|
1
|
Byun JY, Yoon SJ, Oh IH, Kim YA, Seo HY
and Lee YH: Economic burden of colorectal cancer in Korea. J Prev
Med Pub Health. 47:84–93. 2014. View Article : Google Scholar
|
|
2
|
Irrazábal T, Belcheva A, Girardin SE,
Martin A and Philpott DJ: The multifaceted role of the intestinal
microbiota in colon cancer. Mol Cell. 54:309–320. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Louis P, Hold GL and Flint HJ: The gut
microbiota, bacterial metabolites and colorectal cancer. Nat Rev
Microbiol. 12:661–672. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Kandekar S, Preet R, Kashyap M, Renu
Prasad MU, Mohapatra P, Das D, Satapathy SR, Siddharth S, Jain V,
Choudhuri M, et al: Structural elaboration of a natural product:
Identification of 3,3′-diindolylmethane aminophosphonate and urea
derivatives as potent anticancer agents. ChemMedChem. 8:1873–1884.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Li Y, Li X and Guo B: Chemopreventive
agent 3,3′-diindolylmethane selectively induces proteasomal
degradation of class I histone deacetylases. Cancer Res.
70:646–654. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Li XJ, Leem SH, Park MH and Kim SM:
Regulation of YAP through an Akt-dependent process by 3,
3′-diindolylmethane in human colon cancer cells. Int J Oncol.
43:1992–1998. 2013.PubMed/NCBI
|
|
7
|
Park C, Choi YW, Hyun SK, Kwon HJ, Hwang
HJ, Kim GY, Choi BT, Kim BW, Choi IW, Moon SK, et al: Induction of
G1 arrest and apoptosis by schisandrin C isolated from Schizandra
chinensis Baill in human leukemia U937 cells. Int J Mol Med.
24:495–502. 2009.PubMed/NCBI
|
|
8
|
Choi HJ, Lim Y and Park JH: Induction of
G1 and G2/M cell cycle arrests by the dietary compound
3,3′-diindolylmethane in HT-29 human colon cancer cells. BMC
Gastroenterol. 9:392009. View Article : Google Scholar
|
|
9
|
Bhatnagar N, Li X, Chen Y, Zhou X, Garrett
SH and Guo B: 3,3′-Diindolylmethane enhances the efficacy of
butyrate in colon cancer prevention through down-regulation of
survivin. Cancer Prev Res. 2:581–589. 2009. View Article : Google Scholar
|
|
10
|
Pappa G, Strathmann J, Löwinger M, Bartsch
H and Gerhäuser C: Quantitative combination effects between
sulforaphane and 3,3′-diindolylmethane on proliferation of human
colon cancer cells in vitro. Carcinogenesis. 28:1471–1477. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kim EJ, Park SY, Shin HK, Kwon DY, Surh YJ
and Park JH: Activation of caspase-8 contributes to
3,3′-diindolylmethane-induced apoptosis in colon cancer cells. J
Nutr. 137:31–36. 2007.
|
|
12
|
Lee KB, Ye S, Park MH, Park BH, Lee JS and
Kim SM: p63-Mediated activation of the β-catenin/c-Myc signaling
pathway stimulates esophageal squamous carcinoma cell invasion and
metastasis. Cancer Lett. 353:124–132. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Li XJ, Park ES, Park MH and Kim SM:
3,3′-Diindolylmethane suppresses the growth of gastric cancer cells
via activation of the Hippo signaling pathway. Oncol Rep.
30:2419–2426. 2013.PubMed/NCBI
|
|
14
|
Halasi M and Gartel AL: Targeting FOXM1 in
cancer. Biochem Pharmacol. 85:644–652. 2013. View Article : Google Scholar
|
|
15
|
Ahmad A, Kong D, Wang Z, Sarkar SH,
Banerjee S and Sarkar FH: Down-regulation of uPA and uPAR by
3,3′-diindolylmethane contributes to the inhibition of cell growth
and migration of breast cancer cells. J Cell Biochem. 108:916–925.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Chang X, Tou JC, Hong C, Kim HA, Riby JE,
Firestone GL and Bjeldanes LF: 3,3′-Diindolylmethane inhibits
angiogenesis and the growth of transplantable human breast
carcinoma in athymic mice. Carcinogenesis. 26:771–778. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kandala PK and Srivastava SK:
Diindolylmethane suppresses ovarian cancer growth and potentiates
the effect of cisplatin in tumor mouse model by targeting signal
transducer and activator of transcription 3 (STAT3). BMC Med.
10:92012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Kong D, Li Y, Wang Z, Banerjee S and
Sarkar FH: Inhibition of angiogenesis and invasion by
3,3′-diindolylmethane is mediated by the nuclear factor-kappaB
downstream target genes MMP-9 and uPA that regulated
bioavailability of vascular endothelial growth factor in prostate
cancer. Cancer Res. 67:3310–3319. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Rahimi M, Huang KL and Tang CK:
3,3′-Diindolylmethane (DIM) inhibits the growth and invasion of
drug-resistant human cancer cells expressing EGFR mutants. Cancer
Lett. 295:59–68. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wu T, Chen C, Li F, Chen Z, Xu Y, Xiao B
and Tao Z: 3,3′-Diindolylmethane inhibits the invasion and
metastasis of nasopharyngeal carcinoma cells in vitro and in vivo
by regulation of epithelial mesenchymal transition. Exp Ther Med.
7:1635–1638. 2014.PubMed/NCBI
|
|
21
|
Ribaux P, Irion O and Cohen M: An active
product of cruciferous vegetables, 3,3′-diindolylmethane, inhibits
invasive properties of extravillous cytotrophoblastic cells. Neuro
Endocrinol Lett. 33:133–137. 2012.
|
|
22
|
Rajoria S, Suriano R, George A, Shanmugam
A, Schantz SP, Geliebter J and Tiwari RK: Estrogen induced
metastatic modulators MMP-2 and MMP-9 are targets of
3,3′-diindolylmethane in thyroid cancer. PLoS One. 6:e158792011.
View Article : Google Scholar
|
|
23
|
Rajoria S, Suriano R, Wilson YL, Schantz
SP, Moscatello A, Geliebter J and Tiwari RK: 3,3′-Diindolylmethane
inhibits migration and invasion of human cancer cells through
combined suppression of ERK and AKT pathways. Oncol Rep.
25:491–497. 2011.
|
|
24
|
Xu N, Jia D, Chen W, Wang H, Liu F, Ge H,
Zhu X, Song Y, Zhang X, Zhang D, et al: FoxM1 is associated with
poor prognosis of non-small cell lung cancer patients through
promoting tumor metastasis. PLoS One. 8:e594122013. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kalin TV, Wang IC, Ackerson TJ, Major ML,
Detrisac CJ, Kalinichenko VV, Lyubimov A and Costa RH: Increased
levels of the FoxM1 transcription factor accelerate development and
progression of prostate carcinomas in both TRAMP and LADY
transgenic mice. Cancer Res. 66:1712–1720. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Kim IM, Ackerson T, Ramakrishna S,
Tretiakova M, Wang IC, Kalin TV, Major ML, Gusarova GA, Yoder HM,
Costa RH, et al: The Forkhead Box m1 transcription factor
stimulates the proliferation of tumor cells during development of
lung cancer. Cancer Res. 66:2153–2161. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Balli D, Zhang Y, Snyder J, Kalinichenko
VV and Kalin TV: Endothelial cell-specific deletion of
transcription factor FoxM1 increases urethane-induced lung
carcinogenesis. Cancer Res. 71:40–50. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Calvisi DF, Pinna F, Ladu S, Pellegrino R,
Simile MM, Frau M, De Miglio MR, Tomasi ML, Sanna V, Muroni MR, et
al: Forkhead box M1B is a determinant of rat susceptibility to
hepatocarcinogenesis and sustains ERK activity in human HCC. Gut.
58:679–687. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Chandran UR, Ma C, Dhir R, Bisceglia M,
Lyons-Weiler M, Liang W, Michalopoulos G, Becich M and Monzon FA:
Gene expression profiles of prostate cancer reveal involvement of
multiple molecular pathways in the metastatic process. BMC Cancer.
7:642007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Millour J, Constantinidou D, Stavropoulou
AV, Wilson MS, Myatt SS, Kwok JM, Sivanandan K, Coombes RC, Medema
RH, Hartman J, et al: FOXM1 is a transcriptional target of ERalpha
and has a critical role in breast cancer endocrine sensitivity and
resistance. Oncogene. 29:2983–2995. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Wen N, Wang Y, Wen L, Zhao SH, Ai ZH, Wang
Y, Wu B, Lu HX, Yang H, Liu WC, et al: Overexpression of FOXM1
predicts poor prognosis and promotes cancer cell proliferation,
migration and invasion in epithelial ovarian cancer. J Transl Med.
12:1342014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Takata A, Takiguchi S, Okada K, Takahashi
T, Kurokawa Y, Yamasaki M, Miyata H, Nakajima K, Mori M and Doki Y:
Clinicopathological and prognostic significance of FOXM1 expression
in esophageal squamous cell carcinoma. Anticancer Res.
34:2427–2432. 2014.PubMed/NCBI
|
|
33
|
Kong FF, Qu ZQ, Yuan HH, Wang JY, Zhao M,
Guo YH, Shi J, Gong XD, Zhu YL, Liu F, et al: Overexpression of
FOXM1 is associated with EMT and is a predictor of poor prognosis
in non-small cell lung cancer. Oncol Rep. 31:2660–2668.
2014.PubMed/NCBI
|
|
34
|
Xia L, Huang W, Tian D, Chen Z, Zhang L,
Li Y, Hu H, Liu J, Chen Z, Tang G, et al: ACP5, a direct
transcriptional target of FoxM1, promotes tumor metastasis and
indicates poor prognosis in hepatocellular carcinoma. Oncogene.
33:1395–1406. 2014. View Article : Google Scholar
|
|
35
|
Liu D, Zhang Z and Kong CZ: High FOXM1
expression was associated with bladder carcinogenesis. Tumour Biol.
34:1131–1138. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Chu XY, Zhu ZM, Chen LB, Wang JH, Su QS,
Yang JR, Lin Y, Xue LJ, Liu XB and Mo XB: FOXM1 expression
correlates with tumor invasion and a poor prognosis of colorectal
cancer. Acta Histochem. 114:755–762. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Li D, Wei P, Peng Z, Huang C, Tang H, Jia
Z, Cui J, Le X, Huang S and Xie K: The critical role of
dysregulated FOXM1-PLAUR signaling in human colon cancer
progression and metastasis. Clin Cancer Res. 19:62–72. 2013.
View Article : Google Scholar :
|
|
38
|
Ahmad A, Ali S, Wang Z, Ali AS, Sethi S,
Sakr WA, Raz A and Rahman KM: 3,3′-Diindolylmethane enhances
taxotere-induced growth inhibition of breast cancer cells through
downregulation of FoxM1. Int J Cancer. 129:1781–1791. 2011.
View Article : Google Scholar
|
|
39
|
Ahmad A, Sakr WA and Rahman KM: Novel
targets for detection of cancer and their modulation by
chemopreventive natural compounds. Front Biosci. 4:410–425. 2012.
View Article : Google Scholar
|
|
40
|
Ahmad A, Ali S, Ahmed A, Ali AS, Raz A,
Sakr WA and Rahman KM: 3, 3′-Diindolylmethane enhances the
effectiveness of herceptin against HER-2/neu-expressing breast
cancer cells. PLoS One. 8:e546572013. View Article : Google Scholar
|
|
41
|
Ahmad A, Wang Z, Kong D, Ali S, Li Y,
Banerjee S, Ali R and Sarkar FH: FoxM1 down-regulation leads to
inhibition of proliferation, migration and invasion of breast
cancer cells through the modulation of extra-cellular matrix
degrading factors. Breast Cancer Res Treat. 122:337–346. 2010.
View Article : Google Scholar
|
