|
1
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics, 2012. CA Cancer J Clin. 62:10–29. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Cunningham D, Atkin W, Lenz HJ, et al:
Colorectal cancer. Lancet. 375:1030–1047. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Labianca R, Beretta GD, Kildani B, et al:
Colon cancer. Crit Rev Oncol Hematol. 74:106–133. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Pihl E, Hughes ES, McDermott FT, Milne BJ
and Price AB: Disease-free survival and recurrence after resection
of colorectal carcinoma. J Surg Oncol. 16:333–341. 1981. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Cresanta JL: Epidemiology of cancer in the
United States. Prim Care. 19:419–441. 1992.PubMed/NCBI
|
|
6
|
Greenwald P: Colon cancer overview.
Cancer. 70(Suppl 5): S1206–S1215. 1992. View Article : Google Scholar
|
|
7
|
Zhang H, Qian Y, Liu Y, et al: Celastrus
orbiculatus extract induces mitochondrial-mediated apoptosis in
human hepatocellular carcinoma cells. J Tradit Chin Med.
32:621–626. 2012. View Article : Google Scholar
|
|
8
|
Liu J and Liu Y: Influence of Erbanxiao
solution on inhibiting angiogenesis in stasis toxin stagnation of
non-small cell lung cancer. J Tradit Chin Med. 33:303–306. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Kang J, Lee N, Ahn Y and Lee H: Study on
improving blood flow with Korean red ginseng substances using
digital infrared thermal imaging and Doppler sonography:
randomized, double blind, placebo-controlled clinical trial with
parallel design. J Tradit Chin Med. 33:39–45. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Surh YJ: Anti-tumor promoting potential of
selected spice ingredients with antioxidative and anti-inflammatory
activities: a short review. Food Chem Toxicol. 40:1091–1097. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Su Y, Li G, Zhang X, et al: JSI-124
inhibits glioblastoma multiforme cell proliferation through G2/M
cell cycle arrest and apoptosis augment. Cancer Biol Ther.
7:1243–1249. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
van Kester MS, Out-Luiting JJ, von dem
Borne PA, Willemze R, Tensen CP and Vermeer MH: Cucurbitacin I
inhibits Stat3 and induces apoptosis in Sézary cells. J Invest
Dermatol. 128:1691–1695. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Blaskovich MA, Sun J, Cantor A, Turkson J,
Jove R and Sebti SM: Discovery of JSI-124 (cucurbitacin I), a
selective Janus kinase/signal transducer and activator of
transcription 3 signaling pathway inhibitor with potent antitumor
activity against human and murine cancer cells in mice. Cancer Res.
63:1270–1279. 2003.PubMed/NCBI
|
|
14
|
Chen JC, Chiu MH, Nie RL, Cordell GA and
Qiu SX: Cucurbitacins and cucurbitane glycosides: structures and
biological activities. Nat Prod Rep. 22:386–399. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Chen CL, Hsieh FC, Lieblein JC, et al:
Stat3 activation in human endometrial and cervical cancers. Br J
Cancer. 96:591–599. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Lo HW, Cao X, Zhu H and Ali-Osman F:
Constitutively activated STAT3 frequently coexpresses with
epidermal growth factor receptor in high-grade gliomas and
targeting STAT3 sensitizes them to Iressa and alkylators. Clin
Cancer Res. 14:6042–6054. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kim HJ, Park JH and Kim JK:
Cucurbitacin-I, a natural cell-permeable triterpenoid isolated from
Cucurbitaceae, exerts potent anticancer effect in colon cancer.
Chem Biol Interact. 219:1–8. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Gu L, Feng J, Xu H, Luo M and Su D:
Polyphyllin I inhibits proliferation and metastasis of ovarian
cancer cell line HO-8910PM in vitro. J Tradit Chin Med. 33:325–333.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Luo XS, Wu XW and Gu Q: An experimental
study of a modified Dahuang Zhechong pill on the - angiogenesis of
RF/6A cells in vitro. J Tradit Chin Med. 32:75–81. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Lui VW, Boehm AL, Koppikar P, et al:
Antiproliferative mechanisms of a transcription factor decoy
targeting signal transducer and activator of transcription (STAT)
3: the role of STAT1. Mol Pharmacol. 71:1435–1443. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Hsu HS, Huang PI, Chang YL, et al:
Cucurbitacin I inhibits tumorigenic ability and enhances
radiochemosensitivity in nonsmall cell lung cancer-derived
CD133-positive cells. Cancer. 117:2970–2985. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Chen YW, Chen KH, Huang PI, et al:
Cucurbitacin I suppressed stem-like property and enhanced
radiation-induced apoptosis in head and neck squamous
carcinoma-derived CD44+ALDH1+ cells. Mol
Cancer Ther. 9:2879–2892. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Alghasham AA: Cucurbitacins - a promising
target for cancer therapy. Int J Health Sci. 7:77–89. 2013.
View Article : Google Scholar
|
|
24
|
Ren Y, Yu K, Sun S, et al: JSI124 inhibits
breast cancer cell growth by suppressing the function of B cells
via the downregulation of signal transducer and activator of
transcription 3. Oncol Lett. 8:928–932. 2014.PubMed/NCBI
|
|
25
|
Ishdorj G, Johnston JB and Gibson SB:
Inhibition of constitutive activation of STAT3 by curcurbitacin-I
(JSI-124) sensitized human B-leukemia cells to apoptosis. Mol
Cancer Ther. 9:3302–3314. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Björklund M and Koivunen E:
Gelatinase-mediated migration and invasion of cancer cells. Biochim
Biophys Acta. 1755:37–69. 2005.PubMed/NCBI
|
|
27
|
Li X, Yang G, Li X, et al: Traditional
Chinese medicine in cancer care: a review of controlled clinical
studies published in Chinese. PLoS One. 8:e603382013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Knecht DA, LaFleur RA, Kahsai AW, Argueta
CE, Beshir AB and Fenteany G: Cucurbitacin I inhibits cell motility
by indirectly interfering with actin dynamics. PLoS One.
5:e140392010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Maloney KN, Fujita M, Eggert US, et al:
Actin-aggregating cucurbitacins from Physocarpus capitatus. J Nat
Prod. 71:1927–1929. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Abdulghani J, Gu L, Dagvadorj A, et al:
Stat3 promotes metastatic progression of prostate cancer. Am J
Pathol. 172:1717–1728. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Deng JY, Sun D, Liu XY, Pan Y and Liang H:
STAT-3 correlates with lymph node metastasis and cell survival in
gastric cancer. World J Gastroenterol. 16:5380–5387. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Dauer DJ, Ferraro B, Song L, et al: Stat3
regulates genes common to both wound healing and cancer. Oncogene.
24:3397–3408. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Xie TX, Huang FJ, Aldape KD, et al:
Activation of stat3 in human melanoma promotes brain metastasis.
Cancer Res. 66:3188–3196. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Li WC, Ye SL, Sun RX, et al: Inhibition of
growth and metastasis of human hepatocellular carcinoma by
antisense oligonucleotide targeting signal transducer and activator
of transcription 3. Clin Cancer Res. 12:7140–7148. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Silver DL, Naora H, Liu J, Cheng W and
Montell DJ: Activated signal transducer and activator of
transcription (STAT) 3: localization in focal adhesions and
function in ovarian cancer cell motility. Cancer Res. 64:3550–3558.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Horiguchi A, Oya M, Shimada T, Uchida A,
Marumo K and Murai M: Activation of signal transducer and activator
of transcription 3 in renal cell carcinoma: a study of incidence
and its association with pathological features and clinical
outcome. J Urol. 168:762–765. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kusaba T, Nakayama T, Yamazumi K, et al:
Expression of p-STAT3 in human colorectal adenocarcinoma and
adenoma; correlation with clinicopathological factors. J Clin
Pathol. 58:833–838. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Ihle JN: The Stat family in cytokine
signaling. Curr Opin Cell Biol. 13:211–217. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Levy DE and Darnell JE Jr: Stats:
transcriptional control and biological impact. Nat Rev Mol Cell
Biol. 3:651–662. 2002. View
Article : Google Scholar : PubMed/NCBI
|
|
40
|
Chang CJ, Chiang CH, Song WS, et al:
Inhibition of phosphorylated STAT3 by cucurbitacin I enhances
chemoradiosensitivity in medulloblastoma-derived cancer stem cells.
Childs Nerv Syst. 28:363–373. 2012. View Article : Google Scholar : PubMed/NCBI
|
