martina Rezacova, Emil Rudolf, Radim Havelek, Ludek Sispera, Jana Cmielova, Renata Kohlerova, Ales Bezrouk, Pavel Tomsik

Pages: 2593-2602 Published online on: 02 October 2013
Open Access

Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model

Akira Noguchi, Keiji Kikuchi, Takashi Ohtsu, Mitsuyo Yoshiwara, Yoshiyasu Nakamura, Yohei Miyagi, Huachuan Zheng, Yasuo Takano

Pages: 2603-2608 Published online on: 02 October 2013
Open Access

New molecular staging with G-factors (VEGF-C and Reg IV) by supplementing TNM classification in colorectal cancers

Tetsuji Sawada, Masakazu Yashiro, Kazuhiro Sentani, Naohide Oue, Wataru Yasui, Kohji Miyazaki, Keita Kai, Hideto Fujita, Keishi Nakamura, Kiyoshi Maeda, Yoshihiro Kakeji, Shoji Natsugoe, Ken Shirabe, Sachiyo Nomura, Yutaka Shimada, Naohiro Tomita, Kosei Hirakawa, Yoshihiko Maehara

Pages: 2609-2616 Published online on: 03 October 2013
Open Access

Differential telomerase expression in idiopathic pulmonary fibrosis and non-small cell lung cancer

K. M. Antoniou, K. D. Samara, I. Lasithiotaki, G. A. Margaritopoulos, G. Soufla, I. Lambiri, I. Giannarakis, I. Drositis, D. A. Spandidos, N. M. Siafakas

Pages: 2617-2624 Published online on: 25 September 2013
Open Access

REG Iα gene expression is linked with the poor prognosis of lung adenocarcinoma and squamous cell carcinoma patients via discrete mechanisms

Michitaka Kimura, Hiroshi Naito, Takashi Tojo, Asako Itaya-Hironaka, Yoshiko Dohi, Mamiko Yoshimura, Kan-Ichi Nakagawara, Shin Takasawa, Shigeki Taniguchi

Pages: 2625-2631 Published online on: 19 September 2013
Open Access

Gender-dependent effects of gonadectomy on lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female and male A/J mice

Fumiko Ninomiya, Masanao Yokohira, Sosuke Kishi, Yuko Nakano, Keiko Yamakawa, Tatsushi Inoue, Toshiya Kuno, Katsumi Imaida

Pages: 2632-2638 Published online on: 01 October 2013

Sarcoglycans and integrins in bisphosphonate treatment: Immunohistochemical and scanning electron microscopy study

Francesco Saverio De Ponte, Angelo Favaloro, Enrico Nastro Siniscalchi, Antonio Centofanti, Michele Runci, Giuseppina Cutroneo, Luciano Catalfamo

Pages: 2639-2646 Published online on: 01 October 2013

Antitumor effect of 1, 8-cineole against colon cancer

Soichiro Murata, Risa Shiragami, Chihiro Kosugi, Tohru Tezuka, Masato Yamazaki, Atsushi Hirano, Yukino Yoshimura, Masato Suzuki, Kiyohiko Shuto, Nobuhiro Ohkohchi, Keiji Koda

Pages: 2647-2652 Published online on: 01 October 2013

Effect of ascorbic acid and X-irradiation on HL-60 human leukemia cells: The kinetics of reactive oxygen species

Shingo Terashima, Yoichiro Hosokawa, Hironori Yoshino, Masaru Yamaguchi, Toshiya Nakamura

Pages: 2653-2658 Published online on: 01 October 2013

Antitumor effects of telomerase-specific replication-selective oncolytic viruses for adenoid cystic carcinoma cell lines

Daisuke Sato, Yuji Kurihara, Seiji Kondo, Tatsuo Shirota, Yasuo Urata, Toshiyoshi Fujiwara, Satoru Shintani

Pages: 2659-2664 Published online on: 19 September 2013

Root bark extracts of Juncus effusus and Paeonia suffruticosa protect salivary gland acinar cells from apoptotic cell death induced by cis-platinum (II) diammine dichloride

Yoshiki Mukudai, Seiji Kondo, Sunao Shiogama, Tomoyuki Koyama, Chunnan Li, Kazunaga Yazawa, Satoru Shintani

Pages: 2665-2671 Published online on: 20 September 2013

Protein expression and subcellular localization of familial acute myelogenous leukemia-related factor

Yuanmao Huang, Lulu Chen, Meiling Ye, Shenglong Lin, Youmei Zi, Shaoyuan Wang

Pages: 2672-2676 Published online on: 01 October 2013

The BH3 mimetic S1 induces endoplasmic reticulum stress-associated apoptosis in cisplatin-resistant human ovarian cancer cells although it activates autophagy

Ning Liu, Ye Xu, Ji-Tong Sun, Jing Su, Xi-Yan Xiang, Hao-Wei Yi, Zhi-Chao Zhang, Lian-Kun Sun

Pages: 2677-2684 Published online on: 01 October 2013

Silencing of RegIV by shRNA causes the loss of stemness properties of cancer stem cells in MKN45 gastric cancer cells

Wei Zhou, Mao Sun, Dong-Lin Wang, Ying Wang, Fu Jin, Yun-Yun Zhang, Li Yang, Xiao-Ling Wu, Yong-Zhong Wu

Pages: 2685-2690 Published online on: 20 September 2013

Mechanism of the inhibition of the STAT3 signaling pathway by EGCG

Yang Wang, Xuequn Ren, Chaoyang Deng, Lu Yang, Erfu Yan, Tao Guo, Yanmin Li, Marvin Xuejun Xu

Pages: 2691-2696 Published online on: 20 September 2013

Prognostic implications of node metastatic features in OSCC: a retrospective study on 121 neck dissections

Maria Contaldo, Antonio Di Napoli, Giuseppe Pannone, Renato Franco, Franco Ionna, Antonia Feola, Alfredo De Rosa, Angela Santoro, Carolina Sbordone, Francesco Longo, Daniela Pasquali, Carla Loreto, Filippo Ricciardiello, Gennaro Esposito, Luigi D'Angelo, Angelo Itro, Pantaleo Bufo, Vincenzo Tombolini, Rosario Serpico, Marina Di Domenico

Pages: 2697-2704 Published online on: 02 October 2013

Effects of rosiglitazone on the growth and lymphangiogenesis of human gastric cancer transplanted in nude mice

Fang-Zhi Chen, Xi-Ming Mo, Qing-Ping Wang, Jun Li, Li Zhang

Pages: 2705-2712 Published online on: 28 August 2013

Anti-apoptotic effect of clusterin on cisplatin-induced cell death of retinoblastoma cells

Hyun Beom Song, Hyoung-Oh Jun, Jin Hyoung Kim, Young Suk Yu, Kyu-Won Kim, Bon Hong Min, Jeong Hun Kim

Pages: 2713-2718 Published online on: 01 October 2013

Mature BDNF promotes the growth of glioma cells in vitro

Jing Xiong, Li Zhou, Yoon Lim, Miao Yang, Yu-Hong Zhu, Zhi-Wei Li, Fiona H. Zhou, Zhi-Cheng Xiao, Xin-Fu Zhou

Pages: 2719-2724 Published online on: 20 September 2013

CD14 regulates gastric cancer cell epithelial‑mesenchymal transition and invasion in vitro

Kang Li, Zeng Dan, Xuejun Hu, Luobu Gesang, Yongge Ze, Zhaxi Bianba

Pages: 2725-2732 Published online on: 19 September 2013

Identification of CD90 as a marker for lung cancer stem cells in A549 and H446 cell lines

Xiuping Yan, Hu Luo, Xiangdong Zhou, Bingjing Zhu, Yuliang Wang, Xiuwu Bian

Pages: 2733-2740 Published online on: 03 October 2013

DcR3 regulates the growth and metastatic potential of SW480 colon cancer cells

Wei Yu, Ying-Chen Xu, Ying Tao, Ping He, Yang Li, Tao Wu, Yan-Pei Zhu, Jing Li, Ji-Xiang Wu, Jie Dai

Pages: 2741-2748 Published online on: 01 October 2013

Interleukin-24 inhibits cell migration and invasion in the neuroblastoma cell line SH-SY5Y

Baobiao Zhuo, Rong Wang, Hongwei Zhang, Haihui Qin, Yiyu Yin, Yingchun Shi

Pages: 2749-2754 Published online on: 30 September 2013

Expression of estrogen receptor α and β in esophageal squamous cell carcinoma

Jing Dong, Shi-Wen Jiang, Yanru Niu, Ling Chen, Shuyan Liu, Tianzhong Ma, Xiancai Chen, Liyan Xu, Zhongjing Su, Haibin Chen

Pages: 2771-2776 Published online on: 01 October 2013

Combination of the FGFR4 inhibitor PD173074 and 5-fluorouracil reduces proliferation and promotes apoptosis in gastric cancer

Yan-Wei Ye, Shuang Hu, Ying-Qiang Shi, Xie-Fu Zhang, Ye Zhou, Chun-Lin Zhao, Guo-Jun Wang, Jian-Guo Wen, Hong Zong

Pages: 2777-2784 Published online on: 11 October 2013

PML overexpression inhibits proliferation and promotes the osteogenic differentiation of human mesenchymal stem cells

Jie Sun, Shan Fu, Weijun Zhong, He Huang

Pages: 2785-2794 Published online on: 03 October 2013

Correlation and prognostic value of osteopontin and Bcl-2 in hepatocellular carcinoma patients after curative resection

Biao Deng, Xiao-Fei Zhang, Xu-Chao Zhu, Hua Huang, Hu-Liang Jia, Qing-Hai Ye, Qiong-Zhu Dong, Lun-Xiu Qin

Pages: 2795-2803 Published online on: 19 September 2013

Apoptotic markers in a prostate cancer cell line: Effect of ellagic acid

Luca Vanella, Claudia Di Giacomo, Rosaria Acquaviva, Ignazio Barbagallo, Venera Cardile, Dong Hyun Kim, Nader G. Abraham, Valeria Sorrenti

Pages: 2804-2810 Published online on: 30 September 2013

Associations of TP53 mutations, codon 72 polymorphism and human papillomavirus in head and neck squamous cell carcinoma patients

Qi Shi, Kang Xiao, Wei Wei, Bao-Yun Zhang, Cao Chen, Yin Xu, Li-Na Chen, Yun-Tao Song, Xiao Ma, Nai-Song Zhang, Xiao-Ping Dong

Pages: 2811-2819 Published online on: 20 September 2013

Resveratrol suppresses the STAT3 signaling pathway and inhibits proliferation of high glucose-exposed HepG2 cells partly through SIRT1

Yongguang Li, Wei Zhu, Jingbo Li, Mingya Liu, Meng Wei

Pages: 2820-2828 Published online on: 20 September 2013

Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model

Yu-Syuan Chen, Wei-Li Huang, Shu-Hao Chang, Kuo-Wei Chang, Shou-Yen Kao, Jeng-Fan Lo, Pei-Fen Su

Pages: 2829-2837 Published online on: 01 October 2013

Clinical significance of stanniocalcin 2 expression as a predictor of tumor progression in gastric cancer

Takaaki Arigami, Yoshikazu Uenosono, Sumiya Ishigami, Shigehiro Yanagita, Takahiko Hagihara, Naoto Haraguchi, Daisuke Matsushita, Tetsushi Hirahara, Hiroshi Okumura, Yasuto Uchikado, Akihiro Nakajo, Shuichi Hokita, Shoji Natsugoe

Pages: 2838-2844 Published online on: 01 October 2013

Protein-bound polysaccharide-K augments the anticancer effect of fluoropyrimidine derivatives possibly by lowering dihydropyrimidine dehydrogenase expression in gastrointestinal cancers

Eiji Mekata, Satoshi Murata, Hiromichi Sonoda, Tomoharu Shimizu, Tomoko Umeda, Hisanori Shiomi, Shigeyuki Naka, Hiroshi Yamamoto, Hajime Abe, Takeo Edamatsu, Ayako Fujieda, Masaki Fujioka, Tsutomu Wada, Tohru Tani

Pages: 2845-2851 Published online on: 04 October 2013

Regulation of ASIC1 by Ca2+/calmodulin-dependent protein kinase II in human glioblastoma multiforme

Xu Sun, Dan Zhao, Yong-Li Li, Ying Sun, Xu-Hui Lei, Jia-Ning Zhang, Ming-Ming Wu, Rui-Yan Li, Zhe-Feng Zhao, Zhi-Ren Zhang, Chuan-Lu Jiang

Pages: 2852-2858 Published online on: 02 October 2013

ETV1 induces epithelial to mesenchymal transition in human gastric cancer cells through the upregulation of Snail expression

Zhiwei Li, Libin Zhang, Zhigang Ma, Ming Yang, Jiebing Tang, Yujiao Fu, Yinling Mao, Xuan Hong, Yanqiao Zhang

Pages: 2859-2863 Published online on: 02 October 2013

Co-expression of Rho guanine nucleotide exchange factor 5 and Src associates with poor prognosis of patients with resected non-small cell lung cancer

Ping He, Wei Wu, Haidong Wang, Kelong Liao, Wei Zhang, Gang Xiong, Feng Wu, Gang Meng, Kang Yang

Pages: 2864-2870 Published online on: 14 October 2013

Lentivirus-mediated inhibition of USP39 suppresses the growth of breast cancer cells in vitro

Haibo Wang, Xiaojun Ji, Xiangping Liu, Ruyong Yao, Jingwei Chi, Shihai Liu, Yu Wang, Weihong Cao, Quan Zhou

Pages: 2871-2877 Published online on: 14 October 2013

Promoter hypermethylation of the tumor-suppressor genes RASSF1A, GSTP1 and CDH1 in endometrial cancer

Roman Fiolka, Pavol Zubor, Veronika Janusicova, Jozef Visnovsky, Andrea Mendelova, Karol Kajo, Zora Lasabova, Lukas Plank, Jan Danko

Pages: 2878-2886 Published online on: 25 September 2013

Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness

Federica Ruffini, Lucio Tentori, Annalisa Susanna Dorio, Diego Arcelli, Giulia D'Amati, Stefania D'Atri, Grazia Graziani, Pedro Miguel Lacal

Pages: 2887-2896 Published online on: 10 October 2013

miR-205 promotes the growth, metastasis and chemoresistance of NSCLC cells by targeting PTEN

Lin Lei, Yaping Huang, Wenrong Gong

Pages: 2897-2902 Published online on: 30 September 2013

Significance of INHBA expression in human colorectal cancer

Miho Okano, Hirofumi Yamamoto, Hisataka Ohkuma, Yoshihiro Kano, Hirotoshi Kim, Shimpei Nishikawa, Masamitsu Konno, Koichi Kawamoto, Naotsugu Haraguchi, Ichiro Takemasa, Tsunekazu Mizushima, Masataka Ikeda, Takehiko Yokobori, Koshi Mimori, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori, Hideshi Ishii

Pages: 2903-2908 Published online on: 01 October 2013

Molecular and clinical characteristics of MSH6 germline variants detected in colorectal cancer patients

Hiroko Terui, Tetsuhiko Tachikawa, Miho Kakuta, Yoji Nishimura, Toshimasa Yatsuoka, Kensei Yamaguchi, Kei Yura, Kiwamu Akagi

Pages: 2909-2916 Published online on: 02 October 2013

Epidermal growth factor enhances androgen receptor‑mediated bladder cancer progression and invasion via potentiation of AR transactivation

Teng-Fu Hsieh, Chi-Cheng Chen, Wen-Lung Ma, Wei-Min Chuang, Xiao-Fan Hung, Yi‑Ru Tsai, Meng-Hsueh Amanda Lin, Qiaoxia Zhang, Caixia Zhang, Chawnshang Chang, Chih-Rong Shyr

Pages: 2917-2922 Published online on: 10 October 2013

Caudatin inhibits human hepatoma cell growth and metastasis through modulation of the Wnt/β-catenin pathway

Yi Luo, Zhiguang Sun, Youbin Li, Lina Liu, Xueting Cai, Zhenlin Li

Pages: 2923-2928 Published online on: 20 September 2013

Aberrant O-GlcNAc-modified proteins expressed in primary colorectal cancer

Thanong Phueaouan, Parunya Chaiyawat, Pukkavadee Netsirisawan, Daranee Chokchaichamnankit, Phaibul Punyarit, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai

Pages: 2929-2936 Published online on: 11 October 2013

Overcoming paclitaxel resistance in uterine endometrial cancer using a COX-2 inhibitor

Kiyoshi Hasegawa, Kunimi Ishikawa, Satoshi Kawai, Yutaka Torii, Kyoko Kawamura, Rina Kato, Kazuhiko Tsukada, Yasuhiro Udagawa

Pages: 2937-2944 Published online on: 08 October 2013

In-depth bioinformatic analysis of lung cancer‑associated microRNA targets

Haiyang Zhang, Hao Yang, Rui Zhang, Chenyu Zhang, Junfeng Zhang, Donghai Li

Pages: 2945-2956 Published online on: 01 October 2013

Hypoxia-induced overexpression of DEC1 is regulated by HIF-1α in hepatocellular carcinoma

Wanshan Ma, Xiaohong Shi, Sumei Lu, Linlin Wu, Yunshan Wang

Pages: 2957-2962 Published online on: 01 October 2013

Tumor necrosis factor receptor associated factor-4: An adapter protein overexpressed in metastatic prostate cancer is regulated by microRNA-29a

Fozia Ahmed, Takumi Shiraishi, Robert L. Vessella, Prakash Kulkarni

Pages: 2963-2968 Published online on: 08 October 2013

Epigallocatechin-3-gallate and trichostatin A synergistically inhibit human lymphoma cell proliferation through epigenetic modification of p16INK4a

Dan-Sen Wu, Jian-Zhen Shen, Ai-Fang Yu, Hai-Ying Fu, Hua-Rong Zhou, Song-Fei Shen

Pages: 2969-2975 Published online on: 19 September 2013

14-3-3β regulates the proliferation of glioma cells through the GSK3β/β-catenin signaling pathway

Fanghe Gong, Guoliang Wang, Jing Ye, Tiandong Li, Hongmin Bai, Weimin Wang

Pages: 2976-2982 Published online on: 19 September 2013

Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells

Xiaoming Zhai, Yang Yang, Jianmei Wan, Ran Zhu, Yiwei Wu

Pages: 2983-2991 Published online on: 19 September 2013

Conversion chemotherapy followed by hepatic resection in colorectal cancer with initially unresectable liver-limited metastases

Gennaro Galizia, Ferdinando De Vita, Eva Lieto, Anna Zamboli, Floriana Morgillo, Paolo Castellano, Andrea Mabilia, Annamaria Auricchio, Andrea Renda, Fortunato Ciardiello, Michele Orditura

Pages: 2992-2998 Published online on: 11 October 2013

Valproic acid inhibits the growth of HeLa cervical cancer cells via caspase-dependent apoptosis

Bo Ram Han, Bo Ra You, Woo Hyun Park

Pages: 2999-3005 Published online on: 20 September 2013

Prognostic value of mitochondrial DNA content and G10398A polymorphism in non-small cell lung cancer

Hui Xu, Wei He, Huan-Gang Jiang, Hong Zhao, Xiao-Hong Peng, Yue-Hua Wei, Jing-Ni Wei, Cong-Hua Xie, Chen Liang, Ya-Hua Zhong, Gong Zhang, Di Deng, Yun-Feng Zhou, Fu-Xiang Zhou

Pages: 3006-3012 Published online on: 03 October 2013

Functional promoter polymorphisms of NFKB1 influence susceptibility to the diffuse type of gastric cancer

Tomiyasu Arisawa, Tomomitsu Tahara, Hisakazu Shiroeda, Kaho Yamada, Tomoe Nomura, Hideto Yamada, Ranji Hayashi, Kazuhiro Matsunaga, Toshimi Otsuka, Masakatsu Nakamura, Takeo Shimasaki, Nobuyuki Toshikuni, Natsuko Kawada, Tomoyuki Shibata

Pages: 3013-3019 Published online on: 01 October 2013

HSP70 and modified HPV 16 E7 fusion gene without the addition of a signal peptide gene sequence as a candidate therapeutic tumor vaccine

Jinbao Zong, Changyuan Wang, Qingyong Wang, Qinglin Peng, Yufei Xu, Xixiu Xie, Xuemei Xu

Pages: 3020-3026 Published online on: 20 September 2013

Activation of estrogen receptors with E2 downregulates peroxisome proliferator-activated receptor γ in hepatocellular carcinoma

Yueh-Min Lin, Bharath Kumar Velmurugan, Yu-Lan Yeh, Chuan  Chou Tu, Tsung-Jung Ho, Tung  Yuan Lai, Chih-Hao  Tsai, Fuu  Jen Tsai, Chang-Hai Tsai, Chih-Yang Huang

Pages: 3027-3031 Published online on: 10 October 2013

IQGAP1 plays an important role in the cell proliferation of multiple myeloma via the MAP kinase (ERK) pathway

Yongyong Ma, Zhouxiang Jin, Jin Huang, Shujuan Zhou, Haige Ye, Songfu Jiang, Kang Yu

Pages: 3032-3038 Published online on: 03 October 2013
Journal Cover

December 2013
Volume 30 Issue 6

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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