|
1
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics, 2013. CA Cancer J Clin. 63:11–30. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
DeSantis C, Siegel R, Bandi P and Jemal A:
Breast cancer statistics, 2011. CA Cancer J Clin. 61:409–418. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Lluch A, Cueva J, Ruiz-Borrego M and Ponce
J: Pérez-Fidalgo JA Zoledronic acid in the treatment of metastatic
breast cancer. Anticancer Drugs. 25:1–7. 2014. View Article : Google Scholar
|
|
4
|
Hayashi K, Aono M, Shintam K and Kazuki K:
Bisphosphonate-related atypical femoral fracture with bone
metastasis of breast cancer Case report and review. Anticancer Res.
34:1245–1249. 2014.PubMed/NCBI
|
|
5
|
Minn AJ, Gupta GP, Padua D, Bos P, Nguyen
DX, Nuyten D, Kreike B, Zhang Y, Wang Y, Ishwaran H, et al: Lung
metastasis genes couple breast tumor size and metastatic spread.
Proc Natl Acad Sei USA. 104:6740–6745. 2007. View Article : Google Scholar
|
|
6
|
Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu
W, Gin DD, Viale A, Olshen AB, Gerald WL and Massagué J: Genes that
mediate breast cancer metastasis to lung. Nature. 436:518–524.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Aslakson CJ and Miller FR: Selective
events in the metastatic process defined by analysis of the
sequential dissemination of subpopulations of a mouse mammary
tumor. Cancer Res. 52:1399–1405. 1992.PubMed/NCBI
|
|
8
|
Tao K, Fang M, Alroy J and Sahagian GG:
Imagable 4T1 model for the study of late stage breast cancer. BMC
Cancer. 8:2282008. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Pulaski BA and Ostrand-Rosenberg S:
Reduction of established spontaneous mammary carcinoma metastases
following immunotherapy with major histocompatibility complex class
II and B71 cell-based tumor vaccines. Cancer Res. 58:1486–1493.
1998.PubMed/NCBI
|
|
10
|
Eckhardt BL, Parker BS, van Laar RK,
Restall CM, Natoli AL, Tavaria MD, Stanley KL, Sloan EK, Moseley JM
and Anderson RL: Genomic analysis of a spontaneous model of breast
cancer metastasis to bone reveals a role for the extracellular
matrix. Mol Cancer Res. 3:1–13. 2005.PubMed/NCBI
|
|
11
|
Miller FR, Miller BE and Heppner GH:
Characterization of metastatic heterogeneity among subpopulations
of a single mouse mammary tumor Heterogeneity in phenotypic
stability. Invasion Metastasis. 3:22–31. 1983.
|
|
12
|
Liu S, Goldstein RH, Scepansky EM and
Rosenblatt M: Inhibition of rho-associated kinase signaling
prevents breast cancer metastasis to human bone. Cancer Res.
69:8742–8751. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Liu S, Li S and Du Y: Polychlorinated
biphenyls (PCBs) enhance metastatic properties of breast cancer
cells by activating Rho-associated kinase (ROCK). PLoS One.
5:ell2722010.
|
|
14
|
Brocks C, Graefe H, Frenzel H, Pries R and
Wollenberg B: Isolation of human myeloid dendritic cells from tumor
tissue and peripheral blood. In Vivo. 20:239–242. 2006.PubMed/NCBI
|
|
15
|
Padua D, Zhang XH, Wang Q, Nadal C, Gerald
WL, Gomis RR and Massagué J: TGFbeta primes breast tumors for lung
metastasis seeding through angiopoietin-like 4. Cell. 133:66–77.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Lelekakis M, Moseley JM, Martin TJ, Hards
D, Williams E, Ho P, Lowen D, Javni J, Miller FR, Slavin J, et al:
A novel orthotopic model of breast cancer metastasis to bone. Clin
Exp Metastasis. 17:163–170. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Nieto MA: The ins and outs of the
epithelial to mesenchymal transition in health and disease. Annu
Rev Cell Dev Biol. 27:347–376. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
De Craene B and Berx G: Regulatory
networks defining EMT during cancer initiation and progression. Nat
Rev Cancer. 13:97–110. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
19
|
Foubert E, De Craene B and Berx G: Key
signalling nodes in mammary gland development and cancer The
Snaill-Twistl conspiracy in malignant breast cancer progression.
Breast Cancer Res. 12:2062010. View
Article : Google Scholar
|
|
20
|
Kaufhold S and Bonavida B: Central role of
Snail1 in the regulation of EMT and resistance in cancer: A target
for therapeutic intervention. J Exp Clin Cancer Res. 33:622014.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kajita M, McClinic KN and Wade PA:
Aberrant expression of the transcription factors snail and slug
alters the response to genotoxic stress. Mol Cell Biol.
24:7559–7566. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Ikenouchi J, Matsuda M, Furuse M and
Tsukita S: Regulation of tight junctions during the
epithelium-mesenchyme transition: Direct repression of the gene
expression of claudins/occludin by Snail. J Cell Sci.
116:1959–1967. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Bibby MC: Orthotopic models of cancer for
preclinical drug evaluation: Advantages and disadvantages. Eur J
Cancer. 40:852–857. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Parsons JT, Zetter B and Mohla S: Shifting
paradigms in tumor metastasis: Challenges and opportunities. Cancer
Biol Ther. 1:582–585. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Goldstein RH, Weinberg RA and Rosenblatt
M: Of mice and (wo)men: Mouse models of breast cancer metastasis to
bone. J Bone Miner Res. 25:431–436. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Vernon AE, Bakewell SJ and Chodosh LA:
Deciphering the molecular basis of breast cancer metastasis with
mouse models. Rev Endocr Metab Disord. 8:199–213. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Valastyan S and Weinberg RA: Tumor
metastasis: Molecular insights and evolving paradigms. Cell.
147:275–292. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Ansieau S: EMT in breast cancer stem cell
generation. Cancer Lett. 338:63–68. 2013. View Article : Google Scholar
|
|
29
|
Gradilone A, Raimondi C, Nicolazzo C,
Petracca A, Gandini O, Vincenzi B, Naso G, Aglianò AM, Cortesi E
and Gazzaniga P: Circulating tumour cells lacking cytokeratin in
breast cancer: The importance of being mesenchymal. J Cell Mol Med.
15:1066–1070. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Roxanis I: Occurrence and significance of
epithelial-mesenchymal transition in breast cancer. J Clin Pathol.
66:517–521. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Taube JH, Herschkowitz JI, Komurov K, Zhou
AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, et
al: Core epithelial-to-mesenchymal transition interactome
gene-expression signature is associated with claudin-low and
metaplastic breast cancer subtypes. Proc Natl Acad Sci USA.
107:15449–15454. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Hennessy BT, Gonzalez-Angulo AM,
Stemke-Hale K, Gilcrease MZ, Krishnamurthy S, Lee JS, Fridlyand J,
Sahin A, Agarwal R, Joy C, et al: Characterization of a naturally
occurring breast cancer subset enriched in
epithelial-to-mesenchymal transition and stem cell characteristics.
Cancer Res. 69:4116–4124. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Herschkowitz JI, Simin K, Weigman VJ,
Mikaelian I, Usary J, Hu Z, Rasmussen KE, Jones LP, Assefnia S,
Chandrasekharan S, et al: Identification of conserved gene
expression features between murine mammary carcinoma models and
human breast tumors. Genome Biol. 8:R762007. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Liu S: The ROCK signaling and breast
cancer metastasis. Mol Biol Rep. 38:1363–1366. 2011. View Article : Google Scholar
|
|
35
|
Twiss F and de Rooij J: Cadherin
mechanotransduction in tissue remodeling. Cell Mol Life Sci.
70:4101–4116. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Schneider MR and Kolligs FT: E-cadherin’s
role in development, tissue homeostasis and disease: Insights from
mouse models: Tissue-specific inactivation of the adhesion protein
E-cadherin in mice reveals its functions in health and disease.
Bioessays. 37:294–304. 2015. View Article : Google Scholar
|
|
37
|
Nelson WJ, Dickinson DJ and Weis WI: Roles
of cadherins and catenins in cell-cell adhesion and epithelial cell
polarity. Prog Mol Biol Transl Sci. 116:3–23. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Jeanes A, Gottardi CJ and Yap AS:
Cadherins and cancer: How does cadherin dysfunction promote tumor
progression? Oncogene. 27:6920–6929. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Gheldof A and Berx G: Cadherins and
epithelial-to-mesenchymal transition. Prog Mol Biol Transl Sci.
116:317–336. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Farahani E, Patra HK, Jangamreddy JR,
Rashedi I, Kawalec M, Rao Pariti RK, Batakis P and Wiechec E: Cell
adhesion molecules and their relation to (cancer) cell stemness.
Carcinogenesis. 35:747–759. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Furuse M, Hirase T, Itoh M, Nagafuchi A,
Yonemura S and Tsukita S and Tsukita S: Occludin: A novel integral
membrane protein localizing at tight junctions. J Cell Biol.
123:1777–1788. 1993. View Article : Google Scholar : PubMed/NCBI
|
