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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2015 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Human cancer databases (Review)

Athanasia Pavlopoulou, Demetrios A. Spandidos, Ioannis Michalopoulos
Pages: 3-18
Published online on: 31 October 2014

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Article Open Access

Activation of the mTOR signaling pathway in breast cancer MCF‑7 cells by a peptide derived from Porphyra yezoensis

Su-Jin Park, Jina Ryu, In-Hye Kim, Youn-Hee Choi, Taek-Jeong Nam
Pages: 19-24
Published online on: 20 October 2014

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Article Open Access

A retrospective examination of mean relative telomere length in the Tasmanian Familial Hematological Malignancies Study

Nicholas B. Blackburn, Jac C. Charlesworth, James R. Marthick, Elizabeth M. Tegg, Katherine A. Marsden, Velandai Srikanth, John Blangero, Ray M. Lowenthal, Simon J. Foote, Joanne L. Dickinson
Pages: 25-32
Published online on: 24 October 2014

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Article Open Access

L-glutamine decreases the severity of mucositis induced by chemoradiotherapy in patients with locally advanced head and neck cancer: A double-blind, randomized, placebo-controlled trial

Takae Tsujimoto, Yoshifumi Yamamoto, Masafumi Wasa, Yukinori Takenaka, Susumu Nakahara, Tastuya Takagi, Mamiko Tsugane, Noriyuki Hayashi, Kazuhisa Maeda, Hidenori Inohara, Etsuko Uejima, Toshinori Ito
Pages: 33-39
Published online on: 23 October 2014

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Article Open Access

Nestin predicts a favorable prognosis in early ampullary adenocarcinoma and functions as a promoter of metastasis in advanced cancer

Yan-Shen Shan, Yi-Ling Chen, Ming-Derg Lai, Hui-Ping Hsu
Pages: 40-48
Published online on: 04 November 2014

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Article Open Access

Increased expression of argininosuccinate synthetase protein predicts poor prognosis in human gastric cancer

Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Yi-Pey Luo, Yi-Ling Chen
Pages: 49-57
Published online on: 20 October 2014

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Article Open Access

Angiopoietin-like protein 2 induces androgen-independent and malignant behavior in human prostate cancer cells

Ryuta Sato, Mutsushi Yamasaki, Kenichi Hirai, Takanori Matsubara, Takeo Nomura, Fuminori Sato, Hiromitsu Mimata
Pages: 58-66
Published online on: 03 November 2014

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Article Open Access

Secretion of small/microRNAs including miR-638 into extracellular spaces by sphingomyelin phosphodiesterase 3

Shiori Kubota, Mitsuru Chiba, Miki Watanabe, Maki Sakamoto, Narumi Watanabe
Pages: 67-73
Published online on: 13 November 2014

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Article

Cyclooxygenase-2 genetic variants influence intratumoral infiltration of Foxp3-positive regulatory T cells in non-small cell lung cancer

Takuro Yukawa, Katsuhiko Shimizu, Ai Maeda, Koichiro Yasuda, Shinsuke Saisho, Riki Okita, Masao Nakata
Pages: 74-80
Published online on: 22 October 2014

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Article

Overview and evaluation of the value of fine needle aspiration cytology in determining the histogenesis of liver nodules: 14 years of experience at Hannover Medical School

B. Soudah, A. Schirakowski, M. Gebel, A. Potthoff, P. Braubach, J. Schlue, T. Krech, M. E. Dämmrich, H. H. Kreipe, M. Abbas
Pages: 81-87
Published online on: 20 October 2014

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Article

Clinical significance of the FIB-4 index for non-B non-C hepatocellular carcinoma treated with surgical resection

Hiroki Nishikawa, Yukio Osaki, Hideyuki Komekado, Azusa Sakamoto, Sumio  Saito, Norihiro Nishijima, Akihiro Nasu, Akira Arimoto, Ryuichi Kita, Toru Kimura
Pages: 88-94
Published online on: 30 October 2014

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Article

Specific growth inhibition of ErbB2‑expressing human breast cancer cells by genetically modified NK‑92 cells

Hui Liu, Bo Yang, Tingting Sun, Lin Lin, Yi Hu, Muhong Deng, Junlan Yang, Tianyi Liu, Jinyu Li, Shengjie Sun, Shunchang Jiao
Pages: 95-102
Published online on: 17 October 2014

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Article

Programmed cell death 2 protein induces gastric cancer cell growth arrest at the early S phase of the cell cycle and apoptosis in a p53-dependent manner

Jian Zhang, Wei Wei, Hui-Cheng Jin, Rong-Chao Ying, A-Kao Zhu, Fang-Jie Zhang
Pages: 103-110
Published online on: 17 October 2014

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Article

Potent antitumor activity of the Ad5/11 chimeric oncolytic adenovirus combined with interleukin-24 for acute myeloid leukemia via induction of apoptosis

Xubin Wei, Li Liu, Gang Wang, Wei Li, Ke Xu, Hongyan Qi, Hong Liu, Jing Shen, Zhongjie Li, Jimin Shao
Pages: 111-118
Published online on: 22 October 2014

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Article

Downregulation of Ras GTPase‑activating protein 1 is associated with poor survival of breast invasive ductal carcinoma patients

Yang Liu, Tong Liu, Qian Sun, Ming Niu, Yang Jiang, Da Pang
Pages: 119-124
Published online on: 13 November 2014

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Article

Antitumor effect of photodynamic therapy with a novel targeted photosensitizer on cervical carcinoma

Peng-Xi Li, Jiang-Hong Mu, Hua-Lang Xiao, Dong-Hong Li
Pages: 125-132
Published online on: 07 November 2014

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Article

Ubiquitin specific protease 22 promotes cell proliferation and tumor growth of epithelial ovarian cancer through synergy with transforming growth factor β1

Mei Ji, Huirong Shi, Ya Xie, Zhao Zhao, Shunshuang Li, Cheng Chang, Xinghan Cheng, Yue Li
Pages: 133-140
Published online on: 03 November 2014

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Article

Overexpression of ZFX and its involvement in squamous cell carcinoma of the tongue

Jirong Yin, Yi Jiang, Hao  Wu, Juncheng  Wang, Shanchuang  Zhang, Hongchen Liu
Pages: 141-148
Published online on: 29 October 2014

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Article

Slug promotes hepatocellular cancer cell progression by increasing sox2 and nanog expression

Xiulan Zhao, Baocun Sun, Dan Sun, Tieju Liu, Na Che, Qiang Gu, Xueyi Dong, Rui Li, Yanrong Liu, Jing Li
Pages: 149-156
Published online on: 22 October 2014

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Article

Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells

Xiaojun Liu, Zhongxia Yang, Zhaofeng Chen, Rui Chen, Da Zhao, Yongning Zhou, Liang Qiao
Pages: 157-162
Published online on: 12 November 2014

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Article

Anti-angiogenic effect of tanshinone IIA involves inhibition of the VEGF/VEGFR2 pathway in vascular endothelial cells

Yingying Xing, Jiajie Tu, Lufeng Zheng, Le Guo, Tao Xi
Pages: 163-170
Published online on: 07 November 2014

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Article

Establishment of a Langerhans cell histiocytosis lesion cell line with dermal dendritic cell characteristics

Ichiro Murakami, Jean Gogusev, Francis Jaubert, Michiko Matsushita, Kazuhiko Hayashi, Ikuo Miura, Takehiro Tanaka, Takashi Oka, Tadashi Yoshino
Pages: 171-178
Published online on: 24 October 2014

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Article

Novel syngeneic mouse mammary carcinoma cell lines from aggressive ErbB2/Neu-overexpressing/PTEN-deficient tumors

Qingfei Wang, Hui Ding, Hai Wang, Ping Li, Baorui  Liu, Kui Zhang
Pages: 179-184
Published online on: 30 October 2014

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Article

Effect of Smad3/4 on chemotherapeutic drug sensitivity in colorectal cancer cells

Sung Ung Moon, Mi Hyun Kang, Ji Hea Sung, Jin Won Kim, Jeong Ok Lee, Yu Jung Kim, Keun Wook Lee, Soo Mee Bang, Jong Seok Lee, Jee Hyun Kim
Pages: 185-192
Published online on: 03 November 2014

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Article

A novel human interleukin-24 peptide created by computer-guided design contributes to suppression of proliferation in esophageal squamous cell carcinoma Eca-109 cells

Qunfeng Ma, Xuefeng Deng, Bangming Jin, Yao Zhang, Dan Luo, Heyu Song, Pengkun Wang, Chi Zhang, Xue Li, Yinan Shi, Yan Liu, Zhinan Chen, Ziling Wang, Hong Jiang
Pages: 193-200
Published online on: 04 November 2014

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Article

DJ-1 knockdown inhibits growth and xenograft‑induced tumor generation of human hepatocellular carcinoma cells

Shunfang Liu, Guoxian Long, Honglan Wei, Lei Shi, Zhifang Yang, Dongbo Liu, Guoqing Hu, Hong Qiu
Pages: 201-206
Published online on: 07 November 2014

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Article

Role of gap junction intercellular communication in testicular leydig cell apoptosis induced by oxaliplatin via the mitochondrial pathway

Xuhui Tong, Xi Han, Binbin Yu, Meiling Yu, Guojun Jiang, Jie Ji, Shuying Dong
Pages: 207-214
Published online on: 29 October 2014

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Article

Analysis of the amount of tissue sample necessary for mitotic count and Ki-67 index in gastrointestinal stromal tumor sampling

Hideki Kobara, Hirohito Mori, Kazi Rafiq, Shintaro Fujihara, Noriko Nishiyama, Taiga Chiyo, Tae Matsunaga, Maki Ayaki, Tatsuo Yachida, Kiyohito Kato, Hideki Kamada, Koji Fujita, Asahiro Morishita, Makoto Oryu, Kunihiko Tsutsui, Hisakazu Iwama, Yoshio Kushida, Reiji Haba, Tsutomu Masaki
Pages: 215-222
Published online on: 14 November 2014

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Article

Kazinol C from Broussonetia kazinoki activates AMP-activated protein kinase to induce antitumorigenic effects in HT-29 colon cancer cells

Hak-Su Kim, Jihyun Lim, Da Yeon Lee, Jae-Ha Ryu, Jong-Seok Lim
Pages: 223-229
Published online on: 12 November 2014

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Article

Comparative effects of SNX-7081 and SNX-2112 on cell cycle, apoptosis and Hsp90 client proteins in human cancer cells

Xiao Wang, Shaoxiang Wang, Yuting Liu, Dane Huang, Kai Zheng, Yi Zhang, Xiaoyan Wang, Qiuying Liu, Depo Yang, Yifei Wang
Pages: 230-238
Published online on: 20 October 2014

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Article

In vitro synergistic antitumor efficacy of sequentially combined chemotherapy/icotinib in non‑small cell lung cancer cell lines

Min‑Cong Wang, Xuan Liang, Zhi‑Yan Liu, Jie Cui, Ying Liu, Li Jing, Li‑Li Jiang, Jie‑Qun Ma, Li‑Li Han, Qian‑Qian Guo, Cheng‑Cheng Yang, Jing Wang, Tao Wu, Ke‑Jun Nan, Yu Yao
Pages: 239-249
Published online on: 03 November 2014

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Article

Expression of special AT-rich sequence-binding protein 1 is an independent prognostic factor in cutaneous T-cell lymphoma

Dariusz Grzanka, Maciej Gagat, Magdalena Izdebska, Andrzej Marszałek
Pages: 250-266
Published online on: 11 November 2014

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Article

Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma

Paulisally Hau Yi Lo, Chizu Tanikawa, Toyomasa Katagiri, Yusuke Nakamura, Koichi Matsuda
Pages: 267-273
Published online on: 03 November 2014

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Article

Hepatocellular carcinomas promote tumor-associated macrophage M2-polarization via increased B7-H3 expression

Fu-Biao Kang, Ling Wang, Dong Li, Yin-Ge Zhang, Dian-Xing Sun
Pages: 274-282
Published online on: 04 November 2014

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Article

Loss of function of SWI/SNF chromatin remodeling genes leads to genome instability of human lung cancer

Hai-Tao Huang, Shao-Mu Chen, Liang-Bin Pan, Jie Yao, Hai-Tao Ma
Pages: 283-291
Published online on: 03 November 2014

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Article

Vaccination with OVA-bound nanoparticles encapsulating IL-7 inhibits the growth of OVA-expressing E.G7 tumor cells in vivo

Hiroko Toyota, Noriko Yanase, Takayuki Yoshimoto, Mitsunori Harada, Yasuki Kato, Junichiro Mizuguchi
Pages: 292-296
Published online on: 12 November 2014

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Article

Molecular mechanism of epigallocatechin-3-gallate in human esophageal squamous cell carcinoma in vitro and in vivo

Lifeng Liu, Lei Hou, Shanzhi Gu, Xiaoxiao Zuo, Du Meng, Minna  Luo, Xiaojin Zhang, Shangke Huang, Xinhan Zhao
Pages: 297-303
Published online on: 20 October 2014

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Article

Chidamide, a histone deacetylase inhibitor, functions as a tumor inhibitor by modulating the ratio of Bax/Bcl-2 and P21 in pancreatic cancer

Bin Zhao, Tianlin He
Pages: 304-310
Published online on: 10 November 2014

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Article

Evaluation of melatonin treatment in primary culture of canine mammary tumors

Juliana Ramos Lopes, Larissa Bazela Maschio, Bruna Victorasso Jardim-Perassi, Marina Gobbe Moschetta, Lívia Carvalho Ferreira, Gustavo Rodrigues Martins, Gabriela Bottaro Gelaleti, Debora Aparecida Pires De Campos Zuccari
Pages: 311-319
Published online on: 11 November 2014

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Article

Overexpression of Reg4, alone or combined with MMP-7 overexpression, is predictive of poor prognosis in colorectal cancer

Xingwu Zhu, Yang Han, Chenwei Yuan, Weiwei Tu, Guoqiang Qiu, Su Lu, Huijun Lu, Zhihai Peng, Chongzhi Zhou
Pages: 320-328
Published online on: 22 October 2014

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Article

Evaluation of HAAH/humbug quantitative detection in the diagnosis of hepatocellular carcinoma

Tian Xue, Jing Su, Hongmin Li, Xiaoping Xue
Pages: 329-337
Published online on: 13 November 2014

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Article

Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo

Yang Sun, Xiufeng Wang, Qianmei Zhou, Yiyu Lu, Hui Zhang, Qilong Chen, Ming Zhao, Shibing Su
Pages: 338-346
Published online on: 03 November 2014

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Article

Evaluation of diethylnitrosamine- or hepatitis B virus X gene-induced hepatocellular carcinoma with 18F-FDG PET/CT: A preclinical study

Ju Hui Park, Joo Hyun Kang, Yong Jin Lee, Kwang Il Kim, Tae Sup Lee, Kyeong Min Kim, Ji Ae Park, Yin Ohk Ko, Dae-Yeul Yu, Sang-Soep Nahm, Tae Joo Jeon, Young-Seo Park, Sang Moo Lim
Pages: 347-353
Published online on: 30 October 2014

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Article

Functionally distinct subsets of CD4+ regulatory T cells in patients with laryngeal squamous cell carcinoma are indicative of immune deregulation and disease progression

Wei Sun, Wei-Jin Li, Qing-Ling Fu, Chang-You Wu, Ji-Zhen Lin, Xiao-Lin Zhu, Wei-Jian Hou, Yi Wei, Yi-Hui Wen, Yue-Jian Wang, Wei-Ping Wen
Pages: 354-362
Published online on: 20 October 2014

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Article

Overexpression of adenylate cyclase-associated protein 1 may predict brain metastasis in non-small cell lung cancer

Shuan-Shuan Xie, Min Tan, Hai-Yan Lin, Lei Xu, Chang-Xing Shen, Qing Yuan, Xiao-Lian Song, Chang-Hui Wang
Pages: 363-371
Published online on: 30 October 2014

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Article

Effects of VBMDMP on the reversal of cisplatin resistance in human lung cancer A549/DDP cells

Cheng-Kun Wang, Yang Zhang, Zhi-Jie Zhang, Qin-Wei Qiu, Jian-Guo Cao, Zhi-Min He
Pages: 372-382
Published online on: 13 November 2014

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Article

Establishment of human pancreatic cancer gemcitabine‑resistant cell line with ribonucleotide reductase overexpression

Congfei Wang, Weiwei Zhang, Mingjuan Fu, Aiqin Yang, Heguang Huang, Jieming Xie
Pages: 383-390
Published online on: 12 November 2014

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Article

Usefulness of plasma HGF level for monitoring acquired resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer

Hitomi Umeguchi, Naoko Sueoka-Aragane, Naomi Kobayashi, Tomomi Nakamura, Akemi Sato, Yuji Takeda, Shinichiro Hayashi, Eisaburo Sueoka, Shinya Kimura
Pages: 391-396
Published online on: 22 October 2014

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Article

Downregulation of PLZF in human hepatocellular carcinoma and its clinical significance

Anselm Wang-Hei Hui, Hon-Wai Lau, Cyanne Ye Cao, Jun-Wei Zhou, Paul Bo-San Lai, Stephen Kwok-Wing Tsui
Pages: 397-402
Published online on: 30 October 2014

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Article

Promotive role of recombinant HE4 protein in proliferation and carboplatin resistance in ovarian cancer cells

Huan Wang, Liancheng Zhu, Jian Gao, Zhenhua Hu, Bei Lin
Pages: 403-412
Published online on: 17 October 2014

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Article

Inhibition of basal JNK activity by small interfering RNAs enhances cisplatin sensitivity and decreases DNA repair in T98G glioblastoma cells

Eduardo Parra, Luis Gutiérrez, Jorge Ferreira
Pages: 413-418
Published online on: 24 October 2014

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Article

Chelidonium majus L. extract induces apoptosis through caspase activity via MAPK-independent NF-κB signaling in human epidermoid carcinoma A431 cells

Seung-Won Park, Seong Ryul Kim, Youngchul Kim, Jang-Hoon Lee, Hong-Jung Woo, Yeo-Kwang Yoon, Young Il Kim
Pages: 419-424
Published online on: 23 October 2014

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Article

Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity

Sulan Li, Dongli Yue, Xinfeng Chen, Liping Wang, Jieyao Li, Yu Ping, Qun Gao, Dan Wang, Tengfei Zhang, Feng Li, Li Yang, Lan Huang, Yi Zhang
Pages: 425-432
Published online on: 24 October 2014

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Article

Flavonoids in Ginkgo biloba fallen leaves induce apoptosis through modulation of p53 activation in melanoma cells

Hye-Jung Park, Moon-Moo Kim
Pages: 433-438
Published online on: 12 November 2014

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Article

Non-genomic actions of estradiol and 4-OH-tamoxifen on murine breast cancer cells

Diego Raffo, Osvaldo Pontiggia, Elisa Bal de Kier Joffé, Marina Simian
Pages: 439-447
Published online on: 22 October 2014

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Article

Synthetic miR-145 mimic inhibits multiple myeloma cell growth in vitro and in vivo Retraction in /10.3892/or.2021.8125

Qi Zhang, Weiqun Yan, Yang Bai, Hao Xu, Changhao Fu, Wenwen Zheng, Yingqiao Zhu, Jie Ma
Pages: 448-456
Published online on: 05 November 2014

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Article

Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1α signaling pathway

Fenglin Chen, Mingkai Zhuang, Canmei Zhong, Jun Peng, Xiaozhong Wang, Jianying Li, Zhixin Chen, Yuehong Huang
Pages: 457-463
Published online on: 17 October 2014

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In vitro cytotoxicity of 4'-OH-tamoxifen and estradiol in human endometrial adenocarcinoma cells HEC-1A and HEC-1B

Maria E. Cuevas, Tracey E. Lindeman
Pages: 464-470
Published online on: 23 October 2014

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Combination of the mTOR inhibitor RAD001 with temozolomide and radiation effectively inhibits the growth of glioblastoma cells in culture

Hélène Burckel, Elodie Josset, Jean-Marc Denis, John Gueulette, Jakobus Slabbert, Georges Noël, Pierre Bischoff
Pages: 471-477
Published online on: 04 November 2014

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Treg/Th17 imbalance in malignant pleural effusion partially predicts poor prognosis

Guangdie Yang, Hequan Li, Yinan Yao, Fei Xu, Zhang Bao, Jianying Zhou
Pages: 478-484
Published online on: 30 October 2014

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Article

Emerging role of microRNAs in modulating endothelin-1 expression in gastric cancer

Kuo-Wang Tsai, Ling-Yueh Hu, Ting-Wen Chen, Sung-Chou Li, Meng‑Ru Ho, Shou-Yu Yu, Ya-Ting Tu, Wei-Shone Chen, Hing-Chung Lam
Pages: 485-493
Published online on: 11 November 2014

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JAK2 inhibitor blocks the inflammation and growth of esophageal squamous cell carcinoma in vitro through the JAK/STAT3 pathway

Juemin Fang, Li Chu, Chunyan Li, Yijing Chen, Fei Hu, Xi Zhang, Huaxin Zhao, Zhuqing Liu, Qing Xu
Pages: 494-502
Published online on: 14 November 2014

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Journal Cover
January-2026 Volume 55 Issue 1

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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