|
1
|
Parkin DM and Fernandez LM: Use of
statistics to assess the global burden of breast cancer. Breast J.
12:S70–S80. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wang S, Liu Q, Zhang Y, et al: Suppression
of growth, migration and invasion of highly-metastatic human breast
cancer cells by berbamine and its molecular mechanisms of action.
Mol Cancer. 8:812009. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zhai XF, Chen Z, Li B, et al: Traditional
herbal medicine in preventing recurrence after resection of small
hepatocellular carcinoma: a multicenter randomized controlled
trial. J Integr Med. 11:90–100. 2014. View Article : Google Scholar
|
|
4
|
Jin X, Ruiz Beguerie J, Sze DM and Chan
GC: Ganoderma lucidum (Reishi mushroom) for cancer treatment.
Cochrane Database Syst Rev. 6:CD0077312012.PubMed/NCBI
|
|
5
|
Lin SZ, Wei WT, Chen H, et al: Antitumor
activity of emodin against pancreatic cancer depends on its dual
role: promotion of apoptosis and suppression of angiogenesis. PLoS
One. 7:e421462012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Liu A, Sha L, Shen Y, Huang L, Tang X and
Lin S: Experimental study on anti-metastasis effect of emodin on
human pancreatic cancer. Zhongguo Zhong Yao Za Zhi. 36:3167–3171.
2011.(In Chinese).
|
|
7
|
He L, Bi JJ, Guo Q, Yu Y and Ye XF:
Effects of emodin extracted from Chinese herbs on proliferation of
non-small cell lung cancer and underlying mechanisms. Asian Pac J
Cancer Prev. 13:1505–1510. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Ko JC, Su YJ, Lin ST, Jhan JY, Ciou SC,
Cheng CM and Lin YW: Suppression of ERCC1 and Rad51 expression
through ERK1/2 inactivation is essential in emodin-mediated
cytotoxicity in human non-small cell lung cancer cells. Biochem
Pharmacol. 79:655–664. 2010. View Article : Google Scholar
|
|
9
|
Guo J, Li W, Shi H, et al: Synergistic
effects of curcumin with emodin against the proliferation and
invasion of breast cancer cells through upregulation of miR-34a.
Mol Cell Biochem. 382:103–111. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Huang Z, Chen G and Shi P: Effects of
emodin on the gene expression profiling of human breast carcinoma
cells. Cancer Detect Prev. 32:286–291. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Yu JQ, Bao W and Lei JC: Emodin regulates
apoptotic pathway in human liver cancer cells. Phytother Res.
27:251–257. 2013. View
Article : Google Scholar
|
|
12
|
Yu CX, Zhang XQ, Kang LD, et al: Emodin
induces apoptosis in human prostate cancer cell LNCaP. Asian J
Androl. 10:625–634. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Cha TL, Qiu L, Chen CT, Wen Y and Hung MC:
Emodin downregulates androgen receptor and inhibits prostate cancer
cell growth. Cancer Res. 65:2287–2295. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Xue H, Chen Y, Cai X, Zhao L, He A, Guo K
and Zheng X: The combined effect of survivin-targeted shRNA and
emodin on the proliferation and invasion of ovarian cancer cells.
Anticancer Drugs. 24:937–944. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Yaoxian W, Hui Y, Yunyan Z, Yangqin L, Xin
G and Xiaoke W: Emodin induces apoptosis of human cervical cancer
hela cells via intrinsic mitochondrial and extrinsic death receptor
pathway. Cancer Cell Int. 13:712013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Ma YS, Weng SW, Lin MW, et al: Antitumor
effects of emodin on LS1034 human colon cancer cells in vitro and
in vivo: roles of apoptotic cell death and LS1034 tumor xenografts
model. Food Chem Toxicol. 50:1271–1278. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Wang W, Sun Y, Li X, Li H, Chen Y, Tian Y,
Yi J and Wang J: Emodin potentiates the anticancer effect of
cisplatin on gallbladder cancer cells through the generation of
reactive oxygen species and the inhibition of survivin expression.
Oncol Rep. 26:1143–1148. 2011.PubMed/NCBI
|
|
18
|
Chen YY, Chiang SY, Lin JG, et al: Emodin,
aloe-emodin and rhein inhibit migration and invasion in human
tongue cancer SCC-4 cells through the inhibition of gene expression
of matrix metalloproteinase-9. Int J Oncol. 36:1113–1120.
2010.PubMed/NCBI
|
|
19
|
Lin SY, Lai WW, Ho CC, et al: Emodin
induces apoptosis of human tongue squamous cancer SCC-4 cells
through reactive oxygen species and mitochondria-dependent
pathways. Anticancer Res. 29:327–335. 2009.PubMed/NCBI
|
|
20
|
Li WY, Chan RY, Yu PH and Chan SW: Emodin
induces cytotoxic effect in human breast carcinoma MCF-7 cell
through modulating the expression of apoptosis-related genes. Pharm
Biol. 51:1175–1181. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Yan Y, Su X, Liang Y, et al: Emodin azide
methyl anthraquinone derivative triggers mitochondrial-dependent
cell apoptosis involving in caspase-8-mediated Bid cleavage. Mol
Cancer Ther. 7:1688–1697. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Bogenrieder T and Herlyn M: Axis of evil:
molecular mechanisms of cancer metastasis. Oncogene. 22:6524–6536.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Eves P, Katerinaki E, Simpson C, et al:
Melanoma invasion in reconstructed human skin is influenced by skin
cells - investigation of the role of proteolytic enzymes. Clin Exp
Metastasis. 20:685–700. 2003. View Article : Google Scholar
|
|
24
|
Ahmad A, Wang Z, Kong D, et al: FoxM1
down-regulation leads to inhibition of proliferation, migration and
invasion of breast cancer cells through the modulation of
extra-cellular matrix degrading factors. Breast Cancer Res Treat.
122:337–346. 2010. View Article : Google Scholar
|
|
25
|
Chun J and Kim YS: Platycodin D inhibits
migration, invasion, and growth of MDA-MB-231 human breast cancer
cells via suppression of EGFR-mediated Akt and MAPK pathways. Chem
Biol Interact. 205:212–221. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wang XF, Zhou QM, Du J, Zhang H, Lu YY and
Su SB: Baicalin suppresses migration, invasion and metastasis of
breast cancer via p38 signaling pathway. Anticancer Agents Med
Chem. 13:923–931. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Ghosh S, Bishayee K and Khuda-Bukhsh AR:
Oleanolic acid isolated from ethanolic extract of Phytolacca
decandra induces apoptosis in A375 skin melanoma cells: drug-DNA
interaction and signaling cascade. J Integr Med. 12:102–114. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Cragg GM and Newman DJ: Plants as a source
of anti-cancer agents. J Ethnopharmacol. 100:72–79. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Mans DR, Rocha AB and Schwartsmann G:
Anti-cancer drug discovery and development in Brazil: targeted
plant collection as a rational strategy to acquire candidate
anti-cancer compounds. Oncologist. 5:185–198. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Yamagishi T, Sahni S, Sharp DM, Arvind A,
Jansson PJ and Richardson DR: P-glycoprotein mediates drug
resistance via a novel mechanism involving lysosomal sequestration.
J Biol Chem. 288:31761–31771. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Stanley A and Akbarsha MA: Ultrastructural
changes in the Leydig cell on treatment with vincristine. Cytobios.
79:51–58. 1994.PubMed/NCBI
|
|
32
|
Francia G, Shaked Y, Hashimoto K, et al:
Low-dose metronomic oral dosing of a prodrug of gemcitabine
(LY2334737) causes antitumor effects in the absence of inhibition
of systemic vasculogenesis. Mol Cancer Ther. 1:680–689. 2012.
View Article : Google Scholar
|
|
33
|
Srinivas G, Babykutty S, Sathiadevan PP
and Srinivas P: Molecular mechanism of emodin action: transition
from laxative ingredient to an antitumor agent. Med Res Rev.
27:591–608. 2007. View Article : Google Scholar
|
|
34
|
NTP Toxicology and Carcinogenesis Studies
of EMODIN (CAS NO. 518-82-1) Feed Studies in F344/N Rats and B6C3F1
Mice. National Toxicology Program. Natl Toxicol Program Tech Rep
Ser. 493:271–278. 2001.
|
|
35
|
Price JT and Thompson EW: Mechanisms of
tumor invasion and metastasis: emerging targets for therapy. Expert
Opin Ther Targets. 6:217–233. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Huang XX, Xu DP, Wang LQ and Gao LY:
Expression of MMP-2 and MMP-9 in the tissues of breast carcinoma
and its relationship with tumor invasion and metastasis. Chin J
Clin Rehabil. 8:2190–2192. 2004.
|
|
37
|
Stamenkovic I: Extracellular matrix
remodeling: the role of matrix metalloproteinases. J Pathol.
200:448–464. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Dung TD, Feng CC, Kuo WW, et al:
Suppression of plasminogen activators and the MMP-2/-9 pathway by a
Zanthoxylum avicennae extract to inhibit the HA22T human
hepatocellular carcinoma cell migration and invasion effects in
vitro and in vivo via phosphatase 2A activation. Biosci Biotechnol
Biochem. 77:1814–1821. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Yadav L, Puri N, Rastogi V, Satpute P,
Ahmad R and Kaur G: Matrix metalloproteinases and cancer - roles in
threat and therapy. Asian Pac J Cancer Prev. 15:1085–1091. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Wang XF, Du J, Zang TL, et al: Chinese
herbal formula PC-SPESII inhibits breast cancer metastasis in vivo
and in vitro. Evid Based Complement Alternat Med.
2013:8943862013.
|
|
41
|
Yao Q, Luo JR, Chen JH, Zhang JL, Yuan SF,
Ling R and Wang L: Expression and activation of MAPK pathway
signaling molecules in human breast cancer cell lines. Xi Bao Yu
Fen Zi Mian Yi Xue Za Zhi. 20:328–330. 2004.(In Chinese).
PubMed/NCBI
|
|
42
|
Han YC, Zeng XX, Wang R, Zhao Y, Li BL and
Song M: Correlation of p38 mitogen-activated protein kinase signal
transduction pathway to uPA expression in breast cancer. Ai Zheng.
26:48–53. 2007.(In Chinese). PubMed/NCBI
|
|
43
|
Roux PP and Blenis J: ERK and p38
MAPK-activated protein kinases: a family of protein kinases with
diverse biological functions. Microbiol Mol Biol Rev. 68:320–344.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Du J, Wang XF, Zhou QM, et al: Evodiamine
induces apoptosis and inhibits metastasis in MDA-MB-231 human
breast cancer cells in vitro and in vivo. Oncol Rep. 30:685–694.
2013.PubMed/NCBI
|
|
45
|
Tan W, Lu J, Huang M, Li Y, et al:
Anti-cancer natural products isolated from Chinese medicinal herbs.
Chin Med. 6:272011. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Ueno N, Kiyokawa N and Hung M: Growth
suppression of low HER-2/neu-expressing breast cancer cell line
MDA-MB-435 by tyrosine kinase inhibitor emodin. Oncol Rep.
3:509–511. 1996.PubMed/NCBI
|
|
47
|
Shrimali D, Shanmugam MK, Kumar AP, et al:
Targeted abrogation of diverse signal transduction cascades by
emodin for the treatment of inflammatory disorders and cancer.
Cancer Lett. 341:139–149. 2013. View Article : Google Scholar : PubMed/NCBI
|
