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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2015 Volume 33 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Quercetin in prostate cancer: Chemotherapeutic and chemopreventive effects, mechanisms and clinical application potential (Review)

Feiya Yang, Liming Song, Huiping Wang, Jun Wang, Zhiqing Xu, Nianzeng Xing
Pages: 2659-2668
Published online on: 31 March 2015

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Review

The emerging landscape of circular RNA ciRS-7 in cancer (Review)

Li Peng, Xiao Qing Yuan, Guan Cheng Li
Pages: 2669-2674
Published online on: 08 April 2015

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Article Open Access

HMGA2 expression pattern and TERT mutations in tumors of the vulva

Antonio Agostini, Ioannis Panagopoulos, Hege Kilen Andersen, Lene Elisabeth Johannesen, Ben Davidson, Claes Göran Tropé, Sverre Heim, Francesca Micci
Pages: 2675-2680
Published online on: 30 March 2015

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Article Open Access

Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620 Corrigendum in /or/35/2/1222

Yitao Jia, Suqiao Zhang, Lingling Miao, Jingbao Wang, Zujian Jin, Bin Gu, Zhihui Duan, Zhaolong Zhao, Shunmao Ma, Wenjin Zhang, Zhongxin Li
Pages: 2681-2688
Published online on: 03 April 2015

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Article Open Access

Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells

Aiwei Yao-Borengasser, Behjatolah Monzavi-Karbassi, Rebecca A. Hedges, Lora J. Rogers, Susan A. Kadlubar, Thomas Kieber-Emmons
Pages: 2689-2694
Published online on: 30 March 2015

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Article Open Access

Enhanced antitumor immunity of nanoliposome-encapsulated heat shock protein 70 peptide complex derived from dendritic tumor fusion cells

Yunfei Zhang, Wen Luo, Yucai Wang, Jun Chen, Yunyan Liu, Yong Zhang
Pages: 2695-2702
Published online on: 27 April 2015

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Article Open Access

Interleukin-8: A potent promoter of human lymphatic endothelial cell growth in gastric cancer

Jun Shi, Yong-Jin Li, Bing Yan, Pin-Kang Wei
Pages: 2703-2710
Published online on: 17 April 2015

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Article Open Access

Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells

Kai Jiang, Wei Wang, Xin Jin, Zhaoyang Wang, Zhiwei Ji, Guanmin Meng
Pages: 2711-2718
Published online on: 17 April 2015

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Article Open Access

Eprobe-mediated screening system for somatic mutations in the KRAS locus

Jun Atsumi, Takeshi Hanami, Yasuaki Enokida, Hiroomi Ogawa, Diane Delobel, Yasumasa Mitani, Yasumasa Kimura, Takahiro Soma, Michihira Tagami, Yoshiaki Takase, Tatsuo Ichihara, Izumi Takeyoshi, Kengo Usui, Yoshihide Hayashizaki, Kimihiro Shimizu
Pages: 2719-2727
Published online on: 30 March 2015

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Article Open Access

Screening and preliminary validation of miRNAs with the regulation of hTERT in colorectal cancer

Yu-Zhou Qin, Xue-Cheng Xie, Hai-Zhou Liu, Hao Lai, Hai Qiu, Lian-Ying Ge
Pages: 2728-2736
Published online on: 01 April 2015

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Article Open Access

Orally active αvβ3 integrin inhibitor MK‑0429 reduces melanoma metastasis

Maureen Pickarski, Alexa Gleason, Bohumil Bednar, Le T. Duong
Pages: 2737-2745
Published online on: 09 April 2015

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Article

IL-33-induced JNK pathway activation confers gastric cancer chemotherapy resistance

Xiao-Lei Ye, Ya-Rong Zhao, Guo-Bin Weng, Yi-Chen Chen, Xue-Ni Wei, Jing-Ping Shao, Hui Ji
Pages: 2746-2752
Published online on: 03 April 2015

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Article

miR-203 inhibits arecoline-induced epithelial‑mesenchymal transition by regulating secreted frizzled-related protein 4 and transmembrane-4 L six family member 1 in oral submucous fibrosis

Lian Zheng, Xinchun Jian, Feng Guo, Ning Li, Canhua Jiang, Ping Yin, An-Jie Min, Long Huang
Pages: 2753-2760
Published online on: 09 April 2015

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Article

Purvalanol induces endoplasmic reticulum stress-mediated apoptosis and autophagy in a time-dependent manner in HCT116 colon cancer cells

Ajda Coker-Gürkan, Elif Damla Arisan, Pınar Obakan, Kübra Akalın, Utku Özbey, Narcin Palavan-Unsal
Pages: 2761-2770
Published online on: 21 April 2015

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Article

Altered expression and loss of heterozygosity of the migration and invasion inhibitory protein (MIIP) gene in breast cancer

Fangfang Song, Ling Zhang, Ping Ji, Hong Zheng, Yanrui Zhao, Wei Zhang, Kexin Chen
Pages: 2771-2778
Published online on: 08 April 2015

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Article

SPLUNC1 reduces the inflammatory response of nasopharyngeal carcinoma cells infected with the EB virus by inhibiting the TLR9/NF-κB pathway

Chunlin Ou, Zhenqiang Sun, Han Zhang, Wei Xiong, Jian Ma, Ming Zhou, Jianhong Lu, Zhaoyang Zeng, Xiang Bo, Pan Chen, Guiyuan Li, Xiayu Li, Xiaoling Li
Pages: 2779-2788
Published online on: 17 April 2015

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Article

Hypoxia-induced miR-181b enhances angiogenesis of retinoblastoma cells by targeting PDCD10 and GATA6

Xiaofang Xu, Shengfang Ge, Renbing Jia, Yixiong Zhou, Xin Song, He Zhang, Xianqun Fan
Pages: 2789-2796
Published online on: 07 April 2015

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Article

Establishment and characterization of a cell line from human adenoid cystic carcinoma of the lacrimal glands and a nude mouse transplantable model

Tingting Lin, Limin Zhu, Beiqing Zhou, Lianfeng Xie, Jianmei Lv, Lijie Dong, Yanjin He
Pages: 2797-2806
Published online on: 24 April 2015

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Article

Silencing of the TPM1 gene induces radioresistance of glioma U251 cells

Hua-Qing Du, Ying Wang, Yao Jiang, Chen-Han Wang, Tao Zhou, Hong-Yi Liu, Hong Xiao
Pages: 2807-2814
Published online on: 08 April 2015

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Article

Mangiferin regulates proliferation and apoptosis in glioma cells by induction of microRNA-15b and inhibition of MMP-9 expression

Jinsong Xiao, Li Liu, Zian Zhong, Cheng Xiao, Junjian Zhang
Pages: 2815-2820
Published online on: 21 April 2015

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Article

Knockdown of microRNA-1323 restores sensitivity to radiation by suppression of PRKDC activity in radiation-resistant lung cancer cells

Yong Li, Wei Han, Ting-Ting Ni, Liang Lu, Min Huang, Yu Zhang, Hui Cao, Han-Qun Zhang, Wen Luo, Hang Li
Pages: 2821-2828
Published online on: 30 March 2015

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Article

Icariin regulates the proliferation and apoptosis of human ovarian cancer cells through microRNA-21 by targeting PTEN, RECK and Bcl-2

Jingwei Li, Kailei Jiang, Fujie Zhao
Pages: 2829-2836
Published online on: 01 April 2015

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Article

Recombinant Salmonella-based CEACAM6 and 4-1BBL vaccine enhances T-cell immunity and inhibits the development of colorectal cancer in rats: In vivo effects of vaccine containing 4-1BBL and CEACAM6

Chunhui Jin, Yingying Liu, Jianhong Zhu, Tingting Xia, Baonan Zhang, Yajun Fei, Bo Ma, Jianxin Ye, Weichang Chen
Pages: 2837-2844
Published online on: 07 April 2015

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Article

Aberrant alternative splicing pattern of ADAR2 downregulates adenosine-to-inosine editing in glioma

Zhaohui Li, Yu Tian, Nan Tian, Xingli Zhao, Chao Du, Liang Han, Haishan Zhang
Pages: 2845-2852
Published online on: 08 April 2015

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Article

MicroRNA-18a enhances the radiosensitivity of cervical cancer cells by promoting radiation-induced apoptosis Retraction in /10.3892/or.2025.9023

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Pages: 2853-2862
Published online on: 27 April 2015

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Article

Differential expression of serum microRNAs in cirrhosis that evolve into hepatocellular carcinoma related to hepatitis B virus

Youwen Tan, Bin Lin, Yun Ye, Danfeng Wen, Li Chen, Xinbei Zhou
Pages: 2863-2870
Published online on: 24 April 2015

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Article

Ginkgo biloba extract enhances chemotherapy sensitivity and reverses chemoresistance through suppression of the KSR1-mediated ERK1/2 pathway in gastric cancer cells

Shi-Quan Liu, Chun-Yan Xu, Meng-Bin Qin, Lin Tan, Chun-Feng Zhuge, Ye-Bo Mao, Ming-Yu Lai, Jie-An Huang
Pages: 2871-2882
Published online on: 24 April 2015

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Article

Patient-specific characterization of the invasiveness and proliferation of low-grade gliomas using serial MR imaging and a mathematical model of tumor growth

Leith Hathout, Benjamin M. Ellingson, Timothy F. Cloughesy, Whitney B. Pope
Pages: 2883-2888
Published online on: 27 April 2015

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Article

miR-128-3p suppresses hepatocellular carcinoma proliferation by regulating PIK3R1 and is correlated with the prognosis of HCC patients

Chao-Yuan Huang, Xin-Ping Huang, Ji-Ye Zhu, Zhi-Gang Chen, Xian-Jian Li, Xue-Hui Zhang, Shan Huang, Jian-Bo He, Fang Lian, Yin-Nong Zhao, Guo-Bin Wu
Pages: 2889-2898
Published online on: 28 April 2015

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Article

Overexpression of the regulator of G-protein signaling 5 reduces the survival rate and enhances the radiation response of human lung cancer cells

Zumin Xu, Yufang Zuo, Jin Wang, Zhonghua Yu, Fang Peng, Yuanyuan Chen, Yong Dong, Xiao Hu, Qichao Zhou, Honglian Ma, Yong Bao, Ming Chen
Pages: 2899-2907
Published online on: 20 April 2015

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Article

The cysteine-rich core domain of REIC/Dkk-3 is critical for its effect on monocyte differentiation and tumor regression

Rie Kinoshita, Masami Watanabe, Peng Huang, Shun-Ai Li, Masakiyo Sakaguchi, Hiromi Kumon, Junichiro Futami
Pages: 2908-2914
Published online on: 30 March 2015

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Article

Urinary microRNA-30a-5p is a potential biomarker for ovarian serous adenocarcinoma

Jun Zhou, Guanghui Gong, Hong Tan, Furong Dai, Xin Zhu, Yile Chen, Junpu Wang, Ying Liu, Puxiang Chen, Xiaoying Wu, Jifang Wen
Pages: 2915-2923
Published online on: 28 April 2015

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Article

Mitochondrial DNA alterations correlate with the pathological status and the immunological ER, PR, HER-2/neu, p53 and Ki-67 expression in breast invasive ductal carcinoma

Chen-Sung Lin, Shi-Chuan Chang, Liang-Hung Ou, Chien-Ming Chen, Sophie Swen‑Wan Hsieh, Yu-Ping Chung, Kuang-Liang King, Shoei-Loong Lin, Yau-Huei Wei
Pages: 2924-2934
Published online on: 31 March 2015

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Article

Role of chemokine CX3CL1 in progression of multiple myeloma via CX3CR1 in bone microenvironments

Akinori Wada, Aya Ito, Hirofumi Iitsuka, Koichi Tsuneyama, Takayoshi Miyazono, Jun Murakami, Naotoshi Shibahara, Hiroaki Sakurai, Ikuo Saiki, Takashi Nakayama, Osamu Yoshie, Keiichi Koizumi, Toshiro Sugiyama
Pages: 2935-2939
Published online on: 28 April 2015

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Article

Tetraarsenic hexoxide demonstrates anticancer activity at least in part through suppression of NF-κB activity in SW620 human colon cancer cells

Won Sup Lee, Jeong Won Yun, Arulkumar Nagappan, Hyeon Soo Park, Jing Nan Lu, Hye Jung Kim, Seong-Hwan Chang, Dong Chul Kim, Jeong-Hee Lee, Jin-Myung Jung, Soon Chan Hong, Woo Song Ha, Gonsup Kim
Pages: 2940-2946
Published online on: 31 March 2015

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Article

Sorafenib enhances the antitumor effects of anti-CTLA-4 antibody in a murine cancer model by inhibiting myeloid-derived suppressor cells

Takanobu Motoshima, Yoshihiro Komohara, Hasita Horlad, Ario Takeuchi, Yoshihiro Maeda, Kenichiro Tanoue, Yoshiaki Kawano, Mamoru Harada, Motohiro Takeya, Masatoshi Eto
Pages: 2947-2953
Published online on: 02 April 2015

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Article

Eukaryotic initiation factor 3C silencing inhibits cell proliferation and promotes apoptosis in human glioma

Jinmin Hao, Zhiming Wang, Yaowu Wang, Zhaohui Liang, Xin Zhang, Zongmao Zhao, Baohua Jiao
Pages: 2954-2962
Published online on: 30 March 2015

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Article

Screening of differential microRNA expression in gastric signet ring cell carcinoma and gastric adenocarcinoma and target gene prediction

Jian Chen, Di Sun, Hongjin Chu, Zhaohua Gong, Chenglin Zhang, Benjiao Gong, Yan Li, Ning Li, Lixin Jiang
Pages: 2963-2971
Published online on: 28 April 2015

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Article

Epigallocatechin-3-gallate inhibits nicotine‑induced migration and invasion by the suppression of angiogenesis and epithelial‑mesenchymal transition in non-small cell lung cancer cells Corrigendum in /10.3892/or.2023.8614

Jingli Shi, Fei Liu, Wenzhang Zhang, Xin Liu, Bihua Lin, Xudong Tang
Pages: 2972-2980
Published online on: 31 March 2015

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Article

Versican silencing improves the antitumor efficacy of endostatin by alleviating its induced inflammatory and immunosuppressive changes in the tumor microenvironment

Zi Wang, Zhixi Li, Yuyi Wang, Dan Cao, Xia Wang, Ming Jiang, Mei Li, Xi Yan, Yan Li, Yanyang Liu, Feng Luo
Pages: 2981-2991
Published online on: 07 April 2015

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Article

Establishment of a novel orthotopic model of breast cancer metastasis to the lung

Wenli Guo, Shuping Zhang, Sijin Liu
Pages: 2992-2998
Published online on: 27 April 2015

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Article

SHP-1 overexpression increases the radioresistance of NPC cells by enhancing DSB repair, increasing S phase arrest and decreasing cell apoptosis

Xiaofen Pan, Jingjing Mou, Sha Liu, Ziyi Sun, Rui Meng, Zhenwei Zhou, Gang Wu, Gang Peng
Pages: 2999-3005
Published online on: 28 April 2015

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Article

RACK1 modulates apoptosis induced by sorafenib in HCC cells by interfering with the IRE1/XBP1 axis

Ti Zhou, Xing Lv, Xin Guo, Bai Ruan, Dong Liu, Rui Ding, Yuan Gao, Jie Ding, Kefeng Dou, Yong Chen
Pages: 3006-3014
Published online on: 21 April 2015

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Article

Effects of emodin on the demethylation of tumor-suppressor genes in pancreatic cancer PANC-1 cells

Hao Zhang, Liang Chen, He-Qi Bu, Qing-Jiang Yu, Dan-Dan Jiang, Feng-Ping Pan, Yu Wang, Dian-Lei Liu, Sheng-Zhang Lin
Pages: 3015-3023
Published online on: 17 April 2015

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Article

Negative expression of PTEN identifies high risk for lymphatic-related metastasis in human esophageal squamous cell carcinoma

Zhenguo Sun, Na Ji, Mingming Bi, Zhiping Zhang, Xiangyan Liu, Zhou Wang
Pages: 3024-3032
Published online on: 27 April 2015

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Article

Cellular leiomyoma with necrosis and mucinous degeneration presenting as pseudo-Meigs' syndrome with elevated CA125

Ruiying Dong, Chengjuan Jin, Qing Zhang, Xingsheng Yang, Beihua Kong
Pages: 3033-3037
Published online on: 16 April 2015

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Article

Acidified bile acids increase hTERT expression via c-myc activation in human gastric cancer cells

Xiaolong Wang, Peihua Zhou, Xuejun Sun, Jianbao Zheng, Guangbing Wei, Li Zhang, Hui Wang, Jianfeng Yao, Shaoying Lu, Pengbo Jia
Pages: 3038-3044
Published online on: 09 April 2015

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Article

H19 lncRNA mediates 17β-estradiol-induced cell proliferation in MCF-7 breast cancer cells

Hong Sun, Guo Wang, Yan Peng, Ying Zeng, Qiong-Ni Zhu, Tai-Lin Li, Jia-Qin Cai, Hong-Hao Zhou, Yuan-Shan Zhu
Pages: 3045-3052
Published online on: 03 April 2015

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Article

miR-154 suppresses non-small cell lung cancer growth in vitro and in vivo Retraction in /10.3892/or.2023.8558

Xingyu Lin, Zhiguang Yang, Peng Zhang, Guoguang Shao
Pages: 3053-3060
Published online on: 02 April 2015

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Article

Cantharidin inhibits cell proliferation and promotes apoptosis in tongue squamous cell carcinoma through suppression of miR-214 and regulation of p53 and Bcl-2/Bax

Xiaoguang Tian, Guang Zeng, Xi Li, Zizhong Wu, Lei Wang
Pages: 3061-3068
Published online on: 28 April 2015

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Article

miR-34c plays a role of tumor suppressor in HEC‑1-B cells by targeting E2F3 protein

Fuyao Li, Huijun Chen, Yibo Huang, Qian Zhang, Jisen Xue, Zan Liu, Feiyun Zheng
Pages: 3069-3074
Published online on: 02 April 2015

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Article

The prognostic significance of PD-L1 in bladder cancer

Yide Huang, Shu-Dong Zhang, Cian McCrudden, Kwok-Wah Chan, Yao Lin, Hang-Fai Kwok
Pages: 3075-3084
Published online on: 27 April 2015

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Article

Butein suppresses cervical cancer growth through the PI3K/AKT/mTOR pathway

Xue Bai, Yaxin Ma, Guobin Zhang
Pages: 3085-3092
Published online on: 24 April 2015

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Article

Pooled analysis of Swedish case-control studies during 1997‑2003 and 2007-2009 on meningioma risk associated with the use of mobile and cordless phones

Michael Carlberg, Lennart Hardell
Pages: 3093-3098
Published online on: 27 April 2015

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Article

Propranolol represses infantile hemangioma cell growth through the β2-adrenergic receptor in a HIF-1α-dependent manner

Peng Li, Zhengtuan Guo, Ya Gao, Weikang Pan
Pages: 3099-3107
Published online on: 14 April 2015

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Article

Overexpression of miR-21 promotes the proliferation and migration of cervical cancer cells via the inhibition of PTEN

Jingjie Xu, Wei Zhang, Qiongying Lv, Dingjun Zhu
Pages: 3108-3116
Published online on: 27 April 2015

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Article

Sesamin inhibits lipopolysaccharide-induced proliferation and invasion through the p38-MAPK and NF-κB signaling pathways in prostate cancer cells

Peiyuan Xu, Fei Cai, Xiaofei Liu, Lele Guo
Pages: 3117-3123
Published online on: 31 March 2015

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Article

Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Pages: 3124-3130
Published online on: 07 April 2015

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Relative expression of rRNA transcripts and 45S rDNA promoter methylation status are dysregulated in tumors in comparison with matched-normal tissues in breast cancer

Gurbet Karahan, Nilufer Sayar, Gokcen Gozum, Betul Bozkurt, Ozlen Konu, Isik G. Yulug
Pages: 3131-3145
Published online on: 28 April 2015

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Article

Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60 leukemia cells through inhibition of the PI3K-AKT signaling pathway

Chengjun Hu, Maozhong Xu, Rujuan Qin, Weifeng Chen, Xin Xu
Pages: 3146-3154
Published online on: 02 April 2015

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Article

mRNA expression levels of hypoxia-induced and stem cell-associated genes in human glioblastoma

Matthias Bache, Swetlana Rot, Jacqueline Keßler, Antje Güttler, Henri Wichmann, Thomas Greither, Sven Wach, Helge Taubert, Ariane Söling, Udo Bilkenroth, Matthias Kappler, Dirk Vordermark
Pages: 3155-3161
Published online on: 27 April 2015

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Article

Structure elucidation, anticancer and antioxidant activities of a novel polysaccharide from Gomphus clavatus Gray

Xiang Ding, Yiling Hou, Yuanxiu Zhu, Panpan Wang, Lei Fu, Hongqing Zhu, Nan Zhang, Hang Qin, Wei Qu, Fang Wang, Wanru Hou
Pages: 3162-3170
Published online on: 21 April 2015

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Article

FOXM1-mediated downregulation of uPA and MMP9 by 3,3'-diindolylmethane inhibits migration and invasion of human colorectal cancer cells

Hua Jin, Xiu Juan Li, Man Hee Park, Soo Mi Kim
Pages: 3171-3177
Published online on: 28 April 2015

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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