|
1
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics, 2012. CA Cancer J Clin. 62:10–29. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
You WC, Jin F, Devesa S, et al: Rapid
increase in colorectal cancer rates in urban Shanghai, 1972–97, in
relation to dietary changes. J Cancer Epidemiol Prev. 7:143–146.
2002.
|
|
3
|
Cerottini JP, Caplin S, Pampallona S and
Givel JC: Prognostic factors in colorectal cancer. Oncol Rep.
6:409–414. 1999.PubMed/NCBI
|
|
4
|
Parsons DW, Wang TL, Samuels Y, et al:
Colorectal cancer: mutations in a signalling pathway. Nature.
436:7922005. View
Article : Google Scholar : PubMed/NCBI
|
|
5
|
Lee JO, Yang H, Georgescu MM, et al:
Crystal structure of the PTEN tumor suppressor: implications for
its phosphoinositide phosphatase activity and membrane association.
Cell. 99:323–334. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Di Cristofano A and Pandolfi PP: The
multiple roles of PTEN in tumor suppression. Cell. 100:387–390.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Cully M, You H, Levine AJ and Mak TW:
Beyond PTEN mutations: the PI3K pathway as an integrator of
multiple inputs during tumorigenesis. Nat Rev Cancer. 6:184–192.
2006. View
Article : Google Scholar : PubMed/NCBI
|
|
8
|
Accili D and Arden KC: FoxOs at the
crossroads of cellular metabolism, differentiation, and
transformation. Cell. 117:421–426. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Greer EL and Brunet A: FOXO transcription
factors at the interface between longevity and tumor suppression.
Oncogene. 24:7410–7425. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Brunet A, Bonni A, Zigmond MJ, et al: Akt
promotes cell survival by phosphorylating and inhibiting a Forkhead
transcription factor. Cell. 96:857–868. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Morson BC: The evolution of colorectal
carcinoma. Clin Radiol. 35:425–431. 1984. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Sherman DW, Ye XY, McSherry C, Parkas V,
Calabrese M and Gatto M: Quality of life of patients with advanced
cancer and acquired immune deficiency syndrome and their family
caregivers. J Palliat Med. 9:948–963. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Zhang SQ: Screening and prevention of
colorectal cancer in Haining County. Dis Colon Rectum. 28:300–304.
1985. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Zhang SQ, Zhu SX and Wu JM: Screening and
prevention of colorectal cancer in Haining county. Chin Med J.
93:843–848. 1980.PubMed/NCBI
|
|
15
|
Stambolic V, Suzuki A, de la Pompa JL, et
al: Negative regulation of PKB/Akt-dependent cell survival by the
tumor suppressor PTEN. Cell. 95:29–39. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Eng C: PTEN: one gene, many syndromes. Hum
Mutat. 22:183–198. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Rustia A, Wierzbicki V, Marrocco L,
Tossini A, Zamponi C and Lista F: Is exon 5 of the PTEN/MMAC1 gene
a prognostic marker in anaplastic glioma? Neurosurg Rev. 24:97–102.
2001. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Cheney IW, Neuteboom ST, Vaillancourt MT,
Ramachandra M and Bookstein R: Adenovirus-mediated gene transfer of
MMAC1/PTEN to glioblastoma cells inhibits S phase entry by the
recruitment of p27Kip1 into cyclin E/CDK2 complexes.
Cancer Res. 59:2318–2323. 1999.PubMed/NCBI
|
|
19
|
Cantley LC and Neel BG: New insights into
tumor suppression: PTEN suppresses tumor formation by restraining
the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci USA.
96:4240–4245. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Burgering BM and Kops GJ: Cell cycle and
death control: long live Forkheads. Trends Biochem Sci. 27:352–360.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Burgering BM and Medema RH: Decisions on
life and death: FOXO Forkhead transcription factors are in command
when PKB/Akt is off duty. J Leukoc Biol. 73:689–701. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Brownawell AM, Kops GJ, Macara IG and
Burgering BM: Inhibition of nuclear import by protein kinase B
(Akt) regulates the subcellular distribution and activity of the
forkhead transcription factor AFX. Mol Cell Biol. 21:3534–3546.
2001. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Shi F and LaPolt PS: Relationship between
FoxO1 protein levels and follicular development, atresia, and
luteinization in the rat ovary. J Endocrinol. 179:195–203. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Brunet A, Kanai F, Stehn J, et al: 14-3-3
transits to the nucleus and participates in dynamic
nucleocytoplasmic transport. J Cell Biol. 156:817–828. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ramaswamy S, Nakamura N, Sansal I,
Bergeron L and Sellers WR: A novel mechanism of gene regulation and
tumor suppression by the transcription factor FKHR. Cancer Cell.
2:81–91. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Medema RH, Kops GJ, Bos JL and Burgering
BM: AFX-like Forkhead transcription factors mediate cell-cycle
regulation by Ras and PKB through p27kip1. Nature.
404:782–787. 2000. View
Article : Google Scholar : PubMed/NCBI
|
|
27
|
Kops GJ, Medema RH, Glassford J, et al:
Control of cell cycle exit and entry by protein kinase B-regulated
forkhead transcription factors. Mol Cell Biol. 22:2025–2036. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Schmidt M, Fernandez de Mattos S, van der
Horst A, et al: Cell cycle inhibition by FoxO forkhead
transcription factors involves downregulation of cyclin D. Mol Cell
Biol. 22:7842–7852. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Martinez-Gac L, Marques M, Garcia Z,
Campanero MR and Carrera AC: Control of cyclin G2 mRNA expression
by forkhead transcription factors: novel mechanism for cell cycle
control by phosphoinositide 3-kinase and forkhead. Mol Cell Biol.
24:2181–2189. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Ramaswamy S, Nakamura N, Vazquez F, et al:
Regulation of G1 progression by the PTEN tumor suppressor protein
is linked to inhibition of the phosphatidylinositol 3-kinase/Akt
pathway. Proc Natl Acad Sci USA. 96:2110–2115. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Di Cristofano A, De Acetis M, Koff A,
Cordon-Cardo C and Pandolfi PP: Pten and p27KIP1
cooperate in prostate cancer tumor suppression in the mouse. Nat
Genet. 27:222–224. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zhu X, Kwon CH, Schlosshauer PW, Ellenson
LH and Baker SJ: PTEN induces G(1) cell cycle arrest and decreases
cyclin D3 levels in endometrial carcinoma cells. Cancer Res.
61:4569–4575. 2001.PubMed/NCBI
|
|
33
|
Weng LP, Brown JL and Eng C: PTEN
coordinates G(1) arrest by down-regulating cyclin D1 via its
protein phosphatase activity and up-regulating p27 via its lipid
phosphatase activity in a breast cancer model. Hum Mol Genet.
10:599–604. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wu RC, Li X and Schonthal AH:
Transcriptional activation of p21WAF1 by PTEN/MMAC1 tumor
suppressor. Mol Cell Biochem. 203:59–71. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Romashkova JA and Makarov SS: NF-kappaB is
a target of AKT in anti-apoptotic PDGF signalling. Nature.
401:86–90. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
36
|
Gustin JA, Maehama T, Dixon JE and Donner
DB: The PTEN tumor suppressor protein inhibits tumor necrosis
factor-induced nuclear factor kappa B activity. J Biol Chem.
276:27740–27744. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Yuan XJ and Whang YE: PTEN sensitizes
prostate cancer cells to death receptor-mediated and drug-induced
apoptosis through a FADD-dependent pathway. Oncogene. 21:319–327.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Huang H, Cheville JC, Pan Y, Roche PC,
Schmidt LJ and Tindall DJ: PTEN induces chemosensitivity in
PTEN-mutated prostate cancer cells by suppression of Bcl-2
expression. J Biol Chem. 276:38830–38836. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Mayo LD, Dixon JE, Durden DL, Tonks NK and
Donner DB: PTEN protects p53 from Mdm2 and sensitizes cancer cells
to chemotherapy. J Biol Chem. 277:5484–5489. 2002. View Article : Google Scholar
|
|
40
|
Stambolic V, MacPherson D, Sas D, et al:
Regulation of PTEN transcription by p53. Mol Cell. 8:317–325. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Reagan-Shaw S and Ahmad N: RNA
interference-mediated depletion of phosphoinositide 3-kinase
activates forkhead box class O transcription factors and induces
cell cycle arrest and apoptosis in breast carcinoma cells. Cancer
Res. 66:1062–1069. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Carter JH, Douglass LE, Deddens JA, et al:
Pak-1 expression increases with progression of colorectal
carcinomas to metastasis. Clin Cancer Res. 10:3448–3456. 2004.
View Article : Google Scholar : PubMed/NCBI
|
