|
1
|
Koelle MR: A new family of G-protein
regulators - the RGS proteins. Curr Opin Cell Biol. 9:143–147.
1997. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Willars GB: Mammalian RGS proteins:
Multifunctional regulators of cellular signalling. Semin Cell Dev
Biol. 17:363–376. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Bansal G, Druey KM and Xie Z: R4 RGS
proteins: Regulation of G-protein signaling and beyond. Pharmacol
Ther. 116:473–495. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Bondjers C, Kalén M, Hellström M, Scheidl
SJ, Abramsson A, Renner O, Lindahl P, Cho H, Kehrl J and Betsholtz
C: Transcription profiling of platelet-derived growth
factor-B-deficient mouse embryos identifies RGS5 as a novel marker
for pericytes and vascular smooth muscle cells. Am J Pathol.
162:721–729. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Cho H, Kozasa T, Bondjers C, Betsholtz C
and Kehrl JH: Pericyte-specific expression of Rgs5: Implications
for PDGF and EDG receptor signaling during vascular maturation.
FASEB J. 17:440–442. 2003.PubMed/NCBI
|
|
6
|
Seki N, Sugano S, Suzuki Y, Nakagawara A,
Ohira M, Muramatsu M, Saito T and Hori T: Isolation, tissue
expression, and chromosomal assignment of human RGS5, a novel
G-protein signaling regulator gene. J Hum Genet. 43:202–205. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Li H, He C, Feng J, Zhang Y, Tang Q, Bian
Z, Bai X, Zhou H, Jiang H, Heximer SP, et al: Regulator of G
protein signaling 5 protects against cardiac hypertrophy and
fibrosis during biomechanical stress of pressure overload. Proc
Natl Acad Sci USA. 107:13818–13823. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Cho H, Park C, Hwang IY, Han SB, Schimel
D, Despres D and Kehrl JH: Rgs5 targeting leads to chronic low
blood pressure and a lean body habitus. Mol Cell Biol.
28:2590–2597. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Li J, Adams LD, Wang X, Pabon L, Schwartz
SM, Sane DC and Geary RL: Regulator of G protein signaling 5 marks
peripheral arterial smooth muscle cells and is downregulated in
atherosclerotic plaque. J Vasc Surg. 40:519–528. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Takata Y, Liu J, Yin F, Collins AR, Lyon
CJ, Lee CH, Atkins AR, Downes M, Barish GD, Evans RM, et al:
PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin
II-accelerated atherosclerosis. Proc Natl Acad Sci USA.
105:4277–4282. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Deng W, Wang X, Xiao J, Chen K, Zhou H,
Shen D, Li H and Tang Q: Loss of regulator of G protein signaling 5
exacerbates obesity, hepatic steatosis, inflammation and insulin
resistance. PLoS One. 7:e302562012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Yang Z, Balenga N, Cooper PR, Damera G,
Edwards R, Brightling CE, Panettieri RA Jr and Druey KM: Regulator
of G-protein signaling-5 inhibits bronchial smooth muscle
contraction in severe asthma. Am J Respir Cell Mol Biol.
46:823–832. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Bell SE, Mavila A, Salazar R, Bayless KJ,
Kanagala S, Maxwell SA and Davis GE: Differential gene expression
during capillary morphogenesis in 3D collagen matrices: Regulated
expression of genes involved in basement membrane matrix assembly,
cell cycle progression, cellular differentiation and G-protein
signaling. J Cell Sci. 114:2755–2773. 2001.PubMed/NCBI
|
|
14
|
Berger M, Bergers G, Arnold B, Hämmerling
GJ and Ganss R: Regulator of G-protein signaling-5 induction in
pericytes coincides with active vessel remodeling during
neovascularization. Blood. 105:1094–1101. 2005. View Article : Google Scholar
|
|
15
|
Arnold C, Feldner A, Pfisterer L, Hödebeck
M, Troidl K, Genové G, Wieland T, Hecker M and Korff T: RGS5
promotes arterial growth during arteriogenesis. EMBO Mol Med.
6:1075–1089. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Furuya M, Nishiyama M, Kimura S, Suyama T,
Naya Y, Ito H, Nikaido T and Ishikura H: Expression of regulator of
G protein signalling protein 5 (RGS5) in the tumour vasculature of
human renal cell carcinoma. J Pathol. 203:551–558. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Chen X, Higgins J, Cheung ST, Li R, Mason
V, Montgomery K, Fan ST, van de Rijn M and So S: Novel endothelial
cell markers in hepatocellular carcinoma. Mod Pathol. 17:1198–1210.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Silini A, Ghilardi C, Figini S, Sangalli
F, Fruscio R, Dahse R, Pedley RB, Giavazzi R and Bani M: Regulator
of G-protein signaling 5 (RGS5) protein: A novel marker of cancer
vasculature elicited and sustained by the tumor’s proangiogenic
microenvironment. Cell Mol Life Sci. 69:1167–1178. 2012. View Article : Google Scholar :
|
|
19
|
Wang JH, Huang WS, Hu CR, Guan XX, Zhou HB
and Chen LB: Relationship between RGS5 expression and
differentiation and angiogenesis of gastric carcinoma. World J
Gastroenterol. 16:5642–5646. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Koh J, Dar M, Untch BR, Dixit D, Shi Y,
Yang Z, Adam MA, Dressman H, Wang X, Gesty-Palmer D, et al:
Regulator of G protein signaling 5 is highly expressed in
parathyroid tumors and inhibits signaling by the calcium-sensing
receptor. Mol Endocrinol. 25:867–876. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Huang G, Song H, Wang R, Han X and Chen L:
The relationship between RGS5 expression and cancer differentiation
and metastasis in non-small cell lung cancer. J Surg Oncol.
105:420–424. 2012. View Article : Google Scholar
|
|
22
|
Yang X, Cai W, Xu Z, Chen J, Li C, Liu S,
Yang Z, Pan Q, Li M, Ma J, et al: High efficacy and minimal peptide
required for the anti-angiogenic and anti-hepatocarcinoma
activities of plasminogen K5. J Cell Mol Med. 14:2519–2530. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Xu Z, Fang S, Zuo Y, Zhang Y, Cheng R,
Wang Q, Yang Z, Cai W, Ma J, Yang X, et al: Combination of pigment
epithelium-derived factor with radiotherapy enhances the antitumor
effects on nasopharyngeal carcinoma by downregulating vascular
endothelial growth factor expression and angiogenesis. Cancer Sci.
102:1789–1798. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Fei P and El-Deiry WS: P53 and radiation
responses. Oncogene. 22:5774–5783. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Venkatakrishnan AJ, Deupi X, Lebon G, Tate
CG, Schertler GF and Babu MM: Molecular signatures of
G-protein-coupled receptors. Nature. 494:185–194. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Karnik SS, Gogonea C, Patil S, Saad Y and
Takezako T: Activation of G-protein-coupled receptors: A common
molecular mechanism. Trends Endocrinol Metab. 14:431–437. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
O’Callaghan K, Kuliopulos A and Covic L:
Turning receptors on and off with intracellular pepducins: New
insights into G-protein-coupled receptor drug development. J Biol
Chem. 287:12787–12796. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Roman DL and Traynor JR: Regulators of G
protein signaling (RGS) proteins as drug targets: Modulating
G-protein-coupled receptor (GPCR) signal transduction. J Med Chem.
54:7433–7440. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Dorsam RT and Gutkind JS:
G-protein-coupled receptors and cancer. Nat Rev Cancer. 7:79–94.
2007. View
Article : Google Scholar : PubMed/NCBI
|
|
30
|
Nishiura H, Nonaka H, Revollo IS, Semba U,
Li Y, Ota Y, Irie A, Harada K, Kehrl JH and Yamamoto T: Pro- and
anti-apoptotic dual functions of the C5a receptor: Involvement of
regulator of G protein signaling 3 and extracellular
signal-regulated kinase. Lab Invest. 89:676–694. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Liang G, Bansal G, Xie Z and Druey KM:
RGS16 inhibits breast cancer cell growth by mitigating
phosphatidylinositol 3-kinase signaling. J Biol Chem.
284:21719–21727. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Altman MK, Nguyen DT, Patel SB, Fambrough
JM, Beedle AM, Hardman WJ and Murph MM: Regulator of G-protein
signaling 5 reduces HeyA8 ovarian cancer cell proliferation and
extends survival in a murine tumor model. Biochem Res Int.
2012:5184372012. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Maity B, Yang J, Huang J, Askeland RW,
Bera S and Fisher RA: Regulator of G protein signaling 6 (RGS6)
induces apoptosis via a mitochondrial-dependent pathway not
involving its GTPase-activating protein activity. J Biol Chem.
286:1409–1419. 2011. View Article : Google Scholar :
|
|
34
|
Jin Y, An X, Ye Z, Cully B, Wu J and Li J:
RGS5, a hypoxia-inducible apoptotic stimulator in endothelial
cells. J Biol Chem. 284:23436–23443. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Czabotar PE, Lessene G, Strasser A and
Adams JM: Control of apoptosis by the BCL-2 protein family:
Implications for physiology and therapy. Nat Rev Mol Cell Biol.
15:49–63. 2014. View Article : Google Scholar
|
|
36
|
Mu XM, Shi W, Sun LX, Li H, Wang YR, Jiang
ZZ and Zhang LY: Pristimerin inhibits breast cancer cell migration
by up-regulating regulator of G protein signaling 4 expression.
Asian Pac J Cancer Prev. 13:1097–1104. 2012. View Article : Google Scholar
|
|
37
|
Xie Y, Wolff DW, Wei T, Wang B, Deng C,
Kirui JK, Jiang H, Qin J, Abel PW and Tu Y: Breast cancer migration
and invasion depend on proteasome degradation of regulator of
G-protein signaling 4. Cancer Res. 69:5743–5751. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Schofield AV and Bernard O: Rho-associated
coiled-coil kinase (ROCK) signaling and disease. Crit Rev Biochem
Mol Biol. 48:301–316. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Rane CK and Minden A: P21 activated
kinases: Structure, regulation, and functions. Small GTPases.
5:52014. View Article : Google Scholar
|
|
40
|
Luanpitpong S, Talbott SJ, Rojanasakul Y,
Nimmannit U, Pongrakhananon V, Wang L and Chanvorachote P:
Regulation of lung cancer cell migration and invasion by reactive
oxygen species and caveolin-1. J Biol Chem. 285:38832–38840. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Hooks SB, Callihan P, Altman MK, Hurst JH,
Ali MW and Murph MM: Regulators of G-Protein signaling RGS10 and
RGS17 regulate chemoresistance in ovarian cancer cells. Mol Cancer.
9:2892010. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Huang J, Yang J, Maity B, Mayuzumi D and
Fisher RA: Regulator of G protein signaling 6 mediates
doxorubicin-induced ATM and p53 activation by a reactive oxygen
species-dependent mechanism. Cancer Res. 71:6310–6319. 2011.
View Article : Google Scholar : PubMed/NCBI
|
