|
1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ryan DP, Hong TS and Bardeesy N:
Pancreatic adenocarcinoma. N Engl J Med. 371:1039–1049. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Quaresma M, Coleman MP and Rachet B:
40-year trends in an index of survival for all cancers combined and
survival adjusted for age and sex for each cancer in England and
Wales, 1971–2011: A population-based study. Lancet. 385:1206–1218.
2015. View Article : Google Scholar
|
|
5
|
Konstantinidis IT, Warshaw AL, Allen JN,
Blaszkowsky LS, Castillo CF, Deshpande V, Hong TS, Kwak EL, Lauwers
GY, Ryan DP, et al: Pancreatic ductal adenocarcinoma: Is there a
survival difference for R1 resections versus locally advanced
unresectable tumors? What is a 'true' R0 resection? Ann Surg.
257:731–736. 2013. View Article : Google Scholar
|
|
6
|
Iacobuzio-Donahue CA, Fu B, Yachida S, Luo
M, Abe H, Henderson CM, Vilardell F, Wang Z, Keller JW, Banerjee P,
et al: DPC4 gene status of the primary carcinoma correlates with
patterns of failure in patients with pancreatic cancer. J Clin
Oncol. 27:1806–1813. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Kishimoto T, Akira S, Narazaki M and Taga
T: Interleukin-6 family of cytokines and gp130. Blood.
86:1243–1254. 1995.PubMed/NCBI
|
|
8
|
Alisoltani A, Fallahi H, Ebrahimi M,
Ebrahimi M and Ebrahimie E: Prediction of potential cancer-risk
regions based on transcriptome data: Towards a comprehensive view.
PLoS One. 9:e963202014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Salm F, Dimitrova V, von Bueren AO, Ćwiek
P, Rehrauer H, Djonov V, Anderle P and Arcaro A: The
phosphoinositide 3-kinase p110α isoform regulates leukemia
inhibitory factor receptor expression via c-Myc and miR-125b to
promote cell proliferation in medulloblastoma. PLoS One.
10:e01239582015. View Article : Google Scholar
|
|
10
|
Liu SC, Tsang NM, Chiang WC, Chang KP,
Hsueh C, Liang Y, Juang JL, Chow KP and Chang YS: Leukemia
inhibitory factor promotes nasopharyngeal carcinoma progression and
radioresistance. J Clin Invest. 123:5269–5283. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Chen D, Sun Y, Wei Y, Zhang P, Rezaeian
AH, Teruya-Feldstein J, Gupta S, Liang H, Lin HK, Hung MC, et al:
LIFR is a breast cancer metastasis suppressor upstream of the
Hippo-YAP pathway and a prognostic marker. Nat Med. 18:1511–1517.
2012. View
Article : Google Scholar : PubMed/NCBI
|
|
12
|
Tan X and Chen M: MYLK and MYL9 expression
in non-small cell lung cancer identified by bioinformatics analysis
of public expression data. Tumour Biol. 12:12189–12200. 2014.
View Article : Google Scholar
|
|
13
|
Luo Q, Zhang Y, Wang N, Jin G, Jin H, Gu
D, Tao X, Huo X, Ge T, Cong W, et al: Leukemia inhibitory factor
receptor is a novel immunomarker in distinction of
well-differentiated HCC from dysplastic nodules. Oncotarget.
6:6989–6999. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Luo Q, Wang C, Jin G, Gu D, Wang N, Song
J, Jin H, Hu F, Zhang Y, Ge T, et al: LIFR functions as a
metastasis suppressor in hepatocellular carcinoma by negatively
regulating phosphoinositide 3-kinase/AKT pathway. Carcinogenesis.
36:1201–1212. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Seewoo V, Yang W, Du H, Wang J, Lin A,
Shen B, Peng C, Li H and Qiu W: The different induction mechanisms
of growth arrest DNA damage inducible gene 45 β in human hepatoma
cell lines. Chemotherapy. 58:165–174. 2012. View Article : Google Scholar
|
|
16
|
Hong X, Bu L, Wang Y, Xu J, Wu J, Huang Y,
Liu J, Suo H, Yang L, Shi Y, et al: Increases in the risk of
cognitive impairment and alterations of cerebral β-amyloid
metabolism in mouse model of heart failure. PLoS One. 8:e638292013.
View Article : Google Scholar
|
|
17
|
Gearing DP, Thut CJ, VandeBos T, Gimpel
SD, Delaney PB, King J, Price V, Cosman D and Beckmann MP: Leukemia
inhibitory factor receptor is structurally related to the IL-6
signal transducer, gp130. EMBO J. 10:2839–2848. 1991.PubMed/NCBI
|
|
18
|
Taga T, Narazaki M, Yasukawa K, Saito T,
Miki D, Hamaguchi M, Davis S, Shoyab M, Yancopoulos GD and
Kishimoto T: Functional inhibition of hematopoietic and
neurotrophic cytokines by blocking the interleukin 6 signal
transducer gp130. Proc Natl Acad Sci USA. 89:10998–11001. 1992.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Nandy SB, Arumugam A, Subramani R, Pedroza
D, Hernandez K, Saltzstein E and Lakshmanaswamy R: MicroRNA-125a
influences breast cancer stem cells by targeting leukemia
inhibitory factor receptor which regulates the Hippo signaling
pathway. Oncotarget. 6:17366–17378. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Li J, Ma Q, Liu H, Guo K, Li F, Li W, Han
L, Wang F and Wu E: Relationship between neural alteration and
perineural invasion in pancreatic cancer patients with
hyperglycemia. PLoS One. 6:e173852011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Nakao A, Harada A, Nonami T, Kaneko T and
Takagi H: Clinical significance of carcinoma invasion of the
extrapancreatic nerve plexus in pancreatic cancer. Pancreas.
12:357–361. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Dai H, Li R, Wheeler T, Ozen M, Ittmann M,
Anderson M, Wang Y, Rowley D, Younes M and Ayala GE: Enhanced
survival in perineural invasion of pancreatic cancer: An in vitro
approach. Hum Pathol. 38:299–307. 2007. View Article : Google Scholar
|
|
23
|
Keleg S, Büchler P, Ludwig R, Büchler MW
and Friess H: Invasion and metastasis in pancreatic cancer. Mol
Cancer. 2:142003. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Shimada K, Nara S, Esaki M, Sakamoto Y,
Kosuge T and Hiraoka N: Intrapancreatic nerve invasion as a
predictor for recurrence after pancreaticoduodenectomy in patients
with invasive ductal carcinoma of the pancreas. Pancreas.
40:464–468. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Takahashi H, Ohigashi H, Ishikawa O, Gotoh
K, Yamada T, Nagata S, Tomita Y, Eguchi H, Doki Y and Yano M:
Perineural invasion and lymph node involvement as indicators of
surgical outcome and pattern of recurrence in the setting of
preoperative gemcitabine-based chemoradiation therapy for
resectable pancreatic cancer. Ann Surg. 255:95–102. 2012.
View Article : Google Scholar
|
|
26
|
Pasquier J, Abu-Kaoud N, Al Thani H and
Rafii A: Epithelial to mesenchymal transition in a clinical
perspective. J Oncol. 2015:7921822015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Liu X, Yun F, Shi L, Li ZH, Luo NR and Jia
YF: Roles of signaling pathways in the epithelial-mesenchymal
transition in cancer. Asian Pac J Cancer Prev. 16:6201–6206. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Cohen EN, Gao H, Anfossi S, Mego M, Reddy
NG, Debeb B, Giordano A, Tin S, Wu Q, Garza RJ, et al: Inflammation
mediated metastasis: Immune induced epithelial-to-mesenchymal
transition in inflammatory breast cancer cells. PLoS One.
10:e01327102015. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Lee JM, Dedhar S, Kalluri R and Thompson
EW: The epithelial-mesenchymal transition: New insights in
signaling, development, and disease. J Cell Biol. 172:973–981.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Domínguez D, Montserrat-Sentís B,
Virgós-Soler A, Guaita S, Grueso J, Porta M, Puig I, Baulida J,
Francí C and García de Herreros A: Phosphorylation regulates the
subcellular location and activity of the snail transcriptional
repressor. Mol Cell Biol. 23:5078–5089. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Rosivatz E, Becker KF, Kremmer E, Schott
C, Blechschmidt K, Höfler H and Sarbia M: Expression and nuclear
localization of Snail, an E-cadherin repressor, in adenocarcinomas
of the upper gastrointestinal tract. Virchows Arch. 448:277–287.
2006. View Article : Google Scholar
|
|
32
|
Brabletz T, Jung A, Reu S, Porzner M,
Hlubek F, Kunz- Schughart LA, Knuechel R and Kirchner T: Variable
beta-catenin expression in colorectal cancers indicates tumor
progression driven by the tumor environment. Proc Natl Acad Sci
USA. 98:10356–10361. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Savagner P, Yamada KM and Thiery JP: The
zinc-finger protein slug causes desmosome dissociation, an initial
and necessary step for growth factor-induced epithelial-mesenchymal
transition. J Cell Biol. 137:1403–1419. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
MacDonald BT, Tamai K and He X:
Wnt/beta-catenin signaling: Components, mechanisms, and diseases.
Dev Cell. 17:9–26. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Shah AN, Summy JM, Zhang J, Park SI,
Parikh NU and Gallick GE: Development and characterization of
gemcitabine-resistant pancreatic tumor cells. Ann Surg Oncol.
14:3629–3637. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Wang Z, Li Y, Kong D, Banerjee S, Ahmad A,
Azmi AS, Ali S, Abbruzzese JL, Gallick GE and Sarkar FH:
Acquisition of epithelial-mesenchymal transition phenotype of
gemcitabine-resistant pancreatic cancer cells is linked with
activation of the notch signaling pathway. Cancer Res.
69:2400–2407. 2009. View Article : Google Scholar : PubMed/NCBI
|
