|
1
|
Demierre MF and Merlino G: Chemoprevention
of melanoma. Curr Oncol Rep. 6:406–413. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Friedman AA, Amzallag A, Pruteanu-Malinici
I, Baniya S, Cooper ZA, Piris A, Hargreaves L, Igras V, Frederick
DT, Lawrence DP, et al: Landscape of targeted anti-cancer drug
synergies in melanoma identifies a novel BRAF-VEGFR/PDGFR
combination treatment. PLoS One. 10:e01403102015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Achiwa Y, Hasegawa K and Udagawa Y: Effect
of ursolic acid on MAPK in cyclin D1 signaling and RING-type E3
ligase (SCF E3s) in two endometrial cancer cell lines. Nutr Cancer.
65:1026–1033. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ascierto PA, Atkins M, Bifulco C, Botti G,
Cochran A, Davies M, Demaria S, Dummer R, Ferrone S, Formenti S, et
al: Future perspectives in melanoma research: Meeting report from
the 'Melanoma Bridge': Napoli, December 3rd–6th 2014. J Transl Med.
13:3742015. View Article : Google Scholar
|
|
5
|
Aijaz S, D'Atri F, Citi S, Balda MS and
Matter K: Binding of GEF-H1 to the tight junction-associated
adaptor cingulin results in inhibition of Rho signaling and G1/S
phase transition. Dev Cell. 8:777–786. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Hiyoshi H, Okada R, Matsuda S, Gotoh K,
Akeda Y, Iida T and Kodama T: Interaction between the type III
effector VopO and GEF-H1 activates the RhoA-ROCK pathway. PLoS
Pathog. 11:e10046942015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Song EH, Oh W, Ulu A, Carr HS, Zuo Y and
Frost JA: Acetylation of the RhoA GEF Net1A controls its
subcellular localization and activity. J Cell Sci. 128:913–922.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Guilluy C, Swaminathan V, Garcia-Mata R,
O'Brien ET, Superfine R and Burridge K: The Rho GEFs LARG and
GEF-H1 regulate the mechanical response to force on integrins. Nat
Cell Biol. 13:722–727. 2011. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
Huynh TK, Meeus P, Cassier P, Bouché O,
Lardière-Deguelte S, Adenis A, André T, Mancini J, Collard O,
Montemurro M, et al: Primary localized rectal/pararectal
gastrointestinal stromal tumors: Results of surgical and multimodal
therapy from the French Sarcoma group. BMC Cancer. 14:1562014.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Ridgway LD, Wetzel MD, Ngo JA,
Erdreich-Epstein A and Marchetti D: Heparanase-induced GEF-H1
signaling regulates the cytoskeletal dynamics of brain metastatic
breast cancer cells. Mol Cancer Res. 10:689–702. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Guo F, Tang J, Zhou Z, Dou Y, Van
Lonkhuyzen D, Gao C and Huan J: GEF-H1-RhoA signaling pathway
mediates LPS-induced NF-κB transactivation and IL-8 synthesis in
endothelial cells. Mol Immunol. 50:98–107. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Ridgway LD, Wetzel MD and Marchetti D:
Modulation of GEF-H1 induced signaling by heparanase in brain
metastatic melanoma cells. J Cell Biochem. 111:1299–1309. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Cullis J, Meiri D, Sandi MJ, Radulovich N,
Kent OA, Medrano M, Mokady D, Normand J, Larose J, Marcotte R, et
al: The RhoGEF GEF-H1 is required for oncogenic RAS signaling via
KSR-1. Cancer Cell. 25:181–195. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Gawlak G, Tian Y, O'Donnell JJ III, Tian
X, Birukova AA and Birukov KG: Paxillin mediates stretch-induced
Rho signaling and endothelial permeability via assembly of
paxillin-p42/44MAPK-GEF-H1 complex. FASEB J. 28:3249–3260. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Huang IH, Hsiao CT, Wu JC, Shen RF, Liu
CY, Wang YK, Chen YC, Huang CM, del Álamo JC, Chang ZF, et al:
GEF-H1 controls focal adhesion signaling that regulates mesenchymal
stem cell lineage commitment. J Cell Sci. 127:4186–4200. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kakiashvili E, Dan Q, Vandermeer M, Zhang
Y, Waheed F, Pham M and Szászi K: The epidermal growth factor
receptor mediates tumor necrosis factor-alpha-induced activation of
the ERK/GEF-H1/RhoA pathway in tubular epithelium. J Biol Chem.
286:9268–9279. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kakiashvili E, Speight P, Waheed F, Seth
R, Lodyga M, Tanimura S, Kohno M, Rotstein OD, Kapus A and Szászi
K: GEF-H1 mediates tumor necrosis factor-alpha-induced Rho
activation and myosin phosphorylation: Role in the regulation of
tubular paracellular permeability. J Biol Chem. 284:11454–11466.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Mizuarai S, Yamanaka K and Kotani H:
Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide
exchange factor-H1 for RhoA, resulting in accelerated cell
proliferation in tumor cells. Cancer Res. 66:6319–6326. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Biondini M, Duclos G, Meyer-Schaller N,
Silberzan P, Camonis J and Parrini MC: RalB regulates
contractility-driven cancer dissemination upon TGFβ stimulation via
the RhoGEF GEF-H1. Sci Rep. 5:117592015. View Article : Google Scholar
|
|
20
|
Liao YC, Ruan JW, Lua I, Li MH, Chen WL,
Wang JR, Kao RH and Chen JH: Overexpressed hPTTG1 promotes breast
cancer cell invasion and metastasis by regulating GEF-H1/RhoA
signalling. Oncogene. 31:3086–3097. 2012. View Article : Google Scholar :
|
|
21
|
Krendel M, Zenke FT and Bokoch GM:
Nucleotide exchange factor GEF-H1 mediates cross-talk between
microtubules and the actin cytoskeleton. Nat Cell Biol. 4:294–301.
2002. View
Article : Google Scholar : PubMed/NCBI
|
|
22
|
Matsuzawa T, Kuwae A, Yoshida S, Sasakawa
C and Abe A: Enteropathogenic Escherichia coli activates the RhoA
signaling pathway via the stimulation of GEF-H1. EMBO J.
23:3570–3582. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ren Y, Li R, Zheng Y and Busch H: Cloning
and characterization of GEF-H1, a microtubule-associated guanine
nucleotide exchange factor for Rac and Rho GTPases. J Biol Chem.
273:34954–34960. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Aznar S, Fernández-Valerón P, Espina C and
Lacal JC: Rho GTPases: Potential candidates for anticancer therapy.
Cancer Lett. 206:181–191. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Erhard F, Haas J, Lieber D, Malterer G,
Jaskiewicz L, Zavolan M, Dölken L and Zimmer R: Widespread context
dependency of microRNA-mediated regulation. Genome Res. 24:906–919.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Suzuki HI, Mihira H, Watabe T, Sugimoto K
and Miyazono K: Widespread inference of weighted microRNA-mediated
gene regulation in cancer transcriptome analysis. Nucleic Acids
Res. 41:e622013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Krol J, Loedige I and Filipowicz W: The
widespread regulation of microRNA biogenesis, function and decay.
Nat Rev Genet. 11:597–610. 2010.PubMed/NCBI
|
|
28
|
Bennett PE, Bemis L, Norris DA and
Shellman YG: miR in melanoma development: miRNAs and acquired
hallmarks of cancer in melanoma. Physiol Genomics. 45:1049–1059.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Müller DW and Bosserhoff AK: Integrin beta
3 expression is regulated by let-7a miRNA in malignant melanoma.
Oncogene. 27:6698–6706. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Chen J, Feilotter HE, Paré GC, Zhang X,
Pemberton JG, Garady C, Lai D, Yang X and Tron VA: MicroRNA-193b
represses cell proliferation and regulates cyclin D1 in melanoma.
Am J Pathol. 176:2520–2529. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Dar AA, Majid S, de Semir D, Nosrati M,
Bezrookove V and Kashani-Sabet M: miRNA-205 suppresses melanoma
cell proliferation and induces senescence via regulation of E2F1
protein. J Biol Chem. 286:16606–16614. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Noguchi S, Iwasaki J, Kumazaki M, Mori T,
Maruo K, Sakai H, Yamada N, Shimada K, Naoe T, Kitade Y, et al:
Chemically modified synthetic microRNA-205 inhibits the growth of
melanoma cells in vitro and in vivo. Mol Ther. 21:1204–1211. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Meng Z, Fu X, Chen X, Zeng S, Tian Y, Jove
R, Xu R and Huang W: miR-194 is a marker of hepatic epithelial
cells and suppresses metastasis of liver cancer cells in mice.
Hepatology. 52:2148–2157. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Braun CJ, Zhang X, Savelyeva I, Wolff S,
Moll UM, Schepeler T, Ørntoft TF, Andersen CL and Dobbelstein M:
p53-Responsive micrornas 192 and 215 are capable of inducing cell
cycle arrest. Cancer Res. 68:10094–10104. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Song Y, Zhao F, Wang Z, Liu Z, Chiang Y,
Xu Y, Gao P and Xu H: Inverse association between miR-194
expression and tumor invasion in gastric cancer. Ann Surg Oncol.
19(Suppl 3): S509–S517. 2012. View Article : Google Scholar
|
|
36
|
Kemper K, Krijgsman O,
Cornelissen-Steijger P, Shahrabi A, Weeber F, Song JY, Kuilman T,
Vis DJ, Wessels LF, Voest EE, et al: Intra- and inter-tumor
heterogeneity in a vemurafenib-resistant melanoma patient and
derived xenografts. EMBO Mol Med. 7:1104–1118. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Feng J, Wang K, Liu X, Chen S and Chen J:
The quantification of tomato microRNAs response to viral infection
by stem-loop real-time RT-PCR. Gene. 437:14–21. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Chen C, Ridzon DA, Broomer AJ, Zhou Z, Lee
DH, Nguyen JT, Barbisin M, Xu NL, Mahuvakar VR, Andersen MR, et al:
Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic
Acids Res. 33:e1792005. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Pfaffl MW: A new mathematical model for
relative quantification in real-time RT-PCR. Nucleic Acids Res.
29:e452001. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Yang TS, Yang XH, Wang XD, Wang YL, Zhou B
and Song ZS: MiR-214 regulate gastric cancer cell proliferation,
migration and invasion by targeting PTEN. Cancer Cell Int.
13:682013. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Patel D and Chaudhary J: Increased
expression of bHLH transcription factor E2A (TCF3) in prostate
cancer promotes proliferation and confers resistance to doxorubicin
induced apoptosis. Biochem Biophys Res Commun. 422:146–151. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Chen X, Wang Y, Zang W, Du Y, Li M and
Zhao G: miR-194 targets RBX1 gene to modulate proliferation and
migration of gastric cancer cells. Tumour Biol. 36:2393–2401. 2015.
View Article : Google Scholar
|
|
43
|
Balch CM, Gershenwald JE, Soong SJ,
Thompson JF, Atkins MB, Byrd DR, Buzaid AC, Cochran AJ, Coit DG,
Ding S, et al: Final version of 2009 AJCC melanoma staging and
classification. J Clin Oncol. 27:6199–6206. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Wells CM, Whale AD, Parsons M, Masters JR
and Jones GE: PAK4: A pluripotent kinase that regulates prostate
cancer cell adhesion. J Cell Sci. 123:1663–1673. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Basati G, Razavi AE, Pakzad I and Malayeri
FA: Circulating levels of the miRNAs, miR-194, and miR-29b, as
clinically useful biomarkers for colorectal cancer. Tumour Biol.
37:1781–1788. 2016. View Article : Google Scholar
|
|
46
|
Wang B, Shen ZL, Gao ZD, Zhao G, Wang CY,
Yang Y, Zhang JZ, Yan YC, Shen C, Jiang KW, et al: MiR-194,
commonly repressed in colorectal cancer, suppresses tumor growth by
regulating the MAP4K4/c-Jun/MDM2 signaling pathway. Cell Cycle.
14:1046–1058. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Wu X, Liu T, Fang O, Leach LJ, Hu X and
Luo Z: miR-194 suppresses metastasis of non-small cell lung cancer
through regulating expression of BMP1 and p27kip1.
Oncogene. 33:1506–1514. 2014. View Article : Google Scholar
|
|
48
|
Dong P, Kaneuchi M, Watari H, Hamada J,
Sudo S, Ju J and Sakuragi N: MicroRNA-194 inhibits epithelial to
mesenchymal transition of endometrial cancer cells by targeting
oncogene BMI-1. Mol Cancer. 10:992011. View Article : Google Scholar : PubMed/NCBI
|
