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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April-2015 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

MicroRNAs in renal cell carcinoma: A systematic review of clinical implications (Review)

Ming Li, Ying Wang, Yongsheng Song, Renge Bu, Bo Yin, Xiang Fei, Qizhen Guo, Bin Wu
Pages: 1571-1578
Published online on: 13 February 2015

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Article Open Access

Inhibitory effect of maple syrup on the cell growth and invasion of human colorectal cancer cells

Tetsushi Yamamoto, Kentaro Uemura, Kaho Moriyama, Kuniko Mitamura, Atsushi Taga
Pages: 1579-1584
Published online on: 02 February 2015

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Article Open Access

A vaccine strategy with multiple prostatic acid phosphatase-fused cytokines for prostate cancer treatment

Kei Fujio, Masami Watanabe, Hideo Ueki, Shun-Ai Li, Rie  Kinoshita, Kazuhiko  Ochiai, Junichiro  Futami, Toyohiko Watanabe, Yasutomo Nasu, Hiromi Kumon
Pages: 1585-1592
Published online on: 29 January 2015

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Article Open Access

Development of tumor-specific caffeine-potentiated chemotherapy using a novel drug delivery system with Span 80 nano-vesicles

Hiroshi Nakata, Tatsuhiko Miyazaki, Tomoyuki Iwasaki, Atsushi Nakamura, Teruki Kidani, Kenshi Sakayama, Junya Masumoto, Hiromasa Miura
Pages: 1593-1598
Published online on: 29 January 2015

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Article Open Access

Proapoptotic effect of endocannabinoids in prostate cancer cells

O. Orellana-Serradell, C. E. Poblete, C. Sanchez, E. A. Castellón, I. Gallegos, C. Huidobro, M. N. Llanos, H. R. Contreras
Pages: 1599-1608
Published online on: 21 January 2015

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Article Open Access

Constitutive activation of NF-κB signaling by NOTCH1 mutations in chronic lymphocytic leukemia

Zhen-Shu Xu, Ju-Shun Zhang, Jing-Yan Zhang, Shun-Quan Wu, Dong-Lian Xiong, Hui-Jun Chen, Zhi-Zhe Chen, Rong Zhan
Pages: 1609-1614
Published online on: 29 January 2015

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Article Open Access

Human immunodeficiency virus-negative plasmablastic lymphoma: A comprehensive analysis of 114 cases

Min Liu, Bailong Liu, Bin Liu, Qiang Wang, Lijuan Ding, Chengcheng Xia, Lihua Dong
Pages: 1615-1620
Published online on: 17 February 2015

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Article Open Access

Akt‑mediated phosphorylation of Oct4 is associated with the proliferation of stem‑like cancer cells

Qing‑Wei Zhao, Yan‑Wen Zhou, Wen‑Xin Li, Bo Kang, Xiao‑Qian Zhang, Ying Yang, Jie Cheng, Sheng‑Yong Yin, Ying Tong, Jian‑Qin He, Hang‑Ping Yao, Min Zheng, Ying‑Jie Wang
Pages: 1621-1629
Published online on: 27 January 2015

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Article Open Access

Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extracellular signal-regulated kinases 1/2

Qiu-Yu Zhang, Lin-Qing Wu, Tao Zhang, Yan-Fei Han, Xu Lin
Pages: 1630-1638
Published online on: 04 February 2015

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Article Open Access

High miR-24 expression is associated with risk of relapse and poor survival in acute leukemia

Jorge Organista-Nava, Yazmín Gómez-Gómez, Berenice Illades-Aguiar, Luz Del Carmen Alarcón-Romero, Mónica Virginia Saavedra-Herrera, Ana Bertha Rivera‑Ramírez, Víctor Hugo Garzón-Barrientos, Marco Antonio Leyva-Vázquez
Pages: 1639-1649
Published online on: 06 February 2015

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Article

Downregulation of p53 promotes in vitro perineural invasive activity of human salivary adenoid cystic carcinoma cells through epithelial-mesenchymal transition-like changes

Xiangming Yang, Da Jing, Lijun Liu, Zhiyuan Shen, Jun Ju, Chao Ma, Moyi Sun
Pages: 1650-1656
Published online on: 26 January 2015

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Article

Hepatic expression of the Sptlc3 subunit of serine palmitoyltransferase is associated with the development of hepatocellular carcinoma in a mouse model of nonalcoholic steatohepatitis

Yozo Yoshimine, Hirofumi Uto, Kotaro Kumagai, Seiichi Mawatari, Shiho Arima, Rie Ibusuki, Kumiko Mera, Tsuyoshi Nosaki, Shuji Kanmura, Masatsugu Numata, Tsutomu Tamai, Akihiro Moriuchi, Hirohito Tsubouchi, Akio Ido
Pages: 1657-1666
Published online on: 21 January 2015

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Article

Anaplastic lymphoma kinase protein expression, genetic abnormalities, and phosphorylation in soft tissue tumors: Phosphorylation is associated with recurrent metastasis

Yukinao Ishibashi, Hiroaki Miyoshi, Koji Hiraoka, Fumiko Arakawa, Toshiaki Haraguchi, Shinji Nakashima, Toshihiro Hashiguchi, Takanori Shoda, Tetsuya Hamada, Takahiro Okawa, Fujio Higuchi, Naoto Shiba, Kensei Nagata, Koichi Ohshima
Pages: 1667-1674
Published online on: 16 February 2015

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Article

Honeybee venom possesses anticancer and antiviral effects by differential inhibition of HPV E6 and E7 expression on cervical cancer cell line

Yong-Wan Kim, Pankaj Kumar Chaturvedi, Sung  Nam Chun, Yang Gu Lee, Woong Shick Ahn
Pages: 1675-1682
Published online on: 28 January 2015

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Article

Maslinic acid potentiates the antitumor activities of gemcitabine in vitro and in vivo by inhibiting NF-κB-mediated survival signaling pathways in human gallbladder cancer cells

Yong Yu, Jinghan Wang, Nianxin Xia, Bin Li, Xiaoqing Jiang
Pages: 1683-1690
Published online on: 28 January 2015

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Article

Emodin attenuates radioresistance induced by hypoxia in HepG2 cells via the enhancement of PARP1 cleavage and inhibition of JMJD2B

Sang Youn Hwang, Kyu Heo, Joon Seok Kim, Jung Woo Im, Sun Mi Lee, Mong Cho, Dae Hwan Kang, Jeong Heo, Jun Woo Lee, Cheol Won Choi, Kwangmo Yang
Pages: 1691-1698
Published online on: 21 January 2015

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Article

BRD4 promotes pancreatic ductal adenocarcinoma cell proliferation and enhances gemcitabine resistance

Yong-Hui Wang, Ya-Na Sui, Kai Yan, Li-Shan Wang, Fei Wang, Jia-Hua Zhou
Pages: 1699-1706
Published online on: 30 January 2015

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Article

MicroRNA-182 inhibits proliferation through targeting oncogenic ANUBL1 in gastric cancer

Lin Tang, Feng Chen, Er-Jun Pang, Zhi-Qi Zhang, Bing-Wei Jin, Wei-Feng Dong
Pages: 1707-1716
Published online on: 12 February 2015

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Article

EGR1 regulates radiation-induced apoptosis in head and neck squamous cell carcinoma

Tae Mi Yoon, Sun-Ae Kim, Dong Hoon Lee, Joon Kyoo Lee, Young-Lan Park, Kyung-Hwa Lee, Ik-Joo Chung, Young-Eun Joo, Sang Chul Lim
Pages: 1717-1722
Published online on: 22 January 2015

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Article

Inhibition of c-Myc by let-7b mimic reverses mutidrug resistance in gastric cancer cells

Xiaojun Yang, Hui Cai, Yuhe Liang, Lin Chen, Xiangdong Wang, Ruohuang Si, Kunpeng Qu, Zebin Jiang, Bingqiang Ma, Changfeng Miao, Jing Li, Bin Wang, Peng Gao
Pages: 1723-1730
Published online on: 28 January 2015

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Article

Violacein anticancer activity is enhanced under hypoxia

Saeed M. Hashimi, Tiefeng Xu, Ming Q. Wei
Pages: 1731-1736
Published online on: 04 February 2015

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Article

Blockage of PTPRJ promotes cell growth and resistance to 5-FU through activation of JAK1/STAT3 in the cervical carcinoma cell line C33A

Chun-Mei Yan, Ying-Ling Zhao, Hong-Yi Cai, Guo-Ying Miao, Wen Ma
Pages: 1737-1744
Published online on: 29 January 2015

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Article

OCT4 pseudogene 5 upregulates OCT4 expression to promote proliferation by competing with miR-145 in endometrial carcinoma

Mingzhu Bai, Mu Yuan, Hong Liao, Jiazhou Chen, Binying Xie, Dong Yan, Xiaowei Xi, Xianming Xu, Zhenbo Zhang, Youji Feng
Pages: 1745-1752
Published online on: 29 January 2015

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Article

Capecitabine metronomic chemotherapy inhibits the proliferation of gastric cancer cells through anti-angiogenesis

Fei Yuan, Hailong Shi, Jun Ji, Qu Cai, Xuehua Chen, Yingyan Yu, Bingya Liu, Zhenggang Zhu, Jun Zhang
Pages: 1753-1762
Published online on: 29 January 2015

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Article

Niclosamide inhibits the proliferation of human osteosarcoma cell lines by inducing apoptosis and cell cycle arrest

Zonghuan Li, Yifeng Yu, Shaoxing Sun, Baiwen Qi, Weiyang Wang, Aixi Yu
Pages: 1763-1768
Published online on: 29 January 2015

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Article

Geranylgeranylacetone suppresses colitis‑related mouse colon carcinogenesis

Takuya Inoue, Naoki Yorifuji, Munetaka Iguchi, Kaori Fujiwara, Kazuki Kakimoto, Sadaharu Nouda, Toshihiko Okada, Ken Kawakami, Yosuke Abe, Toshihisa Takeuchi, Kazuhide Higuchi
Pages: 1769-1774
Published online on: 10 February 2015

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Article

Berberine induces FasL-related apoptosis through p38 activation in KB human oral cancer cells

Jae-Sung Kim, Dahye Oh, Min-Ji Yim, Jin-Ju  Park, Kyeong-Rok Kang, In-A  Cho, Sung-Min  Moon, Ji-Su  Oh, Jae-Seek You, Chun Sung Kim, Do  Kyung Kim, Sook‑Young Lee, Gyeong-Je Lee, Hee-Jeong Im, Su-Gwan Kim
Pages: 1775-1782
Published online on: 29 January 2015

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Article

Asporin participates in gastric cancer cell growth and migration by influencing EGF receptor signaling

Qian Ding, Mei Zhang, Can Liu
Pages: 1783-1790
Published online on: 09 February 2015

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Article

Adenovirus-mediated LRIG1 expression enhances the chemosensitivity of bladder cancer cells to cisplatin

Zejun Yan, Junhui Jiang, Fan Li, Weiming Yang, Guohai Xie, Cheng Zhou, Shujie Xia, Yue Cheng
Pages: 1791-1798
Published online on: 16 February 2015

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Article

Ubiquilin 2 enhances osteosarcoma progression through resistance to hypoxic stress

Shinji Tsukamoto, Keiji Shimada, Kanya Honoki, Akira Kido, Manabu Akahane, Yasuhito Tanaka, Noboru Konishi
Pages: 1799-1806
Published online on: 09 February 2015

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Article

Overexpression of Tiam1 promotes the progression of laryngeal squamous cell carcinoma

Shuang Wang, Shisheng Li, Qinglai Tang, Shu Yang, Shuhui Wang, Jiajia Liu, Mi Yang, Xinming Yang
Pages: 1807-1814
Published online on: 05 February 2015

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Article

Recombinant nematode anticoagulant protein c2 inhibits cell invasion by decreasing uPA expression in NSCLC cells

Yu Tong, Jun Yue, Meng Mao, Qingqing Liu, Jing Zhou, Jiyun Yang
Pages: 1815-1822
Published online on: 10 February 2015

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Article

Induction and mechanism of HeLa cell apoptosis by 9-oxo‑10, 11-dehydroageraphorone from Eupatorium adenophorum

Fei Liao, Yanchun Hu, Lei Wu, Hui Tan, Biao Luo, Yajun He, Yan Qiao, Quan Mo, Ya Wang, Zhicai Zuo, Junliang Deng, Yahui Wei
Pages: 1823-1827
Published online on: 02 February 2015

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Effects of PTEN on the proliferation and apoptosis of colorectal cancer cells via the phosphoinositol-3-kinase/Akt pathway

Yan Sun, Hua Tian, Lin Wang
Pages: 1828-1836
Published online on: 16 February 2015

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Article

Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer

Yoshinori Imamura, Toru Mukohara, Yohei Shimono, Yohei Funakoshi, Naoko Chayahara, Masanori Toyoda, Naomi Kiyota, Shintaro Takao, Seishi Kono, Tetsuya Nakatsura, Hironobu Minami
Pages: 1837-1843
Published online on: 29 January 2015

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Article

C5aR is frequently expressed in metastatic renal cell carcinoma and plays a crucial role in cell invasion via the ERK and PI3 kinase pathways

Yoshihiro Maeda, Yoshiaki Kawano, Yoshihiro Wada, Junji Yatsuda, Takanobu Motoshima, Yoji Murakami, Ken Kikuchi, Takahisa Imamura, Masatoshi Eto
Pages: 1844-1850
Published online on: 13 February 2015

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Article

Downregulation of cathepsin L suppresses cancer invasion and migration by inhibiting transforming growth factor‑β‑mediated epithelial‑mesenchymal transition

Qingqing Zhang, Meiling Han, Wenjuan Wang, Yunzhen Song, Gang Chen, Zhong Wang, Zhongqin Liang
Pages: 1851-1859
Published online on: 27 January 2015

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Article

AURKA upregulation plays a role in fibroblast-reduced gefitinib sensitivity in the NSCLC cell line HCC827

Jia Chen, Huiqi Lu, Wang Zhou, Huabin Yin, Lishuang Zhu, Chang Liu, Pengfei Zhang, Huimin Hu, Yili Yang, Huanxing Han
Pages: 1860-1866
Published online on: 29 January 2015

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Article

Cucurbitacin I inhibits cell migration and invasion and enhances chemosensitivity in colon cancer

Junmin Song, Hongxiang Liu, Zhen Li, Chao Yang, Chaojie Wang
Pages: 1867-1871
Published online on: 26 January 2015

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Article

STAT3 cooperates with Twist to mediate epithelial-mesenchymal transition in human hepatocellular carcinoma cells

Chuanhai Zhang, Fenglin Guo, Geliang Xu, Jie Ma, Feng Shao
Pages: 1872-1882
Published online on: 04 February 2015

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Article

HES 1 is essential for chemoresistance induced by stellate cells and is associated with poor prognosis in pancreatic cancer

Feng Cao, Jia Li, Haichen Sun, Shuang Liu, Yeqing Cui, Fei Li
Pages: 1883-1889
Published online on: 09 February 2015

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Article

miR-26b inhibits proliferation, migration, invasion and apoptosis induction via the downregulation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 driven glycolysis in osteosarcoma cells

Jing-Yu Du, Li-Feng Wang, Quan Wang, Lie-Dao Yu
Pages: 1890-1898
Published online on: 12 February 2015

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Article

Apicidin inhibits cell growth by downregulating IGF-1R in salivary mucoepidermoid carcinoma cells

Mee-Young Ahn, Ji-Wee Ahn, Hyung-Sik Kim, Jun Lee, Jung-Hoon Yoon
Pages: 1899-1907
Published online on: 02 February 2015

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Article

Protein tyrosine phosphatase receptor type O expression in the tumor niche correlates with reduced tumor growth, angiogenesis, circulating tumor cells and metastasis of breast cancer

Zhao Liu, Jiajie Hou, Lidong Ren, Jing He, Beicheng Sun, Lu-Zhe Sun, Shui Wang
Pages: 1908-1914
Published online on: 29 January 2015

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Article

N,N'-di-(m-methylphenyi)-3,6-dimethyl-1,4-dihydro-1,2,4,5-tetrazine-1,4-dicarboamide (ZGDHu-1) suppresses the proliferation of PANC-1 pancreatic cancer cells via apoptosis and G2/M cell cycle arrest

Su-Feng Chen, Jun Xia, Ya-Ping Lv, Jin-Lin Liu, Wan-Xiang Li, Xi-Ping Yu, Wei-Xiao Hu, Yong-Lie Zhou
Pages: 1915-1921
Published online on: 16 February 2015

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Article

Pien Tze Huang inhibits liver metastasis by targeting TGF-β signaling in an orthotopic model of colorectal cancer

Wei Lin, Qunchuan Zhuang, Liangpu Zheng, Zhiyun Cao, Aling Shen, Qiongyu Li, Caixuan Fu, Jianyu Feng, Jun Peng
Pages: 1922-1928
Published online on: 05 February 2015

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Article

GPER in CAFs regulates hypoxia-driven breast cancer invasion in a CTGF-dependent manner

Juan Ren, Hui Guo, Huili Wu, Tao Tian, Danfeng Dong, Yuelang Zhang, Yanxia Sui, Yong Zhang, Dongli Zhao, Shufeng Wang, Zongfang Li, Xiaozhi Zhang, Rui Liu, Jianshneg Qian, Hongxia Wei, Wenjun Jiang, Ya Liu, Yi Li
Pages: 1929-1937
Published online on: 03 February 2015

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Article

Angiomotin promotes breast cancer cell proliferation and invasion

Meng Lv, Meiling Lv, Ling Chen, Tianjie Qin, Xiao Zhang, Peijun Liu, Jin Yang
Pages: 1938-1946
Published online on: 03 February 2015

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Article

Evaluation of preventive and therapeutic activity of novel non-steroidal anti-inflammatory drug, CG100649, in colon cancer: Increased expression of TNF-related apoptosis-inducing ligand receptors enhance the apoptotic response to combination treatment with TRAIL

Jong Kyu Woo, Ju-Hee Kang, Yeong-Su Jang, Seonggu Ro, Joong Myung Cho, Hwan-Mook Kim, Sang-Jin Lee, Seung Hyun Oh
Pages: 1947-1955
Published online on: 10 February 2015

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Article

Decreased expression of SCUBE2 is associated with progression and prognosis in colorectal cancer

Qi Song, Chuanwei Li, Xiaodong Feng, Ailian Yu, Huamei Tang, Zhihai Peng, Xuechun Wang
Pages: 1956-1964
Published online on: 09 February 2015

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Article

OY-TES-1 may regulate the malignant behavior of liver cancer via NANOG, CD9, CCND2 and CDCA3: A bioinformatic analysis combine with RNAi and oligonucleotide microarray

Qiping Hu, Jun Fu, Bin Luo, Miao Huang, Wenwen Guo, Yongda Lin, Xiaoxun Xie, Shaowen Xiao
Pages: 1965-1975
Published online on: 10 February 2015

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Article

(-)-Epigallocatechin-3-gallate reverses the expression of various tumor-suppressor genes by inhibiting DNA methyltransferases and histone deacetylases in human cervical cancer cells

Munawwar Ali Khan, Arif Hussain, Madhumitha Kedhari Sundaram, Usama Alalami, Dian Gunasekera, Laveena Ramesh, Amina Hamza, Uzma Quraishi
Pages: 1976-1984
Published online on: 13 February 2015

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Article

Cross-platform meta-analysis of multiple gene expression profiles identifies novel expression signatures in acquired anthracycline-resistant breast cancer

Young Seok Lee, Seung Won Ryu, Se Jong Bae, Tae Hwan Park, Kang Kwon, Yun Hee Noh, Sung Young Kim
Pages: 1985-1993
Published online on: 17 February 2015

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Article

Synergistic anti-proliferative effect of metformin and sorafenib on growth of anaplastic thyroid cancer cells and their stem cells

Guofang Chen, Diana Nicula, Kostja Renko, Michael Derwahl
Pages: 1994-2000
Published online on: 16 February 2015

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Cytokinesis failure and successful multipolar mitoses drive aneuploidy in glioblastoma cells

Sergej Telentschak, Mark Soliwoda, Klaus Nohroudi, Klaus Addicks, Franz-Josef Klinz
Pages: 2001-2008
Published online on: 27 January 2015

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Article

Cytotoxic and radiosensitizing effects of FAK targeting in human glioblastoma cells in vitro

Katja Storch, Andre Sagerer, Nils Cordes
Pages: 2009-2016
Published online on: 27 January 2015

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Article

Assessment of MLL methyltransferase gene expression in larynx carcinoma

David Livingstone Alves Figueiredo, Doralina do Amaral Rabello, Dalila Luciola Zanette, Fabiano Pinto Saggioro, Rui Celso Martins Mamede, Marco Antonio Zago, Wilson Araújo da Silva, Felipe Saldanha-Araújo, Fabio Pittella Silva
Pages: 2017-2022
Published online on: 28 January 2015

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Article

Increased chemoresistance to paclitaxel in the MCF10AT series of human breast epithelial cancer cells

Soo-Jeong Lim, Hyeon Gyeom Choi, Chae Kyung Jeon, So Hee Kim
Pages: 2023-2030
Published online on: 02 February 2015

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3,3'-Diindolylmethane potentiates paclitaxel-induced antitumor effects on gastric cancer cells through the Akt/FOXM1 signaling cascade

Hua Jin, Man Hee Park, Soo Mi Kim
Pages: 2031-2036
Published online on: 28 January 2015

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Article

Krüppel-like factor 10 null mice exhibit lower tumor incidence and suppressed cellular proliferation activity following chemically induced liver tumorigenesis

Seung-Ho Heo, Eui-Suk Jeong, Kyoung-Sun Lee, Jin‑Hee Seo, Woon-Kyu Lee, Yang-Kyu Choi
Pages: 2037-2044
Published online on: 13 February 2015

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Ara-C increases gastric cancer cell invasion by upregulating CD-147-MMP-2/MMP‑9 via the ERK signaling pathway

Guang-Lin Yang, Hai-Rong Tao, Han-Wei Wang, Yun Sun, Li-Di Zhang, Chao Zhang, Wei He, Mang-Hua Xu, Jiang-Min Zhao, Feng-Hou Gao
Pages: 2045-2051
Published online on: 23 January 2015

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Article

Wnt7A is a putative prognostic and chemosensitivity marker in human malignant pleural mesothelioma

Tomomi Hirata, Qingfeng Zheng, Zhao Chen, Hiroyasu Kinoshita, Junichi Okamoto, Johannes Kratz, Hui Li, Natalie Lui, Hanh Do, Tiffany Cheng, Hsin-Hui Katty Tseng, Kiyoshi Koizumi, Kazuo Shimizu, Hai‑Meng Zhou, David Jablons, Biao He
Pages: 2052-2060
Published online on: 29 January 2015

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Article

miR-375 inhibits cell growth and correlates with clinical outcomes in tongue squamous cell carcinoma

Lingfei Jia, Yiping Huang, Yunfei Zheng, Mingyue Lyu, Chunan Zhang, Zhen Meng, Yehua Gan, Guangyan Yu
Pages: 2061-2071
Published online on: 28 January 2015

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Article

Selective anticancer activity of hirsutine against HER2‑positive breast cancer cells by inducing DNA damage

Chenghua Lou, Satoru Yokoyama, Ikuo Saiki, Yoshihiro Hayakawa
Pages: 2072-2076
Published online on: 12 February 2015

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Article

Baicalein suppresses 17-β-estradiol-induced migration, adhesion and invasion of breast cancer cells via the G protein-coupled receptor 30 signaling pathway

Dandan Shang, Zheng Li, Zhuxia Zhu, Huamei Chen, Lujun Zhao, Xudong Wang, Yan Chen
Pages: 2077-2085
Published online on: 05 February 2015

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Article

PGC-1α is responsible for survival of multiple myeloma cells under hyperglycemia and chemotherapy

Wen Yu, Dedong Cao, Hao Zhou, Yu Hu, Tao Guo
Pages: 2086-2092
Published online on: 17 February 2015

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Correction Open Access

[Corrigendum] microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is associated with liver metastasis in colorectal cancer

Yujun Zhang, Xiangjun He, Yulan Liu, Yingjiang Ye, Hui Zhang, Peiying He, Qi Zhang, Lingyi Dong, Yujing Liu, Jianqiang Dong
Pages: 2093-2093
Published online on: 30 January 2015

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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