|
1
|
Gordaliza M: Natural products as leads to
anticancer drugs. Clinical & Translational Oncology: Official
Publication of the Federation of Spanish Oncology Societies and of
the National Cancer Institute of Mexico. 9:767–776. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wang Z, Jiang W, Zhang Z, Qian M and Du B:
Nitidine chloride inhibits LPS-induced inflammatory cytokines
production via MAPK and NF-kappaB pathway in RAW 264.7 cells. J
Ethnopharmacol. 144:145–150. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Del Poeta M, Chen SF, Von Hoff D, Dykstra
CC, Wani MC, Manikumar G, Heitman J, Wall ME and Perfect JR:
Comparison of in vitro activities of camptothecin and nitidine
derivatives against fungal and cancer cells. Antimicrob Agents
Chemother. 43:2862–2868. 1999.PubMed/NCBI
|
|
4
|
Liao J, Xu T, Zheng JX, Lin JM, Cai QY, Yu
DB and Peng J: Nitidine chloride inhibits hepatocellular carcinoma
cell growth in vivo through the suppression of the JAK1/STAT3
signaling pathway. Int J Mol Med. 32:79–84. 2013.PubMed/NCBI
|
|
5
|
Chen J, Wang J, Lin L, He L, Wu Y, Zhang
L, Yi Z, Chen Y, Pang X and Liu M: Inhibition of STAT3 signaling
pathway by nitidine chloride suppressed the angiogenesis and growth
of human gastric cancer. Mol Cancer Ther. 11:277–287. 2012.
View Article : Google Scholar
|
|
6
|
Pan X, Han H, Wang L, Yang L, Li R, Li Z,
Liu J, Zhao Q, Qian M, Liu M, et al: Nitidine chloride inhibits
breast cancer cells migration and invasion by suppressing c-Src/FAK
associated signaling pathway. Cancer Lett. 313:181–191. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Sun M, Zhang N, Wang X, Cai C, Cun J, Li
Y, Lv S and Yang Q: Nitidine chloride induces apoptosis, cell cycle
arrest, and synergistic cytotoxicity with doxorubicin in breast
cancer cells. Tumour Biol. 35:10201–10212. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Fang Z, Tang Y, Jiao W, Xing Z, Guo Z,
Wang W, Xu Z and Liu Z: Nitidine chloride induces apoptosis and
inhibits tumor cell proliferation via suppressing ERK signaling
pathway in renal cancer. Food Chem Toxicol. 66:210–216. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Fang Z, Tang Y, Jiao W, Xing Z, Guo Z,
Wang W, Shi B, Xu Z and Liu Z: Nitidine chloride inhibits renal
cancer cell metastasis via suppressing AKT signaling pathway. Food
Chem Toxicol. 60:246–251. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kang M, Ou H, Wang R, Liu W and Tang A:
The effect of nitidine chloride on the proliferation and apoptosis
of nasopharyngeal carcinoma cells. J BUON. 19:130–136.
2014.PubMed/NCBI
|
|
11
|
Liu N, Li P, Zang S, Liu Q, Ma D, Sun X
and Ji C: Novel agent nitidine chloride induces erythroid
differentiation and apoptosis in CML cells through c-Myc-miRNAs
axis. PLoS One. 10:e01168802015. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Ottaviani G and Jaffe N: The epidemiology
of osteosarcoma. Cancer Treat Res. 152:3–13. 2009. View Article : Google Scholar
|
|
13
|
Mirabello L, Troisi RJ and Savage SA:
Osteosarcoma incidence and survival rates from 1973 to 2004: Data
from the Surveillance, Epidemiology, and End Results Program.
Cancer. 115:1531–1543. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Huh WW, Holsinger FC, Levy A, Palla FS and
Anderson PM: Osteosarcoma of the jaw in children and young adults.
Head Neck. 34:981–984. 2012. View Article : Google Scholar
|
|
15
|
Gaffney R, Unni KK, Sim FH, Slezak JM,
Esther RJ and Bolander ME: Follow-up study of long-term survivors
of osteosarcoma in the prechemotherapy era. Hum Pathol.
37:1009–1014. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Mohseny AB, Machado I, Cai Y, Schaefer KL,
Serra M, Hogendoorn PC, Llombart-Bosch A and Cleton-Jansen AM:
Functional characterization of osteosarcoma cell lines provides
representative models to study the human disease. Lab Invest.
91:1195–1205. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Vuoriluoto K, Haugen H, Kiviluoto S,
Mpindi JP, Nevo J, Gjerdrum C, Tiron C, Lorens JB and Ivaska J:
Vimentin regulates EMT induction by Slug and oncogenic H-Ras and
migration by governing Axl expression in breast cancer. Oncogene.
30:1436–1448. 2011. View Article : Google Scholar
|
|
18
|
Rosanò L, Cianfrocca R, Spinella F, Di
Castro V, Nicotra MR, Lucidi A, Ferrandina G, Natali PG and Bagnato
A: Acquisition of chemoresistance and EMT phenotype is linked with
activation of the endothelin A receptor pathway in ovarian
carcinoma cells. Clin Cancer Res. 17:2350–2360. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Elloul S, Vaksman O, Stavnes HT, Trope CG,
Davidson B and Reich R: Mesenchymal-to-epithelial transition
determinants as characteristics of ovarian carcinoma effusions.
Clin Exp Metastasis. 27:161–172. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Liu J, Gao L, Zhang H, Wang D, Wang M, Zhu
J, Pang C and Wang C: Succinate dehydrogenase 5 (SDH5) regulates
glycogen synthase kinase 3β-β-catenin-mediated lung cancer
metastasis. J Biol Chem. 288:29965–29973. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhou SL, Zhou ZJ, Hu ZQ, Li X, Huang XW,
Wang Z, Fan J, Dai Z and Zhou J: CXCR2/CXCL5 axis contributes to
epithelial-mesenchymal transition of HCC cells through activating
PI3K/Akt/GSK-3β/Snail signaling. Cancer Lett. 358:124–135. 2015.
View Article : Google Scholar
|
|
22
|
Yoshimura T, Kawano Y, Arimura N, Kawabata
S, Kikuchi A and Kaibuchi K: GSK-3beta regulates phosphorylation of
CRMP-2 and neuronal polarity. Cell. 120:137–149. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Liu C, Li Y, Semenov M, Han C, Baeg GH,
Tan Y, Zhang Z, Lin X and He X: Control of beta-catenin
phosphorylation/degradation by a dual-kinase mechanism. Cell.
108:837–847. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zhang X, Chen T, Zhang J, Mao Q, Li S,
Xiong W, Qiu Y, Xie Q and Ge J: Notch1 promotes glioma cell
migration and invasion by stimulating β-catenin and NF-κB signaling
via AKT activation. Cancer Sci. 103:181–190. 2012. View Article : Google Scholar
|
|
25
|
Yuan H, Kajiyama H, Ito S, Yoshikawa N,
Hyodo T, Asano E, Hasegawa H, Maeda M, Shibata K, Hamaguchi M, et
al: ALX1 induces snail expression to promote
epithelial-to-mesenchymal transition and invasion of ovarian cancer
cells. Cancer Res. 73:1581–1590. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Mitra A, Mishra L and Li S: EMT, CTCs and
CSCs in tumor relapse and drug-resistance. Oncotarget.
6:10697–10711. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Qureshi R, Arora H and Rizvi MA: EMT in
cervical cancer: Its role in tumour progression and response to
therapy. Cancer Lett. 356:321–331. 2015. View Article : Google Scholar
|
|
28
|
Somanath PR, Vijai J, Kichina JV, Byzova T
and Kandel ES: The role of PAK-1 in activation of MAP kinase
cascade and oncogenic transformation by Akt. Oncogene.
28:2365–2369. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
de Araújo WM, Vidal FC, de Souza WF, de
Freitas JC Jr, de Souza W and Morgado-Diaz JA: PI3K/Akt and GSK-3β
prevents in a differential fashion the malignant phenotype of
colorectal cancer cells. J Cancer Res Clin Oncol. 136:1773–1782.
2010. View Article : Google Scholar
|
|
30
|
Zhang B, Yang Y, Shi X, Liao W, Chen M,
Cheng AS, Yan H, Fang C, Zhang S, Xu G, et al: Proton pump
inhibitor pantoprazole abrogates adriamycin-resistant gastric
cancer cell invasiveness via suppression of Akt/GSK-β/β-catenin
signaling and epithelial-mesenchymal transition. Cancer Lett.
356:704–712. 2015. View Article : Google Scholar
|
|
31
|
Chen J, Chan AW, To KF, Chen W, Zhang Z,
Ren J, Song C, Cheung YS, Lai PB, Cheng SH, et al: SIRT2
overexpression in hepatocellular carcinoma mediates epithelial to
mesenchymal transition by protein kinase B/glycogen synthase
kinase-3β/β-catenin signaling. Hepatology. 57:2287–2298. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Liu ZC, Wang HS, Zhang G, Liu H, Chen XH,
Zhang F, Chen DY, Cai SH and Du J: AKT/GSK-3β regulates stability
and transcription of snail which is crucial for bFGF-induced
epithelial-mesenchymal transition of prostate cancer cells. Biochim
Biophys Acta. 1840:3096–3105. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Liu CW, Li CH, Peng YJ, Cheng YW, Chen HW,
Liao PL, Kang JJ and Yeng MH: Snail regulates Nanog status during
the epithelial-mesenchymal transition via the Smad1/Akt/GSK3β
signaling pathway in non-small-cell lung cancer. Oncotarget.
5:3880–3894. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Lu ZY, Dong R, Li D, Li WB, Xu FQ, Geng Y
and Zhang YS: SNAI1 overexpression induces stemness and promotes
ovarian cancer cell invasion and metastasis. Oncol Rep.
27:1587–1591. 2012.PubMed/NCBI
|
|
35
|
Surh YJ: Cancer chemoprevention with
dietary phytochemicals. Nat Rev Cancer. 3:768–780. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Thomasset SC, Berry DP, Garcea G, Marczylo
T, Steward WP and Gescher AJ: Dietary polyphenolic phytochemicals -
promising cancer chemopreventive agents in humans? A review of
their clinical properties. Int J Cancer. 120:451–458. 2007.
View Article : Google Scholar
|
|
37
|
Weng CJ and Yen GC: Chemopreventive
effects of dietary phytochemicals against cancer invasion and
metastasis: Phenolic acids, monophenol, polyphenol, and their
derivatives. Cancer Treat Rev. 38:76–87. 2012. View Article : Google Scholar
|
|
38
|
Turley EA, Veiseh M, Radisky DC and
Bissell MJ: Mechanisms of disease: Epithelial-mesenchymal
transition - does cellular plasticity fuel neoplastic progression?
Nat Clin Pract Oncol. 5:280–290. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Hou CH, Lin FL, Hou SM and Liu JF: Cyr61
promotes epithelial-mesenchymal transition and tumor metastasis of
osteosarcoma by Raf-1/MEK/ERK/Elk-1/TWIST-1 signaling pathway. Mol
Cancer. 13:2362014. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Guo X, Zhang J, Pang J, He S, Li G, Chong
Y, Li C, Jiao Z, Zhang S and Shao M: MicroRNA-503 represses
epithelial-mesenchymal transition and inhibits metastasis of
osteosarcoma by targeting c-myb. Tumour Biol. Jan 14–2016.Epub
ahead of print. View Article : Google Scholar
|
|
41
|
Zhang X, Jiang D, Jiang W, Zhao M and Gan
J: Role of TLR4-mediated PI3K/AKT/GSK-3β signaling pathway in
apoptosis of rat hepatocytes. Biomed Res Int. 2015:6313262015.
|
|
42
|
Lin L, Chen YS, Yao YD, Chen JQ, Chen JN,
Huang SY, Zeng YJ, Yao HR, Zeng SH, Fu YS, et al: CCL18 from
tumor-associated macrophages promotes angiogenesis in breast
cancer. Oncotarget. 6:34758–34773. 2015.PubMed/NCBI
|
|
43
|
Liao K, Li J and Wang Z:
Dihydroartemisinin inhibits cell proliferation via
AKT/GSK3β/cyclinD1 pathway and induces apoptosis in A549 lung
cancer cells. Int J Clin Exp Pathol. 7:8684–8691. 2014.
|
|
44
|
Doble BW and Woodgett JR: GSK-3: Tricks of
the trade for a multi-tasking kinase. J Cell Sci. 116:1175–1186.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Ngo HK, Lee HG, Piao JY, Zhong X, Lee HN,
Han HJ, Kim W, Kim DH, Cha YN, Na HK, et al: Helicobacter pylori
induces Snail expression through ROS-mediated activation of Erk and
inactivation of GSK-3β in human gastric cancer cells. Mol Carcinog.
Jan 25–2016.Epub ahead of print. View Article : Google Scholar
|
|
46
|
Zhang B, Yin C, Li H, Shi L, Liu N, Sun Y,
Lu S, Liu Y, Sun L, Li X, et al: Nir1 promotes invasion of breast
cancer cells by binding to chemokine (C-C motif) ligand 18 through
the PI3K/Akt/GSK3β/Snail signalling pathway. Eur J Cancer.
49:3900–3913. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Zhang J, Wei J, Lu J, Tong Z, Liao B, Yu
B, Zheng F, Huang X, Chen Z, Fang Y, et al: Overexpression of Rab25
contributes to metastasis of bladder cancer through induction of
epithelial-mesenchymal transition and activation of
Akt/GSK-3β/Snail signaling. Carcinogenesis. 34:2401–2408. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Wang H, Wang HS, Zhou BH, Li CL, Zhang F,
Wang XF, Zhang G, Bu XZ, Cai SH and Du J: Epithelial-mesenchymal
transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated
stabilization of snail in colorectal cancer. PLoS One.
8:e566642013. View Article : Google Scholar
|
|
49
|
Maseki S, Ijichi K, Tanaka H, Fujii M,
Hasegawa Y, Ogawa T, Murakami S, Kondo E and Nakanishi H:
Acquisition of EMT phenotype in the gefitinib-resistant cells of a
head and neck squamous cell carcinoma cell line through
Akt/GSK-3β/snail signalling pathway. Br J Cancer. 106:1196–1204.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Cano A, Pérez-Moreno MA, Rodrigo I,
Locascio A, Blanco MJ, del Barrio MG, Portillo F and Nieto MA: The
transcription factor snail controls epithelial-mesenchymal
transitions by repressing E-cadherin expression. Nat Cell Biol.
2:76–83. 2000. View Article : Google Scholar : PubMed/NCBI
|
