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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2016 Volume 36 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Pathogenic mechanisms of the oncoprotein CagA in H. pylori-induced gastric cancer (Review)

Shuai-Yin Chen, Rong-Guang Zhang, Guang-Cai Duan
Pages: 3087-3094
Published online on: 04 October 2016

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Article Open Access

Extra-virgin olive oil phenols block cell cycle progression and modulate chemotherapeutic toxicity in bladder cancer cells

Andrea Coccia, Luciana Mosca, Rosa Puca, Giorgio Mangino, Alessandro Rossi, Eugenio Lendaro
Pages: 3095-3104
Published online on: 05 October 2016

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Article Open Access

Effect of RhoC on the epithelial-mesenchymal transition process induced by TGF-β1 in lung adenocarcinoma cells Retraction in /10.3892/or.2024.8702

Xiaoxiao Lu, Honglan Guo, Xi Chen, Jian Xiao, Yong Zou, Wei Wang, Qiong Chen
Pages: 3105-3112
Published online on: 04 October 2016

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Article Open Access

Role of HOTAIR in the diagnosis and prognosis of acute leukemia

Yuan-Yuan Zhang, Si-Han Huang, Hua-Rong Zhou, Cong‑Jie Chen, Li-Hong Tian, Jian-Zhen Shen
Pages: 3113-3122
Published online on: 04 October 2016

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Article Open Access

Effect of a novel oral chemotherapeutic agent containing a combination of trifluridine, tipiracil and the novel triple angiokinase inhibitor nintedanib, on human colorectal cancer xenografts

Norihiko Suzuki, Fumio Nakagawa, Kazuaki Matsuoka, Teiji Takechi
Pages: 3123-3130
Published online on: 27 October 2016

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Article Open Access

Comparative proteomic profiling identifies potential prognostic factors for human clear cell renal cell carcinoma

Xiang Sun, Hongwei Zhang, Longhua Luo, Kezhao Zhong, Yushui Ma, Linlin Fan, Da Fu, Lijuan Wan
Pages: 3131-3138
Published online on: 11 October 2016

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Article Open Access

Eribulin sensitizes oral squamous cell carcinoma cells to cetuximab via induction of mesenchymal-to-epithelial transition

Hiroko Kitahara, Mariko Hirai, Koroku Kato, George Bou-Gharios, Hiroyuki Nakamura, Shuichi Kawashiri
Pages: 3139-3144
Published online on: 21 October 2016

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Article Open Access

High expression of fibronectin is associated with poor prognosis, cell proliferation and malignancy via the NF-κB/p53-apoptosis signaling pathway in colorectal cancer

Wenzhong Yi, Enhua Xiao, Ru Ding, Ping Luo, Yi Yang
Pages: 3145-3153
Published online on: 17 October 2016

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Article Open Access

Myofibroblast distribution is associated with invasive growth types of colorectal cancer

Masafumi Takatsuna, Satoko Morohashi, Tadashi Yoshizawa, Hideaki Hirai, Toshihiro Haga, Rie Ota, Kensuke Saito, Yunyan Wu, Hiroko Seino, Yutaka Aoyagi, Shuji Terai, Hiroshi Kijima
Pages: 3154-3160
Published online on: 25 October 2016

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Article Open Access

Sulfatase 2 facilitates lymphangiogenesis in breast cancer by regulating VEGF-D

Chenfang Zhu, Xiaoliang Qi, Xin Zhou, Xin Nie, Yan Gu
Pages: 3161-3171
Published online on: 04 October 2016

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Article Open Access

Identification of a novel transcript isoform of the TTLL12 gene in human cancers

Ruiling Wen, Yingying Xiao, Yuhua Zhang, Min Yang, Yongping Lin, Jun Tang
Pages: 3172-3180
Published online on: 28 September 2016

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Article Open Access

Differential expression of filamin B splice variants in giant cell tumor cells

Joseph Chi-Ching Tsui, Carol Po-Ying Lau, Alex Chun Cheung, Kwok-Chuen Wong, Lin Huang, Stephen Kwok-Wing Tsui, Shekhar Madhukar Kumta
Pages: 3181-3187
Published online on: 24 October 2016

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Article

Microfluidic profiling of apoptosis-related genes after treatment with BH3-mimetic agents in astrocyte and glioblastoma cell lines

Eva Vidomanova, Peter Racay, Ivana Pilchova, Erika Halasova, Jozef Hatok
Pages: 3188-3196
Published online on: 21 October 2016

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Article

MicroRNA profiling in human breast cancer cell lines exposed to the anti-neoplastic drug cediranib

A.L.R. Bordinhão, A.F. Evangelista, R.J.S. Oliveira, T. Macedo, H.C. Silveira, R.M. Reis, M.M. Marques
Pages: 3197-3206
Published online on: 07 October 2016

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Article

Proton pump inhibitor pantoprazole inhibits the proliferation, self‑renewal and chemoresistance of gastric cancer stem cells via the EMT/β‑catenin pathways

Shuitu Feng, Zhigao Zheng, Lihua Feng, Lihong Yang, Zuhong Chen, Yubiao Lin, Yingqin Gao, Yide Chen
Pages: 3207-3214
Published online on: 07 October 2016

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Article

Extract of Caulis Spatholobi, a novel blocker targeting tumor cell‑induced platelet aggregation, inhibits breast cancer metastasis

Xi Chen, Qi Li, Xiao‑Xi Kan, Ya‑Jie Wang, Yu‑Jie Li, Qing Yang, Hong‑Bin Xiao, Ying Chen, Xiao‑Gang Weng, Wei‑Yan Cai, Xiao‑Xin Zhu
Pages: 3215-3224
Published online on: 19 October 2016

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Article

miR-300 promotes proliferation and EMT-mediated colorectal cancer migration and invasion by targeting p53

Lin Wang, Peiwu Yu
Pages: 3225-3232
Published online on: 21 October 2016

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Article

Pterostilbene inhibits hepatocellular carcinoma through p53/SOD2/ROS-mediated mitochondrial apoptosis

Liying Guo, Kai Tan, Hao Wang, Xuan Zhang
Pages: 3233-3240
Published online on: 05 October 2016

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Article

Decreased expression of long non-coding RNA GAS5 promotes cell proliferation, migration and invasion, and indicates a poor prognosis in ovarian cancer

Jie Li, He Huang, Yingguang Li, Li Li, Wenhui Hou, Zeshan You
Pages: 3241-3250
Published online on: 24 October 2016

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Article

Gefitinib enhances oxaliplatin-induced apoptosis mediated by Src and PKC-modulated gap junction function

Jian-Feng Wu, Jie Ji, Shu-Ying Dong, Bei-Bei Li, Mei-Ling Yu, Dan-Dan Wu, Liang Tao, Xu-Hui Tong
Pages: 3251-3258
Published online on: 11 October 2016

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Article

MicroRNA-124 inhibits cell proliferation and migration by regulating SNAI2 in breast cancer

Shanmei Du, Helou Li, Xiaochun Sun, Dongsheng Li, Yong Yang, Zehua Tao, Qian Li, Kui Liu
Pages: 3259-3266
Published online on: 11 October 2016

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Article

Effects and mechanism of RhoC downregulation in suppressing ovarian cancer stem cell proliferation, drug resistance, invasion and metastasis

Xiu-Bo Sang, Kai-Xuan Sun, Li-Li Wang, Shuo Chen, Dan‑Dan Wu, Zhi-Hong Zong, Yang Zhao
Pages: 3267-3274
Published online on: 11 October 2016

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Article

Let‑7a suppresses cell proliferation via the TGF‑β/SMAD signaling pathway in cervical cancer

Tianhui Wu, Xin Chen, Rui Peng, Handeng Liu, Pin Yin, Huimin Peng, Yujian Zhou, Yan Sun, Li Wen, Hong Yi, Ailing Li, Zheng Zhang
Pages: 3275-3282
Published online on: 11 October 2016

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Article

SurvivinT34A increases the therapeutic efficacy of arsenic trioxide in mouse hepatocellular carcinoma models

Anliang Huang, Dan Yue, Danying Liao, Liuliu Cheng, Jinhu Ma, Yuquan Wei, Aiping Tong, Ping Cheng
Pages: 3283-3290
Published online on: 11 October 2016

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Article

Comparative molecular analysis of early and late cancer cachexia-induced muscle wasting in mouse models

Rulin Sun, Santao Zhang, Xing Lu, Wenjun Hu, Ning Lou, Yan Zhao, Jia Zhou, Xiaoping Zhang, Hongmei Yang
Pages: 3291-3302
Published online on: 12 October 2016

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Article

CXCL5 promotes the proliferation and migration of glioma cells in autocrine- and paracrine-dependent manners Retraction in /10.3892/or.2021.8163

Zhijie Dai, Jun Wu, Fenghua Chen, Quan Cheng, Mingyu Zhang, Ying Wang, Yong Guo, Tao Song
Pages: 3303-3310
Published online on: 10 October 2016

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Article

TIPE2 suppresses the tumorigenesis, growth and metastasis of breast cancer via inhibition of the AKT and p38 signaling pathways

Zhenhua Zhang, Li Liu, Chunliang Liu, Shousong Cao, Yizhun Zhu, Qibing Mei
Pages: 3311-3316
Published online on: 21 October 2016

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Article

ST3Gal III modulates breast cancer cell adhesion and invasion by altering the expression of invasion-related molecules

Hong‑Xia Cui, Honglan Wang, Yuchun Wang, Juan Song, Hua Tian, Chunhui Xia, Yetong Shen
Pages: 3317-3324
Published online on: 18 October 2016

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Article

MicroRNA-455 regulates migration and invasion of human hepatocellular carcinoma by targeting Runx2

Le Qin, Yu Zhang, Jie Lin, Yangping Shentu, Xiaoxiao Xie
Pages: 3325-3332
Published online on: 30 September 2016

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Article

Expression status of CD44 and CD133 as a prognostic marker in esophageal squamous cell carcinoma treated with neoadjuvant chemotherapy followed by radical esophagectomy

Koichi Okamoto, Itasu Ninomiya, Yoshinao Ohbatake, Atsushi Hirose, Tomoya Tsukada, Shinichi Nakanuma, Seisho Sakai, Jun Kinoshita, Isamu Makino, Keishi Nakamura, Hironori Hayashi, Katsunobu Oyama, Masafumi Inokuchi, Hisatoshi Nakagawara, Tomoharu Miyashita, Tajima Hidehiro, Hiroyuki Takamura, Sachio Fushida, Tetsuo Ohta
Pages: 3333-3342
Published online on: 28 September 2016

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Article

Multivariate analysis of metastasis‑related risk factors for patients with gastroenteropancreatic neuroendocrine tumors based on clinicopathological and endoscopic features

Caiyun Tang, Lingqi Gong, Wenli Zou, Jie Zhang, Yuqian Zhou, Xiaoping Wu, Fanggen Lu, Chunhui Ouyang, Xiaowei Liu
Pages: 3343-3352
Published online on: 13 October 2016

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Article

Autophagy eliminates ER membrane reorganization induced by Bcl-2 inhibitor in HeLa cells

Xiaoning Li, Yongwei Kang, Bingxuan Jiao, Meihui Xia, Yao Wu, Liankun Sun
Pages: 3353-3362
Published online on: 27 October 2016

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Article

Fentanyl induces autophagy via activation of the ROS/MAPK pathway and reduces the sensitivity of cisplatin in lung cancer cells

Jiaqi Yao, Chi Ma, Wei Gao, Jinxiao Liang, Chang Liu, Hongfang Yang, Qiu Yan, Qingping Wen
Pages: 3363-3370
Published online on: 19 October 2016

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Article

Overexpression of miR-422a inhibits cell proliferation and invasion, and enhances chemosensitivity in osteosarcoma cells

Mingjiang Liu, He Xiusheng, Xiangjun Xiao, Yichun Wang
Pages: 3371-3378
Published online on: 19 October 2016

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Article

MicroRNA-20a-5p targets RUNX3 to regulate proliferation and migration of human hepatocellular cancer cells

Yanke Chen, Xiaofei Wang, Jiwen Cheng, Zhen Wang, Ting Jiang, Ni Hou, Na Liu, Tusheng Song, Chen Huang
Pages: 3379-3386
Published online on: 04 October 2016

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Article

miR-148a inhibits self-renewal of thyroid cancer stem cells via repressing INO80 expression

Weizhong Sheng, Yusheng Chen, Yuda Gong, Tiangeng Dong, Bo Zhang, Weidong Gao
Pages: 3387-3396
Published online on: 25 October 2016

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Article

Enhancement of radiosensitivity by inhibition of c-Jun N-terminal kinase activity in a Lewis lung carcinoma‑bearing subcutaneous tumor mouse model

Chun-Hao Li, Sa-Hoe Lim, Hyang-Hwa Ryu, Kyung‑Sub Moon, Tae-Young Jung, Shin Jung
Pages: 3397-3404
Published online on: 25 October 2016

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Article

Distinct expression profile of lncRNA in endometrial carcinoma

Juan Xu, Yujia Qian, Min Ye, Ziyi Fu, Xuemei Jia, Wenqu Li, Pengfei Xu, Mingming Lv, Lei Huang, Luyu Wang, Hongjie Ruan, Juan Lv
Pages: 3405-3412
Published online on: 14 October 2016

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Article

c-Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Pages: 3413-3420
Published online on: 13 October 2016

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Article

Gadolinium chloride elicits apoptosis in human osteosarcoma U-2 OS cells through extrinsic signaling, intrinsic pathway and endoplasmic reticulum stress

Yuh-Feng Tsai, Ching-Wen Huang, Jo-Hua Chiang, Fuu-Jen Tsai, Yuan-Man Hsu, Chi-Cheng Lu, Chen-Yu Hsiao, Jai-Sing Yang
Pages: 3421-3426
Published online on: 14 October 2016

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Article

Tumor-suppressive role of HACE1 in hepatocellular carcinoma and its clinical significance

Zeng-Fa Gao, Yong-Na Wu, Zhong-Tian Bai, Lei Zhang, Qi Zhou, Xun Li
Pages: 3427-3435
Published online on: 26 October 2016

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Article

Tissue metabolic profiling of lymph node metastasis of colorectal cancer assessed by 1H NMR

Hailong Zhang, Liang Qiao, Xiaopeng Li, Yang Wan, Li Yang, Huijuan Wang
Pages: 3436-3448
Published online on: 14 October 2016

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Article

Effects of RNAi-mediated MUC4 gene silencing on the proliferation and migration of human pancreatic carcinoma BxPC-3 cells

Yong Li, Changqiang Wu, Tianwu Chen, Juanjuan Zhang, Gang Liu, Yu Pu, Jiang Zhu, Chengyi Shen, Yang Zhang, Nanlin Zeng, Xiaoming Zhang
Pages: 3449-3455
Published online on: 06 October 2016

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Article

Overexpression of PCBP2 contributes to poor prognosis and enhanced cell growth in human hepatocellular carcinoma

Xiubing Zhang, Lu Hua, Daliang Yan, Fengbo Zhao, Jinxia Liu, Huiling Zhou, Jie Liu, Miaomiao Wu, Chengliang Zhang, Yingying Chen, Buyou Chen, Baoying Hu
Pages: 3456-3464
Published online on: 13 October 2016

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Article

Diphenhydramine induces melanoma cell apoptosis by suppressing STAT3/MCL-1 survival signaling and retards B16-F10 melanoma growth in vivo

Chi-Hung R. Or, Hong-Lin Su, Wee-Chyan Lee, Shu-Yi Yang, Cheesang Ho, Chia-Che Chang
Pages: 3465-3471
Published online on: 25 October 2016

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Article

Interaction between Treg cells and tumor-associated macrophages in the tumor microenvironment of epithelial ovarian cancer

Qinyi Zhu, Xiaoli Wu, Yueqian Wu, Xipeng Wang
Pages: 3472-3478
Published online on: 28 September 2016

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Article

Expression of LPA2 is associated with poor prognosis in human breast cancer and regulates HIF-1α expression and breast cancer cell growth

Min Li, Dong Xiao, Jia Zhang, Hangying Qu, Ya Yang, Yan Yan, Xu Liu, Jizhao Wang, Lin Liu, Jiansheng Wang, Xiaoyi Duan
Pages: 3479-3487
Published online on: 26 October 2016

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Article

Metformin potentiates the anticancer activities of gemcitabine and cisplatin against cholangiocarcinoma cells in vitro and in vivo

Hua-Qiang Zhu, Jin-Ben Ma, Xie Song, Heng-Jun Gao, Chao-Qun Ma, Hong Chang, Hong-Guang Li, Fang-Feng Liu, Jun Lu, Xu Zhou
Pages: 3488-3496
Published online on: 20 October 2016

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Article

Cortactin contributes to the tumorigenicity of colorectal cancer by promoting cell proliferation

Huo Wu, Xi Cheng, Xiaopin Ji, Yonggang He, Xiaoqian Jing, Haoxuan Wu, Ren Zhao
Pages: 3497-3503
Published online on: 27 October 2016

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Article

Angelicin inhibits human lung carcinoma A549 cell growth and migration through regulating JNK and ERK pathways

Guangcai Li, Yuan He, Jun Yao, Chuying Huang, Xiusheng Song, Yan Deng, Sheng Xie, Jie Ren, Meng Jin, Huiguo Liu
Pages: 3504-3512
Published online on: 12 October 2016

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Article

Bax-interacting factor-1 inhibits cell proliferation and promotes apoptosis in prostate cancer cells

Lin Xu, Zhu Wang, Shan-Yang He, Su-Fen Zhang, Hong-Jiao Luo, Kai Zhou, Xiao-Fei Li, Shao-Peng Qiu, Kai-Yuan Cao
Pages: 3513-3521
Published online on: 14 October 2016

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Article

Hypoxia and macrophages promote glioblastoma invasion by the CCL4-CCR5 axis Expression of Concern in /10.3892/or.2025.8989

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Pages: 3522-3528
Published online on: 13 October 2016

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Article

microRNA-520a-3p inhibits proliferation and cancer stem cell phenotype by targeting HOXD8 in non-small cell lung cancer

Ying Liu, Lijun Miao, Ran Ni, Hui Zhang, Ling Li, Xinhua Wang, Xin Li, Jing Wang
Pages: 3529-3535
Published online on: 05 October 2016

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Article

Effects of phycoerythrin from Gracilaria lemaneiformis in proliferation and apoptosis of SW480 cells

Peizhen Li, Jun Ying, Qingli Chang, Wen Zhu, Guangjian Yang, Teng Xu, Huiguang Yi, Ruowang Pan, Enyong Zhang, Xiaofeng Zeng, Chunxia Yan, Qiyu Bao, Shengbin Li
Pages: 3536-3544
Published online on: 11 October 2016

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Article

Anticancer effect of thalidomide in vitro on human osteosarcoma cells

Jianwei Zhu, Ya Yang, Sihong Liu, Huihua Xu, Yong Wu, Guiqiang Zhang, Yuxuan Wang, Yan Wang, Yamin Liu, Qifeng Guo
Pages: 3545-3551
Published online on: 11 October 2016

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Article

miR-100 resensitizes resistant epithelial ovarian cancer to cisplatin

Peng Guo, Xiangpeng Xiong, Sainan Zhang, Dongxian Peng
Pages: 3552-3558
Published online on: 03 October 2016

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Article

Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway

Xiang-Jun Fan, Yao Wang, Lei Wang, Mingyan Zhu
Pages: 3559-3567
Published online on: 30 September 2016

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Article

Pien Tze Huang suppresses VEGF-C-mediated lymphangiogenesis in colorectal cancer

Jiumao Lin, Jianyu Feng, Yiyi Jin, Zhaokun Yan, Zijun Lai, Jun Peng
Pages: 3568-3576
Published online on: 20 October 2016

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Article

Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces apoptosis via Fas-mediated pathway in HL-60 human leukemia cells

Eun Young Park, Joo-Il Kim, Dong-Gyu Leem, Ji-Sun Shin, Kyung-Tack Kim, Sang Yoon Choi, Myung-Hee Lee, Jung-Hye Choi, Yong Sup Lee, Kyung-Tae Lee
Pages: 3577-3587
Published online on: 13 October 2016

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Article

Upregulated CTHRC1 promotes human epithelial ovarian cancer invasion through activating EGFR signaling

Jun Ye, Wei Chen, Zhi-Yong Wu, Jin-Hui Zhang, He Fei, Li-Wen Zhang, Ya-Hui Wang, Ya-Ping Chen, Xiao-Mei Yang
Pages: 3588-3596
Published online on: 24 October 2016

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Downregulation of DNMT3a expression increases miR-182-induced apoptosis of ovarian cancer through caspase-3 and caspase-9-mediated apoptosis and DNA damage response

Wei Lu, Tanmin Lu, Xin Wei
Pages: 3597-3604
Published online on: 28 September 2016

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Dysregulation of micro-143-3p and BALBP1 contributes to the pathogenesis of the development of ovarian carcinoma

Hongyan Zhang, Wanbin Li
Pages: 3605-3610
Published online on: 04 October 2016

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Article

Gambogenic acid induces proteasomal degradation of CIP2A and sensitizes hepatocellular carcinoma to anticancer agents

Xian‑Jun Yu, Qun Zhao, Xuan‑Bin Wang, Jing‑Xuan Zhang, Xiao‑Bo Wang
Pages: 3611-3618
Published online on: 20 October 2016

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Article

Angiomotin promotes the malignant potential of colon cancer cells by activating the YAP-ERK/PI3K-AKT signaling pathway

Yan Zhang, Jun Yuan, Xinli Zhang, Futang Yan, Minggang Huang, Tao Wang, Xiao Zheng, Ming Zhang
Pages: 3619-3626
Published online on: 21 October 2016

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Article

In silico RNA-seq and experimental analyses reveal the differential expression and splicing of EPDR1 and ZNF518B genes in relation to KRAS mutations in colorectal cancer cells

Ángela L. Riffo-Campos, Josefa Castillo, Azahara Vallet-Sánchez, Guillermo Ayala, Andrés Cervantes, Gerardo López-Rodas, Luis Franco
Pages: 3627-3634
Published online on: 27 October 2016

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Article

Effect of colorectal cancer on the number of normal stem cells circulating in peripheral blood

Wojciech Marlicz, Katarzyna Sielatycka, Karol Serwin, Ewa Kubis, Marta Tkacz, Rafał Głuszko, Andrzej Białek, Teresa Starzyńska, Mariusz Z. Ratajczak
Pages: 3635-3642
Published online on: 18 October 2016

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Article

Idelalisib induces G1 arrest and apoptosis in chronic myeloid leukemia K562 cells

Yali Chen, Qianxiang Zhou, Lei Zhang, Ran Wang, Meihua Jin, Yuling Qiu, Dexin Kong
Pages: 3643-3650
Published online on: 17 October 2016

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Article

Downregulation of microRNA‑574 in cancer stem cells causes recurrence of prostate cancer via targeting REL

Xiaodong Lai, Yanchun Guo, Zhitao Guo, Ruibao Liu, Xunguo Wang, Fang Wang
Pages: 3651-3656
Published online on: 24 October 2016

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Article

miR-4262 promotes the proliferation of human cutaneous malignant melanoma cells through KLF6-mediated EGFR inactivation and p21 upregulation

Dingwei Zhang, Zhangjun Li, Yanfei Zhang, Chen Tu, Jia Huo, Yan Liu
Pages: 3657-3663
Published online on: 21 October 2016

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Article

HPIP promotes gastric cancer cell proliferation through activation of cap-dependent translation

Bing Chen, Jin Zhao, Shengbin Zhang, Yonggang Zhang, Zonghai Huang
Pages: 3664-3672
Published online on: 11 October 2016

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Article

Differential glycolytic profile and Warburg effect in papillary thyroid carcinoma cell lines

Raquel Guimarães Coelho, Juliana de Menezes Cazarin, João Paulo Albuquerque Cavalcanti de Albuquerque, Bruno Moulin de Andrade, Denise P. Carvalho
Pages: 3673-3681
Published online on: 04 October 2016

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Downregulation of YEATS4 by miR-218 sensitizes colorectal cancer cells to L-OHP-induced cell apoptosis by inhibiting cytoprotective autophagy

Qiang Fu, Jing Cheng, Jindai Zhang, Yonglei Zhang, Xiaobing Chen, Jianguo Xie, Suxia Luo
Pages: 3682-3690
Published online on: 21 October 2016

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Article

miR-27a-mediated antiproliferative effects of metformin on the breast cancer cell line MCF-7

Wei Zhao, Xiaohui Zhang, Jia Liu, Bei Sun, Hua Tang, Hong Zhang
Pages: 3691-3699
Published online on: 24 October 2016

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Article

Comparative proteomic analysis of melanosis coli with colon cancer

Xin Zhou, Ping Wang, Ying-Jian Zhang, Jin-Jin Xu, La-Mei Zhang, Lin Zhu, Li-Ping Xu, Xiao-Min Liu, Huan-Huan Su
Pages: 3700-3706
Published online on: 17 October 2016

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Article

MicroRNA-382 inhibits prostate cancer cell proliferation and metastasis through targeting COUP-TFII

Wei Zhang, Jianzhou Liu, Jianxin Qiu, Xiaoliang Fu, Qisheng Tang, Fan Yang, Zhiguang Zhao, He Wang
Pages: 3707-3715
Published online on: 03 October 2016

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Retraction Open Access

[Retracted] Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1-RAGE and Akt pathways in vitro and in vivo

Jing Zhang, Jin-Shui Zhu, Zhou Zhou, Wei-Xiong Chen, Ni-Wei Chen
Pages: 3716-3716
Published online on: 19 October 2016

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Correction Open Access

[Corrigendum] Carnosic acid induces apoptosis through inactivation of Src/STAT3 signaling pathway in human renal carcinoma Caki cells

Ji Eun Park, Byoungduck Park, In Gyeong Chae, Do-Hee Kim, Juthika Kundu, Joydeb Kumar Kundu, Kyung-Soo Chun
Pages: 3717-3717
Published online on: 29 September 2016

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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