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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2013 Volume 30 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Radical trachelectomy: The first step of fertility preservation in young women with cervical cancer (Review)

Salvatore Gizzo, Emanuele Ancona, Carlo Saccardi, Tito Silvio Patrelli, Roberto Berretta, Omar Anis, Marco Noventa, Anna Bertocco, Simone Fagherazzi, Michela Longone, Lucia Vendemiati, Donato D'Antona, Giovanni Battista Nardelli
Pages: 2545-2554
Published online on: 19 September 2013

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Review

The distinct mechanisms of the antitumor activity of emodin in different types of cancer (Review)

Wei-Tian Wei, Sheng-Zhang Lin, Dian-Lei Liu, Zhao-Hong Wang
Pages: 2555-2562
Published online on: 19 September 2013

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Review

The function of human epidermal growth factor receptor-3 and its role in tumors (Review)

Qin Li, Zhenyan Yuan, Bangwei Cao
Pages: 2563-2570
Published online on: 30 September 2013

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Review

FTY720 for cancer therapy (Review)

Li Zhang, Han-Dong Wang, Xiang-Jun Ji, Zi-Xiang Cong, Jian-Hong Zhu, Yuan Zhou
Pages: 2571-2578
Published online on: 01 October 2013

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Article Open Access

Hyperexpression of HOXC13, located in the 12q13 chromosomal region, in well‑differentiated and dedifferentiated human liposarcomas

Monica Cantile, Francesca Galletta, Renato Franco, Gabriella Aquino, Giosuè Scognamiglio, Laura Marra, Margherita Cerrone, Gabriella Malzone, Angela Manna, Gaetano Apice, Flavio Fazioli, Gerardo Botti, Annarosaria De Chiara
Pages: 2579-2586
Published online on: 01 October 2013

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Article Open Access

Cryptic FUS-ERG fusion identified by RNA-sequencing in childhood acute myeloid leukemia

Ioannis Panagopoulos, Ludmila Gorunova, Bernward Zeller, Anne Tierens, Sverre Heim
Pages: 2587-2592
Published online on: 25 September 2013

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Article Open Access

The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis induction

Lenka Sucha, Milos Hroch, Martina Rezacova, Emil Rudolf, Radim Havelek, Ludek Sispera, Jana Cmielova, Renata Kohlerova, Ales Bezrouk, Pavel Tomsik
Pages: 2593-2602
Published online on: 02 October 2013

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Article Open Access

Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model

Akira Noguchi, Keiji Kikuchi, Takashi Ohtsu, Mitsuyo Yoshiwara, Yoshiyasu Nakamura, Yohei Miyagi, Huachuan Zheng, Yasuo Takano
Pages: 2603-2608
Published online on: 02 October 2013

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Article Open Access

New molecular staging with G-factors (VEGF-C and Reg IV) by supplementing TNM classification in colorectal cancers

Tetsuji Sawada, Masakazu Yashiro, Kazuhiro Sentani, Naohide Oue, Wataru Yasui, Kohji Miyazaki, Keita Kai, Hideto Fujita, Keishi Nakamura, Kiyoshi Maeda, Yoshihiro Kakeji, Shoji Natsugoe, Ken Shirabe, Sachiyo Nomura, Yutaka Shimada, Naohiro Tomita, Kosei Hirakawa, Yoshihiko Maehara
Pages: 2609-2616
Published online on: 03 October 2013

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Article Open Access

Differential telomerase expression in idiopathic pulmonary fibrosis and non-small cell lung cancer

K. M. Antoniou, K. D. Samara, I. Lasithiotaki, G. A. Margaritopoulos, G. Soufla, I. Lambiri, I. Giannarakis, I. Drositis, D. A. Spandidos, N. M. Siafakas
Pages: 2617-2624
Published online on: 25 September 2013

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Article Open Access

REG Iα gene expression is linked with the poor prognosis of lung adenocarcinoma and squamous cell carcinoma patients via discrete mechanisms

Michitaka Kimura, Hiroshi Naito, Takashi Tojo, Asako Itaya-Hironaka, Yoshiko Dohi, Mamiko Yoshimura, Kan-Ichi Nakagawara, Shin Takasawa, Shigeki Taniguchi
Pages: 2625-2631
Published online on: 19 September 2013

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Article Open Access

Gender-dependent effects of gonadectomy on lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female and male A/J mice

Fumiko Ninomiya, Masanao Yokohira, Sosuke Kishi, Yuko Nakano, Keiko Yamakawa, Tatsushi Inoue, Toshiya Kuno, Katsumi Imaida
Pages: 2632-2638
Published online on: 01 October 2013

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Article

Sarcoglycans and integrins in bisphosphonate treatment: Immunohistochemical and scanning electron microscopy study

Francesco Saverio De Ponte, Angelo Favaloro, Enrico Nastro Siniscalchi, Antonio Centofanti, Michele Runci, Giuseppina Cutroneo, Luciano Catalfamo
Pages: 2639-2646
Published online on: 01 October 2013

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Article

Antitumor effect of 1, 8-cineole against colon cancer

Soichiro Murata, Risa Shiragami, Chihiro Kosugi, Tohru Tezuka, Masato Yamazaki, Atsushi Hirano, Yukino Yoshimura, Masato Suzuki, Kiyohiko Shuto, Nobuhiro Ohkohchi, Keiji Koda
Pages: 2647-2652
Published online on: 01 October 2013

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Article

Effect of ascorbic acid and X-irradiation on HL-60 human leukemia cells: The kinetics of reactive oxygen species

Shingo Terashima, Yoichiro Hosokawa, Hironori Yoshino, Masaru Yamaguchi, Toshiya Nakamura
Pages: 2653-2658
Published online on: 01 October 2013

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Article

Antitumor effects of telomerase-specific replication-selective oncolytic viruses for adenoid cystic carcinoma cell lines

Daisuke Sato, Yuji Kurihara, Seiji Kondo, Tatsuo Shirota, Yasuo Urata, Toshiyoshi Fujiwara, Satoru Shintani
Pages: 2659-2664
Published online on: 19 September 2013

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Article

Root bark extracts of Juncus effusus and Paeonia suffruticosa protect salivary gland acinar cells from apoptotic cell death induced by cis-platinum (II) diammine dichloride

Yoshiki Mukudai, Seiji Kondo, Sunao Shiogama, Tomoyuki Koyama, Chunnan Li, Kazunaga Yazawa, Satoru Shintani
Pages: 2665-2671
Published online on: 20 September 2013

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Article

Protein expression and subcellular localization of familial acute myelogenous leukemia-related factor

Yuanmao Huang, Lulu Chen, Meiling Ye, Shenglong Lin, Youmei Zi, Shaoyuan Wang
Pages: 2672-2676
Published online on: 01 October 2013

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Article

The BH3 mimetic S1 induces endoplasmic reticulum stress-associated apoptosis in cisplatin-resistant human ovarian cancer cells although it activates autophagy

Ning Liu, Ye Xu, Ji-Tong Sun, Jing Su, Xi-Yan Xiang, Hao-Wei Yi, Zhi-Chao Zhang, Lian-Kun Sun
Pages: 2677-2684
Published online on: 01 October 2013

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Article

Silencing of RegIV by shRNA causes the loss of stemness properties of cancer stem cells in MKN45 gastric cancer cells

Wei Zhou, Mao Sun, Dong-Lin Wang, Ying Wang, Fu Jin, Yun-Yun Zhang, Li Yang, Xiao-Ling Wu, Yong-Zhong Wu
Pages: 2685-2690
Published online on: 20 September 2013

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Article

Mechanism of the inhibition of the STAT3 signaling pathway by EGCG

Yang Wang, Xuequn Ren, Chaoyang Deng, Lu Yang, Erfu Yan, Tao Guo, Yanmin Li, Marvin Xuejun Xu
Pages: 2691-2696
Published online on: 20 September 2013

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Article

Prognostic implications of node metastatic features in OSCC: a retrospective study on 121 neck dissections

Maria Contaldo, Antonio Di Napoli, Giuseppe Pannone, Renato Franco, Franco Ionna, Antonia Feola, Alfredo De Rosa, Angela Santoro, Carolina Sbordone, Francesco Longo, Daniela Pasquali, Carla Loreto, Filippo Ricciardiello, Gennaro Esposito, Luigi D'Angelo, Angelo Itro, Pantaleo Bufo, Vincenzo Tombolini, Rosario Serpico, Marina Di Domenico
Pages: 2697-2704
Published online on: 02 October 2013

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Article

Effects of rosiglitazone on the growth and lymphangiogenesis of human gastric cancer transplanted in nude mice

Fang-Zhi Chen, Xi-Ming Mo, Qing-Ping Wang, Jun Li, Li Zhang
Pages: 2705-2712
Published online on: 28 August 2013

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Article

Anti-apoptotic effect of clusterin on cisplatin-induced cell death of retinoblastoma cells

Hyun Beom Song, Hyoung-Oh Jun, Jin Hyoung Kim, Young Suk Yu, Kyu-Won Kim, Bon Hong Min, Jeong Hun Kim
Pages: 2713-2718
Published online on: 01 October 2013

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Article

Mature BDNF promotes the growth of glioma cells in vitro

Jing Xiong, Li Zhou, Yoon Lim, Miao Yang, Yu-Hong Zhu, Zhi-Wei Li, Fiona H. Zhou, Zhi-Cheng Xiao, Xin-Fu Zhou
Pages: 2719-2724
Published online on: 20 September 2013

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Article

CD14 regulates gastric cancer cell epithelial‑mesenchymal transition and invasion in vitro

Kang Li, Zeng Dan, Xuejun Hu, Luobu Gesang, Yongge Ze, Zhaxi Bianba
Pages: 2725-2732
Published online on: 19 September 2013

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Article

Identification of CD90 as a marker for lung cancer stem cells in A549 and H446 cell lines

Xiuping Yan, Hu Luo, Xiangdong Zhou, Bingjing Zhu, Yuliang Wang, Xiuwu Bian
Pages: 2733-2740
Published online on: 03 October 2013

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Article

DcR3 regulates the growth and metastatic potential of SW480 colon cancer cells

Wei Yu, Ying-Chen Xu, Ying Tao, Ping He, Yang Li, Tao Wu, Yan-Pei Zhu, Jing Li, Ji-Xiang Wu, Jie Dai
Pages: 2741-2748
Published online on: 01 October 2013

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Article

Interleukin-24 inhibits cell migration and invasion in the neuroblastoma cell line SH-SY5Y

Baobiao Zhuo, Rong Wang, Hongwei Zhang, Haihui Qin, Yiyu Yin, Yingchun Shi
Pages: 2749-2754
Published online on: 30 September 2013

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Article

Platelet-derived growth factor BB mediates the glioma-induced migration of bone marrow-derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule-1 through the PI3K, P38 MAPK and NF-κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Pages: 2755-2764
Published online on: 02 October 2013

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Article

Etoposide induces apoptosis via the mitochondrial- and caspase-dependent pathways and in non-cancer stem cells in Panc-1 pancreatic cancer cells

She-Hong Zhang, Qian Huang
Pages: 2765-2770
Published online on: 01 October 2013

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Article

Expression of estrogen receptor α and β in esophageal squamous cell carcinoma

Jing Dong, Shi-Wen Jiang, Yanru Niu, Ling Chen, Shuyan Liu, Tianzhong Ma, Xiancai Chen, Liyan Xu, Zhongjing Su, Haibin Chen
Pages: 2771-2776
Published online on: 01 October 2013

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Article

Combination of the FGFR4 inhibitor PD173074 and 5-fluorouracil reduces proliferation and promotes apoptosis in gastric cancer Expression of Concern in /10.3892/or.2025.9004

Yan-Wei Ye, Shuang Hu, Ying-Qiang Shi, Xie-Fu Zhang, Ye Zhou, Chun-Lin Zhao, Guo-Jun Wang, Jian-Guo Wen, Hong Zong
Pages: 2777-2784
Published online on: 11 October 2013

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Article

PML overexpression inhibits proliferation and promotes the osteogenic differentiation of human mesenchymal stem cells

Jie Sun, Shan Fu, Weijun Zhong, He Huang
Pages: 2785-2794
Published online on: 03 October 2013

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Article

Correlation and prognostic value of osteopontin and Bcl-2 in hepatocellular carcinoma patients after curative resection

Biao Deng, Xiao-Fei Zhang, Xu-Chao Zhu, Hua Huang, Hu-Liang Jia, Qing-Hai Ye, Qiong-Zhu Dong, Lun-Xiu Qin
Pages: 2795-2803
Published online on: 19 September 2013

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Article

Apoptotic markers in a prostate cancer cell line: Effect of ellagic acid

Luca Vanella, Claudia Di Giacomo, Rosaria Acquaviva, Ignazio Barbagallo, Venera Cardile, Dong Hyun Kim, Nader G. Abraham, Valeria Sorrenti
Pages: 2804-2810
Published online on: 30 September 2013

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Article

Associations of TP53 mutations, codon 72 polymorphism and human papillomavirus in head and neck squamous cell carcinoma patients

Qi Shi, Kang Xiao, Wei Wei, Bao-Yun Zhang, Cao Chen, Yin Xu, Li-Na Chen, Yun-Tao Song, Xiao Ma, Nai-Song Zhang, Xiao-Ping Dong
Pages: 2811-2819
Published online on: 20 September 2013

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Article

Resveratrol suppresses the STAT3 signaling pathway and inhibits proliferation of high glucose-exposed HepG2 cells partly through SIRT1

Yongguang Li, Wei Zhu, Jingbo Li, Mingya Liu, Meng Wei
Pages: 2820-2828
Published online on: 20 September 2013

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Article

Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model

Yu-Syuan Chen, Wei-Li Huang, Shu-Hao Chang, Kuo-Wei Chang, Shou-Yen Kao, Jeng-Fan Lo, Pei-Fen Su
Pages: 2829-2837
Published online on: 01 October 2013

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Article

Clinical significance of stanniocalcin 2 expression as a predictor of tumor progression in gastric cancer

Takaaki Arigami, Yoshikazu Uenosono, Sumiya Ishigami, Shigehiro Yanagita, Takahiko Hagihara, Naoto Haraguchi, Daisuke Matsushita, Tetsushi Hirahara, Hiroshi Okumura, Yasuto Uchikado, Akihiro Nakajo, Shuichi Hokita, Shoji Natsugoe
Pages: 2838-2844
Published online on: 01 October 2013

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Article

Protein-bound polysaccharide-K augments the anticancer effect of fluoropyrimidine derivatives possibly by lowering dihydropyrimidine dehydrogenase expression in gastrointestinal cancers

Eiji Mekata, Satoshi Murata, Hiromichi Sonoda, Tomoharu Shimizu, Tomoko Umeda, Hisanori Shiomi, Shigeyuki Naka, Hiroshi Yamamoto, Hajime Abe, Takeo Edamatsu, Ayako Fujieda, Masaki Fujioka, Tsutomu Wada, Tohru Tani
Pages: 2845-2851
Published online on: 04 October 2013

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Article

Regulation of ASIC1 by Ca2+/calmodulin-dependent protein kinase II in human glioblastoma multiforme

Xu Sun, Dan Zhao, Yong-Li Li, Ying Sun, Xu-Hui Lei, Jia-Ning Zhang, Ming-Ming Wu, Rui-Yan Li, Zhe-Feng Zhao, Zhi-Ren Zhang, Chuan-Lu Jiang
Pages: 2852-2858
Published online on: 02 October 2013

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Article

ETV1 induces epithelial to mesenchymal transition in human gastric cancer cells through the upregulation of Snail expression

Zhiwei Li, Libin Zhang, Zhigang Ma, Ming Yang, Jiebing Tang, Yujiao Fu, Yinling Mao, Xuan Hong, Yanqiao Zhang
Pages: 2859-2863
Published online on: 02 October 2013

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Article

Co-expression of Rho guanine nucleotide exchange factor 5 and Src associates with poor prognosis of patients with resected non-small cell lung cancer

Ping He, Wei Wu, Haidong Wang, Kelong Liao, Wei Zhang, Gang Xiong, Feng Wu, Gang Meng, Kang Yang
Pages: 2864-2870
Published online on: 14 October 2013

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Article

Lentivirus-mediated inhibition of USP39 suppresses the growth of breast cancer cells in vitro

Haibo Wang, Xiaojun Ji, Xiangping Liu, Ruyong Yao, Jingwei Chi, Shihai Liu, Yu Wang, Weihong Cao, Quan Zhou
Pages: 2871-2877
Published online on: 14 October 2013

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Article

Promoter hypermethylation of the tumor-suppressor genes RASSF1A, GSTP1 and CDH1 in endometrial cancer

Roman Fiolka, Pavol Zubor, Veronika Janusicova, Jozef Visnovsky, Andrea Mendelova, Karol Kajo, Zora Lasabova, Lukas Plank, Jan Danko
Pages: 2878-2886
Published online on: 25 September 2013

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Article

Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness

Federica Ruffini, Lucio Tentori, Annalisa Susanna Dorio, Diego Arcelli, Giulia D'Amati, Stefania D'Atri, Grazia Graziani, Pedro Miguel Lacal
Pages: 2887-2896
Published online on: 10 October 2013

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Article

miR-205 promotes the growth, metastasis and chemoresistance of NSCLC cells by targeting PTEN

Lin Lei, Yaping Huang, Wenrong Gong
Pages: 2897-2902
Published online on: 30 September 2013

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Article

Significance of INHBA expression in human colorectal cancer

Miho Okano, Hirofumi Yamamoto, Hisataka Ohkuma, Yoshihiro Kano, Hirotoshi Kim, Shimpei Nishikawa, Masamitsu Konno, Koichi Kawamoto, Naotsugu Haraguchi, Ichiro Takemasa, Tsunekazu Mizushima, Masataka Ikeda, Takehiko Yokobori, Koshi Mimori, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori, Hideshi Ishii
Pages: 2903-2908
Published online on: 01 October 2013

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Article

Molecular and clinical characteristics of MSH6 germline variants detected in colorectal cancer patients

Hiroko Terui, Tetsuhiko Tachikawa, Miho Kakuta, Yoji Nishimura, Toshimasa Yatsuoka, Kensei Yamaguchi, Kei Yura, Kiwamu Akagi
Pages: 2909-2916
Published online on: 02 October 2013

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Article

Epidermal growth factor enhances androgen receptor‑mediated bladder cancer progression and invasion via potentiation of AR transactivation

Teng-Fu Hsieh, Chi-Cheng Chen, Wen-Lung Ma, Wei-Min Chuang, Xiao-Fan Hung, Yi‑Ru Tsai, Meng-Hsueh Amanda Lin, Qiaoxia Zhang, Caixia Zhang, Chawnshang Chang, Chih-Rong Shyr
Pages: 2917-2922
Published online on: 10 October 2013

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Article

Caudatin inhibits human hepatoma cell growth and metastasis through modulation of the Wnt/β-catenin pathway

Yi Luo, Zhiguang Sun, Youbin Li, Lina Liu, Xueting Cai, Zhenlin Li
Pages: 2923-2928
Published online on: 20 September 2013

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Article

Aberrant O-GlcNAc-modified proteins expressed in primary colorectal cancer

Thanong Phueaouan, Parunya Chaiyawat, Pukkavadee Netsirisawan, Daranee Chokchaichamnankit, Phaibul Punyarit, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai
Pages: 2929-2936
Published online on: 11 October 2013

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Article

Overcoming paclitaxel resistance in uterine endometrial cancer using a COX-2 inhibitor

Kiyoshi Hasegawa, Kunimi Ishikawa, Satoshi Kawai, Yutaka Torii, Kyoko Kawamura, Rina Kato, Kazuhiko Tsukada, Yasuhiro Udagawa
Pages: 2937-2944
Published online on: 08 October 2013

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Article

In-depth bioinformatic analysis of lung cancer‑associated microRNA targets

Haiyang Zhang, Hao Yang, Rui Zhang, Chenyu Zhang, Junfeng Zhang, Donghai Li
Pages: 2945-2956
Published online on: 01 October 2013

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Article

Hypoxia-induced overexpression of DEC1 is regulated by HIF-1α in hepatocellular carcinoma Retraction in /10.3892/or.2024.8850

Wanshan Ma, Xiaohong Shi, Sumei Lu, Linlin Wu, Yunshan Wang
Pages: 2957-2962
Published online on: 01 October 2013

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Article

Tumor necrosis factor receptor associated factor-4: An adapter protein overexpressed in metastatic prostate cancer is regulated by microRNA-29a

Fozia Ahmed, Takumi Shiraishi, Robert L. Vessella, Prakash Kulkarni
Pages: 2963-2968
Published online on: 08 October 2013

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Article

Epigallocatechin-3-gallate and trichostatin A synergistically inhibit human lymphoma cell proliferation through epigenetic modification of p16INK4a

Dan-Sen Wu, Jian-Zhen Shen, Ai-Fang Yu, Hai-Ying Fu, Hua-Rong Zhou, Song-Fei Shen
Pages: 2969-2975
Published online on: 19 September 2013

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Article

14-3-3β regulates the proliferation of glioma cells through the GSK3β/β-catenin signaling pathway

Fanghe Gong, Guoliang Wang, Jing Ye, Tiandong Li, Hongmin Bai, Weimin Wang
Pages: 2976-2982
Published online on: 19 September 2013

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Article

Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells

Xiaoming Zhai, Yang Yang, Jianmei Wan, Ran Zhu, Yiwei Wu
Pages: 2983-2991
Published online on: 19 September 2013

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Article

Conversion chemotherapy followed by hepatic resection in colorectal cancer with initially unresectable liver-limited metastases

Gennaro Galizia, Ferdinando De Vita, Eva Lieto, Anna Zamboli, Floriana Morgillo, Paolo Castellano, Andrea Mabilia, Annamaria Auricchio, Andrea Renda, Fortunato Ciardiello, Michele Orditura
Pages: 2992-2998
Published online on: 11 October 2013

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Article

Valproic acid inhibits the growth of HeLa cervical cancer cells via caspase-dependent apoptosis

Bo Ram Han, Bo Ra You, Woo Hyun Park
Pages: 2999-3005
Published online on: 20 September 2013

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Article

Prognostic value of mitochondrial DNA content and G10398A polymorphism in non-small cell lung cancer

Hui Xu, Wei He, Huan-Gang Jiang, Hong Zhao, Xiao-Hong Peng, Yue-Hua Wei, Jing-Ni Wei, Cong-Hua Xie, Chen Liang, Ya-Hua Zhong, Gong Zhang, Di Deng, Yun-Feng Zhou, Fu-Xiang Zhou
Pages: 3006-3012
Published online on: 03 October 2013

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Article

Functional promoter polymorphisms of NFKB1 influence susceptibility to the diffuse type of gastric cancer

Tomiyasu Arisawa, Tomomitsu Tahara, Hisakazu Shiroeda, Kaho Yamada, Tomoe Nomura, Hideto Yamada, Ranji Hayashi, Kazuhiro Matsunaga, Toshimi Otsuka, Masakatsu Nakamura, Takeo Shimasaki, Nobuyuki Toshikuni, Natsuko Kawada, Tomoyuki Shibata
Pages: 3013-3019
Published online on: 01 October 2013

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Article

HSP70 and modified HPV 16 E7 fusion gene without the addition of a signal peptide gene sequence as a candidate therapeutic tumor vaccine

Jinbao Zong, Changyuan Wang, Qingyong Wang, Qinglin Peng, Yufei Xu, Xixiu Xie, Xuemei Xu
Pages: 3020-3026
Published online on: 20 September 2013

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Article

Activation of estrogen receptors with E2 downregulates peroxisome proliferator-activated receptor γ in hepatocellular carcinoma

Yueh-Min Lin, Bharath Kumar Velmurugan, Yu-Lan Yeh, Chuan  Chou Tu, Tsung-Jung Ho, Tung  Yuan Lai, Chih-Hao  Tsai, Fuu  Jen Tsai, Chang-Hai Tsai, Chih-Yang Huang
Pages: 3027-3031
Published online on: 10 October 2013

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Article

IQGAP1 plays an important role in the cell proliferation of multiple myeloma via the MAP kinase (ERK) pathway Retraction in /10.3892/or.2025.8882

Yongyong Ma, Zhouxiang Jin, Jin Huang, Shujuan Zhou, Haige Ye, Songfu Jiang, Kang Yu
Pages: 3032-3038
Published online on: 03 October 2013

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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