|
1
|
Parkin DM, Bray F, Ferlay J and Pisani P:
Global cancer statistics, 2002. CA Cancer J Clin. 55:74–108. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lau WY and Lai EC: Hepatocellular
carcinoma: current management and recent advances. Hepatobiliary
Pancreat Dis Int. 7:237–257. 2008.PubMed/NCBI
|
|
3
|
Bjerkvig R, Tysnes BB, Aboody KS, et al:
Opinion: the origin of the cancer stem cell: current controversies
and new insights. Nat Rev Cancer. 5:899–904. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Visvader JE and Lindeman GJ: Cancer stem
cells in solid tumors: accumulating evidence and unresolved
questions. Nat Rev Cancer. 8:755–768. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Simeone DM: Pancreatic cancer stem cells:
implications for the treatment of pancreatic cancer. Clin Cancer
Res. 14:5646–5648. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Zhang N, Li R, Tao KS, et al:
Characterization of a stem-like population in hepatocellular
carcinoma MHCC97 cells. Oncol Rep. 23:827–831. 2010.PubMed/NCBI
|
|
7
|
Chen J, Wang J, Lin L, et al: Inhibition
of STAT3 signaling pathway by nitidine chloride suppressed the
angiogenesis and growth of human gastric cancer. Mol Cancer Ther.
11:277–287. 2012. View Article : Google Scholar
|
|
8
|
Ho PL, Lay EJ, Jian W, et al: Stat3
activation in urothelial stem cells leads to direct progression to
invasive bladder cancer. Cancer Res. 72:3135–3142. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chen B, Liu J, Chang Q, et al: JNK and
STAT3 signaling pathways converge on Akt-mediated phosphorylation
of EZH2 in bronchial epithelial cells induced by arsenic. Cell
Cycle. 12:112–121. 2013. View
Article : Google Scholar :
|
|
10
|
Cao Q, Li YY, He WF, et al: Interplay
between microRNAs and the STAT3 signaling pathway in human cancers.
Physiol Genomics. 45:1206–1214. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Iliopoulos D, Jaeger SA, Hirsch HA, et al:
STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are
part of the epigenetic switch linking inflammation to cancer. Mol
Cell. 39:493–506. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Zhou X, Ren Y, Liu A, et al: STAT3
inhibitor WP1066 attenuates miRNA-21 to suppress human oral
squamous cell carcinoma growth in vitro and in vivo. Oncol Rep.
31:2173–2180. 2014.PubMed/NCBI
|
|
13
|
Liu C, Yu J, Yu S, et al: MicroRNA-21 acts
as an oncomir through multiple targets in human hepatocellular
carcinoma. J Hepatol. 53:98–107. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wang Y, Gao X, Wei F, Zhang X, et al:
Diagnostic and prognostic value of circulating miR-21 for cancer: a
systematic review and meta-analysis. Gene. 533:389–397. 2014.
View Article : Google Scholar
|
|
15
|
Zhou L, Yang ZX, Song WJ, et al:
MicroRNA-21 regulates the migration and invasion of a stem-like
population in hepatocellular carcinoma. Int J Oncol. 43:661–669.
2013.PubMed/NCBI
|
|
16
|
Marotta LL, Almendro V, Marusyk A, et al:
The JAK2/STAT3 signaling pathway is required for growth of
CD44+CD24− stem cell-like breast cancer cells
in human tumors. J Clin Invest. 121:2723–2735. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Bourguignon LY, Earle C, Wong G, Spevak CC
and Krueger K: Stem cell marker (Nanog) and Stat-3 signaling
promote microRNA-21 expression and chemoresistance in
hyaluronan/CD44-activated head and neck squamous cell carcinoma
cells. Oncogene. 31:149–160. 2012. View Article : Google Scholar
|
|
18
|
Sawant DV, Wu H, Kaplan MH, et al: The
Bcl6 target gene microRNA-21 promotes Th2 differentiation by a T
cell intrinsic pathway. Mol Immunol. 54:435–442. 2012. View Article : Google Scholar
|
|
19
|
Haura EB, Turkson J and Jove R: Mechanisms
of disease: insights into the emerging role of signal transducers
and activators of transcription in cancer. Nat Clin Pract Oncol.
2:315–324. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Huang S: Regulation of metastases by
signal transducer and activator of transcription 3 signaling
pathway: clinical implications. Clin Cancer Res. 13:1362–1366.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Löffler D, Brocke-Heidrich K, Pfeifer G,
et al: Interleukin-6 dependent survival of multiple myeloma cells
involves the Stat3-mediated induction of microRNA-21 through a
highly conserved enhancer. Blood. 110:1330–1333. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Takahashi C, Sheng Z, Horan TP, et al:
Regulation of matrix metalloproteinase-9 and inhibition of tumor
invasion by the membrane-anchored glycoprotein RECK. Proc Natl Acad
Sci USA. 95:13221–13226. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kotzsch M, Farthmann J, Meye A, et al:
Prognostic relevance of uPAR-del4/5 and TIMP-3 mRNA expression
levels in breast cancer. Eur J Cancer. 41:2760–2768. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Takenaka K, Ishikawa S, Kawano Y, et al:
Expression of a novel matrix metalloproteinase regulator, RECK and
its clinical significance in resected non-small cell lung cancer.
Eur J Cancer. 40:1617–1623. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Allgayer H: Pdcd4, a colon cancer
prognostic that is regulated by a microRNA. Crit Rev Oncol Hematol.
73:185–191. 2010. View Article : Google Scholar
|
|
26
|
Lankat-Buttgereit B and Goke R: The tumour
suppressor Pdcd4: recent advances in the elucidation of function
and regulation. Biol Cell. 101:309–317. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Yang HS, Matthews CP, Clair T, et al:
Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated
protein kinase kinase kinase kinase 1 expression to suppress colon
carcinoma cell invasion. Mol Cell Biol. 26:1297–1306. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Wang Q, Sun Z and Yang HS: Downregulation
of tumor suppressor Pdcd4 promotes invasion and activates both
beta-catenin/Tcf and AP-1-dependent transcription in colon
carcinoma cells. Oncogene. 27:1527–1535. 2008. View Article : Google Scholar
|
|
29
|
Nieves-Alicea R, Colburn NH, Simeone AM,
et al: Programmed cell death 4 inhibits breast cancer cell invasion
by increasing tissue inhibitor of metalloproteinase-2 expression.
Breast Cancer Res Treat. 114:203–209. 2009. View Article : Google Scholar :
|
|
30
|
Rajendran P, Li F, Shanmugam MK, et al:
Celastrol suppresses growth and induces apoptosis of human
hepatocellular carcinoma through the modulation of STAT3/JAK2
signaling cascade in vitro and in vivo. Cancer Prev Res. 5:631–643.
2012. View Article : Google Scholar
|
|
31
|
Meydan N, Grunberger T, Dadi H, et al:
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor.
Nature. 13:645–648. 1996. View
Article : Google Scholar
|
