Journal Articles

Review Open Access

MicroRNAs in renal cell carcinoma: A systematic review of clinical implications (Review)

Ming Li, Ying Wang, Yongsheng Song, Renge Bu, Bo Yin, Xiang Fei, Qizhen Guo, Bin Wu

Pages: 1571-1578 Published online on: 13 February 2015
Article Open Access

Inhibitory effect of maple syrup on the cell growth and invasion of human colorectal cancer cells

Tetsushi Yamamoto, Kentaro Uemura, Kaho Moriyama, Kuniko Mitamura, Atsushi Taga

Pages: 1579-1584 Published online on: 02 February 2015
Article Open Access

A vaccine strategy with multiple prostatic acid phosphatase-fused cytokines for prostate cancer treatment

Kei Fujio, Masami Watanabe, Hideo Ueki, Shun-Ai Li, Rie  Kinoshita, Kazuhiko  Ochiai, Junichiro  Futami, Toyohiko Watanabe, Yasutomo Nasu, Hiromi Kumon

Pages: 1585-1592 Published online on: 29 January 2015
Article Open Access

Development of tumor-specific caffeine-potentiated chemotherapy using a novel drug delivery system with Span 80 nano-vesicles

Hiroshi Nakata, Tatsuhiko Miyazaki, Tomoyuki Iwasaki, Atsushi Nakamura, Teruki Kidani, Kenshi Sakayama, Junya Masumoto, Hiromasa Miura

Pages: 1593-1598 Published online on: 29 January 2015
Article Open Access

Proapoptotic effect of endocannabinoids in prostate cancer cells

O. Orellana-Serradell, C. E. Poblete, C. Sanchez, E. A. Castellón, I. Gallegos, C. Huidobro, M. N. Llanos, H. R. Contreras

Pages: 1599-1608 Published online on: 21 January 2015
Article Open Access

Constitutive activation of NF-κB signaling by NOTCH1 mutations in chronic lymphocytic leukemia

Zhen-Shu Xu, Ju-Shun Zhang, Jing-Yan Zhang, Shun-Quan Wu, Dong-Lian Xiong, Hui-Jun Chen, Zhi-Zhe Chen, Rong Zhan

Pages: 1609-1614 Published online on: 29 January 2015
Article Open Access

Human immunodeficiency virus-negative plasmablastic lymphoma: A comprehensive analysis of 114 cases

Min Liu, Bailong Liu, Bin Liu, Qiang Wang, Lijuan Ding, Chengcheng Xia, Lihua Dong

Pages: 1615-1620 Published online on: 17 February 2015
Article Open Access

Akt‑mediated phosphorylation of Oct4 is associated with the proliferation of stem‑like cancer cells

Qing‑Wei Zhao, Yan‑Wen Zhou, Wen‑Xin Li, Bo Kang, Xiao‑Qian Zhang, Ying Yang, Jie Cheng, Sheng‑Yong Yin, Ying Tong, Jian‑Qin He, Hang‑Ping Yao, Min Zheng, Ying‑Jie Wang

Pages: 1621-1629 Published online on: 27 January 2015
Article Open Access

Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extracellular signal-regulated kinases 1/2

Qiu-Yu Zhang, Lin-Qing Wu, Tao Zhang, Yan-Fei Han, Xu Lin

Pages: 1630-1638 Published online on: 04 February 2015
Article Open Access

High miR-24 expression is associated with risk of relapse and poor survival in acute leukemia

Jorge Organista-Nava, Yazmín Gómez-Gómez, Berenice Illades-Aguiar, Luz Del Carmen Alarcón-Romero, Mónica Virginia Saavedra-Herrera, Ana Bertha Rivera‑Ramírez, Víctor Hugo Garzón-Barrientos, Marco Antonio Leyva-Vázquez

Pages: 1639-1649 Published online on: 06 February 2015
Article

Downregulation of p53 promotes in vitro perineural invasive activity of human salivary adenoid cystic carcinoma cells through epithelial-mesenchymal transition-like changes

Xiangming Yang, Da Jing, Lijun Liu, Zhiyuan Shen, Jun Ju, Chao Ma, Moyi Sun

Pages: 1650-1656 Published online on: 26 January 2015
Article

Hepatic expression of the Sptlc3 subunit of serine palmitoyltransferase is associated with the development of hepatocellular carcinoma in a mouse model of nonalcoholic steatohepatitis

Yozo Yoshimine, Hirofumi Uto, Kotaro Kumagai, Seiichi Mawatari, Shiho Arima, Rie Ibusuki, Kumiko Mera, Tsuyoshi Nosaki, Shuji Kanmura, Masatsugu Numata, Tsutomu Tamai, Akihiro Moriuchi, Hirohito Tsubouchi, Akio Ido

Pages: 1657-1666 Published online on: 21 January 2015
Article

Anaplastic lymphoma kinase protein expression, genetic abnormalities, and phosphorylation in soft tissue tumors: Phosphorylation is associated with recurrent metastasis

Yukinao Ishibashi, Hiroaki Miyoshi, Koji Hiraoka, Fumiko Arakawa, Toshiaki Haraguchi, Shinji Nakashima, Toshihiro Hashiguchi, Takanori Shoda, Tetsuya Hamada, Takahiro Okawa, Fujio Higuchi, Naoto Shiba, Kensei Nagata, Koichi Ohshima

Pages: 1667-1674 Published online on: 16 February 2015
Article

Honeybee venom possesses anticancer and antiviral effects by differential inhibition of HPV E6 and E7 expression on cervical cancer cell line

Yong-Wan Kim, Pankaj Kumar Chaturvedi, Sung  Nam Chun, Yang Gu Lee, Woong Shick Ahn

Pages: 1675-1682 Published online on: 28 January 2015
Article

Emodin attenuates radioresistance induced by hypoxia in HepG2 cells via the enhancement of PARP1 cleavage and inhibition of JMJD2B

Sang Youn Hwang, Kyu Heo, Joon Seok Kim, Jung Woo Im, Sun Mi Lee, Mong Cho, Dae Hwan Kang, Jeong Heo, Jun Woo Lee, Cheol Won Choi, Kwangmo Yang

Pages: 1691-1698 Published online on: 21 January 2015
Article

BRD4 promotes pancreatic ductal adenocarcinoma cell proliferation and enhances gemcitabine resistance

Yong-Hui Wang, Ya-Na Sui, Kai Yan, Li-Shan Wang, Fei Wang, Jia-Hua Zhou

Pages: 1699-1706 Published online on: 30 January 2015
Article

MicroRNA-182 inhibits proliferation through targeting oncogenic ANUBL1 in gastric cancer

Lin Tang, Feng Chen, Er-Jun Pang, Zhi-Qi Zhang, Bing-Wei Jin, Wei-Feng Dong

Pages: 1707-1716 Published online on: 12 February 2015
Article

EGR1 regulates radiation-induced apoptosis in head and neck squamous cell carcinoma

Tae Mi Yoon, Sun-Ae Kim, Dong Hoon Lee, Joon Kyoo Lee, Young-Lan Park, Kyung-Hwa Lee, Ik-Joo Chung, Young-Eun Joo, Sang Chul Lim

Pages: 1717-1722 Published online on: 22 January 2015
Article

Inhibition of c-Myc by let-7b mimic reverses mutidrug resistance in gastric cancer cells

Xiaojun Yang, Hui Cai, Yuhe Liang, Lin Chen, Xiangdong Wang, Ruohuang Si, Kunpeng Qu, Zebin Jiang, Bingqiang Ma, Changfeng Miao, Jing Li, Bin Wang, Peng Gao

Pages: 1723-1730 Published online on: 28 January 2015
Article

Violacein anticancer activity is enhanced under hypoxia

Saeed M. Hashimi, Tiefeng Xu, Ming Q. Wei

Pages: 1731-1736 Published online on: 04 February 2015
Article

Blockage of PTPRJ promotes cell growth and resistance to 5-FU through activation of JAK1/STAT3 in the cervical carcinoma cell line C33A

Chun-Mei Yan, Ying-Ling Zhao, Hong-Yi Cai, Guo-Ying Miao, Wen Ma

Pages: 1737-1744 Published online on: 29 January 2015
Article

OCT4 pseudogene 5 upregulates OCT4 expression to promote proliferation by competing with miR-145 in endometrial carcinoma

Mingzhu Bai, Mu Yuan, Hong Liao, Jiazhou Chen, Binying Xie, Dong Yan, Xiaowei Xi, Xianming Xu, Zhenbo Zhang, Youji Feng

Pages: 1745-1752 Published online on: 29 January 2015
Article

Capecitabine metronomic chemotherapy inhibits the proliferation of gastric cancer cells through anti-angiogenesis

Fei Yuan, Hailong Shi, Jun Ji, Qu Cai, Xuehua Chen, Yingyan Yu, Bingya Liu, Zhenggang Zhu, Jun Zhang

Pages: 1753-1762 Published online on: 29 January 2015
Article

Niclosamide inhibits the proliferation of human osteosarcoma cell lines by inducing apoptosis and cell cycle arrest

Zonghuan Li, Yifeng Yu, Shaoxing Sun, Baiwen Qi, Weiyang Wang, Aixi Yu

Pages: 1763-1768 Published online on: 29 January 2015
Article

Geranylgeranylacetone suppresses colitis‑related mouse colon carcinogenesis

Takuya Inoue, Naoki Yorifuji, Munetaka Iguchi, Kaori Fujiwara, Kazuki Kakimoto, Sadaharu Nouda, Toshihiko Okada, Ken Kawakami, Yosuke Abe, Toshihisa Takeuchi, Kazuhide Higuchi

Pages: 1769-1774 Published online on: 10 February 2015
Article

Berberine induces FasL-related apoptosis through p38 activation in KB human oral cancer cells

Jae-Sung Kim, Dahye Oh, Min-Ji Yim, Jin-Ju  Park, Kyeong-Rok Kang, In-A  Cho, Sung-Min  Moon, Ji-Su  Oh, Jae-Seek You, Chun Sung Kim, Do  Kyung Kim, Sook‑Young Lee, Gyeong-Je Lee, Hee-Jeong Im, Su-Gwan Kim

Pages: 1775-1782 Published online on: 29 January 2015
Article

Asporin participates in gastric cancer cell growth and migration by influencing EGF receptor signaling

Qian Ding, Mei Zhang, Can Liu

Pages: 1783-1790 Published online on: 09 February 2015
Article

Adenovirus-mediated LRIG1 expression enhances the chemosensitivity of bladder cancer cells to cisplatin

Zejun Yan, Junhui Jiang, Fan Li, Weiming Yang, Guohai Xie, Cheng Zhou, Shujie Xia, Yue Cheng

Pages: 1791-1798 Published online on: 16 February 2015
Article

Ubiquilin 2 enhances osteosarcoma progression through resistance to hypoxic stress

Shinji Tsukamoto, Keiji Shimada, Kanya Honoki, Akira Kido, Manabu Akahane, Yasuhito Tanaka, Noboru Konishi

Pages: 1799-1806 Published online on: 09 February 2015
Article

Overexpression of Tiam1 promotes the progression of laryngeal squamous cell carcinoma

Shuang Wang, Shisheng Li, Qinglai Tang, Shu Yang, Shuhui Wang, Jiajia Liu, Mi Yang, Xinming Yang

Pages: 1807-1814 Published online on: 05 February 2015
Article

Recombinant nematode anticoagulant protein c2 inhibits cell invasion by decreasing uPA expression in NSCLC cells

Yu Tong, Jun Yue, Meng Mao, Qingqing Liu, Jing Zhou, Jiyun Yang

Pages: 1815-1822 Published online on: 10 February 2015
Article

Induction and mechanism of HeLa cell apoptosis by 9-oxo‑10, 11-dehydroageraphorone from Eupatorium adenophorum

Fei Liao, Yanchun Hu, Lei Wu, Hui Tan, Biao Luo, Yajun He, Yan Qiao, Quan Mo, Ya Wang, Zhicai Zuo, Junliang Deng, Yahui Wei

Pages: 1823-1827 Published online on: 02 February 2015
Article

Effects of PTEN on the proliferation and apoptosis of colorectal cancer cells via the phosphoinositol-3-kinase/Akt pathway

Yan Sun, Hua Tian, Lin Wang

Pages: 1828-1836 Published online on: 16 February 2015
Article

Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer

Yoshinori Imamura, Toru Mukohara, Yohei Shimono, Yohei Funakoshi, Naoko Chayahara, Masanori Toyoda, Naomi Kiyota, Shintaro Takao, Seishi Kono, Tetsuya Nakatsura, Hironobu Minami

Pages: 1837-1843 Published online on: 29 January 2015
Article

C5aR is frequently expressed in metastatic renal cell carcinoma and plays a crucial role in cell invasion via the ERK and PI3 kinase pathways

Yoshihiro Maeda, Yoshiaki Kawano, Yoshihiro Wada, Junji Yatsuda, Takanobu Motoshima, Yoji Murakami, Ken Kikuchi, Takahisa Imamura, Masatoshi Eto

Pages: 1844-1850 Published online on: 13 February 2015
Article

Downregulation of cathepsin L suppresses cancer invasion and migration by inhibiting transforming growth factor‑β‑mediated epithelial‑mesenchymal transition

Qingqing Zhang, Meiling Han, Wenjuan Wang, Yunzhen Song, Gang Chen, Zhong Wang, Zhongqin Liang

Pages: 1851-1859 Published online on: 27 January 2015
Article

AURKA upregulation plays a role in fibroblast-reduced gefitinib sensitivity in the NSCLC cell line HCC827

Jia Chen, Huiqi Lu, Wang Zhou, Huabin Yin, Lishuang Zhu, Chang Liu, Pengfei Zhang, Huimin Hu, Yili Yang, Huanxing Han

Pages: 1860-1866 Published online on: 29 January 2015
Article

Cucurbitacin I inhibits cell migration and invasion and enhances chemosensitivity in colon cancer

Junmin Song, Hongxiang Liu, Zhen Li, Chao Yang, Chaojie Wang

Pages: 1867-1871 Published online on: 26 January 2015
Article

STAT3 cooperates with Twist to mediate epithelial-mesenchymal transition in human hepatocellular carcinoma cells

Chuanhai Zhang, Fenglin Guo, Geliang Xu, Jie Ma, Feng Shao

Pages: 1872-1882 Published online on: 04 February 2015
Article

HES 1 is essential for chemoresistance induced by stellate cells and is associated with poor prognosis in pancreatic cancer

Feng Cao, Jia Li, Haichen Sun, Shuang Liu, Yeqing Cui, Fei Li

Pages: 1883-1889 Published online on: 09 February 2015
Article

Apicidin inhibits cell growth by downregulating IGF-1R in salivary mucoepidermoid carcinoma cells

Mee-Young Ahn, Ji-Wee Ahn, Hyung-Sik Kim, Jun Lee, Jung-Hoon Yoon

Pages: 1899-1907 Published online on: 02 February 2015
Article

Protein tyrosine phosphatase receptor type O expression in the tumor niche correlates with reduced tumor growth, angiogenesis, circulating tumor cells and metastasis of breast cancer

Zhao Liu, Jiajie Hou, Lidong Ren, Jing He, Beicheng Sun, Lu-Zhe Sun, Shui Wang

Pages: 1908-1914 Published online on: 29 January 2015
Article

N,N'-di-(m-methylphenyi)-3,6-dimethyl-1,4-dihydro-1,2,4,5-tetrazine-1,4-dicarboamide (ZGDHu-1) suppresses the proliferation of PANC-1 pancreatic cancer cells via apoptosis and G2/M cell cycle arrest

Su-Feng Chen, Jun Xia, Ya-Ping Lv, Jin-Lin Liu, Wan-Xiang Li, Xi-Ping Yu, Wei-Xiao Hu, Yong-Lie Zhou

Pages: 1915-1921 Published online on: 16 February 2015
Article

Pien Tze Huang inhibits liver metastasis by targeting TGF-β signaling in an orthotopic model of colorectal cancer

Wei Lin, Qunchuan Zhuang, Liangpu Zheng, Zhiyun Cao, Aling Shen, Qiongyu Li, Caixuan Fu, Jianyu Feng, Jun Peng

Pages: 1922-1928 Published online on: 05 February 2015
Article

GPER in CAFs regulates hypoxia-driven breast cancer invasion in a CTGF-dependent manner

Juan Ren, Hui Guo, Huili Wu, Tao Tian, Danfeng Dong, Yuelang Zhang, Yanxia Sui, Yong Zhang, Dongli Zhao, Shufeng Wang, Zongfang Li, Xiaozhi Zhang, Rui Liu, Jianshneg Qian, Hongxia Wei, Wenjun Jiang, Ya Liu, Yi Li

Pages: 1929-1937 Published online on: 03 February 2015
Article

Angiomotin promotes breast cancer cell proliferation and invasion

Meng Lv, Meiling Lv, Ling Chen, Tianjie Qin, Xiao Zhang, Peijun Liu, Jin Yang

Pages: 1938-1946 Published online on: 03 February 2015
Article
Article

Decreased expression of SCUBE2 is associated with progression and prognosis in colorectal cancer

Qi Song, Chuanwei Li, Xiaodong Feng, Ailian Yu, Huamei Tang, Zhihai Peng, Xuechun Wang

Pages: 1956-1964 Published online on: 09 February 2015
Article

OY-TES-1 may regulate the malignant behavior of liver cancer via NANOG, CD9, CCND2 and CDCA3: A bioinformatic analysis combine with RNAi and oligonucleotide microarray

Qiping Hu, Jun Fu, Bin Luo, Miao Huang, Wenwen Guo, Yongda Lin, Xiaoxun Xie, Shaowen Xiao

Pages: 1965-1975 Published online on: 10 February 2015
Article

(-)-Epigallocatechin-3-gallate reverses the expression of various tumor-suppressor genes by inhibiting DNA methyltransferases and histone deacetylases in human cervical cancer cells

Munawwar Ali Khan, Arif Hussain, Madhumitha Kedhari Sundaram, Usama Alalami, Dian Gunasekera, Laveena Ramesh, Amina Hamza, Uzma Quraishi

Pages: 1976-1984 Published online on: 13 February 2015
Article

Cross-platform meta-analysis of multiple gene expression profiles identifies novel expression signatures in acquired anthracycline-resistant breast cancer

Young Seok Lee, Seung Won Ryu, Se Jong Bae, Tae Hwan Park, Kang Kwon, Yun Hee Noh, Sung Young Kim

Pages: 1985-1993 Published online on: 17 February 2015
Article

Synergistic anti-proliferative effect of metformin and sorafenib on growth of anaplastic thyroid cancer cells and their stem cells

Guofang Chen, Diana Nicula, Kostja Renko, Michael Derwahl

Pages: 1994-2000 Published online on: 16 February 2015
Article

Cytokinesis failure and successful multipolar mitoses drive aneuploidy in glioblastoma cells

Sergej Telentschak, Mark Soliwoda, Klaus Nohroudi, Klaus Addicks, Franz-Josef Klinz

Pages: 2001-2008 Published online on: 27 January 2015
Article

Cytotoxic and radiosensitizing effects of FAK targeting in human glioblastoma cells in vitro

Katja Storch, Andre Sagerer, Nils Cordes

Pages: 2009-2016 Published online on: 27 January 2015
Article

Assessment of MLL methyltransferase gene expression in larynx carcinoma

David Livingstone Alves Figueiredo, Doralina do Amaral Rabello, Dalila Luciola Zanette, Fabiano Pinto Saggioro, Rui Celso Martins Mamede, Marco Antonio Zago, Wilson Araújo da Silva, Felipe Saldanha-Araújo, Fabio Pittella Silva

Pages: 2017-2022 Published online on: 28 January 2015
Article

Increased chemoresistance to paclitaxel in the MCF10AT series of human breast epithelial cancer cells

Soo-Jeong Lim, Hyeon Gyeom Choi, Chae Kyung Jeon, So Hee Kim

Pages: 2023-2030 Published online on: 02 February 2015
Article

3,3'-Diindolylmethane potentiates paclitaxel-induced antitumor effects on gastric cancer cells through the Akt/FOXM1 signaling cascade

Hua Jin, Man Hee Park, Soo Mi Kim

Pages: 2031-2036 Published online on: 28 January 2015
Article

Krüppel-like factor 10 null mice exhibit lower tumor incidence and suppressed cellular proliferation activity following chemically induced liver tumorigenesis

Seung-Ho Heo, Eui-Suk Jeong, Kyoung-Sun Lee, Jin‑Hee Seo, Woon-Kyu Lee, Yang-Kyu Choi

Pages: 2037-2044 Published online on: 13 February 2015
Article

Ara-C increases gastric cancer cell invasion by upregulating CD-147-MMP-2/MMP‑9 via the ERK signaling pathway

Guang-Lin Yang, Hai-Rong Tao, Han-Wei Wang, Yun Sun, Li-Di Zhang, Chao Zhang, Wei He, Mang-Hua Xu, Jiang-Min Zhao, Feng-Hou Gao

Pages: 2045-2051 Published online on: 23 January 2015
Article

Wnt7A is a putative prognostic and chemosensitivity marker in human malignant pleural mesothelioma

Tomomi Hirata, Qingfeng Zheng, Zhao Chen, Hiroyasu Kinoshita, Junichi Okamoto, Johannes Kratz, Hui Li, Natalie Lui, Hanh Do, Tiffany Cheng, Hsin-Hui Katty Tseng, Kiyoshi Koizumi, Kazuo Shimizu, Hai‑Meng Zhou, David Jablons, Biao He

Pages: 2052-2060 Published online on: 29 January 2015
Article

miR-375 inhibits cell growth and correlates with clinical outcomes in tongue squamous cell carcinoma

Lingfei Jia, Yiping Huang, Yunfei Zheng, Mingyue Lyu, Chunan Zhang, Zhen Meng, Yehua Gan, Guangyan Yu

Pages: 2061-2071 Published online on: 28 January 2015
Article

Selective anticancer activity of hirsutine against HER2‑positive breast cancer cells by inducing DNA damage

Chenghua Lou, Satoru Yokoyama, Ikuo Saiki, Yoshihiro Hayakawa

Pages: 2072-2076 Published online on: 12 February 2015
Article

Baicalein suppresses 17-β-estradiol-induced migration, adhesion and invasion of breast cancer cells via the G protein-coupled receptor 30 signaling pathway

Dandan Shang, Zheng Li, Zhuxia Zhu, Huamei Chen, Lujun Zhao, Xudong Wang, Yan Chen

Pages: 2077-2085 Published online on: 05 February 2015
Article

PGC-1α is responsible for survival of multiple myeloma cells under hyperglycemia and chemotherapy

Wen Yu, Dedong Cao, Hao Zhou, Yu Hu, Tao Guo

Pages: 2086-2092 Published online on: 17 February 2015
Correction Open Access

[Corrigendum] microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is associated with liver metastasis in colorectal cancer

Yujun Zhang, Xiangjun He, Yulan Liu, Yingjiang Ye, Hui Zhang, Peiying He, Qi Zhang, Lingyi Dong, Yujing Liu, Jianqiang Dong

Pages: 2093-2093 Published online on: 30 January 2015
Journal Cover

April-2015
Volume 33 Issue 4

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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