1
|
Liu YQ, Zhao FJ, Chen WQ, et al: An
analysis of incidence and mortality of leukemia in China, 2009.
China Cancer. 7:528–534. 2013.
|
2
|
Muto T, Sashida G, Oshima M and Iwama A:
Mutations of epigenetic regulator genes and myeloid malignancies.
Rinsho Ketsueki. 56:2287–2294. 2015.(In Japanese). PubMed/NCBI
|
3
|
Chalei V, Sansom SN, Kong L, Lee S,
Montiel JF, Vance KW and Ponting CP: The long non-coding RNA Dali
is an epigenetic regulator of neural differentiation. eLife.
3:e045302014. View Article : Google Scholar : PubMed/NCBI
|
4
|
Lee DH, Singh P, Tsai SY, Oates N, Spalla
A, Spalla C, Brown L, Rivas G, Larson G, Rauch TA, et al:
CTCF-dependent chromatin bias constitutes transient epigenetic
memory of the mother at the H19-Igf2 imprinting control region in
prospermatogonia. PLoS Genet. 6:e10012242010. View Article : Google Scholar : PubMed/NCBI
|
5
|
Haemmerle M and Gutschner T: Long
non-coding RNAs in cancer and development: Where do we go from
here? Int J Mol Sci. 16:1395–1405. 2015. View Article : Google Scholar : PubMed/NCBI
|
6
|
Guttman M, Donaghey J, Carey BW, Garber M,
Grenier JK, Munson G, Young G, Lucas AB, Ach R, Bruhn L, et al:
lincRNAs act in the circuitry controlling pluripotency and
differentiation. Nature. 477:295–300. 2011. View Article : Google Scholar : PubMed/NCBI
|
7
|
Li X, Wu Z, Fu X and Han W: lncRNAs:
Insights into their function and mechanics in underlying disorders.
Mutat Res Rev Mutat Res. 762:1–21. 2014. View Article : Google Scholar : PubMed/NCBI
|
8
|
Rinn JL, Kertesz M, Wang JK, Squazzo SL,
Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, et
al: Functional demarcation of active and silent chromatin domains
in human HOX loci by noncoding RNAs. Cell. 129:1311–1323. 2007.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Gupta RA, Shah N, Wang KC, Kim J, Horlings
HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, et al: Long
non-coding RNA HOTAIR reprograms chromatin state to promote cancer
metastasis. Nature. 464:1071–1076. 2010. View Article : Google Scholar : PubMed/NCBI
|
10
|
Bhan A, Hussain I, Ansari KI, Kasiri S,
Bashyal A and Mandal SS: Antisense transcript long noncoding RNA
(lncRNA) HOTAIR is transcriptionally induced by estradiol. J Mol
Biol. 425:3707–3722. 2013. View Article : Google Scholar : PubMed/NCBI
|
11
|
Chisholm KM, Wan Y, Li R, Montgomery KD,
Chang HY and West RB: Detection of long non-coding RNA in archival
tissue: Correlation with polycomb protein expression in primary and
metastatic breast carcinoma. PLoS One. 7:e479982012. View Article : Google Scholar : PubMed/NCBI
|
12
|
Wu ZH, Wang XL, Tang HM, Jiang T, Chen J,
Lu S, Qiu GQ, Peng ZH and Yan DW: Long non-coding RNA HOTAIR is a
powerful predictor of metastasis and poor prognosis and is
associated with epithelial-mesenchymal transition in colon cancer.
Oncol Rep. 32:395–402. 2014.PubMed/NCBI
|
13
|
Ye P, Wang T, Liu WH, Li XC, Tang LJ and
Tian FZ: Enhancing HOTAIR/MiR-10b drives normal liver stem cells
toward a tendency to malignant transformation through inducing
epithelial-to-mesenchymal transition. Rejuvenation Res. 18:332–340.
2015. View Article : Google Scholar : PubMed/NCBI
|
14
|
Zhuang Y, Wang X, Nguyen HT, Zhuo Y, Cui
X, Fewell C, Flemington EK and Shan B: Induction of long intergenic
non-coding RNA HOTAIR in lung cancer cells by type I collagen. J
Hematol Oncol. 6:352013. View Article : Google Scholar : PubMed/NCBI
|
15
|
Kim K, Jutooru I, Chadalapaka G, Johnson
G, Frank J, Burghardt R, Kim S and Safe S: HOTAIR is a negative
prognostic factor and exhibits pro-oncogenic activity in pancreatic
cancer. Oncogene. 32:1616–1625. 2013. View Article : Google Scholar : PubMed/NCBI
|
16
|
Nie Y, Liu X, Qu S, Song E, Zou H and Gong
C: Long non-coding RNA HOTAIR is an independent prognostic marker
for nasopharyngeal carcinoma progression and survival. Cancer Sci.
104:458–464. 2013. View Article : Google Scholar : PubMed/NCBI
|
17
|
Nakagawa T, Endo H, Yokoyama M, Abe J,
Tamai K, Tanaka N, Sato I, Takahashi S, Kondo T and Satoh K: Large
noncoding RNA HOTAIR enhances aggressive biological behavior and is
associated with short disease-free survival in human non-small cell
lung cancer. Biochem Biophys Res Commun. 436:319–324. 2013.
View Article : Google Scholar : PubMed/NCBI
|
18
|
Simon JA and Lange CA: Roles of the EZH2
histone methyltransferase in cancer epigenetics. Mutat Res.
647:21–29. 2008. View Article : Google Scholar : PubMed/NCBI
|
19
|
Lee MG, Wynder C, Cooch N and Shiekhattar
R: An essential role for CoREST in nucleosomal histone 3 lysine 4
demethylation. Nature. 437:432–435. 2005.PubMed/NCBI
|
20
|
Shi YJ, Matson C, Lan F, Iwase S, Baba T
and Shi Y: Regulation of LSD1 histone demethylase activity by its
associated factors. Mol Cell. 19:857–864. 2005. View Article : Google Scholar : PubMed/NCBI
|
21
|
Shi Y, Lan F, Matson C, Mulligan P,
Whetstine JR, Cole PA, Casero RA and Shi Y: Histone demethylation
mediated by the nuclear amine oxidase homolog LSD1. Cell.
119:941–953. 2004. View Article : Google Scholar : PubMed/NCBI
|
22
|
Tsai MC, Manor O, Wan Y, Mosammaparast N,
Wang JK, Lan F, Shi Y, Segal E and Chang HY: Long noncoding RNA as
modular scaffold of histone modification complexes. Science.
329:689–693. 2010. View Article : Google Scholar : PubMed/NCBI
|
23
|
Döhner H, Estey EH, Amadori S, Appelbaum
FR, Büchner T, Burnett AK, Dombret H, Fenaux P, Grimwade D, Larson
RA, et al: European LeukemiaNet: Diagnosis and management of acute
myeloid leukemia in adults: Recommendations from an international
expert panel, on behalf of the European LeukemiaNet. Blood.
115:453–474. 2010. View Article : Google Scholar : PubMed/NCBI
|
24
|
Kogo R, Shimamura T, Mimori K, Kawahara K,
Imoto S, Sudo T, Tanaka F, Shibata K, Suzuki A, Komune S, et al:
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin
modification and is associated with poor prognosis in colorectal
cancers. Cancer Res. 71:6320–6326. 2011. View Article : Google Scholar : PubMed/NCBI
|
25
|
Wu S, Zheng C, Chen S, Cai X, Shi Y, Lin B
and Chen Y: Overexpression of long non-coding RNA HOTAIR predicts a
poor prognosis in patients with acute myeloid leukemia. Oncol Lett.
10:2410–2414. 2015.PubMed/NCBI
|
26
|
Hao S and Shao Z: HOTAIR is upregulated in
acute myeloid leukemia and that indicates a poor prognosis. Int J
Clin Exp Pathol. 8:7223–7228. 2015.PubMed/NCBI
|
27
|
Ku M, Koche RP, Rheinbay E, Mendenhall EM,
Endoh M, Mikkelsen TS, Presser A, Nusbaum C, Xie X, Chi AS, et al:
Genomewide analysis of PRC1 and PRC2 occupancy identifies two
classes of bivalent domains. PLoS Genet. 4:e10002422008. View Article : Google Scholar : PubMed/NCBI
|
28
|
Varambally S, Dhanasekaran SM, Zhou M,
Barrette TR, Kumar-Sinha C, Sanda MG, Ghosh D, Pienta KJ, Sewalt
RG, Otte AP, et al: The polycomb group protein EZH2 is involved in
progression of prostate cancer. Nature. 419:624–629. 2002.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Kleer CG, Cao Q, Varambally S, Shen R, Ota
I, Tomlins SA, Ghosh D, Sewalt RG, Otte AP, Hayes DF, et al: EZH2
is a marker of aggressive breast cancer and promotes neoplastic
transformation of breast epithelial cells. Proc Natl Acad Sci USA.
100:11606–11611. 2003. View Article : Google Scholar : PubMed/NCBI
|
30
|
Collett K, Eide GE, Arnes J, Stefansson
IM, Eide J, Braaten A, Aas T, Otte AP and Akslen LA: Expression of
enhancer of zeste homologue 2 is significantly associated with
increased tumor cell proliferation and is a marker of aggressive
breast cancer. Clin Cancer Res. 12:1168–1174. 2006. View Article : Google Scholar : PubMed/NCBI
|
31
|
Fujii S, Tokita K, Wada N, Ito K, Yamauchi
C, Ito Y and Ochiai A: MEK-ERK pathway regulates EZH2
overexpression in association with aggressive breast cancer
subtypes. Oncogene. 30:4118–4128. 2011. View Article : Google Scholar : PubMed/NCBI
|
32
|
Bracken AP, Pasini D, Capra M, Prosperini
E and Colli E K: EZH2 is downstream of the pRB-E2F pathway,
essential for proliferation and amplified in cancer. EMBO J.
22:5323–5335. 2003. View Article : Google Scholar : PubMed/NCBI
|
33
|
Kunderfranco P, Mello-Grand M, Cangemi R,
Pellini S, Mensah A, Albertini V, Malek A, Chiorino G, Catapano CV
and Carbone GM: ETS transcription factors control transcription of
EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1
in prostate cancer. PLoS One. 5:e105472010. View Article : Google Scholar : PubMed/NCBI
|
34
|
Koh CM, Iwata T, Zheng Q, Bethel C,
Yegnasubramanian S and De Marzo AM: Myc enforces overexpression of
EZH2 in early prostatic neoplasia via transcriptional and
post-transcriptional mechanisms. Oncotarget. 2:669–683. 2011.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Richter GH, Plehm S, Fasan A, Rössler S,
Unland R, Bennani-Baiti IM, Hotfilder M, Löwel D, von Luettichau I,
Mossbrugger I, et al: EZH2 is a mediator of EWS/FLI1 driven tumor
growth and metastasis blocking endothelial and neuro-ectodermal
differentiation. Proc Natl Acad Sci USA. 106:5324–5329. 2009.
View Article : Google Scholar : PubMed/NCBI
|
36
|
Ntziachristos P, Tsirigos A, Van
Vlierberghe P, Nedjic J, Trimarchi T, Flaherty MS, Ferres-Marco D,
da Ros V, Tang Z, Siegle J, et al: Genetic inactivation of the
polycomb repressive complex 2 in T cell acute lymphoblastic
leukemia. Nat Med. 18:298–301. 2012. View
Article : Google Scholar : PubMed/NCBI
|
37
|
Zhang J, Ding L, Holmfeldt L, Wu G,
Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, et
al: The genetic basis of early T-cell precursor acute lymphoblastic
leukaemia. Nature. 481:157–163. 2012. View Article : Google Scholar : PubMed/NCBI
|
38
|
Metzger E, Wissmann M, Yin N, Müller JM,
Schneider R, Peters AH, Günther T, Buettner R and Schüle R: LSD1
demethylates repressive histone marks to promote
androgen-receptor-dependent transcription. Nature. 437:436–439.
2005.PubMed/NCBI
|
39
|
Lim S, Janzer A, Becker A, Zimmer A,
Schüle R, Buettner R and Kirfel J: Lysine-specific demethylase 1
(LSD1) is highly expressed in ER-negative breast cancers and a
biomarker predicting aggressive biology. Carcinogenesis.
31:512–520. 2010. View Article : Google Scholar : PubMed/NCBI
|
40
|
Lv T, Yuan D, Miao X, Lv Y, Zhan P, Shen X
and Song Y: Over-expression of LSD1 promotes proliferation,
migration and invasion in non-small cell lung cancer. PLoS One.
7:e350652012. View Article : Google Scholar : PubMed/NCBI
|
41
|
Chen C, Zhao M, Yin N, He B, Wang B, Yuan
Y, Yu F, Hu J, Yin B and Lu Q: Abnormal histone acetylation and
methylation levels in esophageal squamous cell carcinomas. Cancer
Invest. 29:548–556. 2011. View Article : Google Scholar : PubMed/NCBI
|
42
|
Yokoyama A, Takezawa S, Schüle R, Kitagawa
H and Kato S: Transrepressive function of TLX requires the histone
demethylase LSD1. Mol Cell Biol. 28:3995–4003. 2008. View Article : Google Scholar : PubMed/NCBI
|
43
|
Bestor TH: The DNA methyltransferases of
mammals. Hum Mol Genet. 9:2395–2402. 2000. View Article : Google Scholar : PubMed/NCBI
|
44
|
Chedin F, Lieber MR and Hsieh CL: The DNA
methyltransferase-like protein DNMT3L stimulates de novo
methylation by Dnmt3a. Proc Natl Acad Sci USA. 99:16916–16921.
2002. View Article : Google Scholar : PubMed/NCBI
|
45
|
Chen T and Li E: Establishment and
maintenance of DNA methylation patterns in mammals. Curr Top
Microbiol Immunol. 301:179–201. 2006.PubMed/NCBI
|
46
|
Gowher H, Liebert K, Hermann A, Xu G and
Jeltsch A: Mechanism of stimulation of catalytic activity of Dnmt3A
and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L. J Biol
Chem. 280:13341–13348. 2005. View Article : Google Scholar : PubMed/NCBI
|
47
|
Margot JB, Cardoso MC and Leonhardt H:
Mammalian DNA methyltransferases show different subnuclear
distributions. J Cell Biochem. 83:373–379. 2001. View Article : Google Scholar : PubMed/NCBI
|
48
|
Robaina MC, Mazzoccoli L, Arruda VO, Reis
FR, Apa AG, de Rezende LM and Klumb CE: Deregulation of DNMT1,
DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution
for disease pathogenesis. Exp Mol Pathol. 98:200–207. 2015.
View Article : Google Scholar : PubMed/NCBI
|
49
|
Pathania R, Ramachandran S, Elangovan S,
Padia R, Yang P, Cinghu S, Veeranan-Karmegam R, Arjunan P,
Gnana-Prakasam JP, Sadanand F, et al: DNMT1 is essential for
mammary and cancer stem cell maintenance and tumorigenesis. Nat
Commun. 6:69102015. View Article : Google Scholar : PubMed/NCBI
|
50
|
Viré E, Brenner C, Deplus R, Blanchon L,
Fraga M, Didelot C, Morey L, Van Eynde A, Bernard D, Vanderwinden
JM, et al: The Polycomb group protein EZH2 directly controls DNA
methylation. Nature. 439:871–874. 2006. View Article : Google Scholar : PubMed/NCBI
|
51
|
Wang J, Hevi S, Kurash JK, Lei H, Gay F,
Bajko J, Su H, Sun W, Chang H, Xu G, et al: The lysine demethylase
LSD1 (KDM1) is required for maintenance of global DNA methylation.
Nat Genet. 41:125–129. 2009. View
Article : Google Scholar : PubMed/NCBI
|