|
1
|
Mall AS: Analysis of mucins: role in
laboratory diagnosis. J Clin Pathol. 61:1018–1024. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Escande F, Lemaitre L, Moniaux N, Batra
SK, Aubert JP and Buisine MP: Genomic organization of MUC4 mucin
gene. Towards the characterization of splice variants. Eur J
Biochem. 269:3637–3644. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Andrianifahanana M, Moniaux N, Schmied BM,
et al: Mucin (MUC) gene expression in human pancreatic
adenocarcinoma and chronic pancreatitis: a potential role of MUC4
as a tumor marker of diagnostic significance. Clin Cancer Res.
7:4033–4040. 2001.PubMed/NCBI
|
|
4
|
Chaturvedi P, Singh AP and Batra SK:
Structure, evolution, and biology of the MUC4 mucin. FASEB J.
22:966–981. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Moniaux N, Escande F, Batra SK, Porchet N,
Laine A and Aubert JP: Alternative splicing generates a family of
putative secreted and membrane-associated MUC4 mucins. Eur J
Biochem. 267:4536–4544. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Baruch A, Hartmann M, Zrihan-Licht S, et
al: Preferential expression of novel MUC1 tumor antigen isoforms in
human epithelial tumors and their tumor-potentiating function. Int
J Cancer. 71:741–749. 1997. View Article : Google Scholar
|
|
7
|
Baruch A, Hartmann M, Yoeli M, et al: The
breast cancer-associated MUC1 gene generates both a receptor and
its cognate binding protein. Cancer Res. 59:1552–1561.
1999.PubMed/NCBI
|
|
8
|
Zrihan-Licht S, Baruch A, Elroy-Stein O,
Keydar I and Wreschner DH: Tyrosine phosphorylation of the MUC1
breast cancer membrane proteins. Cytokine receptor-like molecules.
FEBS Lett. 356:130–136. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
|
|
10
|
Sherr CJ: Cancer cell cycles. Science.
274:1672–1677. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Lukas J, Bartkova J and Bartek J:
Convergence of mitogenic signalling cascades from diverse classes
of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled
G1 checkpoint. Mol Cell Biol. 16:6917–6925. 1996.PubMed/NCBI
|
|
12
|
Komatsu M, Jepson S, Arango ME, Carothers
Carraway CA and Carraway KL: Muc4/sialomucin complex, an
intramembrane modulator of ErbB2/HER2/Neu, potentiates primary
tumor growth and suppresses apoptosis in a xenotransplanted tumor.
Oncogene. 20:461–470. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Croce CM: Oncogenes and cancer. N Engl J
Med. 358:502–511. 2008. View Article : Google Scholar
|
|
14
|
Cantley LC: The phosphoinositide 3-kinase
pathway. Science. 296:1655–1657. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Junttila MR, Li SP and Westermarck J:
Phosphatase-mediated crosstalk between MAPK signaling pathways in
the regulation of cell survival. FASEB J. 22:954–965. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Workman HC, Sweeney C and Carraway KL III:
The membrane mucin Muc4 inhibits apoptosis induced by multiple
insults via ErbB2-dependent and ErbB2-independent mechanisms.
Cancer Res. 69:2845–2852. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Cullen PJ, Sabbagh W Jr, Graham E, et al:
A signaling mucin at the head of the Cdc42- and MAPK-dependent
filamentous growth pathway in yeast. Genes Dev. 18:1695–1708. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Komatsu M, Carraway CA, Fregien NL and
Carraway KL: Reversible disruption of cell-matrix and cell-cell
interactions by overexpression of sialomucin complex. J Biol Chem.
272:33245–33254. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Carraway KL, Ramsauer VP and Carraway CA:
Glycoprotein contributions to mammary gland and mammary tumor
structure and function: roles of adherens junctions, ErbBs and
membrane MUCs. J Cell Biochem. 96:914–926. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ramsauer VP, Pino V, Farooq A, Carothers
Carraway CA, Salas PJ and Carraway KL: Muc4-ErbB2 complex formation
and signaling in polarized CACO-2 epithelial cells indicate that
Muc4 acts as an unorthodox ligand for ErbB2. Mol Biol Cell.
17:2931–2941. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Chaturvedi P, Singh AP, Chakraborty S, et
al: MUC4 mucin interacts with and stabilizes the HER2 oncoprotein
in human pancreatic cancer cells. Cancer Res. 68:2065–2070. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Jonckheere N, Skrypek N, Merlin J, et al:
The mucin MUC4 and its membrane partner ErbB2 regulate biological
properties of human CAPAN-2 pancreatic cancer cells via different
signalling pathways. PLoS One. 7:e322322012. View Article : Google Scholar
|
|
23
|
Moasser MM: The oncogene HER2: its
signaling and transforming functions and its role in human cancer
pathogenesis. Oncogene. 26:6469–6487. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Bafna S, Kaur S and Batra SK:
Membrane-bound mucins: the mechanistic basis for alterations in the
growth and survival of cancer cells. Oncogene. 29:2893–2904. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Jepson S, Komatsu M, Haq B, et al:
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces
specific phosphorylation of ErbB2 and enhances expression of
p27(kip), but does not activate mitogen-activated kinase or protein
kinaseB/Akt pathways. Oncogene. 21:7524–7532. 2002. View Article : Google Scholar
|
|
26
|
Gesbert F, Sellers WR, Signoretti S, Loda
M and Griffin JD: BCR/ABL regulates expression of the
cyclin-dependent kinase inhibitor p27Kip1 through the
phosphatidylinositol 3-Kinase/AKT pathway. J Biol Chem.
275:39223–39230. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Horowitz JC, Lee DY, Waghray M, et al:
Activation of the pro-survival phosphatidylinositol 3-kinase/AKT
pathway by transforming growth factor-beta1 in mesenchymal cells is
mediated by p38 MAPK-dependent induction of an autocrine growth
factor. J Biol Chem. 279:1359–1367. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Davis RJ: Signal transduction by the JNK
group of MAP kinases. Cell. 103:239–252. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Fan M, Goodwin M, Vu T, Brantley-Finley C,
Gaarde WA and Chambers TC: Vinblastine-induced phosphorylation of
Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with
inactivation of the Raf-1/MEK/ERK cascade. J Biol Chem.
275:29980–29985. 2000. View Article : Google Scholar : PubMed/NCBI
|
