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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2016 Volume 36 Issue 2

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Carcinogenetic mechanisms of endocrine disruptors in female cancers (Review)

Lino Del Pup, Alberto Mantovani, Carla Cavaliere, Gaetano Facchini, Amalia Luce, Pasquale Sperlongano, Michele Caraglia, Massimiliano Berretta
Pages: 603-612
Published online on: 21 June 2016

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Review Open Access

Accuracy of novel diagnostic biomarkers for hepatocellular carcinoma: An update for clinicians (Review)

Patrick Reichl, Wolfgang Mikulits
Pages: 613-625
Published online on: 01 June 2016

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Article Open Access

Continuous administration of bevacizumab plus capecitabine, even after acquired resistance to bevacizumab, restored anti-angiogenic and antitumor effect in a human colorectal cancer xenograft model

Toshiki Iwai, MasamichI Sugimoto, Suguru Harada, Keigo Yorozu, Mitsue Kurasawa, Kaname Yamamoto
Pages: 626-632
Published online on: 22 June 2016

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Article Open Access

MicroRNA-23a downregulates the expression of interferon regulatory factor-1 in hepatocellular carcinoma cells

Yihe Yan, Zhihai Liang, Qiang Du, Muqing Yang, David A. Geller
Pages: 633-640
Published online on: 09 June 2016

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Article Open Access

IL-17A-producing T cells are associated with the progression of lung adenocarcinoma

Zhang Bao, Guohua Lu, Dawei Cui, Yinan Yao, Guangdie Yang, Jianying Zhou
Pages: 641-650
Published online on: 27 May 2016

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Article Open Access

Regulation of tumorigenesis in oral epithelial cells by defined reprogramming factors Oct4 and Sox2

Jinghua Cai, Baoxia He, Xinming Li, Minglei Sun, Alfred King-Yin Lam, Bin Qiao, Weiliu Qiu
Pages: 651-658
Published online on: 03 June 2016

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Article Open Access

Incomplete radiofrequency ablation accelerates proliferation and angiogenesis of residual lung carcinomas via HSP70/HIF-1α

Jun Wan, Wei Wu, Yunlong Huang, Wei Ge, Shandong Liu
Pages: 659-668
Published online on: 07 June 2016

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Article Open Access

Downregulation of tetrahydrobiopterin inhibits tumor angiogenesis in BALB/c-nu mice with hepatocellular carcinoma

Youguo Dai, Jin Cui, Ping Gan, Weiming Li
Pages: 669-675
Published online on: 02 June 2016

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Article Open Access

Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells

Jian Ma, Yan-Ru Yang, Wei Chen, Mei-Hua Chen, Hao Wang, Xiao-Dan Wang, Li-Li Sun, Feng-Ze Wang, De-Cai Wang
Pages: 676-684
Published online on: 07 June 2016

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Article Open Access

The role of MAPK signaling pathway in the Her-2-positive meningiomas

Zhaoyin Wang, Weijia Wang, Shan Xu, Shanshan Wang, Yi Tu, Yifeng Xiong, Jinhong Mei, Chunliang Wang
Pages: 685-695
Published online on: 02 June 2016

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Article

Estimating subthreshold tumor on MRI using a 3D-DTI growth model for GBM: An adjunct to radiation therapy planning

Leith Hathout, Vishal Patel
Pages: 696-704
Published online on: 15 June 2016

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Article

Effects of estradiol on VEGF and bFGF by Akt in endometrial cancer cells are mediated through the NF-κB pathway

Jieqing Zhang, Honglin Song, Yanqiong Lu, Haiyan Chen, Si Jiang, Li Li
Pages: 705-714
Published online on: 21 June 2016

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Article

Rejection of adenovirus infection is independent of coxsackie and adenovirus receptor expression in cisplatin-resistant human lung cancer cells

Nian-Hua Zhang, Rui-Qing Peng, Ya Ding, Xiao-Shi Zhang
Pages: 715-720
Published online on: 13 June 2016

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Article

DT-13 inhibits cancer cell migration by regulating NMIIA indirectly in the tumor microenvironment

Hongzhi Du, Yue Huang, Xiaoyin Hou, Xiaowen Yu, Sensen Lin, Xiaohui Wei, Ruiming Li, Ghulam Jilany Khan, Shengtao Yuan, Li Sun
Pages: 721-728
Published online on: 22 June 2016

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Article

Knockdown of TAZ modifies triple-negative breast cancer cell sensitivity to EGFR inhibitors by regulating YAP expression

Liwen Guo, Jiaping Zheng, Jing Zhang, Haohao Wang, Guoliang Shao, Lisong Teng
Pages: 729-736
Published online on: 15 June 2016

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Article

p12CDK2-AP1 interacts with CD82 to regulate the proliferation and survival of human oral squamous cell carcinoma cells

Juan Chai, Jun Ju, Shao-Wu Zhang, Zhi-Yuan Shen, Liang Liang, Xiang-Ming Yang, Chao Ma, Qian-Wei Ni, Mo-Yi Sun
Pages: 737-744
Published online on: 22 June 2016

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Article

Inhibition of DACH1 activity by short hairpin RNA represses cell proliferation and tumor invasion in pancreatic cancer

Xiao-Na Bu, Chan Qiu, Chuan Wang, Zheng Jiang
Pages: 745-754
Published online on: 02 June 2016

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Article

Phosphorylated mTOR is associated to androgen receptor expression in early triple-negative breast cancer

M. Pistelli, Z. Ballatore, A. Santinelli, T. Biscotti, F. Piva, G. Occhipinti, A. Della Mora, A. Pagliacci, N. Battelli, L. Bastianelli, M. De Lisa, R. Bracci, E. Maccaroni, R. Berardi, S. Cascinu
Pages: 755-762
Published online on: 22 June 2016

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Article

Mechanisms of SU5416, an inhibitor of vascular endothelial growth factor receptor, as a radiosensitizer for colon cancer cells

Eun Ho Kim, Hanna Lee, Youn Kyoung Jeong, Won-Gyun Jung
Pages: 763-770
Published online on: 10 June 2016

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Article

Grape seed proanthocyanidins induce apoptosis through the mitochondrial pathway in nasopharyngeal carcinoma CNE-2 cells

Kai Yao, Jingjing Shao, Keyuan Zhou, Haitao Qiu, Fengxiang Cao, Caihong Li, De Dai
Pages: 771-778
Published online on: 03 June 2016

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Article

Ubiquitin-conjugating enzyme UbcH10 promotes gastric cancer growth and is a potential biomarker for gastric cancer

Mengxuan Yang, Yingying Qu, Rongliang Shi, Xubo Wu, Chang Su, Zhiqiu Hu, Qimeng Chang, Shaoqun Liu, Gaofeng Pan, Ming Lei, Fubo Xie, Shiwei Tu, Weikang Tao, He Zhou, Gang Hu, Ziping Zhang
Pages: 779-786
Published online on: 23 June 2016

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Article

Platelets surrounding primary tumor cells are related to chemoresistance

Satoko Ishikawa, Tomoharu Miyashita, Masafumi Inokuchi, Hironori Hayashi, Katsunobu Oyama, Hidehiro Tajima, Hironori Takamura, Itasu Ninomiya, A. Karim Ahmed, John W. Harman, Sachio Fushida, Tetsuo Ohta
Pages: 787-794
Published online on: 22 June 2016

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Article

Forkhead-box A1 induces cell senescence in endometrial cancer by regulating p16INK4a

Jingyun Wang, Yiding Bian, Yun Liao, Ye Xia, Xiaoping Wan
Pages: 795-802
Published online on: 23 June 2016

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Article

Promotion of epithelial-mesenchymal transition by Frizzled2 is involved in the metastasis of endometrial cancer

Yiding Bian, Xinwen Chang, Yun Liao, Jingyun Wang, Yiran Li, Kai Wang, Xiaoping Wan
Pages: 803-810
Published online on: 17 June 2016

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Article

Aberrant methylation of TRIM58 in hepatocellular carcinoma and its potential clinical implication

Xueping Qiu, Yifang Huang, Ye Zhou, Fang Zheng
Pages: 811-818
Published online on: 13 June 2016

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Article

Activation of the FAK/PI3K pathway is crucial for AURKA-induced epithelial-mesenchymal transition in laryngeal cancer

Liyun Yang, Quan Zhou, Xuehua Chen, Liping Su, Bingya Liu, Hao Zhang
Pages: 819-826
Published online on: 13 June 2016

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Article

Leukemia inhibitory factor receptor negatively regulates the metastasis of pancreatic cancer cells in vitro and in vivo

Ding Ma, Xiaoqian Jing, Baiyong Shen, Xinyu Liu, Xi Cheng, Bingrui Wang, Zhiping Fu, Chenghong Peng, Weihua Qiu
Pages: 827-836
Published online on: 09 June 2016

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Article

Histopathological implications of ventricle wall 5-aminolevulinic acid-induced fluorescence in the absence of tumor involvement on magnetic resonance images

Ju Hyung Moon, Se Hoon Kim, Jin‑Kyoung Shim, Tae‑Hoon Roh, Kyoung Su Sung, Ji‑Hyun Lee, Junseong Park, Junjeong Choi, Eui‑Hyun Kim, Sun Ho Kim, Seok‑Gu Kang, Jong Hee Chang
Pages: 837-844
Published online on: 16 June 2016

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Article

Proteasome inhibitor MG132 potentiates TRAIL-induced apoptosis in gallbladder carcinoma GBC-SD cells via DR5-dependent pathway

Weiping Zhu, Dihua Zhan, Lu Wang, Dening Ma, Mingrong Cheng, Huipeng Wang, Jiaying Zhao, Yuankun Cai, Zhijian Cheng
Pages: 845-852
Published online on: 27 May 2016

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Article

NEK2 regulates stem-like properties and predicts poor prognosis in hepatocellular carcinoma

Shuang Lin, Senjun Zhou, Shaojie Jiang, Xiaolong Liu, Yifan Wang, Xueyong Zheng, Haimeng Zhou, Xuhui Li, Xiujun Cai
Pages: 853-862
Published online on: 22 June 2016

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Article

Soft tissue sarcomas of the distal lower extremities: A single-institutional analysis of the prognostic significance of surgical margins in 120 patients

Kamran Harati, Pascal Kirchhoff, Björn Behr, Adrien Daigeler, Ole Goertz, Tobias Hirsch, Marcus Lehnhardt, Andrej Ring
Pages: 863-870
Published online on: 08 June 2016

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Article

Docetaxel-loaded PEG-albumin nanoparticles with improved antitumor efficiency against non-small cell lung cancer

Guangming Jin, Mingji Jin, Zhehu Jin, Zhonggao Gao, Xuezhe Yin
Pages: 871-876
Published online on: 08 June 2016

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Article

COL11A1 is overexpressed in recurrent non-small cell lung cancer and promotes cell proliferation, migration, invasion and drug resistance

Lihua Shen, Min Yang, Qionghua Lin, Zhongwei Zhang, Biao Zhu, Changhong Miao
Pages: 877-885
Published online on: 10 June 2016

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Article

Highly sensitive detection of leukemia cells based on aptamer and quantum dots Corrigendum in /10.3892/or.2025.8962

Yating Yu, Siliang Duan, Jian He, Wei Liang, Jing Su, Jianmeng Zhu, Nan Hu, Yongxiang Zhao, Xiaoling Lu
Pages: 886-892
Published online on: 10 June 2016

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Article

Lovastatin, but not orlistat, reduces intestinal polyp volume in an ApcMin/+ mouse model

Maria Notarnicola, Michele Barone, Antonio Francavilla, Valeria Tutino, Giusy Bianco, Angela Tafaro, Mario Minoia, Lorenzo Polimeno, Anna Napoli, Maria Principia Scavo, Maria Gabriella Caruso
Pages: 893-899
Published online on: 06 June 2016

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Article

SEMA3B improves the survival of patients with esophageal squamous cell carcinoma by upregulating p53 and p21

Hong Tang, Yufeng Wu, Ming Liu, Yanru Qin, Haiying Wang, Lili Wang, Shaomei Li, Hui Zhu, Zheng He, Junpeng Luo, Hongyan Wang, Qiming Wang, Suxia Luo
Pages: 900-908
Published online on: 22 June 2016

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Article

miR-126-3p and miR-451a correlate with clinicopathological features of lung adenocarcinoma: The underlying molecular mechanisms

Qingyong Chen, Huizhen Hu, Demin Jiao, Jie Yan, Wei Xu, Xiali Tang, Jun Chen, Jian Wang
Pages: 909-917
Published online on: 03 June 2016

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Article

NFATc1 regulates cell proliferation, migration, and invasion of ovarian cancer SKOV3 cells in vitro and in vivo

Long Li, Zhaoning Duan, Jihui Yu, Hong‑Xing Dang
Pages: 918-928
Published online on: 23 June 2016

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Article

Heterogeneous nuclear ribonucleoprotein K is overexpressed and associated with poor prognosis in gastric cancer

Ruirui Yang, Ying Zeng, Haifan Xu, Zhuo Chen, Mengqin Xiang, Yun Fu, Yufang Yin, Jing Zhong, Min Zeng, Peihua Wang, Qin You, Xi Zeng
Pages: 929-935
Published online on: 02 June 2016

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Article

Perichondrium mesenchymal stem cells inhibit the growth of breast cancer cells via the DKK-1/Wnt/β-catenin signaling pathway

Min Li, Hui Cai, Ya Yang, Jia Zhang, Kai Sun, Yan Yan, Hangying Qu, Weiwei Wang, Jiansheng Wang, Xiaoyi Duan
Pages: 936-944
Published online on: 03 June 2016

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Article

Targeting of MCT1 and PFKFB3 influences cell proliferation and apoptosis in bladder cancer by altering the tumor microenvironment

Ke Yao Hu, De Gui Wang, Peng Fei Liu, Yan Wei Cao, Yong Hua Wang, Xue Cheng Yang, Cheng Xia Hu, Li Jiang Sun, Hai Tao Niu
Pages: 945-951
Published online on: 16 June 2016

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Article

miR-375 exhibits a more effective tumor-suppressor function in laryngeal squamous carcinoma cells by regulating KLF4 expression compared with simple co-transfection of miR-375 and miR-206

Yan Guo, Ran An, Rui Zhao, Yanan Sun, Ming Liu, Linli Tian
Pages: 952-960
Published online on: 03 June 2016

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Article

Emodin induces hepatocellular carcinoma cell apoptosis through MAPK and PI3K/AKT signaling pathways in vitro and in vivo

Wanfu Lin, Maofeng Zhong, Huixia Yin, Yongan Chen, Qingxin Cao, Chen Wang, Changquan Ling
Pages: 961-967
Published online on: 08 June 2016

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Article

Combined treatment with cotylenin A and phenethyl isothiocyanate induces strong antitumor activity mainly through the induction of ferroptotic cell death in human pancreatic cancer cells

Takashi Kasukabe, Yoshio Honma, Junko Okabe-Kado, Yusuke Higuchi, Nobuo Kato, Shunichi Kumakura
Pages: 968-976
Published online on: 10 June 2016

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Article

TGF-β1 promotes the migration and invasion of bladder carcinoma cells by increasing fascin1 expression

Naiwen Zhang, Xiaojun Bi, Yu Zeng, Yuyan Zhu, Zhe Zhang, Yang Liu, Jianfeng Wang, Xuejie Li, Jianbin Bi, Chuize Kong
Pages: 977-983
Published online on: 21 June 2016

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Article

Artesunate attenuates glioma proliferation, migration and invasion by affecting cellular mechanical properties

Shizhong Lian, Ruyi Shi, Xun Huang, Xiaoling Hu, Bin Song, Yinshan Bai, Bin Yang, Jinyao Dong, Zhijie Du, Yanyan Zhang, Junmei Jia, Ning Ma, Geng Guo, Mingyu Wang
Pages: 984-990
Published online on: 02 June 2016

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Article

DT-13 attenuates human lung cancer metastasis via regulating NMIIA activity under hypoxia condition

Xiao-Hui Wei, Sen-Sen Lin, Yang Liu, Ren-Ping Zhao, Ghulam Jilany Khan, Hong-Zhi Du, Ting-Ting Mao, Bo-Yang Yu, Rui-Ming Li, Sheng-Tao Yuan, Li Sun
Pages: 991-999
Published online on: 16 June 2016

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Article

FYN promotes breast cancer progression through epithelial-mesenchymal transition

Ye-Gong Xie, Yue Yu, Li-Kun Hou, Xin Wang, Bin Zhang, Xu-Chen Cao
Pages: 1000-1006
Published online on: 22 June 2016

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Article

miR-493-5p attenuates the invasiveness and tumorigenicity in human breast cancer by targeting FUT4

Lifen Zhao, Xiaobin Feng, Xiaobo Song, Huimin Zhou, Yongfu Zhao, Lei Cheng, Li Jia
Pages: 1007-1015
Published online on: 16 June 2016

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Article

Atorvastatin partially inhibits the epithelial-mesenchymal transition in A549 cells induced by TGF-β1 by attenuating the upregulation of SphK1

Zhiqiang Fan, Handong Jiang, Zili Wang, Jieming Qu
Pages: 1016-1022
Published online on: 22 June 2016

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Article

Nitidine chloride suppresses epithelial-to-mesenchymal transition in osteosarcoma cell migration and invasion through Akt/GSK-3β/Snail signaling pathway

Zhenxiu Cheng, Yinglong Guo, Yubao Yang, Jinqing Kan, Shiyou Dai, Mengfei Helian, Bo Li, Jia Xu, Changying Liu
Pages: 1023-1029
Published online on: 02 June 2016

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Article

Correlation of EGFR Del 19 with Fn14/JAK/STAT signaling molecules in non-small cell lung cancer

Ying Sun, Yong Han, Xiaoping Wang, Wuping Wang, Xuejiao Wang, Miaomiao Wen, Jinghua Xia, Hao Xing, Xiaofei Li, Zhipei Zhang
Pages: 1030-1040
Published online on: 23 June 2016

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Article

Grifolin induces autophagic cell death by inhibiting the Akt/mTOR/S6K pathway in human ovarian cancer cells

Xiaoxia Che, Hong Yan, Hengzi Sun, Samina Dongol, Yilin Wang, Qingtao Lv, Jie Jiang
Pages: 1041-1047
Published online on: 30 May 2016

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Article

High extracellular pressure promotes gastric cancer cell adhesion, invasion, migration and suppresses gastric cancer cell differentiation

Changlei Su, Bomiao Zhang, Wenzhi Liu, Hongqun Zheng, Lingyu Sun, Jinxue Tong, Tian Wang, Xiaofeng Jiang, Hongyan Liang, Li Xue, Qifan Zhang
Pages: 1048-1054
Published online on: 30 May 2016

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Article

LKB1 expression reverses the tumorigenicity of L02 cells

Xiaoyan Liang, Ge Xu, Qing Gao, Xiaohong Tao
Pages: 1055-1061
Published online on: 22 June 2016

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Article

DNA hypomethylation of CD133 promoter is associated with recurrent glioma

Baolan Sun, Zhengqiang Wan, Jianhong Shen, Lanchun Ni, Jian Chen, Ming Cui, Hongbing Ni, Wei Shi, Jinlong Shi
Pages: 1062-1068
Published online on: 16 June 2016

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Article

PMA/IONO affects diffuse large B-cell lymphoma cell growth through upregulation of A20 expression

Wenxiu Yang, Yi Li, Pinhao Li, Lingling Wang
Pages: 1069-1075
Published online on: 22 June 2016

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Article

Identification of reliable reference genes for quantitative gene expression studies in oral squamous cell carcinomas compared to adjacent normal tissues in the F344 rat model

Xinjian Peng, David L. McCormick
Pages: 1076-1084
Published online on: 16 June 2016

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Article

Potential diagnostic value of lncRNA SPRY4-IT1 in hepatocellular carcinoma

Wei Jing, Shanshan Gao, Man Zhu, Ping Luo, Xuan Jing, Hongyan Chai, Jiancheng Tu
Pages: 1085-1092
Published online on: 07 June 2016

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The amino acid-rich elemental diet Elental® preserves lean body mass during chemo- or chemoradiotherapy for esophageal cancer

Takeshi Ishikawa, Tomoyo Yasuda, Toshifumi Doi, Tetsuya Okayama, Naoyuki Sakamoto, Yasuyuki Gen, Osamu Dohi, Naohisa Yoshida, Kazuhiro Kamada, Kazuhiko Uchiyama, Osamu Handa, Tomohisa Takagi, Hideyuki Konishi, Nobuaki Yagi, Satoshi Kokura, Yuji Naito, Yoshito Itoh
Pages: 1093-1100
Published online on: 15 June 2016

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Angiotensin II promotes endometrial cancer cell survival

Magdalena Nowakowska, Zuzanna Matysiak-Burzyńska, Karolina Kowalska, Elżbieta Płuciennik, Kamila Domińska, Agnieszka W. Piastowska-Ciesielska
Pages: 1101-1110
Published online on: 21 June 2016

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MicroRNA-340 promotes the tumor growth of human gastric cancer by inhibiting cyclin G2

Guozhi Yin, Huayou Zhou, Yumo Xue, Bowen Yao, Wei Zhao
Pages: 1111-1118
Published online on: 15 June 2016

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Butyrate-mediated acquisition of chemoresistance by human colon cancer cells

Hyang Ri Kang, Hyeon Gyeom Choi, Chae Kyung Jeon, Soo-Jeong Lim, So Hee Kim
Pages: 1119-1126
Published online on: 27 May 2016

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Combination treatment with proteasome inhibitors and antiestrogens has a synergistic effect mediated by p21WAF1 in estrogen receptor-positive breast cancer

Marie Maynadier, Ilaria Basile, Audrey Gallud, Magali Gary-Bobo, Marcel Garcia
Pages: 1127-1134
Published online on: 14 June 2016

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RIP kinase-mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin-treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Pages: 1135-1142
Published online on: 22 June 2016

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miR-24 promotes the proliferation, migration and invasion in human tongue squamous cell carcinoma by targeting FBXW7

Jingzhu Zhao, Chuanxiang Hu, Jiadong Chi, Jiansen Li, Chen Peng, Xinwei Yun, Dapeng Li, Yang Yu, Yigong Li, Ming Gao, Xiangqian Zheng
Pages: 1143-1149
Published online on: 22 June 2016

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Alternol inhibits the proliferation and induces the differentiation of the mouse melanoma B16F0 cell line

Caixia Wang, Wenjuan Xu, Wenjin Hao, Bingsheng Wang, Qiusheng Zheng
Pages: 1150-1156
Published online on: 02 June 2016

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7-Difluoromethoxyl-5,4'-di-n-octyl genistein inhibits the stem-like characteristics of gastric cancer stem-like cells and reverses the phenotype of epithelial-mesenchymal transition in gastric cancer cells Corrigendum in /10.3892/or.2022.8391

Xiaozheng Cao, Kaiqun Ren, Zhengwei Song, Duo Li, Meifang Quan, Yu Zheng, Jianguo Cao, Wenbin Zeng, Hui Zou
Pages: 1157-1165
Published online on: 02 June 2016

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EGFR and KRAS mutational analysis in a large series of Italian non-small cell lung cancer patients: 2,387 cases from a single center

Riccardo Giannini, Cristiana Lupi, Elisa Sensi, Greta Alì, Agnese Proietti, Laura Boldrini, Adele Servadio, Mirella Giordano, Elisabetta Macerola, Rossella Bruno, Nicla Borrelli, Antonio Chella, Franca Melfi, Marco Lucchi, Alessandro Ribechini, Enrico Vasile, Federico Cappuzzo, Alfredo Mussi, Gabriella Fontanini
Pages: 1166-1172
Published online on: 14 June 2016

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Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo

Chin-Cheng Su, Tsung-Lang Chiu
Pages: 1173-1179
Published online on: 07 June 2016

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Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A in MCF-7/adriamycin cells

Fen Cai, Liang Zhang, Xiangling Xiao, Chao Duan, Qiuyue Huang, Chunsheng Fan, Jian Li, Xuewen Liu, Shan Li, Ying Liu
Pages: 1180-1186
Published online on: 22 June 2016

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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