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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2015 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Mitochondrial changes in endometrial carcinoma: Possible role in tumor diagnosis and prognosis (Review)

Antonella Cormio, Gennaro Cormio, Clara Musicco, Anna Maria Sardanelli, Giuseppe Gasparre, Maria Nicola Gadaleta
Pages: 1011-1018
Published online on: 22 December 2014

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Review

Statins are potential anticancerous agents (Review)

Abdullah K. Altwairgi
Pages: 1019-1039
Published online on: 20 January 2015

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Article Open Access

A new rapid method for detecting epidermal growth factor receptor mutations in non-small cell lung cancer

Miyako Takata, Hiroki Chikumi, Keiji Matsunami, Masahiro Kodani, Tomohiro Sakamoto, Kazuhiro Hashimoto, Masaki Nakamoto, Kensaku Okada, Tsuyoshi Kitaura, Shingo Matsumoto, Jun Kurai, Akira Yamasaki, Tadashi Igishi, Naoto Burioka, Eiji Shimizu
Pages: 1040-1048
Published online on: 14 January 2015

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Article Open Access

Overexpression of interleukin-18 protein reduces viability and induces apoptosis of tongue squamous cell carcinoma cells by activation of glycogen synthase kinase-3β signaling

Weiwei Liu, Min Hu, Yumei Wang, Baozhen Sun, Yu Guo, Zhimin Xu, Jia Li, Bing Han
Pages: 1049-1056
Published online on: 15 January 2015

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Article Open Access

Salinomycin inhibits hepatocellular carcinoma cell invasion and migration through JNK/JunD pathway-mediated MMP9 expression

Ling Xu, Ting Wang, Wen-Ying Meng, Jue Wei, Jia-Li Ma, Min Shi, Yu-Gang Wang
Pages: 1057-1063
Published online on: 18 December 2014

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Article

Upregulated Annexin A1 promotes cellular invasion in triple-negative breast cancer

Maiko Okano, Kensuke Kumamoto, Motonobu Saito, Hisashi Onozawa, Katsuharu Saito, Noriko Abe, Tohru Ohtake, Seiichi Takenoshita
Pages: 1064-1070
Published online on: 14 January 2015

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Article

Clinical implication of the preoperative GSA index in 99mTc-GSA scintigraphy in hepatitis C virus-related hepatocellular carcinoma

Hiroki Nishikawa, Yukio Osaki, Hideyuki Komekado, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Akira Arimoto, Ryuichi Kita, Toru Kimura
Pages: 1071-1078
Published online on: 22 December 2014

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Article

Combined treatment of XIAP-targeting shRNA and celecoxib synergistically inhibits the tumor growth of non‑small cell lung cancer cells in vitro and in vivo

Hong Zhang, Zhihong Li, Kaizhong Wang, Ping Ren
Pages: 1079-1088
Published online on: 18 December 2014

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Article

CDK5RAP1 deficiency induces cell cycle arrest and apoptosis in human breast cancer cell line by the ROS/JNK signaling pathway

Hongbin Wang, Li Wei, Changli Li, Jing Zhou, Zhigao Li
Pages: 1089-1096
Published online on: 20 January 2015

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Article

Dickkopf‑3 (Dkk3) induces apoptosis in cisplatin‑resistant lung adenocarcinoma cells via the Wnt/β‑catenin pathway

Zheng Wang, Li‑Jun Ma, Yi Kang, Xiao Li, Xiao‑Ju Zhang
Pages: 1097-1106
Published online on: 30 December 2014

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Article

Cycloartan-24-ene-1α,2α,3β-triol, a cycloartane-type triterpenoid from the resinous exudates of Commiphora myrrha, induces apoptosis in human prostatic cancer PC-3 cells

Wenyan Gao, Xiaojie Su, Xiaoyan Dong, Yingli Chen, Chunlan Zhou, Ping Xin, Chunhao Yu, Taiming Wei
Pages: 1107-1114
Published online on: 15 January 2015

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Article

microRNA-195 functions as a tumor suppressor by inhibiting CBX4 in hepatocellular carcinoma Retraction in /10.3892/or.2021.8145

Changli Zheng, Jingjing Li, Qi Wang, Wei Liu, Jianda Zhou, Rui Liu, Qinghai Zeng, Xiaowei Peng, Chenghui Huang, Peiguo Cao, Ke Cao
Pages: 1115-1122
Published online on: 19 January 2015

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Article

Paired related homeobox 1 is associated with the invasive properties of glioblastoma cells

Mai Sugiyama, Hitoki Hasegawa, Satoko Ito, Kazuya Sugiyama, Masao Maeda, Kosuke Aoki, Toshihiko Wakabayashi, Michinari Hamaguchi, Atsushi Natsume, Takeshi Senga
Pages: 1123-1130
Published online on: 18 December 2014

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Article

Aged garlic extract inhibits 1,2-dimethylhydrazine-induced colon tumor development by suppressing cell proliferation

Hiroshi Jikihara, Guangying Qi, Koichiro Nozoe, Mayumi Hirokawa, Hiromi Sato, Yuka Sugihara, Fumio Shimamoto
Pages: 1131-1140
Published online on: 30 December 2014

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Article

Synthesized tetrahydroisoquinoline alkaloid exerts anticancer effects at least in part by suppressing NF‑κB‑regulated proteins in A549 human lung cancer cells

Won Sup Lee, Jeong Won Yun, Arulkumar Nagappan, Jing Nan Lu, Min Jeong Kim, Jeong-Hee Lee, Dong Hoon Kim, Yung Hyun Choi, Hye Jung Kim, Ki Churl Chang, Jin-Myung Jung
Pages: 1141-1146
Published online on: 08 December 2014

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Article

Silencing of the ABCC4 gene by RNA interference reverses multidrug resistance in human gastric cancer

Guangyu Zhang, Zhenran Wang, Feng Qian, Chen Zhao, Chaowen Sun
Pages: 1147-1154
Published online on: 30 December 2014

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Article

RNAi-mediated knockdown of the c-jun gene sensitizes radioresistant human nasopharyngeal carcinoma cell line CNE-2R to radiation

Si-Yan Guo, Xiao-Dong Zhu, Lian-Ying Ge, Song Qu, Ling Li, Fang Su, Ya Guo
Pages: 1155-1160
Published online on: 22 December 2014

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Article

Icotinib hydrochloride enhances the effect of radiotherapy by affecting DNA repair in colorectal cancer cells

Hong Ma, Jianping Bi, Tao Liu, Yang Ke, Sheng Zhang, Tao Zhang
Pages: 1161-1170
Published online on: 30 December 2014

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Article

Deferoxamine inhibits TRAIL-mediated apoptosis via regulation of autophagy in human colon cancer cells

Ji-Hong Moon, Jae-Kyo Jeong, Sang-Youel Park
Pages: 1171-1176
Published online on: 18 December 2014

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Article

Silencing XIAP suppresses osteosarcoma cell growth, and enhances the sensitivity of osteosarcoma cells to doxorubicin and cisplatin Retraction in /10.3892/or.2021.8213

Yang Qu, Peng Xia, Shanyong Zhang, Su Pan, Jianwu Zhao
Pages: 1177-1184
Published online on: 23 December 2014

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Article

Ubiquitin ligase Siah1 promotes the migration and invasion of human glioma cells by regulating HIF-1α signaling under hypoxia

Hengliang Shi, Bao Zheng, Yuxuan Wu, Yuan Tang, Lei Wang, Yong Gao, Hui Gong, Jin Du, Rutong Yu
Pages: 1185-1190
Published online on: 23 December 2014

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Article

(+)‑Terrein inhibits human hepatoma Bel‑7402 proliferation through cell cycle arrest

Fengli Zhang, Meiheriguli Mijiti, Wei Ding, Jiale Song, Ying Yin, Wei Sun, Zhiyong Li
Pages: 1191-1200
Published online on: 14 January 2015

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Article

Overexpression of RhoGDI2 correlates with the progression and prognosis of pancreatic carcinoma

Bin Yi, Yi Zhang, Dongming Zhu, Lifeng Zhang, Shiduo Song, Songbing He, Bing Zhang, Dechun Li, Jian Zhou
Pages: 1201-1206
Published online on: 07 January 2015

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Article

Wnt3a increases the metastatic potential of non-small cell lung cancer cells in vitro in part via its upregulation of Notch3

Chunyan Li, Gongru Song, Siyang Zhang, Enhua Wang, Zeshi Cui
Pages: 1207-1214
Published online on: 30 December 2014

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Article

miRNA‑542‑3p downregulation promotes trastuzumab resistance in breast cancer cells via AKT activation

Tao Ma, Lu Yang, Jin Zhang
Pages: 1215-1220
Published online on: 13 January 2015

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Article

MicroRNA-221 accelerates the proliferation of laryngeal cancer cell line Hep-2 by suppressing Apaf-1

Xin Sun, Bin Liu, Xu-Dong Zhao, Li-Yin Wang, Wen-Yue Ji
Pages: 1221-1226
Published online on: 13 January 2015

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Article

Stimulation of peroxisome proliferator-activated receptor γ inhibits estrogen receptor α transcriptional activity in endometrial carcinoma cells Retraction in /10.3892/or.2024.8836

Guiyu Zhang, Xinxin Hou, Shuhong Gao
Pages: 1227-1234
Published online on: 15 January 2015

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Article

Misregulation of polo-like protein kinase 1, P53 and P21WAF1 in epithelial ovarian cancer suggests poor prognosis

Ruitao Zhang, Huirong Shi, Fang Ren, Huina Liu, Minghui Zhang, Youxing Deng, Xia Li
Pages: 1235-1242
Published online on: 15 January 2015

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Article

A novel PALB2 truncating mutation in an Italian family with male breast cancer

Maria Teresa Vietri, Gemma Caliendo, Amelia Casamassimi, Michele Cioffi, Maria Laura De Paola, Claudio Napoli, Anna Maria Molinari
Pages: 1243-1247
Published online on: 22 December 2014

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Article

Multiple antigenic polypeptide composed of heparanase B‑cell epitopes shrinks human hepatocellular carcinoma in mice

Jun Zhang, Jianmin Yang, Yuan Cai, Ni Jin, Huiju Wang, Tong Yu
Pages: 1248-1256
Published online on: 18 December 2014

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Article

Sphingosine kinase 1 enhances the invasion and migration of non-small cell lung cancer cells via the AKT pathway

Liangming Zhu, Zhou Wang, Yuxia Lin, Zhitao Chen, Haibo Liu, Ying Chen, Ningning Wang, Xiue Song
Pages: 1257-1263
Published online on: 19 December 2014

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Article

Nitidine chloride induces apoptosis in human hepatocellular carcinoma cells through a pathway involving p53, p21, Bax and Bcl-2

Xianhong Ou, You Lu, Liufeng Liao, Danni Li, Limin Liu, Huagang Liu, Heng Xu
Pages: 1264-1274
Published online on: 22 December 2014

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Article

MicroRNA-10b is upregulated and has an invasive role in colorectal cancer through enhanced Rhoc expression

Yun-Feng Wang, Zhen Li, Xu-Hong Zhao, Xiao-Ming Zuo, Yong Zhang, Yi-Hua Xiao, Jian Li, Zhi-Hai Peng
Pages: 1275-1283
Published online on: 20 January 2015

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Article

Ethyl gallate suppresses proliferation and invasion in human breast cancer cells via Akt-NF-κB signaling Corrigendum in /10.3892/or.2024.8787

Hongxia Cui, Jiaxin Yuan, Xiaohui Du, Ming Wang, Liling Yue, Jicheng Liu
Pages: 1284-1290
Published online on: 18 December 2014

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Article

miR-142 acts as a tumor suppressor in osteosarcoma cell lines by targeting Rac1

Zhonghui Zheng, Muliang Ding, Jiangdong Ni, Deye Song, Jun Huang, Junjie Wang
Pages: 1291-1299
Published online on: 22 December 2014

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Article

Nucleosome-binding protein HMGN2 exhibits antitumor activity in human SaO2 and U2-OS osteosarcoma cell lines Corrigendum in /10.3892/or.2024.8827

Guojun Liang, Enjie Xu, Chaoqun Yang, Chenglin Zhang, Xiaolong Sheng, Xuhui Zhou
Pages: 1300-1306
Published online on: 22 December 2014

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Article

Combination of HSV1-TK/shTERT by retrovirus vector inhibits hepatocellular carcinoma cell growth in vitro and in vivo

Hongsheng Li, Qiaoyu Wang, Dongli Li, Quanshi Wang, Hubing Wu
Pages: 1307-1313
Published online on: 23 December 2014

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Article

A longitudinal study of CEACAM1 expression in melanoma disease progression

Douglas Zippel, Hani Barlev, Rona Ortenberg, Iris Barshack, Jacob Schachter, Gal Markel
Pages: 1314-1318
Published online on: 30 December 2014

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Article

Upregulation of AIOLOS induces apoptosis and enhances etoposide chemosensitivity in Jurkat leukemia cells

Yong Zhuang, Yuanyuan Lu, Dong Li, Nianzheng Sun, Xiuli Ju
Pages: 1319-1325
Published online on: 18 December 2014

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Article

Clinical and tumor significance of tropomyosin-1 expression levels in renal cell carcinoma

Jin Wang, Jingjing Guan, Zhihua Lu, Jingji Jin, Yong Cai, Chunxi Wang, Fei Wang
Pages: 1326-1334
Published online on: 19 January 2015

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Article

p53-induced microRNA-1246 inhibits the cell growth of human hepatocellular carcinoma cells by targeting NFIB

Quan Zhang, Li-Ye Cao, Shu-Jie Cheng, Ai-Min Zhang, Xiao-Shi Jin, Yong Li
Pages: 1335-1341
Published online on: 14 January 2015

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Article

MicroRNA‑135b regulates the stability of PTEN and promotes glycolysis by targeting USP13 in human colorectal cancers

Shijun Xiang, Jiaqing Fang, Shuyun Wang, Biao Deng, Lin Zhu
Pages: 1342-1348
Published online on: 23 December 2014

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Article

Decreased expression of sestrin 2 predicts unfavorable outcome in colorectal cancer

Jin‑Lai Wei, Zhong‑Xue Fu, Min Fang, Jin‑Bao Guo, Qing‑Ning Zhao, Wei‑Dong Lu, Qiu‑Yuan Zhou
Pages: 1349-1357
Published online on: 30 December 2014

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Article

Recombinant hirudin suppresses the viability, adhesion, migration and invasion of Hep-2 human laryngeal cancer cells

Qian Lu, Mei Lv, Erdong Xu, Fangyu Shao, Ya Feng, Jingru Yang, Lin Shi
Pages: 1358-1364
Published online on: 14 January 2015

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Article

Kinesin superfamily protein 17 contributes to the development of bone cancer pain by participating in NR2B transport in the spinal cord of mice

Ming Liu, Yue Liu, Bailing Hou, Dan Bu, Linyu Shi, Xiaoping Gu, Zhengliang Ma
Pages: 1365-1371
Published online on: 07 January 2015

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Article

Ubenimex inhibits cell proliferation, migration and invasion in renal cell carcinoma: The effect is autophagy-associated

Shuai Liu, Fang Xie, Hafeng Wang, Zheng Liu, Xiaowen Liu, Liang Sun, Zhihong Niu
Pages: 1372-1380
Published online on: 23 December 2014

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Article

Effect of local treatment with adipose tissue-derived mesenchymal stem cells in the early tumorigenesis of osteosarcoma

Sheen-Woo Lee, Tae Joo Jeon, Sandip Biswal
Pages: 1381-1387
Published online on: 08 January 2015

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Article

Inhibitory action of pristimerin on hypoxia‑mediated metastasis involves stem cell characteristics and EMT in PC-3 prostate cancer cells

Jianwei Zuo, Yuanqing Guo, Xinsheng Peng, Yubo Tang, Xintao Zhang, Peiheng He, Shuaihua Li, Qingde Wa, Jinglei Li, Shuai Huang, Dongliang Xu
Pages: 1388-1394
Published online on: 07 January 2015

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Article

Combined treatment with ABT-737 and VX-680 induces apoptosis in Bcl-2- and c-FLIP-overexpressing breast carcinoma cells

Jung Eun Choi, Seon Min Woo, Kyoung-Jin Min, Su Hwan Kang, Soo Jung Lee, Taeg Kyu Kwon
Pages: 1395-1401
Published online on: 15 January 2015

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Article

microRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer

Xiao-Wei Wang, Xue-Qin Xi, Jian Wu, Yi-Yuan Wan, Hong-Xia Hui, Xiu-Feng Cao
Pages: 1402-1410
Published online on: 19 January 2015

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Article

Inhibition of microtubule-associated protein 1 light chain 3B via small-interfering RNA or 3-methyladenine impairs hypoxia-induced HO8910PM and HO8910 epithelial ovarian cancer cell migration and invasion and is associated with RhoA and alterations of the actin cytoskeleton

Zhongyuan Tang, Ning Zhang, Wen Di, Weiping Li
Pages: 1411-1417
Published online on: 20 January 2015

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Article

Molecular markers to assess short-term disease local recurrence in nasopharyngeal carcinoma

Tao Xu, Bojin Su, Chunhua Wang, Sumei Wang, Hecheng Huang, Yunbao Pan, Donghui Wang, Weihong Wei, François X. Claret, Huiling Yang
Pages: 1418-1426
Published online on: 20 January 2015

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Article

Downregulation of peroxiredoxin-1 by β-elemene enhances the radiosensitivity of lung adenocarcinoma xenografts

Guoquan Li, Bingbing Xie, Xiaolong Li, Yinghai Chen, Yinghui Xu, Meng Xu-Welliver, Lijuan Zou
Pages: 1427-1433
Published online on: 19 January 2015

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Article

Diphenylene iodonium interferes with cell cycle progression and induces apoptosis by modulating NAD(P)H oxidase/ROS/cell cycle regulatory pathways in Burkitt's lymphoma cells

Ya Ding, Wenjun Zhu, Rui Sun, Gang Yuan, Dongsheng Zhang, Yuhua Fan, Jian Sun
Pages: 1434-1442
Published online on: 15 January 2015

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Article

Melatonin induces apoptosis in cholangiocarcinoma cell lines by activating the reactive oxygen species-mediated mitochondrial pathway

Umawadee Laothong, Yusuke Hiraku, Shinji Oikawa, Kitti Intuyod, Mariko Murata, Somchai Pinlaor
Pages: 1443-1449
Published online on: 20 January 2015

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Article

Effect of the knockdown of death-associated protein 1 expression on cell adhesion, growth and migration in breast cancer cells

Umar Wazir, Andrew J. Sanders, Ali Wazir, Ruqia Mehmood Baig, Wen G. Jiang, Irina C. Ster, Anup K. Sharma, Kefah Mokbel
Pages: 1450-1458
Published online on: 22 December 2014

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Article

NRSF/REST regulates the mTOR signaling pathway in oral cancer cells

Eugene Cho, Sung-Min Moon, Bo Ram Park, Do Kyung Kim, Byung-Kwon Lee, Chun Sung Kim
Pages: 1459-1464
Published online on: 18 December 2014

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Article

Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Pages: 1465-1474
Published online on: 13 January 2015

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Article

Anti-estrogen‑resistant breast cancer cells are sensitive to cisplatin plus TRAIL treatment

Shuping Yin, Arun K. Rishi, Kaladhar B. Reddy
Pages: 1475-1480
Published online on: 14 January 2015

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Article

Expression of CCN family members correlates with the clinical features of hepatocellular carcinoma

Heyun Zhang, Wenbin Li, Pinbo Huang, Lehang Lin, Hua Ye, Dechen Lin, H. Phillip Koeffler, Jie Wang, Dong Yin
Pages: 1481-1492
Published online on: 08 January 2015

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Article

STAT3 regulates the migration and invasion of a stem‑like subpopulation through microRNA‑21 and multiple targets in hepatocellular carcinoma

Ning Zhang, Wei‑Dong Duan, Jian‑Jun Leng, Liang Zhou, Xing Wang, Yin‑Zhe Xu, Xue‑Dong Wang, Ai‑Qun Zhang, Jia‑Hong Dong
Pages: 1493-1498
Published online on: 08 January 2015

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Hsp90 inhibitor NVP-AUY922 enhances the radiation sensitivity of lung cancer cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors

Shinsuke Hashida, Hiromasa Yamamoto, Kazuhiko Shien, Tomoaki Ohtsuka, Ken Suzawa, Yuho Maki, Masashi Furukawa, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Susumu Kanazawa, Shinichi Toyooka
Pages: 1499-1504
Published online on: 20 January 2015

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Article

PKA/CREB regulates the constitutive promoter activity of the USP22 gene

Jianjun Xiong, Xiaoou Zhou, Zhen Gong, Ting Wang, Chao Zhang, Xiaoyuan Xu, Jianyun Liu, Weidong Li
Pages: 1505-1511
Published online on: 20 January 2015

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Article

Beneficial effect of T follicular helper cells on antibody class switching of B cells in prostate cancer

Jiufeng Tan, Xuefei Jin, Rui Zhao, Xin Wei, Yan Liu, Xiangbo Kong
Pages: 1512-1518
Published online on: 19 December 2014

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Article

Expression of oncogenic HMGN5 increases the sensitivity of prostate cancer cells to gemcitabine

Zhongqiang Guo, Xiaoyu Zhang, Xuesong Li, Feng Xie, Boxing Su, Min Zhang, Liqun Zhou
Pages: 1519-1525
Published online on: 23 December 2014

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Article

A novel bispidinone analog induces S‑phase cell cycle arrest and apoptosis in HeLa human cervical carcinoma cells

Xu Yi, Xin Zhang, Hyunjin Jeong, Yu Mi Shin, Dong Ho Park, Song You, Dong-Kyoo Kim
Pages: 1526-1532
Published online on: 15 January 2015

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Article

Epigallocatechin gallate inhibits human tongue carcinoma cells via HK2‑mediated glycolysis

Feng Gao, Ming Li, Wen-Bin Liu, Zhong-Su Zhou, Rui Zhang, Jun-Ling Li, Ke-Chao Zhou
Pages: 1533-1539
Published online on: 15 January 2015

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Article

Suppression of KCNQ/M (Kv7) potassium channels in the spinal cord contributes to the sensitization of dorsal horn WDR neurons and pain hypersensitivity in a rat model of bone cancer pain

Jie Cai, Dong Fang, Xiao-Dan Liu, Song Li, Juan Ren, Guo-Gang Xing
Pages: 1540-1550
Published online on: 14 January 2015

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Article

Silencing NOB1 enhances doxorubicin antitumor activity of the papillary thyroid carcinoma in vitro and in vivo Retraction in /10.3892/or.2022.8297

Jia Liu, Bing-Fei Dong, Pei-Song Wang, Pei-You Ren, Shuai Xue, Xiao-Νan Zhang, Zhe Han, Guang Chen
Pages: 1551-1559
Published online on: 15 January 2015

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Article

Downregulation of SNAIL sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by regulating the NF-κB pathway

Zhaojun Wan, Huazheng Pan, Shihai Liu, Jingjuan Zhu, Weiwei Qi, Kai Fu, Teng Zhao, Jun Liang
Pages: 1560-1566
Published online on: 20 January 2015

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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