|
1
|
Seeree P, Pearngam P, Kumkate S and
Janvilisri T: An omics perspective on molecular biomarkers for
diagnosis, prognosis, and therapeutics of cholangiocarcinoma. Int J
Genomics. 2015:1795282015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Razumilava N and Gores GJ:
Cholangiocarcinoma. Lancet. 383:2168–2179. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Bergquist A and von Seth E: Epidemiology
of cholangiocarcinoma. Best Pract Res Clin Gastroenterol.
29:221–232. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Welcker M and Clurman BE: FBW7 ubiquitin
ligase: A tumour suppressor at the crossroads of cell division,
growth and differentiation. Nat Rev Cancer. 8:83–93. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Wang L, Ye X, Liu Y, Wei W and Wang Z:
Aberrant regulation of FBW7 in cancer. Oncotarget. 5:2000–2015.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Spruck CH, Strohmaier H, Sangfelt O,
Müller HM, Hubalek M, Müller-Holzner E, Marth C, Widschwendter M
and Reed SI: hCDC4 gene mutations in endometrial cancer. Cancer
Res. 62:4535–4539. 2002.PubMed/NCBI
|
|
7
|
Welcker M, Orian A, Grim JE, Eisenman RN
and Clurman BE: A nucleolar isoform of the Fbw7 ubiquitin ligase
regulates c-Myc and cell size. Curr Biol. 14:1852–1857. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Grim JE, Gustafson MP, Hirata RK, Hagar
AC, Swanger J, Welcker M, Hwang HC, Ericsson J, Russell DW and
Clurman BE: Isoform- and cell cycle-dependent substrate degradation
by the Fbw7 ubiquitin ligase. J Cell Biol. 181:913–920. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Matsumoto A, Onoyama I and Nakayama KI:
Expression of mouse Fbxw7 isoforms is regulated in a cell cycle- or
p53-dependent manner. Biochem Biophys Res Commun. 350:114–119.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Yada M, Hatakeyama S, Kamura T, Nishiyama
M, Tsunematsu R, Imaki H, Ishida N, Okumura F, Nakayama K and
Nakayama KI: Phosphorylation-dependent degradation of c-Myc is
mediated by the F-box protein Fbw7. EMBO J. 23:2116–2125. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Koepp DM, Schaefer LK, Ye X, Keyomarsi K,
Chu C, Harper JW and Elledge SJ: Phosphorylation-dependent
ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
Science. 294:173–177. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Mao JH, Kim IJ, Wu D, Climent J, Kang HC,
DelRosario R and Balmain A: FBXW7 targets mTOR for degradation and
cooperates with PTEN in tumor suppression. Science. 321:1499–1502.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Inuzuka H, Shaik S, Onoyama I, Gao D,
Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, et al:
SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for
ubiquitylation and destruction. Nature. 471:104–109. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Tsunematsu R, Nakayama K, Oike Y,
Nishiyama M, Ishida N, Hatakeyama S, Bessho Y, Kageyama R, Suda T
and Nakayama KI: Mouse Fbw7/Sel-10/Cdc4 is required for notch
degradation during vascular development. J Biol Chem.
279:9417–9423. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Wu G, Lyapina S, Das I, Li J, Gurney M,
Pauley A, Chui I, Deshaies RJ and Kitajewski J: SEL-10 is an
inhibitor of notch signaling that targets notch for
ubiquitin-mediated protein degradation. Mol Cell Biol.
21:7403–7415. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Wu RC, Feng Q, Lonard DM and O'Malley BW:
SRC-3 coactivator functional lifetime is regulated by a
phospho-dependent ubiquitin time clock. Cell. 129:1125–1140. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Akhoondi S, Sun D, von der Lehr N,
Apostolidou S, Klotz K, Maljukova A, Cepeda D, Fiegl H, Dafou D,
Marth C, et al: FBXW7/hCDC4 is a general tumor suppressor in human
cancer. Cancer Res. 67:9006–9012. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Yang H, Lu X, Liu Z, Chen L, Xu Y, Wang Y,
Wei G and Chen Y: FBXW7 suppresses epithelial-mesenchymal
transition, stemness and metastatic potential of cholangiocarcinoma
cells. Oncotarget. 6:6310–6325. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Barsotti AM and Prives C:
Pro-proliferative FoxM1 is a target of p53-mediated repression.
Oncogene. 28:4295–4305. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yang C, Li S, Wang M, Chang AK, Liu Y,
Zhao F, Xiao L, Han L, Wang D, Li S, et al: PTEN suppresses the
oncogenic function of AIB1 through decreasing its protein stability
via mechanism involving Fbw7 alpha. Mol Cancer. 12:212013.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
van Drogen F, Sangfelt O, Malyukova A,
Matskova L, Yeh E, Means AR and Reed SI: Ubiquitylation of cyclin E
requires the sequential function of SCF complexes containing
distinct hCdc4 isoforms. Mol Cell. 23:37–48. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wang R, Wang Y, Liu N, Ren C, Jiang C,
Zhang K, Yu S, Chen Y, Tang H, Deng Q, et al: FBW7 regulates
endothelial functions by targeting KLF2 for ubiquitination and
degradation. Cell Res. 23:803–819. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Gartel AL and Radhakrishnan SK: Lost in
transcription: p21 repression, mechanisms, and consequences. Cancer
Res. 65:3980–3985. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Bretones G, Delgado MD and León J: Myc and
cell cycle control. Biochim Biophys Acta. 1849:506–516. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ishikawa Y, Hosogane M, Okuyama R, Aoyama
S, Onoyama I, Nakayama KI and Nakayama K: Opposing functions of
Fbxw7 in keratinocyte growth, differentiation and skin
tumorigenesis mediated through negative regulation of c-Myc and
Notch. Oncogene. 32:1921–1932. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Onoyama I, Tsunematsu R, Matsumoto A,
Kimura T, de A, lborán IM, Nakayama K and Nakayama KI: Conditional
inactivation of Fbxw7 impairs cell-cycle exit during T cell
differentiation and results in lymphomatogenesis. J Exp Med.
204:2875–2888. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Matsuoka S, Oike Y, Onoyama I, Iwama A,
Arai F, Takubo K, Mashimo Y, Oguro H, Nitta E, Ito K, et al: Fbxw7
acts as a critical fail-safe against premature loss of
hematopoietic stem cells and development of T-ALL. Genes Dev.
22:986–991. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Ishikawa Y, Onoyama I, Nakayama KI and
Nakayama K: Notch-dependent cell cycle arrest and apoptosis in
mouse embryonic fibroblasts lacking Fbxw7. Oncogene. 27:6164–6174.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Masuda K, Ishikawa Y, Onoyama I, Unno M,
de A, lborán IM, Nakayama KI and Nakayama K: Complex regulation of
cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts.
Oncogene. 29:1798–1809. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Yang H, Li TW, Ko KS, Xia M and Lu SC:
Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression
and apoptosis during cholestasis in mouse and human hepatocytes.
Hepatology. 49:860–870. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Prakobwong S, Khoontawad J, Yongvanit P,
Pairojkul C, Hiraku Y, Sithithaworn P, Pinlaor P, Aggarwal BB and
Pinlaor S: Curcumin decreases cholangiocarcinogenesis in hamsters
by suppressing inflammation-mediated molecular events related to
multistep carcinogenesis. Int J Cancer. 129:88–100. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Yang H, Li TW, Peng J, Tang X, Ko KS, Xia
M and Aller MA: A mouse model of cholestasis-associated
cholangiocarcinoma and transcription factors involved in
progression. Gastroenterology. 141:378–388, 388.e1-4. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Lin CP, Liu JD, Chow JM, Liu CR and Liu
HE: Small-molecule c-Myc inhibitor, 10058-F4, inhibits
proliferation, downregulates human telomerase reverse transcriptase
and enhances chemosensitivity in human hepatocellular carcinoma
cells. Anticancer Drugs. 18:161–170. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Huang MJ, Cheng YC, Liu CR, Lin S and Liu
HE: A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle
arrest, apoptosis, and myeloid differentiation of human acute
myeloid leukemia. Exp Hematol. 34:1480–1489. 2006. View Article : Google Scholar : PubMed/NCBI
|
