|
1
|
Löwenberg B, Downing JR and Burnett A:
Acute myeloid leukemia. N Engl J Med. 341:1051–1062. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Liesveld JL, Bechelli J, Rosell K, Lu C,
Bridger G, Phillips G II and Abboud CN: Effects of AMD3100 on
transmigration and survival of acute myelogenous leukemia cells.
Leuk Res. 31:1553–1563. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Lane SW, Wang YJ, Lo Celso C, Ragu C,
Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland
DG, et al: Differential niche and Wnt requirements during acute
myeloid leukemia progression. Blood. 118:2849–2856. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Krause DS, Fulzele K, Catic A, Sun CC,
Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, et al:
Differential regulation of myeloid leukemias by the bone marrow
microenvironment. Nat Med. 19:1513–1517. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Moshaver B, van der Pol MA, Westra AH,
Ossenkoppele GJ, Zweegman S and Schuurhuis GJ: Chemotherapeutic
treatment of bone marrow stromal cells strongly affects their
protective effect on acute myeloid leukemia cell survival. Leuk
Lymphoma. 49:134–148. 2008. View Article : Google Scholar
|
|
6
|
Konopleva M, Konoplev S, Hu W, Zaritskey
AY, Afanasiev BV and Andreeff M: Stromal cells prevent apoptosis of
AML cells by up-regulation of anti-apoptotic proteins. Leukemia.
16:1713–1724. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Mercier FE, Ragu C and Scadden DT: The
bone marrow at the crossroads of blood and immunity. Nat Rev
Immunol. 12:49–60. 2012. View
Article : Google Scholar
|
|
8
|
Peled A and Tavor S: Role of CXCR4 in the
pathogenesis of acute myeloid leukemia. Theranostics. 3:34–39.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Tokoyoda K, Egawa T, Sugiyama T, Choi BI
and Nagasawa T: Cellular niches controlling B lymphocyte behavior
within bone marrow during development. Immunity. 20:707–718. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Foudi A, Jarrier P, Zhang Y, Wittner M,
Geay JF, Lecluse Y, Nagasawa T, Vainchenker W and Louache F:
Reduced retention of radioprotective hematopoietic cells within the
bone marrow microenvironment in CXCR4−/− chimeric mice.
Blood. 107:2243–2251. 2006. View Article : Google Scholar
|
|
11
|
Fricker SP, Anastassov V, Cox J, Darkes
MC, Grujic O, Idzan SR, Labrecque J, Lau G, Mosi RM, Nelson KL, et
al: Characterization of the molecular pharmacology of AMD3100: A
specific antagonist of the G-protein coupled chemokine receptor,
CXCR4. Biochem Pharmacol. 72:588–596. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Burger JA and Peled A: CXCR4 antagonists:
Targeting the microenvironment in leukemia and other cancers.
Leukemia. 23:43–52. 2009. View Article : Google Scholar
|
|
13
|
Zhang Y, Patel S, Abdelouahab H, Wittner
M, Willekens C, Shen S, Betems A, Joulin V, Opolon P, Bawa O, et
al: CXCR4 inhibitors selectively eliminate CXCR4-expressing human
acute myeloid leukemia cells in NOG mouse model. Cell Death Dis.
3:e3962012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Zeng Z, Shi YX, Samudio IJ, Wang RY, Ling
X, Frolova O, Levis M, Rubin JB, Negrin RR, Estey EH, et al:
Targeting the leukemia microenvironment by CXCR4 inhibition
overcomes resistance to kinase inhibitors and chemotherapy in AML.
Blood. 113:6215–6224. 2009. View Article : Google Scholar :
|
|
15
|
Sison EA, McIntyre E, Magoon D and Brown
P: Dynamic chemotherapy-induced upregulation of CXCR4 expression: A
mechanism of therapeutic resistance in pediatric AML. Mol Cancer
Res. 11:1004–1016. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Nervi B, Ramirez P, Rettig MP, Uy GL, Holt
MS, Ritchey JK, Prior JL, Piwnica-Worms D, Bridger G, Ley TJ, et
al: Chemo-sensitization of acute myeloid leukemia (AML) following
mobilization by the CXCR4 antagonist AMD3100. Blood. 113:6206–6214.
2009. View Article : Google Scholar :
|
|
17
|
Lee JY, Park S, Min WS and Kim HJ:
Restoration of natural killer cell cytotoxicity by VEGFR-3
inhibition in myelogenous leukemia. Cancer Lett. 354:281–289. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Kremer KN, Peterson KL, Schneider PA, Meng
XW, Dai H, Hess AD, Smith BD, Rodriguez-Ramirez C, Karp JE,
Kaufmann SH, et al: CXCR4 chemokine receptor signaling induces
apoptosis in acute myeloid leukemia cells via regulation of the
Bcl-2 family members Bcl-XL, Noxa, and Bak. J Biol Chem.
288:22899–22914. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Mannelli F, Cutini I, Gianfaldoni G,
Bencini S, Scappini B, Pancani F, Ponziani V, Bonetti MI, Biagiotti
C, Longo G, et al: CXCR4 expression accounts for clinical phenotype
and outcome in acute myeloid leukemia. Cytometry B Clin Cytom.
86:340–349. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Müller A, Homey B, Soto H, Ge N, Catron D,
Buchanan ME, McClanahan T, Murphy E, Yuan W, Wagner SN, et al:
Involvement of chemokine receptors in breast cancer metastasis.
Nature. 410:50–56. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
21
|
de Oliveira KB, Guembarovski RL,
Guembarovski AM, da Silva do Amaral Herrera AC, Sobrinho WJ, Ariza
CB and Watanabe MA: CXCL12, CXCR4 and IFNγ genes expression:
Implications for proinflammatory microenvironment of breast cancer.
Clin Exp Med. 13:211–219. 2013. View Article : Google Scholar
|
|
22
|
Meads MB, Hazlehurst LA and Dalton WS: The
bone marrow microenvironment as a tumor sanctuary and contributor
to drug resistance. Clin Cancer Res. 14:2519–2526. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kopp HG, Avecilla ST, Hooper AT and Rafii
S: The bone marrow vascular niche: Home of HSC differentiation and
mobilization. Physiology (Bethesda). 20:349–356. 2005. View Article : Google Scholar
|
|
24
|
Psaila B, Lyden D and Roberts I:
Megakaryocytes, malignancy and bone marrow vascular niches. J
Thromb Haemost. 10:177–188. 2012. View Article : Google Scholar :
|
|
25
|
Yin T and Li L: The stem cell niches in
bone. J Clin Invest. 116:1195–1201. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Balabanian K, Brotin E, Biajoux V,
Bouchet-Delbos L, Lainey E, Fenneteau O, Bonnet D, Fiette L, Emilie
D and Bachelerie F: Proper desensitization of CXCR4 is required for
lymphocyte development and peripheral compartmentalization in mice.
Blood. 119:5722–5730. 2012. View Article : Google Scholar : PubMed/NCBI
|
